Modeling ATM mutant proteins from missense changes confirms retained kinase activity

Human Mutation

Volumn 30, Issue 8, 2009, Pages 1222-1230

  Barone, Giancarlo ^a   Groom, Alix ^a   Reiman, Anne ^a   Srinivasan, Venkataramanan ^a   Byrd, Philip J ^a   Taylor, A Malcolm R ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

ATM; ATM kinase activity; Missense mutations; Modeled mutations

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; GREEN FLUORESCENT PROTEIN; SERINE;

ARTICLE; ATAXIA TELANGIECTASIA; AUTOPHOSPHORYLATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; IONIZING RADIATION; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL DIVISION; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ENZYME ACTIVATION; G2 PHASE; HUMANS; INFRARED RAYS; MUTATION, MISSENSE; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 67749147223     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.21034     Document Type: Article

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