Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice

Journal of Cell Biology

Volumn 198, Issue 3, 2012, Pages 305-313

  Yamamoto, Kenta ^a,b,c   Wang, Yunyue ^a,b   Jiang, Wenxia ^a,b   Liu, Xiangyu ^a,b   Dubois, Richard L ^a,b   Lin, Chyuan Sheng ^b   Ludwig, Thomas ^a,b,f   Bakkenist, Christopher J ^d,e   Zha, Shan ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c University of Pittsburgh School of Medicine ^*  (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^f THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; KINASE DEAD ATM PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; GENETIC RECOMBINATION; GENOMIC INSTABILITY; HUMAN; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALLELES; ANIMALS; BASE SEQUENCE; CATALYSIS; CELL CYCLE PROTEINS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; EXONS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMOZYGOTE; HUMANS; LYMPHOCYTES; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MUS;

EID: 84866459934     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201204098     Document Type: Article

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