Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex

Journal of Biological Chemistry

Volumn 287, Issue 7, 2012, Pages 4936-4945

  Sun, Jingxin ^a   Lee, Kyung Jong ^a   Davis, Anthony J ^a   Chen, David J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPETITION MODEL; DNA DOUBLE STRAND BREAKS; DOUBLE STRANDS; ENDONUCLEASE ACTIVITIES; EXONUCLEASE; GENETIC DATA; HOMOLOGOUS RECOMBINATION; IN-VITRO; NONHOMOLOGOUS END JOINING; PROTEIN COMPLEXES;

PROTEINS; YEAST;

DNA;

CELL PROTEIN; DEOXYRIBONUCLEASE; DOUBLE STRANDED DNA; EXONUCLEASE; EXONUCLEASE 1; KU ANTIGEN; KU80 PROTEIN; MRE11 PROTEIN; RAD50 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; METABOLIC INHIBITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

ANTIGENS, NUCLEAR; DNA; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EXODEOXYRIBONUCLEASES; HUMANS; MULTIPROTEIN COMPLEXES;

EID: 84863152463     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.306167     Document Type: Article

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