메뉴 건너뛰기




Volumn 36, Issue 6, 2009, Pages 954-969

CtIP Links DNA Double-Strand Break Sensing to Resection

Author keywords

DNA; PROTEINS

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; NIBRIN; PROTEIN CTLP; TRANSITION ELEMENT; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 72149103012     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.12.002     Document Type: Article
Times cited : (191)

References (45)
  • 1
    • 33646795891 scopus 로고    scopus 로고
    • Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
    • Adams K.E., Medhurst A.L., Dart D.A., and Lakin N.D. Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene 25 (2006) 3894-3904
    • (2006) Oncogene , vol.25 , pp. 3894-3904
    • Adams, K.E.1    Medhurst, A.L.2    Dart, D.A.3    Lakin, N.D.4
  • 2
    • 44349086462 scopus 로고    scopus 로고
    • Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex
    • Akamatsu Y., Murayama Y., Yamada T., Nakazaki T., Tsutsui Y., Ohta K., and Iwasaki H. Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex. Mol. Cell. Biol. 28 (2008) 3639-3651
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3639-3651
    • Akamatsu, Y.1    Murayama, Y.2    Yamada, T.3    Nakazaki, T.4    Tsutsui, Y.5    Ohta, K.6    Iwasaki, H.7
  • 3
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist C.J., and Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421 (2003) 499-506
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 4
    • 65849336044 scopus 로고    scopus 로고
    • At loose ends: resecting a double-strand break
    • Bernstein K.A., and Rothstein R. At loose ends: resecting a double-strand break. Cell 137 (2009) 807-810
    • (2009) Cell , vol.137 , pp. 807-810
    • Bernstein, K.A.1    Rothstein, R.2
  • 5
    • 59249107930 scopus 로고    scopus 로고
    • Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair
    • Budd M.E., and Campbell J.L. Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair. PLoS ONE 4 (2009) e4267
    • (2009) PLoS ONE , vol.4
    • Budd, M.E.1    Campbell, J.L.2
  • 6
    • 43149118369 scopus 로고    scopus 로고
    • Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair
    • Chen L., Nievera C.J., Lee A.Y., and Wu X. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. J. Biol. Chem. 283 (2008) 7713-7720
    • (2008) J. Biol. Chem. , vol.283 , pp. 7713-7720
    • Chen, L.1    Nievera, C.J.2    Lee, A.Y.3    Wu, X.4
  • 7
    • 47749141560 scopus 로고    scopus 로고
    • ATR: an essential regulator of genome integrity
    • Cimprich K.A., and Cortez D. ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol. 9 (2008) 616-627
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 9
    • 35848938279 scopus 로고    scopus 로고
    • The NBS1-ATM connection revisited
    • Difilippantonio S., and Nussenzweig A. The NBS1-ATM connection revisited. Cell Cycle 6 (2007) 2366-2370
    • (2007) Cell Cycle , vol.6 , pp. 2366-2370
    • Difilippantonio, S.1    Nussenzweig, A.2
  • 12
    • 15844394846 scopus 로고    scopus 로고
    • Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    • Falck J., Coates J., and Jackson S.P. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 434 (2005) 605-611
    • (2005) Nature , vol.434 , pp. 605-611
    • Falck, J.1    Coates, J.2    Jackson, S.P.3
  • 13
    • 29944434644 scopus 로고    scopus 로고
    • Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
    • Greenberg R.A., Sobhian B., Pathania S., Cantor S.B., Nakatani Y., and Livingston D.M. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 20 (2006) 34-46
    • (2006) Genes Dev. , vol.20 , pp. 34-46
    • Greenberg, R.A.1    Sobhian, B.2    Pathania, S.3    Cantor, S.B.4    Nakatani, Y.5    Livingston, D.M.6
  • 14
    • 65949113598 scopus 로고    scopus 로고
    • Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint
    • Gu B., and Chen P.L. Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint. Cell Cycle 8 (2009) 1409-1420
    • (2009) Cell Cycle , vol.8 , pp. 1409-1420
    • Gu, B.1    Chen, P.L.2
  • 15
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper J.W., and Elledge S.J. The DNA damage response: ten years after. Mol. Cell 28 (2007) 739-745
    • (2007) Mol. Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 16
    • 66149114020 scopus 로고    scopus 로고
    • Human CtIP mediates cell-cycle control of DNA-end resection and double-strand-break repair
    • Huertas P., and Jackson S.P. Human CtIP mediates cell-cycle control of DNA-end resection and double-strand-break repair. J. Biol. Chem. 284 (2009) 9558-9565
    • (2009) J. Biol. Chem. , vol.284 , pp. 9558-9565
    • Huertas, P.1    Jackson, S.P.2
  • 18
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan M.B., and Bartek J. Cell-cycle checkpoints and cancer. Nature 432 (2004) 316-323
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 19
    • 2642528031 scopus 로고    scopus 로고
    • DNA damage-induced activation of ATM and ATM-dependent signaling pathways
    • Kurz E.U., and Lees-Miller S.P. DNA damage-induced activation of ATM and ATM-dependent signaling pathways. DNA Repair (Amst.) 3 (2004) 889-900
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 889-900
    • Kurz, E.U.1    Lees-Miller, S.P.2
  • 20
    • 36949026694 scopus 로고    scopus 로고
    • Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
    • Lee J.H., and Paull T.T. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 26 (2007) 7741-7748
    • (2007) Oncogene , vol.26 , pp. 7741-7748
    • Lee, J.H.1    Paull, T.T.2
  • 21
    • 36248942617 scopus 로고    scopus 로고
    • Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
    • Lengsfeld B.M., Rattray A.J., Bhaskara V., Ghirlando R., and Paull T.T. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol. Cell 28 (2007) 638-651
    • (2007) Mol. Cell , vol.28 , pp. 638-651
    • Lengsfeld, B.M.1    Rattray, A.J.2    Bhaskara, V.3    Ghirlando, R.4    Paull, T.T.5
  • 22
    • 0034644220 scopus 로고    scopus 로고
    • Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
    • Li S., Ting N.S., Zheng L., Chen P.L., Ziv Y., Shiloh Y., Lee E.Y., and Lee W.H. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 406 (2000) 210-215
    • (2000) Nature , vol.406 , pp. 210-215
    • Li, S.1    Ting, N.S.2    Zheng, L.3    Chen, P.L.4    Ziv, Y.5    Shiloh, Y.6    Lee, E.Y.7    Lee, W.H.8
  • 23
    • 34948872046 scopus 로고    scopus 로고
    • Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
    • Limbo O., Chahwan C., Yamada Y., de Bruin R.A., Wittenberg C., and Russell P. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 28 (2007) 134-146
    • (2007) Mol. Cell , vol.28 , pp. 134-146
    • Limbo, O.1    Chahwan, C.2    Yamada, Y.3    de Bruin, R.A.4    Wittenberg, C.5    Russell, P.6
  • 24
    • 33645824088 scopus 로고    scopus 로고
    • CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression
    • Liu F., and Lee W.H. CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression. Mol. Cell. Biol. 26 (2006) 3124-3134
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 3124-3134
    • Liu, F.1    Lee, W.H.2
  • 27
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou E.P., and Symington L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455 (2008) 770-774
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 28
    • 33646777679 scopus 로고    scopus 로고
    • Rapid activation of ATR by ionizing radiation requires ATM and Mre11
    • Myers J.S., and Cortez D. Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J. Biol. Chem. 281 (2006) 9346-9350
    • (2006) J. Biol. Chem. , vol.281 , pp. 9346-9350
    • Myers, J.S.1    Cortez, D.2
  • 29
    • 37149043618 scopus 로고    scopus 로고
    • A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination
    • Penkner A., Portik-Dobos Z., Tang L., Schnabel R., Novatchkova M., Jantsch V., and Loidl J. A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J. 26 (2007) 5071-5082
    • (2007) EMBO J. , vol.26 , pp. 5071-5082
    • Penkner, A.1    Portik-Dobos, Z.2    Tang, L.3    Schnabel, R.4    Novatchkova, M.5    Jantsch, V.6    Loidl, J.7
  • 31
    • 0032502782 scopus 로고    scopus 로고
    • Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif
    • Schaeper U., Subramanian T., Lim L., Boyd J.M., and Chinnadurai G. Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J. Biol. Chem. 273 (1998) 8549-8552
    • (1998) J. Biol. Chem. , vol.273 , pp. 8549-8552
    • Schaeper, U.1    Subramanian, T.2    Lim, L.3    Boyd, J.M.4    Chinnadurai, G.5
  • 32
    • 61649093808 scopus 로고    scopus 로고
    • Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
    • Shiotani B., and Zou L. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol. Cell 33 (2009) 547-558
    • (2009) Mol. Cell , vol.33 , pp. 547-558
    • Shiotani, B.1    Zou, L.2
  • 33
    • 0026263951 scopus 로고
    • Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts
    • Smythe C., and Newport J.W. Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts. Methods Cell Biol. 35 (1991) 449-468
    • (1991) Methods Cell Biol. , vol.35 , pp. 449-468
    • Smythe, C.1    Newport, J.W.2
  • 34
    • 33749037701 scopus 로고    scopus 로고
    • Mechanism of homologous recombination: mediators and helicases take on regulatory functions
    • Sung P., and Klein H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat. Rev. Mol. Cell Biol. 7 (2006) 739-750
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 739-750
    • Sung, P.1    Klein, H.2
  • 37
    • 33747837752 scopus 로고    scopus 로고
    • CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression
    • Wu G., and Lee W.H. CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression. Cell Cycle 5 (2006) 1592-1596
    • (2006) Cell Cycle , vol.5 , pp. 1592-1596
    • Wu, G.1    Lee, W.H.2
  • 38
    • 20744436198 scopus 로고    scopus 로고
    • ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
    • You Z., Chahwan C., Bailis J., Hunter T., and Russell P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol. Cell. Biol. 25 (2005) 5363-5379
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5363-5379
    • You, Z.1    Chahwan, C.2    Bailis, J.3    Hunter, T.4    Russell, P.5
  • 40
    • 6344264992 scopus 로고    scopus 로고
    • DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
    • Yu X., and Chen J. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol. Cell. Biol. 24 (2004) 9478-9486
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9478-9486
    • Yu, X.1    Chen, J.2
  • 41
    • 33745614048 scopus 로고    scopus 로고
    • BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP
    • Yu X., Fu S., Lai M., Baer R., and Chen J. BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP. Genes Dev. 20 (2006) 1721-1726
    • (2006) Genes Dev. , vol.20 , pp. 1721-1726
    • Yu, X.1    Fu, S.2    Lai, M.3    Baer, R.4    Chen, J.5
  • 42
    • 70450242630 scopus 로고    scopus 로고
    • N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair
    • Yuan J., and Chen J. N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair. J. Biol. Chem. 284 (2009) 31746-31752
    • (2009) J. Biol. Chem. , vol.284 , pp. 31746-31752
    • Yuan, J.1    Chen, J.2
  • 43
    • 67349246802 scopus 로고    scopus 로고
    • CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
    • Yun M.H., and Hiom K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 459 (2009) 460-463
    • (2009) Nature , vol.459 , pp. 460-463
    • Yun, M.H.1    Hiom, K.2
  • 44
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • Zhu Z., Chung W.H., Shim E.Y., Lee S.E., and Ira G. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134 (2008) 981-994
    • (2008) Cell , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5
  • 45
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L., and Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300 (2003) 1542-1548
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.