DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line

Neoplasia

Volumn 4, Issue 6, 2002, Pages 531-538

  Lo, Anthony W I ^a   Sabatier, Laure ^b   Fouladi, Bijan ^a   Pottiert, Géraldine ^b   Ricoul, Michelle ^b   Murnane, John P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Laboratoire de Radiobiologie et Oncologie   (France)

Author keywords

Breakage fusion bridge cycles; Chromosome fusion; Chromosome instability; DNA amplification telomere

Indexed keywords

ARTICLE; CHROMOSOME BREAKAGE; CHROMOSOME MARKER; CONTROLLED STUDY; FOLLOW UP; GENE AMPLIFICATION; GENE FUSION; GENE OVEREXPRESSION; GENETIC STABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SISTER CHROMATID EXCHANGE; TELOMERE; TUMOR CELL LINE; ANAPHASE; BLADDER TUMOR; CELL CULTURE; CHROMOSOME 16; CHROMOSOME ABERRATION; DNA DAMAGE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSFECTION; GENETICS; HERPES SIMPLEX VIRUS 1; KARYOTYPING; METABOLISM; NON-PROGRAMMATIC; PHYSIOLOGY; PLASMID; SOUTHERN BLOTTING;

DNA; THYMIDINE KINASE;

NON-PROGRAMMATIC;

ANAPHASE; BLOTTING, SOUTHERN; CHROMOSOME ABERRATIONS; CHROMOSOME BREAKAGE; CHROMOSOMES, HUMAN, PAIR 16; DNA DAMAGE; DNA, NEOPLASM; GENE AMPLIFICATION; HERPESVIRUS 1, HUMAN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; PLASMIDS; TELOMERE; THYMIDINE KINASE; TRANSFECTION; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0036858415     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.neo.7900267     Document Type: Article

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