H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes

Nature

Volumn 469, Issue 7329, 2011, Pages 245-250

  Helmink, Beth A ^a   Tubbs, Anthony T ^a   Dorsett, Yair ^a   Bednarski, Jeffrey J ^a   Walker, Laura M ^a   Feng, Zhihui ^a   Sharma, Girdhar G ^a   McKinnon, Peter J ^b   Zhang, Junran ^a   Bassing, Craig H ^c   Sleckman, Barry P ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; HISTONE H2AX; RECOMBINATION ACTIVATING GENE ENDONUCLEASE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

CELL ORGANELLE; CHROMOSOME; DNA; ENZYME ACTIVITY; GAMMA RAY RADIATION; GENE EXPRESSION; GENOMICS; HOMOLOGY; INHIBITION; MUTATION; PROTEIN; RECOMBINATION;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CELL CYCLE G1 PHASE; CHROMATIN; CHROMOSOME DELETION; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC RECOMBINATION; GENOMIC INSTABILITY; LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; G1 PHASE; GENE REARRANGEMENT, B-LYMPHOCYTE; GENOMIC INSTABILITY; HISTONES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTES; MICE; NUCLEAR PROTEINS; PRECURSOR CELLS, B-LYMPHOID; PROTEIN-SERINE-THREONINE KINASES; RECOMBINATION, GENETIC; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MURINAE;

EID: 78651406669     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09585     Document Type: Article

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