-
1
-
-
72049089840
-
Cellular radiosensitivity: how much better do we understand it?
-
Jeggo P., Lavin M.F. Cellular radiosensitivity: how much better do we understand it?. Int. J. Radiat. Biol. 2009, 85:1061-1081.
-
(2009)
Int. J. Radiat. Biol.
, vol.85
, pp. 1061-1081
-
-
Jeggo, P.1
Lavin, M.F.2
-
2
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan M.E., Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 2010, 11:196-207.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
3
-
-
35348821296
-
A backup DNA repair pathway moves to the forefront
-
Nussenzweig A., Nussenzweig M.C. A backup DNA repair pathway moves to the forefront. Cell 2007, 131:223-225.
-
(2007)
Cell
, vol.131
, pp. 223-225
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
4
-
-
68249150701
-
Mre11: roles in DNA repair beyond homologous recombination
-
Zha S., Boboila C., Alt F.W. Mre11: roles in DNA repair beyond homologous recombination. Nat. Struct. Mol. Biol. 2009, 16:798-800.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 798-800
-
-
Zha, S.1
Boboila, C.2
Alt, F.W.3
-
5
-
-
2942525595
-
Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells
-
Guirouilh-Barbat J., Huck S., Bertrand P., Pirzio L., Desmaze C., Sabatier L., Lopez B.S. Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells. Mol. Cell 2004, 14:611-623.
-
(2004)
Mol. Cell
, vol.14
, pp. 611-623
-
-
Guirouilh-Barbat, J.1
Huck, S.2
Bertrand, P.3
Pirzio, L.4
Desmaze, C.5
Sabatier, L.6
Lopez, B.S.7
-
6
-
-
68249146431
-
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
-
Xie A., Kwok A., Scully R. Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat. Struct. Mol. Biol. 2009, 16:814-818.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 814-818
-
-
Xie, A.1
Kwok, A.2
Scully, R.3
-
7
-
-
0037188898
-
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations
-
Zhu C., Mills K.D., Fergusion D.O., Lee C., Manis J., Fleming J., Gao Y., Morton C.C., Alt F.W. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell 2002, 109:811-821.
-
(2002)
Cell
, vol.109
, pp. 811-821
-
-
Zhu, C.1
Mills, K.D.2
Fergusion, D.O.3
Lee, C.4
Manis, J.5
Fleming, J.6
Gao, Y.7
Morton, C.C.8
Alt, F.W.9
-
8
-
-
38049187905
-
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
-
Guirouilh-Barbat J., Rass E., Plo I., Bertrand P., Lopez B.S. Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:20902-20907.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 20902-20907
-
-
Guirouilh-Barbat, J.1
Rass, E.2
Plo, I.3
Bertrand, P.4
Lopez, B.S.5
-
9
-
-
34547589577
-
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70
-
Weinstock D.M., Brunet E., Jasin M. Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat. Cell Biol. 2007, 9:978-981.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 978-981
-
-
Weinstock, D.M.1
Brunet, E.2
Jasin, M.3
-
10
-
-
77950462986
-
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
-
Simsek D., Jasin M. Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation. Nat. Struct. Mol. Biol. 2010, 17:410-416.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 410-416
-
-
Simsek, D.1
Jasin, M.2
-
11
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
Yan C.T., Boboila C., Souza E.K., Franco S., Hickernell T.R., Murphy M., Gumaste S., Geyer M., Zarrin A.A., Manis J.P., Rajewsky K., Alt F.W. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 2007, 449:478-482.
-
(2007)
Nature
, vol.449
, pp. 478-482
-
-
Yan, C.T.1
Boboila, C.2
Souza, E.K.3
Franco, S.4
Hickernell, T.R.5
Murphy, M.6
Gumaste, S.7
Geyer, M.8
Zarrin, A.A.9
Manis, J.P.10
Rajewsky, K.11
Alt, F.W.12
-
12
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo N., Cheng A., Huang N., Stark J.M. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 2008, 4:e1000110.
-
(2008)
PLoS Genet.
, vol.4
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
13
-
-
68249138694
-
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
-
Rass E., Grabarz A., Plo I., Gautier J., Bertrand P., Lopez B.S. Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells. Nat. Struct. Mol. Biol. 2009, 16:819-824.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 819-824
-
-
Rass, E.1
Grabarz, A.2
Plo, I.3
Gautier, J.4
Bertrand, P.5
Lopez, B.S.6
-
14
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
-
(2008)
Mol. Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
15
-
-
39249083653
-
Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells
-
Kato T.A., Okayasu R., Bedford J.S. Comparison of the induction and disappearance of DNA double strand breaks and gamma-H2AX foci after irradiation of chromosomes in G1-phase or in condensed metaphase cells. Mutat. Res. 2008, 639:108-112.
-
(2008)
Mutat. Res.
, vol.639
, pp. 108-112
-
-
Kato, T.A.1
Okayasu, R.2
Bedford, J.S.3
-
18
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W., de Lange T. How shelterin protects mammalian telomeres. Annu. Rev. Genet. 2008, 42:301-334.
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
19
-
-
33746425690
-
Telomere-related genome instability in cancer
-
De Lange T. Telomere-related genome instability in cancer. Cold Spring Harb. Symp. Quant. Biol. 2005, 70:197-204.
-
(2005)
Cold Spring Harb. Symp. Quant. Biol.
, vol.70
, pp. 197-204
-
-
De Lange, T.1
-
20
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d' Adda di Fagagna F.d.A.d., Reaper P.M., Clay-Farrace L., Fiegler H., Carr P., von Zglinicki T., Saretzki G., Carter N.P., Jackson S.P. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003, 426:194-198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d' Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
21
-
-
69949125332
-
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
-
Nakamura A.J., Chiang Y.J., Hathcock K.S., Horikawa I., Sedelnikova O.A., Hodes R.J., Bonner W.M. Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics Chromatin 2008, 1:6.
-
(2008)
Epigenetics Chromatin
, vol.1
, pp. 6
-
-
Nakamura, A.J.1
Chiang, Y.J.2
Hathcock, K.S.3
Horikawa, I.4
Sedelnikova, O.A.5
Hodes, R.J.6
Bonner, W.M.7
-
22
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 1992, 11:1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
23
-
-
0037427471
-
Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast
-
Ricchetti M., Dujon B., Fairhead C. Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast. J. Mol. Biol. 2003, 328:847-862.
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 847-862
-
-
Ricchetti, M.1
Dujon, B.2
Fairhead, C.3
-
24
-
-
67650726542
-
Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human tumor cell line
-
Zschenker O., Kulkarni A., Miller D., Reynolds G.E., Granger-Locatelli M., Pottier G., Sabatier L., Murnane J.P. Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human tumor cell line. DNA Repair 2009, 8:886-900.
-
(2009)
DNA Repair
, vol.8
, pp. 886-900
-
-
Zschenker, O.1
Kulkarni, A.2
Miller, D.3
Reynolds, G.E.4
Granger-Locatelli, M.5
Pottier, G.6
Sabatier, L.7
Murnane, J.P.8
-
25
-
-
46649105250
-
Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells
-
Gao Q., Reynolds G.E., Wilcox A., Miller D., Cheung P., Artandi S.E., Murnane J.P. Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells. DNA Repair 2008, 7:1233-1249.
-
(2008)
DNA Repair
, vol.7
, pp. 1233-1249
-
-
Gao, Q.1
Reynolds, G.E.2
Wilcox, A.3
Miller, D.4
Cheung, P.5
Artandi, S.E.6
Murnane, J.P.7
-
26
-
-
0036272490
-
Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells
-
Lo A.W.I., Sprung C.N., Fouladi B., Pedram M., Sabatier L., Ricoul M., Reynolds G.E., Murnane J.P. Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. Mol. Cell Biol. 2002, 22:4836-4850.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 4836-4850
-
-
Lo, A.W.I.1
Sprung, C.N.2
Fouladi, B.3
Pedram, M.4
Sabatier, L.5
Ricoul, M.6
Reynolds, G.E.7
Murnane, J.P.8
-
27
-
-
0035940501
-
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors
-
Gisselsson D., Jonson T., Petersen A., Strombeck B., Dal Cin P., Hoglund M., Mitelman F., Mertens F., Mandahl N. Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:12683-12688.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 12683-12688
-
-
Gisselsson, D.1
Jonson, T.2
Petersen, A.3
Strombeck, B.4
Dal Cin, P.5
Hoglund, M.6
Mitelman, F.7
Mertens, F.8
Mandahl, N.9
-
28
-
-
77951976271
-
Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells
-
Nakamura A.J., Redon C.E., Bonner W.M., Sedelnikova O.A. Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells. Aging (Albany NY) 2009, 1:212-218.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 212-218
-
-
Nakamura, A.J.1
Redon, C.E.2
Bonner, W.M.3
Sedelnikova, O.A.4
-
29
-
-
33747882534
-
Telomeres and chromosome instability
-
Murnane J.P. Telomeres and chromosome instability. DNA Repair (Amst.) 2006, 5:1082-1092.
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 1082-1092
-
-
Murnane, J.P.1
-
30
-
-
17144410403
-
The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line
-
Sabatier L., Ricoul M., Pottier G., Murnane J.P. The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line. Mol. Cancer Res. 2005, 3:139-150.
-
(2005)
Mol. Cancer Res.
, vol.3
, pp. 139-150
-
-
Sabatier, L.1
Ricoul, M.2
Pottier, G.3
Murnane, J.P.4
-
31
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi S.E., Chang S., Lee S.-L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 2000, 406:641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.-L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
32
-
-
75149134005
-
The effect of telomere proximity on telomere position effect, chromosome healing and sensitivity to DNA double-strand breaks in a human tumor cell line
-
Kulkarni A., Zschenker O., Reynolds G., Miller D., Murnane J.P. The effect of telomere proximity on telomere position effect, chromosome healing and sensitivity to DNA double-strand breaks in a human tumor cell line. Mol. Cell Biol. 2010, 30:578-589.
-
(2010)
Mol. Cell Biol.
, vol.30
, pp. 578-589
-
-
Kulkarni, A.1
Zschenker, O.2
Reynolds, G.3
Miller, D.4
Murnane, J.P.5
-
33
-
-
34247601575
-
Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells
-
Honma M., Sakuraba M., Koizumi T., Takashima Y., Sakamoto H., Hayashi M. Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells. DNA Repair (Amst.) 2007, 6:781-788.
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 781-788
-
-
Honma, M.1
Sakuraba, M.2
Koizumi, T.3
Takashima, Y.4
Sakamoto, H.5
Hayashi, M.6
-
34
-
-
22044435250
-
Chromosomal aberrations induced by double strand DNA breaks
-
Varga T., Aplan P.D. Chromosomal aberrations induced by double strand DNA breaks. DNA Repair (Amst.) 2005, 4:1038-1046.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 1038-1046
-
-
Varga, T.1
Aplan, P.D.2
-
35
-
-
16244403037
-
New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining
-
Rebuzzini P., Khoriauli L., Azzalin C.M., Magnani E., Mondello C., Giulotto E. New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining. DNA Repair (Amst.) 2005, 4:546-555.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 546-555
-
-
Rebuzzini, P.1
Khoriauli, L.2
Azzalin, C.M.3
Magnani, E.4
Mondello, C.5
Giulotto, E.6
-
36
-
-
0034621854
-
Frequent chromosomal translocations induced by DNA double-strand breaks
-
Richardson C., Jasin M. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 2000, 405:697-700.
-
(2000)
Nature
, vol.405
, pp. 697-700
-
-
Richardson, C.1
Jasin, M.2
-
37
-
-
0032535036
-
Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations
-
Richardson C., Moynahan M.E., Jasin M. Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev. 1998, 12:3831-3842.
-
(1998)
Genes Dev.
, vol.12
, pp. 3831-3842
-
-
Richardson, C.1
Moynahan, M.E.2
Jasin, M.3
-
38
-
-
0034490072
-
The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line
-
Fouladi B., Miller D., Sabatier L., Murnane J.P. The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line. Neoplasia 2000, 2:540-554.
-
(2000)
Neoplasia
, vol.2
, pp. 540-554
-
-
Fouladi, B.1
Miller, D.2
Sabatier, L.3
Murnane, J.P.4
-
39
-
-
0035874894
-
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation
-
Moynahan M.E., Cui T.Y., Jasin M. Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res. 2001, 61:4842-4850.
-
(2001)
Cancer Res.
, vol.61
, pp. 4842-4850
-
-
Moynahan, M.E.1
Cui, T.Y.2
Jasin, M.3
-
40
-
-
0033535987
-
Chromosome healing in mouse embryonic stem cells
-
Sprung C.N., Reynolds G.E., Jasin M., Murnane J.P. Chromosome healing in mouse embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:6781-6786.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6781-6786
-
-
Sprung, C.N.1
Reynolds, G.E.2
Jasin, M.3
Murnane, J.P.4
-
41
-
-
0020677746
-
Identity of some human bladder cancer cell lines
-
O'Toole C.M., Povey S., Hepburn P., Franks L.M. Identity of some human bladder cancer cell lines. Nature 1983, 301:429-430.
-
(1983)
Nature
, vol.301
, pp. 429-430
-
-
O'Toole, C.M.1
Povey, S.2
Hepburn, P.3
Franks, L.M.4
-
42
-
-
0036858415
-
DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
-
Lo A.W.I., Sabatier L., Fouladi B., Pottier G., Ricoul M., Murnane J.P. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 2002, 6:531-538.
-
(2002)
Neoplasia
, vol.6
, pp. 531-538
-
-
Lo, A.W.I.1
Sabatier, L.2
Fouladi, B.3
Pottier, G.4
Ricoul, M.5
Murnane, J.P.6
-
43
-
-
0034461607
-
Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells
-
Richardson C., Jasin M. Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol. Cell Biol. 2000, 20:9068-9075.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 9068-9075
-
-
Richardson, C.1
Jasin, M.2
-
44
-
-
0034951142
-
Double-strand-break-induced homologous recombination in mammalian cells
-
Johnson R.D., Jasin M. Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc. Trans. 2001, 29:196-201.
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 196-201
-
-
Johnson, R.D.1
Jasin, M.2
-
45
-
-
11244251788
-
Genetic interactions between BLM and DNA ligase IV in human cells
-
So S., Adachi N., Lieber M.R., Koyama H. Genetic interactions between BLM and DNA ligase IV in human cells. J. Biol. Chem. 2004, 279:55433-55442.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 55433-55442
-
-
So, S.1
Adachi, N.2
Lieber, M.R.3
Koyama, H.4
-
46
-
-
39449129496
-
The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends
-
Aniukwu J., Glickman M.S., Shuman S. The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends. Genes Dev. 2008, 22:512-527.
-
(2008)
Genes Dev.
, vol.22
, pp. 512-527
-
-
Aniukwu, J.1
Glickman, M.S.2
Shuman, S.3
-
47
-
-
77649225150
-
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells
-
Fattah F., Lee E.H., Weisensel N., Wang Y., Lichter N., Hendrickson E.A. Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells. PLoS Genet. 2010, 6:e1000855.
-
(2010)
PLoS Genet.
, vol.6
-
-
Fattah, F.1
Lee, E.H.2
Weisensel, N.3
Wang, Y.4
Lichter, N.5
Hendrickson, E.A.6
-
48
-
-
78649707827
-
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
-
Bennardo N., Stark J.M. ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet. 2010, 6:e1001194.
-
(2010)
PLoS Genet.
, vol.6
-
-
Bennardo, N.1
Stark, J.M.2
-
49
-
-
32944459979
-
Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining
-
Wang H.C., Chou W.C., Shieh S.Y., Shen C.Y. Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining. Cancer Res. 2006, 66:1391-1400.
-
(2006)
Cancer Res.
, vol.66
, pp. 1391-1400
-
-
Wang, H.C.1
Chou, W.C.2
Shieh, S.Y.3
Shen, C.Y.4
-
50
-
-
34948816005
-
The nature of telomere fusion and a definition of the critical telomere length in human cells
-
Capper R., Britt-Compton B., Tankimanova M., Rowson J., Letsolo B., Man S., Haughton M., Baird D.M. The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev. 2007, 21:2495-2508.
-
(2007)
Genes Dev.
, vol.21
, pp. 2495-2508
-
-
Capper, R.1
Britt-Compton, B.2
Tankimanova, M.3
Rowson, J.4
Letsolo, B.5
Man, S.6
Haughton, M.7
Baird, D.M.8
-
51
-
-
77955419733
-
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
-
Rai R., Zheng H., He H., Luo Y., Multani A., Carpenter P.B., Chang S. The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J. 2010, 29:2598-2610.
-
(2010)
EMBO J.
, vol.29
, pp. 2598-2610
-
-
Rai, R.1
Zheng, H.2
He, H.3
Luo, Y.4
Multani, A.5
Carpenter, P.B.6
Chang, S.7
-
52
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
Denchi E.L., de Lange T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 2007, 448:1068-1071.
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
de Lange, T.2
-
53
-
-
0033961281
-
Control of human telomere length by TRF1 and TRF2
-
Smogorzewska A., van Steensel B., Bianchi A., Oelmann S., Schaefer M.R., Schnapp G., de Lange T. Control of human telomere length by TRF1 and TRF2. Mol. Cell Biol. 2000, 20:1659-1668.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1659-1668
-
-
Smogorzewska, A.1
van Steensel, B.2
Bianchi, A.3
Oelmann, S.4
Schaefer, M.R.5
Schnapp, G.6
de Lange, T.7
-
54
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusions
-
van Steensel B., Smogorzewska A., de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell 1998, 92:401-413.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
van Steensel, B.1
Smogorzewska, A.2
de Lange, T.3
-
55
-
-
19344374569
-
The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
-
Karlseder J., Hoke K., Mirzoeva O.K., Bakkenist C., Kastan M.B., Petrini J.H., de Lange T. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. PLoS Biol. 2004, 2:E240.
-
(2004)
PLoS Biol.
, vol.2
-
-
Karlseder, J.1
Hoke, K.2
Mirzoeva, O.K.3
Bakkenist, C.4
Kastan, M.B.5
Petrini, J.H.6
de Lange, T.7
-
56
-
-
0342561644
-
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
-
Zhu X.-D., Kuster B., Mann M., Petrini J.H.J., de Lange T. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat. Genet. 2000, 25:347-352.
-
(2000)
Nat. Genet.
, vol.25
, pp. 347-352
-
-
Zhu, X.-D.1
Kuster, B.2
Mann, M.3
Petrini, J.H.J.4
de Lange, T.5
-
57
-
-
27644578165
-
A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint
-
Michelson R.J., Rosenstein S., Weinert T. A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint. Genes Dev. 2005, 19:2546-2559.
-
(2005)
Genes Dev.
, vol.19
, pp. 2546-2559
-
-
Michelson, R.J.1
Rosenstein, S.2
Weinert, T.3
-
58
-
-
0347988045
-
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
-
Garcia-Cao M., O'Sullivan R., Peters A.H., Jenuwein T., Blasco M.A. Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat. Genet. 2004, 36:94-99.
-
(2004)
Nat. Genet.
, vol.36
, pp. 94-99
-
-
Garcia-Cao, M.1
O'Sullivan, R.2
Peters, A.H.3
Jenuwein, T.4
Blasco, M.A.5
-
59
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo S., Jaco I., Fraga M.F., Chen T., Li E., Esteller M., Blasco M.A. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat. Cell Biol. 2006, 8:416-424.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
60
-
-
79955078702
-
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks
-
Zha S., Guo C., Boboila C., Oksenych V., Cheng H.L., Zhang Y., Wesemann D.R., Yuen G., Patel H., Goff P.H., Dubois R.L., Alt F.W. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature 2010.
-
(2010)
Nature
-
-
Zha, S.1
Guo, C.2
Boboila, C.3
Oksenych, V.4
Cheng, H.L.5
Zhang, Y.6
Wesemann, D.R.7
Yuen, G.8
Patel, H.9
Goff, P.H.10
Dubois, R.L.11
Alt, F.W.12
-
61
-
-
68949149732
-
Multiple roles for MRE11 at uncapped telomeres
-
Deng Y., Guo X., Ferguson D.O., Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature 2009, 460:914-918.
-
(2009)
Nature
, vol.460
, pp. 914-918
-
-
Deng, Y.1
Guo, X.2
Ferguson, D.O.3
Chang, S.4
-
62
-
-
58249109501
-
Functional dissection of human and mouse POT1 proteins
-
Palm W., Hockemeyer D., Kibe T., de Lange T. Functional dissection of human and mouse POT1 proteins. Mol. Cell Biol. 2009, 29:471-482.
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 471-482
-
-
Palm, W.1
Hockemeyer, D.2
Kibe, T.3
de Lange, T.4
-
63
-
-
33745713451
-
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
-
Wu L., Multani A.S., He H., Cosme-Blanco W., Deng Y., Deng J.M., Bachilo O., Pathak S., Tahara H., Bailey S.M., Behringer R.R., Chang S. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell 2006, 126:49-62.
-
(2006)
Cell
, vol.126
, pp. 49-62
-
-
Wu, L.1
Multani, A.S.2
He, H.3
Cosme-Blanco, W.4
Deng, Y.5
Deng, J.M.6
Bachilo, O.7
Pathak, S.8
Tahara, H.9
Bailey, S.M.10
Behringer, R.R.11
Chang, S.12
-
64
-
-
34247600494
-
A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends
-
Bae N.S., Baumann P. A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends. Mol. Cell 2007, 26:323-334.
-
(2007)
Mol. Cell
, vol.26
, pp. 323-334
-
-
Bae, N.S.1
Baumann, P.2
-
65
-
-
77953161582
-
Telomere loss as a mechanism for chromosomal instability in human cancer
-
Murnane J.P. Telomere loss as a mechanism for chromosomal instability in human cancer. Cancer Res. 2010, 70:4255-4259.
-
(2010)
Cancer Res.
, vol.70
, pp. 4255-4259
-
-
Murnane, J.P.1
-
66
-
-
0002011265
-
Gene amplification in human cancers: biological and clinical significance
-
McGraw-Hill, New York, B. Vogelstein, K.W. Kinzler (Eds.)
-
Brodeur G.M., Hogarety M.D. Gene amplification in human cancers: biological and clinical significance. The Genetic Basis of Human Cancer 1998, 161-172. McGraw-Hill, New York. B. Vogelstein, K.W. Kinzler (Eds.).
-
(1998)
The Genetic Basis of Human Cancer
, pp. 161-172
-
-
Brodeur, G.M.1
Hogarety, M.D.2
-
67
-
-
0035120289
-
Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease
-
Gollin S.M. Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 2001, 23:238-253.
-
(2001)
Head Neck
, vol.23
, pp. 238-253
-
-
Gollin, S.M.1
-
68
-
-
0032823534
-
Oncogene amplification in solid tumors
-
Schwab M. Oncogene amplification in solid tumors. Sem. Cancer Biol. 1999, 9:319-325.
-
(1999)
Sem. Cancer Biol.
, vol.9
, pp. 319-325
-
-
Schwab, M.1
-
69
-
-
44349119351
-
Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study
-
Tsantoulis P.K., Kotsinas A., Sfikakis P.P., Evangelou K., Sideridou M., Levy B., Mo L., Kittas C., Wu X.R., Papavassiliou A.G., Gorgoulis V.G. Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study. Oncogene 2008, 27:3256-3264.
-
(2008)
Oncogene
, vol.27
, pp. 3256-3264
-
-
Tsantoulis, P.K.1
Kotsinas, A.2
Sfikakis, P.P.3
Evangelou, K.4
Sideridou, M.5
Levy, B.6
Mo, L.7
Kittas, C.8
Wu, X.R.9
Papavassiliou, A.G.10
Gorgoulis, V.G.11
-
70
-
-
67649635974
-
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
-
Sfeir A., Kosiyatrakul S.T., Hockemeyer D., MacRae S.L., Karlseder J., Schildkraut C.L., de Lange T. Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 2009, 138:90-103.
-
(2009)
Cell
, vol.138
, pp. 90-103
-
-
Sfeir, A.1
Kosiyatrakul, S.T.2
Hockemeyer, D.3
MacRae, S.L.4
Karlseder, J.5
Schildkraut, C.L.6
de Lange, T.7
-
71
-
-
0141645600
-
Radiation-induced genomic instability and its implications for radiation carcinogenesis
-
Huang L., Snyder A.R., Morgan W.F. Radiation-induced genomic instability and its implications for radiation carcinogenesis. Oncogene 2003, 22:5848-5854.
-
(2003)
Oncogene
, vol.22
, pp. 5848-5854
-
-
Huang, L.1
Snyder, A.R.2
Morgan, W.F.3
|