-
1
-
-
84865620494
-
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
-
Thompson LH, (2012) Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography. Mutat Res 751: 158-246.
-
(2012)
Mutat Res
, vol.751
, pp. 158-246
-
-
Thompson, L.H.1
-
2
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan ME, Jasin M, (2010) Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 11: 196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
3
-
-
68249150701
-
Mre11: roles in DNA repair beyond homologous recombination
-
Zha S, Boboila C, Alt FW, (2009) Mre11: roles in DNA repair beyond homologous recombination. Nat Struct Mol Biol 16: 798-800.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 798-800
-
-
Zha, S.1
Boboila, C.2
Alt, F.W.3
-
4
-
-
54849404458
-
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
-
McVey M, Lee SE, (2008) MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet 24: 529-538.
-
(2008)
Trends Genet
, vol.24
, pp. 529-538
-
-
McVey, M.1
Lee, S.E.2
-
5
-
-
79956215808
-
Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways
-
Mladenov E, Iliakis G, (2011) Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways. Mutat Res 711: 61-72.
-
(2011)
Mutat Res
, vol.711
, pp. 61-72
-
-
Mladenov, E.1
Iliakis, G.2
-
6
-
-
36949013395
-
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
-
Lavin MF, (2007) ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene 26: 7749-7758.
-
(2007)
Oncogene
, vol.26
, pp. 7749-7758
-
-
Lavin, M.F.1
-
7
-
-
77951057068
-
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
-
Bothmer A, Robbiani DF, Feldhahn N, Gazumyan A, Nussenzweig A, et al. (2010) 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J Exp Med 207: 855-865.
-
(2010)
J Exp Med
, vol.207
, pp. 855-865
-
-
Bothmer, A.1
Robbiani, D.F.2
Feldhahn, N.3
Gazumyan, A.4
Nussenzweig, A.5
-
8
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, et al. (2010) 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 17: 688-695.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
-
9
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting SF, Callen E, Wong N, Chen HT, Polato F, et al. (2010) 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 141: 243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
-
10
-
-
68949221567
-
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency
-
Cao L, Xu X, Bunting SF, Liu J, Wang RH, et al. (2009) A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. Mol Cell 35: 534-541.
-
(2009)
Mol Cell
, vol.35
, pp. 534-541
-
-
Cao, L.1
Xu, X.2
Bunting, S.F.3
Liu, J.4
Wang, R.H.5
-
11
-
-
78651406669
-
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes
-
Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, et al. (2011) H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature 469: 245-249.
-
(2011)
Nature
, vol.469
, pp. 245-249
-
-
Helmink, B.A.1
Tubbs, A.T.2
Dorsett, Y.3
Bednarski, J.J.4
Walker, L.M.5
-
12
-
-
80053447704
-
Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 Is required for homologous recombination repair of double-strand breaks
-
doi:10.1371/journal.pgen.1002271
-
Langerak P, Mejia-Ramirez E, Limbo O, Russell P, (2011) Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 Is required for homologous recombination repair of double-strand breaks. PLoS Genet 7: e1002271 doi:10.1371/journal.pgen.1002271.
-
(2011)
PLoS Genet
, vol.7
-
-
Langerak, P.1
Mejia-Ramirez, E.2
Limbo, O.3
Russell, P.4
-
13
-
-
84863152463
-
Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex
-
Sun J, Lee KJ, Davis AJ, Chen DJ, (2012) Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex. J Biol Chem 287: 4936-4945.
-
(2012)
J Biol Chem
, vol.287
, pp. 4936-4945
-
-
Sun, J.1
Lee, K.J.2
Davis, A.J.3
Chen, D.J.4
-
14
-
-
79952762235
-
Factors determining DNA double-strand break repair pathway choice in G2 phase
-
Shibata A, Conrad S, Birraux J, Geuting V, Barton O, et al. (2011) Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO J 30: 1079-1092.
-
(2011)
EMBO J
, vol.30
, pp. 1079-1092
-
-
Shibata, A.1
Conrad, S.2
Birraux, J.3
Geuting, V.4
Barton, O.5
-
15
-
-
52949149420
-
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair
-
Williams RS, Moncalian G, Williams JS, Yamada Y, Limbo O, et al. (2008) Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell 135: 97-109.
-
(2008)
Cell
, vol.135
, pp. 97-109
-
-
Williams, R.S.1
Moncalian, G.2
Williams, J.S.3
Yamada, Y.4
Limbo, O.5
-
16
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, et al. (2007) Human CtIP promotes DNA end resection. Nature 450: 509-514.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
-
17
-
-
72149103012
-
CtIP links DNA double-strand break sensing to resection
-
You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, et al. (2009) CtIP links DNA double-strand break sensing to resection. Mol Cell 36: 954-969.
-
(2009)
Mol Cell
, vol.36
, pp. 954-969
-
-
You, Z.1
Shi, L.Z.2
Zhu, Q.3
Wu, P.4
Zhang, Y.W.5
-
18
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
-
Yun MH, Hiom K, (2009) CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 459: 460-463.
-
(2009)
Nature
, vol.459
, pp. 460-463
-
-
Yun, M.H.1
Hiom, K.2
-
19
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou EP, Symington LS, (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455: 770-774.
-
(2008)
Nature
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
20
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu Z, Chung WH, Shim EY, Lee SE, Ira G, (2008) Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134: 981-994.
-
(2008)
Cell
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
-
21
-
-
84859004905
-
Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions
-
Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, et al. (2012) Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair (Amst) 11: 441-448.
-
(2012)
DNA Repair (Amst)
, vol.11
, pp. 441-448
-
-
Tomimatsu, N.1
Mukherjee, B.2
Deland, K.3
Kurimasa, A.4
Bolderson, E.5
-
22
-
-
68249138694
-
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
-
Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, et al. (2009) Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells. Nat Struct Mol Biol 16: 819-824.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 819-824
-
-
Rass, E.1
Grabarz, A.2
Plo, I.3
Gautier, J.4
Bertrand, P.5
-
23
-
-
68249146431
-
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
-
Xie A, Kwok A, Scully R, (2009) Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat Struct Mol Biol 16: 814-818.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 814-818
-
-
Xie, A.1
Kwok, A.2
Scully, R.3
-
24
-
-
71049189711
-
Exonuclease function of human Mre11 promotes deletional nonhomologous end joining
-
Zhuang J, Jiang G, Willers H, Xia F, (2009) Exonuclease function of human Mre11 promotes deletional nonhomologous end joining. J Biol Chem 284: 30565-30573.
-
(2009)
J Biol Chem
, vol.284
, pp. 30565-30573
-
-
Zhuang, J.1
Jiang, G.2
Willers, H.3
Xia, F.4
-
25
-
-
80053212145
-
Human Mre11/human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway
-
Della-Maria J, Zhou Y, Tsai MS, Kuhnlein J, Carney JP, et al. (2011) Human Mre11/human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. J Biol Chem 286: 33845-33853.
-
(2011)
J Biol Chem
, vol.286
, pp. 33845-33853
-
-
Della-Maria, J.1
Zhou, Y.2
Tsai, M.S.3
Kuhnlein, J.4
Carney, J.P.5
-
26
-
-
78650995499
-
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
-
Zhang Y, Jasin M, (2011) An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat Struct Mol Biol 18: 80-84.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 80-84
-
-
Zhang, Y.1
Jasin, M.2
-
27
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
doi:10.1371/journal.pgen.1000110
-
Bennardo N, Cheng A, Huang N, Stark JM, (2008) Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet 4: e1000110 doi:10.1371/journal.pgen.1000110.
-
(2008)
PLoS Genet
, vol.4
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
28
-
-
77449090212
-
The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis
-
Taylor EM, Cecillon SM, Bonis A, Chapman JR, Povirk LF, et al. (2010) The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis. Nucleic Acids Res 38: 441-454.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 441-454
-
-
Taylor, E.M.1
Cecillon, S.M.2
Bonis, A.3
Chapman, J.R.4
Povirk, L.F.5
-
29
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, et al. (2007) IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449: 478-482.
-
(2007)
Nature
, vol.449
, pp. 478-482
-
-
Yan, C.T.1
Boboila, C.2
Souza, E.K.3
Franco, S.4
Hickernell, T.R.5
-
30
-
-
38049187905
-
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
-
Guirouilh-Barbat J, Rass E, Plo I, Bertrand P, Lopez BS, (2007) Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc Natl Acad Sci U S A 104: 20902-20907.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20902-20907
-
-
Guirouilh-Barbat, J.1
Rass, E.2
Plo, I.3
Bertrand, P.4
Lopez, B.S.5
-
31
-
-
2942525595
-
Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells
-
Guirouilh-Barbat J, Huck S, Bertrand P, Pirzio L, Desmaze C, et al. (2004) Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells. Mol Cell 14: 611-623.
-
(2004)
Mol Cell
, vol.14
, pp. 611-623
-
-
Guirouilh-Barbat, J.1
Huck, S.2
Bertrand, P.3
Pirzio, L.4
Desmaze, C.5
-
32
-
-
0037188898
-
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
-
Zhu C, Mills KD, Fergusion DO, Lee C, Manis J, et al. (2002) Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 109: 811-821.
-
(2002)
Cell
, vol.109
, pp. 811-821
-
-
Zhu, C.1
Mills, K.D.2
Fergusion, D.O.3
Lee, C.4
Manis, J.5
-
33
-
-
34547589577
-
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70
-
Weinstock DM, Brunet E, Jasin M, (2007) Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat Cell Biol 9: 978-981.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 978-981
-
-
Weinstock, D.M.1
Brunet, E.2
Jasin, M.3
-
34
-
-
80755187806
-
Double-strand break end resection and repair pathway choice
-
Symington LS, Gautier J, (2011) Double-strand break end resection and repair pathway choice. Annu Rev Genet 45: 247-271.
-
(2011)
Annu Rev Genet
, vol.45
, pp. 247-271
-
-
Symington, L.S.1
Gautier, J.2
-
35
-
-
77953166592
-
γH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization
-
Lobrich M, Shibata A, Beucher A, Fisher A, Ensminger M, et al. (2010) γH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle 9: 662-669.
-
(2010)
Cell Cycle
, vol.9
, pp. 662-669
-
-
Lobrich, M.1
Shibata, A.2
Beucher, A.3
Fisher, A.4
Ensminger, M.5
-
36
-
-
79957686784
-
Unrepaired clustered DNA lesions induce chromosome breakage in human cells
-
Asaithamby A, Hu B, Chen DJ, (2011) Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc Natl Acad Sci U S A 108: 8293-8298.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 8293-8298
-
-
Asaithamby, A.1
Hu, B.2
Chen, D.J.3
-
37
-
-
0024419461
-
Association among DNA/chromosome break rejoining rates, chromatin structure alterations, and radiation sensitivity in human tumor cell lines
-
Schwartz JL, Vaughan AT, (1989) Association among DNA/chromosome break rejoining rates, chromatin structure alterations, and radiation sensitivity in human tumor cell lines. Cancer Res 49: 5054-5057.
-
(1989)
Cancer Res
, vol.49
, pp. 5054-5057
-
-
Schwartz, J.L.1
Vaughan, A.T.2
-
38
-
-
0034437901
-
Complexity of damage produced by ionizing radiation
-
Ward JF, (2000) Complexity of damage produced by ionizing radiation. Cold Spring Harb Symp Quant Biol 65: 377-382.
-
(2000)
Cold Spring Harb Symp Quant Biol
, vol.65
, pp. 377-382
-
-
Ward, J.F.1
-
40
-
-
79952314830
-
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair
-
Chiolo I, Minoda A, Colmenares SU, Polyzos A, Costes SV, et al. (2011) Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell 144: 732-744.
-
(2011)
Cell
, vol.144
, pp. 732-744
-
-
Chiolo, I.1
Minoda, A.2
Colmenares, S.U.3
Polyzos, A.4
Costes, S.V.5
-
41
-
-
70350763838
-
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
-
Beucher A, Birraux J, Tchouandong L, Barton O, Shibata A, et al. (2009) ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J 28: 3413-3427.
-
(2009)
EMBO J
, vol.28
, pp. 3413-3427
-
-
Beucher, A.1
Birraux, J.2
Tchouandong, L.3
Barton, O.4
Shibata, A.5
-
42
-
-
33749534161
-
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
-
Blackburn EH, Greider CW, Szostak JW, (2006) Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 12: 1133-1138.
-
(2006)
Nat Med
, vol.12
, pp. 1133-1138
-
-
Blackburn, E.H.1
Greider, C.W.2
Szostak, J.W.3
-
43
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W, de Lange T, (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42: 301-334.
-
(2008)
Annu Rev Genet
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
44
-
-
84871749525
-
Mechanisms of telomere loss and their consequences for chromosome instability
-
Muraki K, Nyhan K, Han L, Murnane JP, (2012) Mechanisms of telomere loss and their consequences for chromosome instability. Front Oncol 2: 135.
-
(2012)
Front Oncol
, vol.2
, pp. 135
-
-
Muraki, K.1
Nyhan, K.2
Han, L.3
Murnane, J.P.4
-
45
-
-
33747882534
-
Telomeres and chromosome instability
-
Murnane JP, (2006) Telomeres and chromosome instability. DNA Repair (Amst) 5: 1082-1092.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 1082-1092
-
-
Murnane, J.P.1
-
46
-
-
77953161582
-
Telomere loss as a mechanism for chromosomal instability in human cancer
-
Murnane JP, (2010) Telomere loss as a mechanism for chromosomal instability in human cancer. Cancer Res 70: 4255-4259.
-
(2010)
Cancer Res
, vol.70
, pp. 4255-4259
-
-
Murnane, J.P.1
-
47
-
-
77955995270
-
Apollo contributes to G overhang maintenance and protects leading-end telomeres
-
Wu P, van Overbeek M, Rooney S, de Lange T, (2010) Apollo contributes to G overhang maintenance and protects leading-end telomeres. Mol Cell 39: 606-617.
-
(2010)
Mol Cell
, vol.39
, pp. 606-617
-
-
Wu, P.1
van Overbeek, M.2
Rooney, S.3
de Lange, T.4
-
48
-
-
77954958459
-
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
-
Lam YC, Akhter S, Gu P, Ye J, Poulet A, et al. (2010) SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. EMBO J 29: 2230-2241.
-
(2010)
EMBO J
, vol.29
, pp. 2230-2241
-
-
Lam, Y.C.1
Akhter, S.2
Gu, P.3
Ye, J.4
Poulet, A.5
-
49
-
-
2942644725
-
The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
-
Larrivee M, LeBel C, Wellinger RJ, (2004) The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes Dev 18: 1391-1396.
-
(2004)
Genes Dev
, vol.18
, pp. 1391-1396
-
-
Larrivee, M.1
LeBel, C.2
Wellinger, R.J.3
-
50
-
-
33645800789
-
The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres
-
Chai W, Sfeir AJ, Hoshiyama H, Shay JW, Wright WE, (2006) The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres. EMBO Rep 7: 225-230.
-
(2006)
EMBO Rep
, vol.7
, pp. 225-230
-
-
Chai, W.1
Sfeir, A.J.2
Hoshiyama, H.3
Shay, J.W.4
Wright, W.E.5
-
51
-
-
68949149732
-
Multiple roles for MRE11 at uncapped telomeres
-
Deng Y, Guo X, Ferguson DO, Chang S, (2009) Multiple roles for MRE11 at uncapped telomeres. Nature 460: 914-918.
-
(2009)
Nature
, vol.460
, pp. 914-918
-
-
Deng, Y.1
Guo, X.2
Ferguson, D.O.3
Chang, S.4
-
52
-
-
84863622662
-
Telomeric 3′ overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST
-
Wu P, Takai H, de Lange T, (2012) Telomeric 3′ overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell 150: 39-52.
-
(2012)
Cell
, vol.150
, pp. 39-52
-
-
Wu, P.1
Takai, H.2
de Lange, T.3
-
53
-
-
33745685066
-
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
-
Hockemeyer D, Daniels JP, Takai H, de Lange T, (2006) Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 126: 63-77.
-
(2006)
Cell
, vol.126
, pp. 63-77
-
-
Hockemeyer, D.1
Daniels, J.P.2
Takai, H.3
de Lange, T.4
-
54
-
-
33745713451
-
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
-
Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, et al. (2006) Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell 126: 49-62.
-
(2006)
Cell
, vol.126
, pp. 49-62
-
-
Wu, L.1
Multani, A.S.2
He, H.3
Cosme-Blanco, W.4
Deng, Y.5
-
55
-
-
34547670213
-
Telomere protection by mammalian Pot1 requires interaction with Tpp1
-
Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, et al. (2007) Telomere protection by mammalian Pot1 requires interaction with Tpp1. Nat Struct Mol Biol 14: 754-761.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 754-761
-
-
Hockemeyer, D.1
Palm, W.2
Else, T.3
Daniels, J.P.4
Takai, K.K.5
-
56
-
-
79955116929
-
Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair
-
Miller D, Reynolds GE, Mejia R, Stark JM, Murnane JP, (2011) Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair. DNA Repair (Amst) 10: 536-544.
-
(2011)
DNA Repair (Amst)
, vol.10
, pp. 536-544
-
-
Miller, D.1
Reynolds, G.E.2
Mejia, R.3
Stark, J.M.4
Murnane, J.P.5
-
57
-
-
19344374569
-
The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
-
doi:10.1371/journal.pbio.0020240
-
Karlseder J, Hoke K, Mirzoeva OK, Bakkenist C, Kastan MB, et al. (2004) The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. PLoS Biol 2: e240 doi:10.1371/journal.pbio.0020240.
-
(2004)
PLoS Biol
, vol.2
-
-
Karlseder, J.1
Hoke, K.2
Mirzoeva, O.K.3
Bakkenist, C.4
Kastan, M.B.5
-
58
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti R, Garcia-Cao M, Blasco MA, (2007) Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 39: 243-250.
-
(2007)
Nat Genet
, vol.39
, pp. 243-250
-
-
Benetti, R.1
Garcia-Cao, M.2
Blasco, M.A.3
-
59
-
-
33644502519
-
Telomere position effect and silencing of transgenes near telomeres in the mouse
-
Pedram M, Sprung CN, Gao Q, Lo AW, Reynolds GE, et al. (2006) Telomere position effect and silencing of transgenes near telomeres in the mouse. Mol Cell Biol 26: 1865-1878.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1865-1878
-
-
Pedram, M.1
Sprung, C.N.2
Gao, Q.3
Lo, A.W.4
Reynolds, G.E.5
-
60
-
-
70350455474
-
The mre11 complex and the response to dysfunctional telomeres
-
Attwooll CL, Akpinar M, Petrini JH, (2009) The mre11 complex and the response to dysfunctional telomeres. Mol Cell Biol 29: 5540-5551.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5540-5551
-
-
Attwooll, C.L.1
Akpinar, M.2
Petrini, J.H.3
-
61
-
-
70350441980
-
Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2
-
Dimitrova N, de Lange T, (2009) Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2. Mol Cell Biol 29: 5552-5563.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5552-5563
-
-
Dimitrova, N.1
de Lange, T.2
-
62
-
-
84859352385
-
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
-
Hewitt G, Jurk D, Marques FD, Correia-Melo C, Hardy T, et al. (2012) Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nat Commun 3: 708.
-
(2012)
Nat Commun
, vol.3
, pp. 708
-
-
Hewitt, G.1
Jurk, D.2
Marques, F.D.3
Correia-Melo, C.4
Hardy, T.5
-
63
-
-
84859372986
-
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
-
Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, et al. (2012) Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat Cell Biol 14: 355-365.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 355-365
-
-
Fumagalli, M.1
Rossiello, F.2
Clerici, M.3
Barozzi, S.4
Cittaro, D.5
-
64
-
-
84863842252
-
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
-
Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, et al. (2012) Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J 31: 2839-2851.
-
(2012)
EMBO J
, vol.31
, pp. 2839-2851
-
-
Suram, A.1
Kaplunov, J.2
Patel, P.L.3
Ruan, H.4
Cerutti, A.5
-
65
-
-
34247601575
-
Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells
-
Honma M, Sakuraba M, Koizumi T, Takashima Y, Sakamoto H, et al. (2007) Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells. DNA Repair (Amst) 6: 781-788.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 781-788
-
-
Honma, M.1
Sakuraba, M.2
Koizumi, T.3
Takashima, Y.4
Sakamoto, H.5
-
66
-
-
16244403037
-
New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining
-
Rebuzzini P, Khoriauli L, Azzalin CM, Magnani E, Mondello C, et al. (2005) New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining. DNA Repair (Amst) 4: 546-555.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 546-555
-
-
Rebuzzini, P.1
Khoriauli, L.2
Azzalin, C.M.3
Magnani, E.4
Mondello, C.5
-
67
-
-
22044435250
-
Chromosomal aberrations induced by double strand DNA breaks
-
Varga T, Aplan PD, (2005) Chromosomal aberrations induced by double strand DNA breaks. DNA Repair (Amst) 4: 1038-1046.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 1038-1046
-
-
Varga, T.1
Aplan, P.D.2
-
68
-
-
67650726542
-
Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human tumor cell line
-
Zschenker O, Kulkarni A, Miller D, Reynolds GE, Granger-Locatelli M, et al. (2009) Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human tumor cell line. DNA Repair (Amst) 8: 886-900.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 886-900
-
-
Zschenker, O.1
Kulkarni, A.2
Miller, D.3
Reynolds, G.E.4
Granger-Locatelli, M.5
-
69
-
-
0034490072
-
The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line
-
Fouladi B, Miller D, Sabatier L, Murnane JP, (2000) The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line. Neoplasia 2: 540-554.
-
(2000)
Neoplasia
, vol.2
, pp. 540-554
-
-
Fouladi, B.1
Miller, D.2
Sabatier, L.3
Murnane, J.P.4
-
70
-
-
17144410403
-
The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line
-
Sabatier L, Ricoul M, Pottier G, Murnane JP, (2005) The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line. Mol Cancer Res 3: 139-150.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 139-150
-
-
Sabatier, L.1
Ricoul, M.2
Pottier, G.3
Murnane, J.P.4
-
71
-
-
75149134005
-
The effect of telomere proximity on telomere position effect, chromosome healing and sensitivity to DNA double-strand breaks in a human tumor cell line
-
Kulkarni A, Zschenker O, Reynolds G, Miller D, Murnane JP, (2010) The effect of telomere proximity on telomere position effect, chromosome healing and sensitivity to DNA double-strand breaks in a human tumor cell line. Mol Cell Biol 30: 578-589.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 578-589
-
-
Kulkarni, A.1
Zschenker, O.2
Reynolds, G.3
Miller, D.4
Murnane, J.P.5
-
72
-
-
0036867444
-
Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
-
Koering CE, Pollice A, Zibella MP, Bauwens S, Puisieux A, et al. (2002) Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity. EMBO Rep 3: 1055-1061.
-
(2002)
EMBO Rep
, vol.3
, pp. 1055-1061
-
-
Koering, C.E.1
Pollice, A.2
Zibella, M.P.3
Bauwens, S.4
Puisieux, A.5
-
73
-
-
0035874977
-
Telomere position effect in human cells
-
Baur JA, Zou Y, Shay JW, Wright WE, (2001) Telomere position effect in human cells. Science 292: 2075-2077.
-
(2001)
Science
, vol.292
, pp. 2075-2077
-
-
Baur, J.A.1
Zou, Y.2
Shay, J.W.3
Wright, W.E.4
-
74
-
-
77950462986
-
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
-
Simsek D, Jasin M, (2010) Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation. Nat Struct Mol Biol 17: 410-416.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 410-416
-
-
Simsek, D.1
Jasin, M.2
-
75
-
-
30444458875
-
A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair
-
Weinstock DM, Elliott B, Jasin M, (2006) A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair. Blood 107: 777-780.
-
(2006)
Blood
, vol.107
, pp. 777-780
-
-
Weinstock, D.M.1
Elliott, B.2
Jasin, M.3
-
76
-
-
70349472553
-
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair
-
Williams RS, Dodson GE, Limbo O, Yamada Y, Williams JS, et al. (2009) Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell 139: 87-99.
-
(2009)
Cell
, vol.139
, pp. 87-99
-
-
Williams, R.S.1
Dodson, G.E.2
Limbo, O.3
Yamada, Y.4
Williams, J.S.5
-
77
-
-
84871192059
-
Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining
-
Grabarz A, Barascu A, Guirouilh-Barbat J, Lopez BS, (2012) Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining. Am J Cancer Res 2: 249-268.
-
(2012)
Am J Cancer Res
, vol.2
, pp. 249-268
-
-
Grabarz, A.1
Barascu, A.2
Guirouilh-Barbat, J.3
Lopez, B.S.4
-
78
-
-
78649707827
-
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
-
doi:10.1371/journal.pgen.1001194
-
Bennardo N, Stark JM, (2010) ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet 6: e1001194 doi:10.1371/journal.pgen.1001194.
-
(2010)
PLoS Genet
, vol.6
-
-
Bennardo, N.1
Stark, J.M.2
-
79
-
-
77953837463
-
Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange
-
White JS, Choi S, Bakkenist CJ, (2010) Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange. Sci Signal 3: ra44.
-
(2010)
Sci Signal
, vol.3
-
-
White, J.S.1
Choi, S.2
Bakkenist, C.J.3
-
80
-
-
84866445314
-
Loss of ATM kinase activity leads to embryonic lethality in mice
-
Daniel JA, Pellegrini M, Lee BS, Guo Z, Filsuf D, et al. (2012) Loss of ATM kinase activity leads to embryonic lethality in mice. J Cell Biol 198: 295-304.
-
(2012)
J Cell Biol
, vol.198
, pp. 295-304
-
-
Daniel, J.A.1
Pellegrini, M.2
Lee, B.S.3
Guo, Z.4
Filsuf, D.5
-
81
-
-
84866459934
-
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice
-
Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, et al. (2012) Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. J Cell Biol 198: 305-313.
-
(2012)
J Cell Biol
, vol.198
, pp. 305-313
-
-
Yamamoto, K.1
Wang, Y.2
Jiang, W.3
Liu, X.4
Dubois, R.L.5
-
82
-
-
67749147223
-
Modeling ATM mutant proteins from missense changes confirms retained kinase activity
-
Barone G, Groom A, Reiman A, Srinivasan V, Byrd PJ, et al. (2009) Modeling ATM mutant proteins from missense changes confirms retained kinase activity. Hum Mutat 30: 1222-1230.
-
(2009)
Hum Mutat
, vol.30
, pp. 1222-1230
-
-
Barone, G.1
Groom, A.2
Reiman, A.3
Srinivasan, V.4
Byrd, P.J.5
-
83
-
-
77958489008
-
Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors
-
Choi S, Gamper AM, White JS, Bakkenist CJ, (2010) Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors. Cell Cycle 9: 4052-4057.
-
(2010)
Cell Cycle
, vol.9
, pp. 4052-4057
-
-
Choi, S.1
Gamper, A.M.2
White, J.S.3
Bakkenist, C.J.4
-
84
-
-
73349098442
-
Limiting the persistence of a chromosome break diminishes its mutagenic potential
-
doi:10.1371/journal.pgen.1000683
-
Bennardo N, Gunn A, Cheng A, Hasty P, Stark JM, (2009) Limiting the persistence of a chromosome break diminishes its mutagenic potential. PLoS Genet 5: e1000683 doi:10.1371/journal.pgen.1000683.
-
(2009)
PLoS Genet
, vol.5
-
-
Bennardo, N.1
Gunn, A.2
Cheng, A.3
Hasty, P.4
Stark, J.M.5
-
85
-
-
84864342422
-
Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cells
-
Shahar OD, Ram EV, Shimshoni E, Hareli S, Meshorer E, et al. (2012) Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cells. Oncogene 31: 3495-3504.
-
(2012)
Oncogene
, vol.31
, pp. 3495-3504
-
-
Shahar, O.D.1
Ram, E.V.2
Shimshoni, E.3
Hareli, S.4
Meshorer, E.5
-
86
-
-
78651595537
-
Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS
-
Kanikarla-Marie P, Ronald S, De Benedetti A, (2011) Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells- implications from repressive chromatin organization and the role of ARTEMIS. BMC Res Notes 4: 13.
-
(2011)
BMC Res Notes
, vol.4
, pp. 13
-
-
Kanikarla-Marie, P.1
Ronald, S.2
De Benedetti, A.3
-
87
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, et al. (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 31: 167-177.
-
(2008)
Mol Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
-
88
-
-
77955419733
-
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
-
Rai R, Zheng H, He H, Luo Y, Multani A, et al. (2010) The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J 29: 2598-2610.
-
(2010)
EMBO J
, vol.29
, pp. 2598-2610
-
-
Rai, R.1
Zheng, H.2
He, H.3
Luo, Y.4
Multani, A.5
-
89
-
-
0036272490
-
Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells
-
Lo AWI, Sprung CN, Fouladi B, Pedram M, Sabatier L, et al. (2002) Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. Mol Cell Biol 22: 4836-4850.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4836-4850
-
-
Lo, A.W.I.1
Sprung, C.N.2
Fouladi, B.3
Pedram, M.4
Sabatier, L.5
-
90
-
-
34948816005
-
The nature of telomere fusion and a definition of the critical telomere length in human cells
-
Capper R, Britt-Compton B, Tankimanova M, Rowson J, Letsolo B, et al. (2007) The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev 21: 2495-2508.
-
(2007)
Genes Dev
, vol.21
, pp. 2495-2508
-
-
Capper, R.1
Britt-Compton, B.2
Tankimanova, M.3
Rowson, J.4
Letsolo, B.5
-
91
-
-
84865542465
-
Telomere fusions in early human breast carcinoma
-
Tanaka H, Abe S, Huda N, Tu L, Beam MJ, et al. (2012) Telomere fusions in early human breast carcinoma. Proc Natl Acad Sci U S A 109: 14098-14103.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 14098-14103
-
-
Tanaka, H.1
Abe, S.2
Huda, N.3
Tu, L.4
Beam, M.J.5
-
92
-
-
84865364870
-
Playing the end game: DNA double-strand break repair pathway choice
-
Chapman JR, Taylor MR, Boulton SJ, (2012) Playing the end game: DNA double-strand break repair pathway choice. Mol Cell 47: 497-510.
-
(2012)
Mol Cell
, vol.47
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.2
Boulton, S.J.3
-
93
-
-
0036858415
-
DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
-
Lo AWI, Sabatier L, Fouladi B, Pottier G, Ricoul M, et al. (2002) DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 6: 531-538.
-
(2002)
Neoplasia
, vol.6
, pp. 531-538
-
-
Lo, A.W.I.1
Sabatier, L.2
Fouladi, B.3
Pottier, G.4
Ricoul, M.5
-
94
-
-
0035940501
-
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors
-
Gisselsson D, Jonson T, Petersen A, Strombeck B, Dal Cin P, et al. (2001) Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98: 12683-12688.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12683-12688
-
-
Gisselsson, D.1
Jonson, T.2
Petersen, A.3
Strombeck, B.4
Dal Cin, P.5
-
95
-
-
24344442909
-
Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication
-
Linardopoulou EV, Williams EM, Fan Y, Friedman C, Young JM, et al. (2005) Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication. Nature 437: 94-100.
-
(2005)
Nature
, vol.437
, pp. 94-100
-
-
Linardopoulou, E.V.1
Williams, E.M.2
Fan, Y.3
Friedman, C.4
Young, J.M.5
-
96
-
-
0035934003
-
Loss of subtelomeric sequence associated with a terminal inversion duplication of the short arm of chromosome 4
-
Cotter PD, Kaffe S, Li L, Gershin IF, Hirschhorn K, (2001) Loss of subtelomeric sequence associated with a terminal inversion duplication of the short arm of chromosome 4. Am J Med Genet 102: 76-80.
-
(2001)
Am J Med Genet
, vol.102
, pp. 76-80
-
-
Cotter, P.D.1
Kaffe, S.2
Li, L.3
Gershin, I.F.4
Hirschhorn, K.5
-
97
-
-
0029021347
-
Four new cases of inverted terminal duplication: a modified hypothesis of mechanism of origin
-
Hoo JJ, Chao M, Szego K, Rauer M, Echiverri SC, et al. (1995) Four new cases of inverted terminal duplication: a modified hypothesis of mechanism of origin. Am J Med Genet 58: 299-304.
-
(1995)
Am J Med Genet
, vol.58
, pp. 299-304
-
-
Hoo, J.J.1
Chao, M.2
Szego, K.3
Rauer, M.4
Echiverri, S.C.5
-
98
-
-
33845265870
-
A new genomic mechanism leading to cri-du-chat syndrome
-
South ST, Swensen JJ, Maxwell T, Rope A, Brothman AR, et al. (2006) A new genomic mechanism leading to cri-du-chat syndrome. Am J Med Genet A 140: 2714-2720.
-
(2006)
Am J Med Genet A
, vol.140
, pp. 2714-2720
-
-
South, S.T.1
Swensen, J.J.2
Maxwell, T.3
Rope, A.4
Brothman, A.R.5
-
99
-
-
77955710069
-
Telomere capture as a frequent mechanism for stabilization of the terminal chromosomal deletion associated with inverted duplication
-
Yu S, Graf WD, (2010) Telomere capture as a frequent mechanism for stabilization of the terminal chromosomal deletion associated with inverted duplication. Cytogenet Genome Res 129: 265-274.
-
(2010)
Cytogenet Genome Res
, vol.129
, pp. 265-274
-
-
Yu, S.1
Graf, W.D.2
-
100
-
-
66549096195
-
Inverted duplications deletions: underdiagnosed rearrangements??
-
Zuffardi O, Bonaglia M, Ciccone R, Giorda R, (2009) Inverted duplications deletions: underdiagnosed rearrangements?? Clin Genet 75: 505-513.
-
(2009)
Clin Genet
, vol.75
, pp. 505-513
-
-
Zuffardi, O.1
Bonaglia, M.2
Ciccone, R.3
Giorda, R.4
-
101
-
-
0020677746
-
Identity of some human bladder cancer cell lines
-
O'Toole CM, Povey S, Hepburn P, Franks LM, (1983) Identity of some human bladder cancer cell lines. Nature 301: 429-430.
-
(1983)
Nature
, vol.301
, pp. 429-430
-
-
O'Toole, C.M.1
Povey, S.2
Hepburn, P.3
Franks, L.M.4
-
102
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, et al. (2004) Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res 64: 9152-9159.
-
(2004)
Cancer Res
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
-
103
-
-
48549084245
-
ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells
-
Stohr BA, Blackburn EH, (2008) ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells. Cancer Res 68: 5309-5317.
-
(2008)
Cancer Res
, vol.68
, pp. 5309-5317
-
-
Stohr, B.A.1
Blackburn, E.H.2
-
104
-
-
46649105250
-
Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells
-
Gao Q, Reynolds GE, Wilcox A, Miller D, Cheung P, et al. (2008) Telomerase-dependent and-independent chromosome healing in mouse embryonic stem cells. DNA Repair (Amst) 7: 1233-1249.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 1233-1249
-
-
Gao, Q.1
Reynolds, G.E.2
Wilcox, A.3
Miller, D.4
Cheung, P.5
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