Limiting the persistence of a chromosome break diminishes its mutagenic potential

PLoS Genetics

Volumn 5, Issue 10, 2009, Pages

  Bennardo, Nicole ^a   Gunn, Amanda ^a   Cheng, Anita ^a   Hasty, Paul ^b   Stark, Jeremy M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; EXONUCLEASE; I SCEL PROTEIN; TREX2 PROTEIN; UNCLASSIFIED DRUG; EXODEOXYRIBONUCLEASE; SACCHAROMYCES CEREVISIAE PROTEIN; SCEI PROTEIN, S CEREVISIAE; TREX2 PROTEIN, MOUSE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

3' UNTRANSLATED REGION; ARTICLE; CHROMOSOME BREAKAGE; DOUBLE STRANDED DNA BREAK; HEREDITY; HOMOLOGOUS RECOMBINATION; INDEL MUTATION; MUTAGENESIS; PREDICTOR VARIABLE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; TANDEM REPEAT; ANIMAL; CELL CULTURE; DNA REPAIR; GENETICS; METABOLISM; MOUSE;

ANIMALS; CELLS, CULTURED; CHROMOSOME BREAKAGE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; EXODEOXYRIBONUCLEASES; MICE; MUTAGENESIS; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 73349098442     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000683     Document Type: Article

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