Unrepaired clustered DNA lesions induce chromosome breakage in human cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 20, 2011, Pages 8293-8298

  Asaithamby, Aroumougame ^a   Hu, Burong ^a   Chen, David J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

53BP1; Heterochromatin; High charge and energy particles; High linear energy transfer; Ionizing radiation induced foci

Indexed keywords

DNA; HYDROGEN PEROXIDE; IRON; OXYGEN; SILICON;

ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL SURVIVAL; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FIBROBLAST; GAMMA IRRADIATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOSIS; PRIORITY JOURNAL; RADIATION DOSE;

CELL CYCLE; CELL DIVISION; CELLS, CULTURED; CHROMOSOME BREAKAGE; DNA DAMAGE; DNA REPAIR; FIBROBLASTS; G2 PHASE; HUMANS; TISSUE DISTRIBUTION;

EID: 79957686784     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016045108     Document Type: Article

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