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Volumn 8, Issue 8, 2009, Pages 886-900

Increased sensitivity of subtelomeric regions to DNA double-strand breaks in a human cancer cell line

Author keywords

Chromosomal instability; Double strand break; Gross chromosomal rearrangements; Sister chromatid fusion; Telomeres

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; GANCICLOVIR;

EID: 67650726542     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.05.004     Document Type: Article
Times cited : (32)

References (71)
  • 1
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska A., and de Lange T. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73 (2004) 177-208
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 177-208
    • Smogorzewska, A.1    de Lange, T.2
  • 3
    • 0345169051 scopus 로고    scopus 로고
    • Getting to the end: telomerase access in yeast and humans
    • Vega L.R., Mateyak M.K., and Zakian V.A. Getting to the end: telomerase access in yeast and humans. Nat. Rev. Mol. Cell Biol. 4 (2003) 948-959
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 948-959
    • Vega, L.R.1    Mateyak, M.K.2    Zakian, V.A.3
  • 4
    • 0001934324 scopus 로고
    • Telomeres and aging
    • Blackburn E.H., and Greider C.W. (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor
    • Harley C.B. Telomeres and aging. In: Blackburn E.H., and Greider C.W. (Eds). Telomeres (1995), Cold Spring Harbor Laboratory Press, Cold Spring Harbor 247-263
    • (1995) Telomeres , pp. 247-263
    • Harley, C.B.1
  • 5
    • 44349136891 scopus 로고    scopus 로고
    • Telomere dysfunction and tumour suppression: the senescence connection
    • Deng Y., Chan S.S., and Chang S. Telomere dysfunction and tumour suppression: the senescence connection. Nat. Rev. Cancer 8 (2008) 450-458
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 450-458
    • Deng, Y.1    Chan, S.S.2    Chang, S.3
  • 6
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., and Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11 (1992) 1921-1929
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 7
    • 0033595174 scopus 로고    scopus 로고
    • Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process
    • Ducray C., Pommier J.-P., Martins L., Boussin F., and Sabatier L. Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process. Oncogene 18 (1999) 4211-4223
    • (1999) Oncogene , vol.18 , pp. 4211-4223
    • Ducray, C.1    Pommier, J.-P.2    Martins, L.3    Boussin, F.4    Sabatier, L.5
  • 8
    • 0029991014 scopus 로고    scopus 로고
    • Telomerase activity in human cancer
    • Shay J.W., and Wright W.E. Telomerase activity in human cancer. Curr. Opin. Oncol. 8 (1996) 66-71
    • (1996) Curr. Opin. Oncol. , vol.8 , pp. 66-71
    • Shay, J.W.1    Wright, W.E.2
  • 9
    • 41449105355 scopus 로고    scopus 로고
    • Telomere length, telomeric proteins and genomic instability during the multistep carcinogenic process
    • Raynaud C.M., Sabatier L., Philipot O., Olaussen K.A., and Soria J.C. Telomere length, telomeric proteins and genomic instability during the multistep carcinogenic process. Crit. Rev. Oncol. Hematol. 66 (2008) 99-117
    • (2008) Crit. Rev. Oncol. Hematol. , vol.66 , pp. 99-117
    • Raynaud, C.M.1    Sabatier, L.2    Philipot, O.3    Olaussen, K.A.4    Soria, J.C.5
  • 10
    • 0038392859 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres: dangerous road less travelled
    • Reddel R.R., and Bryan T.M. Alternative lengthening of telomeres: dangerous road less travelled. Lancet 361 (2003) 1840-1841
    • (2003) Lancet , vol.361 , pp. 1840-1841
    • Reddel, R.R.1    Bryan, T.M.2
  • 11
    • 33646831821 scopus 로고    scopus 로고
    • Telomeres, chromosome instability and cancer
    • Bailey S.M., and Murnane J.P. Telomeres, chromosome instability and cancer. Nucl. Acids Res. 34 (2006) 2408-2417
    • (2006) Nucl. Acids Res. , vol.34 , pp. 2408-2417
    • Bailey, S.M.1    Murnane, J.P.2
  • 12
    • 33747882534 scopus 로고    scopus 로고
    • Telomeres and chromosome instability
    • Murnane J.P. Telomeres and chromosome instability. DNA Repair (Amst) 5 (2006) 1082-1092
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1082-1092
    • Murnane, J.P.1
  • 13
    • 17144410403 scopus 로고    scopus 로고
    • The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line
    • Sabatier L., Ricoul M., Pottier G., and Murnane J.P. The loss of a single telomere can result in genomic instability involving multiple chromosomes in a human tumor cell line. Mol. Cancer Res. 3 (2005) 139-150
    • (2005) Mol. Cancer Res. , vol.3 , pp. 139-150
    • Sabatier, L.1    Ricoul, M.2    Pottier, G.3    Murnane, J.P.4
  • 14
    • 33746425690 scopus 로고    scopus 로고
    • Telomere-related genome instability in cancer
    • de Lange T. Telomere-related genome instability in cancer. Cold Spring Harb. Symp. Quant. Biol. 70 (2005) 197-204
    • (2005) Cold Spring Harb. Symp. Quant. Biol. , vol.70 , pp. 197-204
    • de Lange, T.1
  • 15
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi S.E., Chang S., Lee S.-L., Alson S., Gottlieb G.J., Chin L., and DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406 (2000) 641-645
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.-L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    DePinho, R.A.7
  • 19
    • 0642336728 scopus 로고    scopus 로고
    • Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies
    • Montgomery E., Wilentz R.E., and Argani P. Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies. Cancer Biol. Ther. 2 (2003) 248-252
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 248-252
    • Montgomery, E.1    Wilentz, R.E.2    Argani, P.3
  • 21
    • 0034490072 scopus 로고    scopus 로고
    • The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line
    • Fouladi B., Miller D., Sabatier L., and Murnane J.P. The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line. Neoplasia 2 (2000) 540-554
    • (2000) Neoplasia , vol.2 , pp. 540-554
    • Fouladi, B.1    Miller, D.2    Sabatier, L.3    Murnane, J.P.4
  • 24
    • 0036606186 scopus 로고    scopus 로고
    • Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA
    • Ivessa A.S., Zhou J.-Q., Schulz V.P., Monson E.K., and Zakian V.A. Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA. Genes Dev. 16 (2002) 1383-1396
    • (2002) Genes Dev. , vol.16 , pp. 1383-1396
    • Ivessa, A.S.1    Zhou, J.-Q.2    Schulz, V.P.3    Monson, E.K.4    Zakian, V.A.5
  • 25
    • 0037427471 scopus 로고    scopus 로고
    • Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast
    • Ricchetti M., Dujon B., and Fairhead C. Distance from the chromosome end determines the efficiency of double-strand break repair in subtelomeres of haploid yeast. J. Mol. Biol. 328 (2003) 847-862
    • (2003) J. Mol. Biol. , vol.328 , pp. 847-862
    • Ricchetti, M.1    Dujon, B.2    Fairhead, C.3
  • 26
    • 0034621854 scopus 로고    scopus 로고
    • Frequent chromosomal translocations induced by DNA double-strand breaks
    • Richardson C., and Jasin M. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 405 (2000) 697-700
    • (2000) Nature , vol.405 , pp. 697-700
    • Richardson, C.1    Jasin, M.2
  • 27
    • 0034461607 scopus 로고    scopus 로고
    • Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells
    • Richardson C., and Jasin M. Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol. Cell. Biol. 20 (2000) 9068-9075
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 9068-9075
    • Richardson, C.1    Jasin, M.2
  • 28
    • 0032535036 scopus 로고    scopus 로고
    • Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations
    • Richardson C., Moynahan M.E., and Jasin M. Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations. Genes Dev. 12 (1998) 3831-3842
    • (1998) Genes Dev. , vol.12 , pp. 3831-3842
    • Richardson, C.1    Moynahan, M.E.2    Jasin, M.3
  • 29
    • 34247601575 scopus 로고    scopus 로고
    • Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells
    • Honma M., Sakuraba M., Koizumi T., Takashima Y., Sakamoto H., and Hayashi M. Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells. DNA Repair (Amst) 6 (2007) 781-788
    • (2007) DNA Repair (Amst) , vol.6 , pp. 781-788
    • Honma, M.1    Sakuraba, M.2    Koizumi, T.3    Takashima, Y.4    Sakamoto, H.5    Hayashi, M.6
  • 30
    • 16244403037 scopus 로고    scopus 로고
    • New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining
    • Rebuzzini P., Khoriauli L., Azzalin C.M., Magnani E., Mondello C., and Giulotto E. New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining. DNA Repair (Amst) 4 (2005) 546-555
    • (2005) DNA Repair (Amst) , vol.4 , pp. 546-555
    • Rebuzzini, P.1    Khoriauli, L.2    Azzalin, C.M.3    Magnani, E.4    Mondello, C.5    Giulotto, E.6
  • 31
    • 0031032549 scopus 로고    scopus 로고
    • Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
    • Sargent R.G., Brenneman M.A., and Wilson J.H. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol. Cell. Biol. 17 (1997) 267-277
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 267-277
    • Sargent, R.G.1    Brenneman, M.A.2    Wilson, J.H.3
  • 32
    • 22044435250 scopus 로고    scopus 로고
    • Chromosomal aberrations induced by double strand DNA breaks
    • Varga T., and Aplan P.D. Chromosomal aberrations induced by double strand DNA breaks. DNA Repair (Amst) 4 (2005) 1038-1046
    • (2005) DNA Repair (Amst) , vol.4 , pp. 1038-1046
    • Varga, T.1    Aplan, P.D.2
  • 34
    • 0020677746 scopus 로고
    • Identity of some human bladder cancer cell lines
    • O'Toole C.M., Povey S., Hepburn P., and Franks L.M. Identity of some human bladder cancer cell lines. Nature 301 (1983) 429-430
    • (1983) Nature , vol.301 , pp. 429-430
    • O'Toole, C.M.1    Povey, S.2    Hepburn, P.3    Franks, L.M.4
  • 35
    • 0029020644 scopus 로고
    • The three-dimensional structure of thymidine kinase from Herpes simplex virus type 1
    • Wild K., Bohner T., Aubry A., Folkers G., and Schulz G.E. The three-dimensional structure of thymidine kinase from Herpes simplex virus type 1. FEBS 368 (1995) 289-292
    • (1995) FEBS , vol.368 , pp. 289-292
    • Wild, K.1    Bohner, T.2    Aubry, A.3    Folkers, G.4    Schulz, G.E.5
  • 36
    • 0022379386 scopus 로고
    • Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase
    • Haarr L., Marsden H.S., Preston C.M., Smiley J.R., Summers W.C., and Summers W.P. Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase. J. Virol. 56 (1985) 512-519
    • (1985) J. Virol. , vol.56 , pp. 512-519
    • Haarr, L.1    Marsden, H.S.2    Preston, C.M.3    Smiley, J.R.4    Summers, W.C.5    Summers, W.P.6
  • 37
    • 0024551693 scopus 로고
    • Effect of an amber mutation in the herpes simplex virus thymidine kinase gene on polypeptide synthesis and stability
    • Irmiere A.F., Manos M.M., Jacobson J.G., Gibbs J.S., and Coen D.M. Effect of an amber mutation in the herpes simplex virus thymidine kinase gene on polypeptide synthesis and stability. Virology 168 (1989) 210-220
    • (1989) Virology , vol.168 , pp. 210-220
    • Irmiere, A.F.1    Manos, M.M.2    Jacobson, J.G.3    Gibbs, J.S.4    Coen, D.M.5
  • 44
    • 0028557213 scopus 로고
    • Stringent sequence requirements for the formation of human telomeres
    • Hanish J.P., Yanowitz J.L., and de Lange T. Stringent sequence requirements for the formation of human telomeres. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 8861-8865
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.L.2    de Lange, T.3
  • 45
    • 33644502519 scopus 로고    scopus 로고
    • Telomere position effect and silencing of transgenes near telomeres in the mouse
    • Pedram M., Sprung C.N., Gao Q., Lo A.W.I., Reynolds G., and Murnane J.P. Telomere position effect and silencing of transgenes near telomeres in the mouse. Mol. Cell. Biol. 26 (2006) 1865-1878
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1865-1878
    • Pedram, M.1    Sprung, C.N.2    Gao, Q.3    Lo, A.W.I.4    Reynolds, G.5    Murnane, J.P.6
  • 47
    • 0033602035 scopus 로고    scopus 로고
    • Telomere dynamics in a human cancer cell line
    • Sprung C.N., Sabatier L., and Murnane J.P. Telomere dynamics in a human cancer cell line. Exp. Cell Res. 247 (1999) 29-37
    • (1999) Exp. Cell Res. , vol.247 , pp. 29-37
    • Sprung, C.N.1    Sabatier, L.2    Murnane, J.P.3
  • 48
    • 0027262360 scopus 로고
    • Selection for spontaneous null mutations in a chromosomally integrated HSV-1 thymidine kinase gene yields deletions and a mutation caused by intragenic illegitimate recombination
    • Brisebois J.J., and DuBow M.S. Selection for spontaneous null mutations in a chromosomally integrated HSV-1 thymidine kinase gene yields deletions and a mutation caused by intragenic illegitimate recombination. Mutat. Res. 287 (1993) 191-205
    • (1993) Mutat. Res. , vol.287 , pp. 191-205
    • Brisebois, J.J.1    DuBow, M.S.2
  • 49
    • 0028962972 scopus 로고
    • A new retroviral vector for detecting mutations and chromosomal instability in mammalian cells
    • Murata S., Matsuzaki T., Takai S., Yaoita H., and Noda M. A new retroviral vector for detecting mutations and chromosomal instability in mammalian cells. Muatat. Res. 334 (1995) 375-383
    • (1995) Muatat. Res. , vol.334 , pp. 375-383
    • Murata, S.1    Matsuzaki, T.2    Takai, S.3    Yaoita, H.4    Noda, M.5
  • 50
    • 0031014020 scopus 로고    scopus 로고
    • Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cells
    • Meier J.L., and Stinski M.F. Effect of a modulator deletion on transcription of the human cytomegalovirus major immediate-early genes in infected undifferentiated and differentiated cells. J. Virol. 71 (1997) 1246-1255
    • (1997) J. Virol. , vol.71 , pp. 1246-1255
    • Meier, J.L.1    Stinski, M.F.2
  • 52
    • 0036858415 scopus 로고    scopus 로고
    • DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line
    • Lo A.W.I., Sabatier L., Fouladi B., Pottier G., Ricoul M., and Murnane J.P. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 6 (2002) 531-538
    • (2002) Neoplasia , vol.6 , pp. 531-538
    • Lo, A.W.I.1    Sabatier, L.2    Fouladi, B.3    Pottier, G.4    Ricoul, M.5    Murnane, J.P.6
  • 53
    • 0036244955 scopus 로고    scopus 로고
    • The complex structure and dynamic evolution of human subtelomeres
    • Mefford H.C., and Trask B.J. The complex structure and dynamic evolution of human subtelomeres. Nat. Rev. Genet. 3 (2002) 91-102
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 91-102
    • Mefford, H.C.1    Trask, B.J.2
  • 54
    • 52149095466 scopus 로고    scopus 로고
    • Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases
    • Weinstock D.M., Brunet E., and Jasin M. Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases. J. Natl. Cancer Inst. Monogr. 2008 (2008) 20-24
    • (2008) J. Natl. Cancer Inst. Monogr. , vol.2008 , pp. 20-24
    • Weinstock, D.M.1    Brunet, E.2    Jasin, M.3
  • 55
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • Lieber M.R. The mechanism of human nonhomologous DNA end joining. J. Biol. Chem. 283 (2008) 1-5
    • (2008) J. Biol. Chem. , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 56
    • 35348821296 scopus 로고    scopus 로고
    • A backup DNA repair pathway moves to the forefront
    • Nussenzweig A., and Nussenzweig M.C. A backup DNA repair pathway moves to the forefront. Cell 131 (2007) 223-225
    • (2007) Cell , vol.131 , pp. 223-225
    • Nussenzweig, A.1    Nussenzweig, M.C.2
  • 57
    • 0037202608 scopus 로고    scopus 로고
    • Recombinational DNA repair and human disease
    • Thompson L.H., and Schild D. Recombinational DNA repair and human disease. Mutat. Res. 509 (2002) 49-78
    • (2002) Mutat. Res. , vol.509 , pp. 49-78
    • Thompson, L.H.1    Schild, D.2
  • 59
    • 38049187905 scopus 로고    scopus 로고
    • Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
    • Guirouilh-Barbat J., Rass E., Plo I., Bertrand P., and Lopez B.S. Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 20902-20907
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 20902-20907
    • Guirouilh-Barbat, J.1    Rass, E.2    Plo, I.3    Bertrand, P.4    Lopez, B.S.5
  • 60
    • 46249131123 scopus 로고    scopus 로고
    • Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
    • Bennardo N., Cheng A., Huang N., and Stark J.M. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 4 (2008) e1000110
    • (2008) PLoS Genet. , vol.4
    • Bennardo, N.1    Cheng, A.2    Huang, N.3    Stark, J.M.4
  • 61
    • 46949098616 scopus 로고    scopus 로고
    • Break dosage, cell cycle stage and DNA replication influence DNA double strand break response
    • Zierhut C., and Diffley J.F. Break dosage, cell cycle stage and DNA replication influence DNA double strand break response. EMBO J. 27 (2008) 1875-1885
    • (2008) EMBO J. , vol.27 , pp. 1875-1885
    • Zierhut, C.1    Diffley, J.F.2
  • 62
    • 0242721689 scopus 로고    scopus 로고
    • End resection initiates genomic instability in the absence of telomerase
    • Hackett J.A., and Greider C.W. End resection initiates genomic instability in the absence of telomerase. Mol. Cell. Biol. 23 (2003) 8450-8461
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8450-8461
    • Hackett, J.A.1    Greider, C.W.2
  • 63
    • 17044414564 scopus 로고    scopus 로고
    • Persistence of chromosome aberrations following acute radiation. I. PAINT translocations, dicentrics, rings, fragments, and insertions
    • Tucker J.D., Cofield J., Matsumoto K., Ramsey M.J., and Freeman D.C. Persistence of chromosome aberrations following acute radiation. I. PAINT translocations, dicentrics, rings, fragments, and insertions. Environ. Mol. Mutagen 45 (2005) 229-248
    • (2005) Environ. Mol. Mutagen , vol.45 , pp. 229-248
    • Tucker, J.D.1    Cofield, J.2    Matsumoto, K.3    Ramsey, M.J.4    Freeman, D.C.5
  • 64
    • 0002011265 scopus 로고    scopus 로고
    • Gene amplification in human cancers: biological and clinical significance
    • Vogelstein B., and Kinzler K.W. (Eds), McGraw-Hill, New York
    • Brodeur G.M., and Hogarety M.D. Gene amplification in human cancers: biological and clinical significance. In: Vogelstein B., and Kinzler K.W. (Eds). The Genetic Basis of Human Cancer (1998), McGraw-Hill, New York 161-172
    • (1998) The Genetic Basis of Human Cancer , pp. 161-172
    • Brodeur, G.M.1    Hogarety, M.D.2
  • 65
    • 0032823534 scopus 로고    scopus 로고
    • Oncogene amplification in solid tumors
    • Schwab M. Oncogene amplification in solid tumors. Sem. Cancer Biol. 9 (1999) 319-325
    • (1999) Sem. Cancer Biol. , vol.9 , pp. 319-325
    • Schwab, M.1
  • 66
    • 0035120289 scopus 로고    scopus 로고
    • Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease
    • Gollin S.M. Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 23 (2001) 238-253
    • (2001) Head Neck , vol.23 , pp. 238-253
    • Gollin, S.M.1
  • 68
    • 0027122767 scopus 로고
    • Chromosomal instability (Scientific Correspondence)
    • Sabatier L., Dutrillaux B., and Martin M.B. Chromosomal instability (Scientific Correspondence). Nature 357 (1992) 548
    • (1992) Nature , vol.357 , pp. 548
    • Sabatier, L.1    Dutrillaux, B.2    Martin, M.B.3
  • 69
    • 0028135452 scopus 로고
    • Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts
    • Sabatier L., Lebeau J., and Dutrillaux B. Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts. Int. J. Radiat. Biol. 66 (1994) 611-613
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 611-613
    • Sabatier, L.1    Lebeau, J.2    Dutrillaux, B.3
  • 71
    • 0037478635 scopus 로고    scopus 로고
    • Genomic instability and radiation
    • Little J.B. Genomic instability and radiation. J. Radiol. Prot. 23 (2003) 173-181
    • (2003) J. Radiol. Prot. , vol.23 , pp. 173-181
    • Little, J.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.