-
1
-
-
84862865669
-
Immunoglobulin class switching: Induction, targeting and beyond
-
Xu, Z., H. Zan, E. J. Pone, T. Mai, and P. Casali. 2012. Immunoglobulin class switching: induction, targeting and beyond. Nature Rev. Immunol. 12: 517-531
-
(2012)
Nature Rev. Immunol.
, vol.12
, pp. 517-531
-
-
Xu, Z.1
Zan, H.2
Pone, E.J.3
Mai, T.4
Casali, P.5
-
2
-
-
84870427871
-
Rev1 recruits Ung to switch regions and enhances du deglycosylation for immunoglobulin class switch DNA recombination
-
Zan, H., C. A. White, L. M. Thomas, et al. 2012. Rev1 recruits Ung to switch regions and enhances dU deglycosylation for immunoglobulin class switch DNA recombination. Cell Repts. 2: 1220-1232
-
(2012)
Cell Repts.
, vol.2
, pp. 1220-1232
-
-
Zan, H.1
White, C.A.2
Thomas, L.M.3
-
3
-
-
77955660238
-
Helicobacter pyloriinduced activation-induced cytidine deaminase expression and carcinogenesis
-
Marusawa, H., and T. Chiba. 2010. Helicobacter pyloriinduced activation-induced cytidine deaminase expression and carcinogenesis. Curr. Opin. Immunol. 22: 442-447
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 442-447
-
-
Marusawa, H.1
Chiba, T.2
-
4
-
-
80053451874
-
Role of activation-induced cytidine deaminase in inflammationassociated cancer development
-
Marusawa, H., A. Takai, and T. Chiba. 2011. Role of activation-induced cytidine deaminase in inflammationassociated cancer development. Adv. Immunol. 111: 109-141
-
(2011)
Adv. Immunol.
, vol.111
, pp. 109-141
-
-
Marusawa, H.1
Takai, A.2
Chiba, T.3
-
5
-
-
38049012778
-
Regulation of aicda expression and AID activity: Relevance to somatic hypermutation and class switch DNA recombination
-
Xu, Z., E. J. Pone, A. Al-Qahtani, et al. 2007. Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Crit. Rev. Immunol. 27: 367-397
-
(2007)
Crit. Rev. Immunol.
, vol.27
, pp. 367-397
-
-
Xu, Z.1
Pone, E.J.2
Al-Qahtani, A.3
-
6
-
-
79955632686
-
Complex regulation and function of activation-induced cytidine deaminase
-
Stavnezer, J. 2011. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol. 32: 194-201
-
(2011)
Trends Immunol.
, vol.32
, pp. 194-201
-
-
Stavnezer, J.1
-
7
-
-
79961011020
-
Activationinduced cytidine deaminase mediates central tolerance in B cells
-
Kuraoka, M., T. M. Holl, D. Liao, et al. 2011. Activationinduced cytidine deaminase mediates central tolerance in B cells. Proc. Natl. Acad. Sci. USA 108: 11560-11565
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11560-11565
-
-
Kuraoka, M.1
Holl, T.M.2
Liao, D.3
-
8
-
-
79960998395
-
Activationinduced cytidine deaminase (AID) is required for B-cell tolerance in humans
-
Meyers, G., Y. S. Ng, J. M. Bannock, et al. 2011. Activationinduced cytidine deaminase (AID) is required for B-cell tolerance in humans. Proc. Natl. Acad. Sci. USA 108: 11554-11559
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11554-11559
-
-
Meyers, G.1
Ng, Y.S.2
Bannock, J.M.3
-
9
-
-
37549068541
-
AID is required for germinal center-derived lymphomagenesis
-
Pasqualucci, L., G. Bhagat, M. Jankovic, et al. 2008. AID is required for germinal center-derived lymphomagenesis. Nat. Genet. 40: 108-112
-
(2008)
Nat. Genet.
, vol.40
, pp. 108-112
-
-
Pasqualucci, L.1
Bhagat, G.2
Jankovic, M.3
-
10
-
-
70449641054
-
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
-
Robbiani, D. F., S. Bunting, N. Feldhahn, et al. 2009. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol. Cell 36: 631-641
-
(2009)
Mol. Cell
, vol.36
, pp. 631-641
-
-
Robbiani, D.F.1
Bunting, S.2
Feldhahn, N.3
-
11
-
-
77955921194
-
Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination
-
Hasham, M. G., N. M. Donghia, E. Coffey, et al. 2010. Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination. Nat. Immunol. 11: 820-826
-
(2010)
Nat. Immunol.
, vol.11
, pp. 820-826
-
-
Hasham, M.G.1
Donghia, N.M.2
Coffey, E.3
-
12
-
-
4644257592
-
AID is required for c-Myc/IgH chromosome translocations in vivo
-
Ramiro, A. R., M. Jankovic, T. Eisenreich, et al. 2004. AID is required for c-Myc/IgH chromosome translocations in vivo. Cell 118: 431-438
-
(2004)
Cell
, vol.118
, pp. 431-438
-
-
Ramiro, A.R.1
Jankovic, M.2
Eisenreich, T.3
-
13
-
-
57149146036
-
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
-
Robbiani, D. F., A. Bothmer, E. Callen, et al. 2008. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 135: 1028-1038
-
(2008)
Cell
, vol.135
, pp. 1028-1038
-
-
Robbiani, D.F.1
Bothmer, A.2
Callen, E.3
-
14
-
-
70350464349
-
A coming-of-age story: Activation-induced cytidine deaminase turns 10
-
Delker, R. K., S. D. Fugmann, and F. N. Papavasiliou. 2009. A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat. Immunol. 10: 1147-1153
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1147-1153
-
-
Delker, R.K.1
Fugmann, S.D.2
Papavasiliou, F.N.3
-
15
-
-
81055141344
-
Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1a (eEF1A)
-
Hasler, J., C. Rada, and M. S. Neuberger. 2011. Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1a (eEF1A). Proc. Natl. Acad. Sci. USA 108: 18366-18371
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 18366-18371
-
-
Hasler, J.1
Rada, C.2
Neuberger, M.S.3
-
16
-
-
45149088174
-
Proteasomal degradation restricts the nuclear lifespan of AID
-
Aoufouchi, S., A. Faili, C. Zober, et al. 2008. Proteasomal degradation restricts the nuclear lifespan of AID. J. Exp.Med. 205: 1357-1368
-
(2008)
J. Exp.Med.
, vol.205
, pp. 1357-1368
-
-
Aoufouchi, S.1
Faili, A.2
Zober, C.3
-
17
-
-
84855509602
-
REG-g associates with and modulates the abundance of nuclear activation-induced deaminase
-
Uchimura, Y., L. F. Barton, C. Rada, and M. S. Neuberger. 2011. REG-g associates with and modulates the abundance of nuclear activation-induced deaminase. J. Exp. Med. 208: 2385-2891
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2385-2891
-
-
Uchimura, Y.1
Barton, L.F.2
Rada, C.3
Neuberger, M.S.4
-
18
-
-
84862297357
-
Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination
-
Li, G., E. J. Pone, T. Mai, et al. 2012. Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination. J. Biol. Chem. 287: 21520-21529
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 21520-21529
-
-
Li, G.1
Pone, E.J.2
Mai, T.3
-
19
-
-
3242795967
-
Separate domains of AID are required for somatic hypermutation and class-switch recombination
-
Shinkura, R., S. Ito, N. A. Begum, et al. 2004. Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat. Immunol. 5: 707-712
-
(2004)
Nat. Immunol.
, vol.5
, pp. 707-712
-
-
Shinkura, R.1
Ito, S.2
Begum, N.A.3
-
20
-
-
84860292969
-
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-kB pathway
-
Pone, E. J., J. Zhang, T. Mai, et al. 2012. BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-kB pathway. Nat. Commun. 3: 767
-
(2012)
Nat. Commun.
, vol.3
, pp. 767
-
-
Pone, E.J.1
Zhang, J.2
Mai, T.3
-
21
-
-
0038658816
-
The CD40-CD154 interaction in B cell-T cell liaisons
-
Bishop, G. A., and B. S. Hostager. 2003. The CD40-CD154 interaction in B cell-T cell liaisons. Cytokine Growth Factor Rev. 14: 297-309
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 297-309
-
-
Bishop, G.A.1
Hostager, B.S.2
-
22
-
-
77955903717
-
Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1
-
Graham, J. P., K. M. Arcipowski, and G. A. Bishop. 2010. Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1. Immunol. Rev. 237: 226-248
-
(2010)
Immunol. Rev.
, vol.237
, pp. 226-248
-
-
Graham, J.P.1
Arcipowski, K.M.2
Bishop, G.A.3
-
23
-
-
80054875478
-
Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease
-
Rickert, R. C., J. Jellusova, and A. V. Miletic. 2011. Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease. Immunol. Rev. 244: 115-133
-
(2011)
Immunol. Rev.
, vol.244
, pp. 115-133
-
-
Rickert, R.C.1
Jellusova, J.2
Miletic, A.V.3
-
25
-
-
78650920066
-
Non-canonical NF-kB signaling pathway
-
Sun, S. C. 2011. Non-canonical NF-kB signaling pathway. Cell Res. 21: 71-85
-
(2011)
Cell Res.
, vol.21
, pp. 71-85
-
-
Sun, S.C.1
-
26
-
-
75649096381
-
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
-
Tran, T. H., M. Nakata, K. Suzuki, et al. 2010. B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers. Nat. Immunol. 11: 148-154
-
(2010)
Nat. Immunol.
, vol.11
, pp. 148-154
-
-
Tran, T.H.1
Nakata, M.2
Suzuki, K.3
-
27
-
-
44349195660
-
The regulation of IgA class switching
-
Cerutti, A. 2008. The regulation of IgA class switching. Nat. Rev. Immunol. 8: 421-434
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 421-434
-
-
Cerutti, A.1
-
28
-
-
77952311371
-
Adaptive immune regulation in the gut: T celldependent and T cell-independent IgA synthesis
-
Fagarasan, S., S. Kawamoto, O. Kanagawa, and K. Suzuki. 2010. Adaptive immune regulation in the gut: T celldependent and T cell-independent IgA synthesis. Annu. Rev. Immunol. 28: 243-273
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 243-273
-
-
Fagarasan, S.1
Kawamoto, S.2
Kanagawa, O.3
Suzuki, K.4
-
29
-
-
79953036467
-
Immunoglobulin responses at the mucosal interfaces
-
Cerutti, A., K. Chen, and A. Chorny. 2011. Immunoglobulin responses at the mucosal interfaces. Annu. Rev. Immunol. 29: 273-293
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 273-293
-
-
Cerutti, A.1
Chen, K.2
Chorny, A.3
-
30
-
-
33747837100
-
BAFF, APRIL and their receptors: Structure, function and signaling
-
Bossen, C., and P. Schneider. 2006. BAFF, APRIL and their receptors: structure, function and signaling. Semin. Immunol. 18: 263-275
-
(2006)
Semin. Immunol.
, vol.18
, pp. 263-275
-
-
Bossen, C.1
Schneider, P.2
-
32
-
-
4644241216
-
CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10
-
He, B., X. Qiao, and A. Cerutti. 2004. CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. J. Immunol. 173: 4479-4491
-
(2004)
J. Immunol.
, vol.173
, pp. 4479-4491
-
-
He, B.1
Qiao, X.2
Cerutti, A.3
-
33
-
-
47949102460
-
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF
-
Xu, W., P. A. Santini, A. J. Matthews, et al. 2008. Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. J. Immunol. 181: 276-287
-
(2008)
J. Immunol.
, vol.181
, pp. 276-287
-
-
Xu, W.1
Santini, P.A.2
Matthews, A.J.3
-
34
-
-
77955921430
-
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88
-
He, B., R. Santamaria, W. Xu, et al. 2010. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat. Immunol. 11: 836-845
-
(2010)
Nat. Immunol.
, vol.11
, pp. 836-845
-
-
He, B.1
Santamaria, R.2
Xu, W.3
-
35
-
-
80052502019
-
A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells
-
Bombardieri, M., N. W. Kam, F. Brentano, et al. 2011. A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Ann. Rheum. Dis. 70: 1857-1865
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1857-1865
-
-
Bombardieri, M.1
Kam, N.W.2
Brentano, F.3
-
36
-
-
0033822039
-
B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms
-
Vos, Q., A. Lees, Z. Q. Wu, C. M. Snapper, and J. J. Mond. 2000. B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms. Immunol. Rev. 176: 154-170
-
(2000)
Immunol. Rev.
, vol.176
, pp. 154-170
-
-
Vos, Q.1
Lees, A.2
Wu, Z.Q.3
Snapper, C.M.4
Mond, J.J.5
-
37
-
-
0242467623
-
Innate immunity: From lymphocyte mitogens to Toll-like receptors and back
-
Coutinho, A., and A. Poltorack. 2003. Innate immunity: from lymphocyte mitogens to Toll-like receptors and back. Curr. Opin. Immunol. 15: 599-602
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 599-602
-
-
Coutinho, A.1
Poltorack, A.2
-
38
-
-
77950967415
-
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: Relevance to microbial antibody responses
-
Pone, E. J., H. Zan, J. Zhang, et al. 2010. Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Crit. Rev. Immunol. 30: 1-29
-
(2010)
Crit. Rev. Immunol.
, vol.30
, pp. 1-29
-
-
Pone, E.J.1
Zan, H.2
Zhang, J.3
-
39
-
-
84860311836
-
B cell TLRs and induction of immunoglobulin class-switch DNA recombination
-
Pone, E. J., Z. Xu, C. A. White, H. Zan, and P. Casali. 2012. B cell TLRs and induction of immunoglobulin class-switch DNA recombination. Front. Biosci. 17: 2594-2615
-
(2012)
Front. Biosci.
, vol.17
, pp. 2594-2615
-
-
Pone, E.J.1
Xu, Z.2
White, C.A.3
Zan, H.4
Casali, P.5
-
40
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov, R. 2007. Recognition of microorganisms and activation of the immune response. Nature 449: 819-826
-
(2007)
Nature
, vol.449
, pp. 819-826
-
-
Medzhitov, R.1
-
41
-
-
34548656855
-
Signaling pathways downstream of pattern-recognition receptors and their cross talk
-
Lee, M. S., and Y. J. Kim. 2007. Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu. Rev. Biochem. 76: 447-480
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 447-480
-
-
Lee, M.S.1
Kim, Y.J.2
-
42
-
-
63649108380
-
The roles of TLRs, RLRs and NLRs in pathogen recognition
-
Kawai, T., and S. Akira. 2009. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 21: 317-337
-
(2009)
Int. Immunol.
, vol.21
, pp. 317-337
-
-
Kawai, T.1
Akira, S.2
-
43
-
-
41149150143
-
Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets
-
Gururajan, M., J. Jacob, and B. Pulendran. 2007. Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets. PLoS One 2: e863
-
(2007)
PLoS One
, vol.2
-
-
Gururajan, M.1
Jacob, J.2
Pulendran, B.3
-
44
-
-
0016410603
-
Thymus-independent Bcell induction and paralysis
-
Coutinho, A., and G. Moller. 1975. Thymus-independent Bcell induction and paralysis. Adv. Immunol. 21: 113-236
-
(1975)
Adv. Immunol.
, vol.21
, pp. 113-236
-
-
Coutinho, A.1
Moller, G.2
-
45
-
-
0023522520
-
Tindependent activation of single B cells: An orderly analysis of overlapping stages in the activation pathway
-
Pike, B. L., M. R. Alderson, and G. J. Nossal. 1987. Tindependent activation of single B cells: an orderly analysis of overlapping stages in the activation pathway. Immunol. Rev. 99: 119-152
-
(1987)
Immunol. Rev.
, vol.99
, pp. 119-152
-
-
Pike, B.L.1
Alderson, M.R.2
Nossal, G.J.3
-
46
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., P. Preston-Hurlburt, and C. A. Janeway, Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
47
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., X. He, I. Smirnova, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282: 2085-2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
48
-
-
0028806967
-
Antibodies to lipopolysaccharide
-
Poxton, I. R. 1995. Antibodies to lipopolysaccharide. J. Immunol. Meth. 186: 1-15
-
(1995)
J. Immunol. Meth.
, vol.186
, pp. 1-15
-
-
Poxton, I.R.1
-
49
-
-
55849100752
-
Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation
-
Quintana, F. J., A. Solomon, I. R. Cohen, and G. Nussbaum. 2008. Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation. PLoS One 3: e3509
-
(2008)
PLoS One
, vol.3
-
-
Quintana, F.J.1
Solomon, A.2
Cohen, I.R.3
Nussbaum, G.4
-
50
-
-
44649161194
-
The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens
-
Chaturvedi, A., D. Dorward, and S. K. Pierce. 2008. The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity 28: 799-809
-
(2008)
Immunity
, vol.28
, pp. 799-809
-
-
Chaturvedi, A.1
Dorward, D.2
Pierce, S.K.3
-
51
-
-
65749104837
-
How location governs Toll-like receptor signaling
-
Chaturvedi, A., and S. K. Pierce. 2009. How location governs Toll-like receptor signaling. Traffic 10: 621-628
-
(2009)
Traffic
, vol.10
, pp. 621-628
-
-
Chaturvedi, A.1
Pierce, S.K.2
-
52
-
-
84862123066
-
The role of activation-induced cytidine deaminase in lymphomagenesis
-
Gu, X., V. Shivarov, and M. P. Strout. 2012. The role of activation-induced cytidine deaminase in lymphomagenesis. Curr. Opin. Hematol. 19: 292-298
-
(2012)
Curr. Opin. Hematol.
, vol.19
, pp. 292-298
-
-
Gu, X.1
Shivarov, V.2
Strout, M.P.3
-
53
-
-
57749181557
-
Haploinsufficiency of activationinduced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo
-
Sernández, I. V., V. G. de Yébenes, Y. Dorsett, and A. R. Ramiro. 2008. Haploinsufficiency of activationinduced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo. PLoS One 3: e3927
-
(2008)
PLoS One
, vol.3
-
-
Sernández, I.V.1
De Yébenes, V.G.2
Dorsett, Y.3
Ramiro, A.R.4
-
54
-
-
51049110262
-
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development
-
Takizawa, M., H. Tolarova, Z. Li, et al. 2008. AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development. J. Exp. Med. 205: 1949-1957
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1949-1957
-
-
Takizawa, M.1
Tolarova, H.2
Li, Z.3
-
55
-
-
59049098881
-
Lupus-prone MRL/Fas lpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: Concurrent up-regulation of somatic hypermutation and class switch DNA recombination
-
Zan, H., J. Zhang, S. Ardeshna, et al. 2009. Lupus-prone MRL/Fas lpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent up-regulation of somatic hypermutation and class switch DNA recombination. Autoimmunity 42: 89-103
-
(2009)
Autoimmunity
, vol.42
, pp. 89-103
-
-
Zan, H.1
Zhang, J.2
Ardeshna, S.3
-
56
-
-
24944541376
-
Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination
-
Rush, J. S., M. Liu, V. H. Odegard, S. Unniraman, and D. G. Schatz. 2005. Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination. Proc. Natl. Acad. Sci. USA 102: 13242-13247
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13242-13247
-
-
Rush, J.S.1
Liu, M.2
Odegard, V.H.3
Unniraman, S.4
Schatz, D.G.5
-
57
-
-
84858796247
-
Integration of B cell responses through Toll-like receptors and antigen receptors
-
Rawlings, D. J., M. A. Schwartz, S. W. Jackson, and A. Meyer-Bahlburg. 2012. Integration of B cell responses through Toll-like receptors and antigen receptors. Nat. Rev. Immunol. 12: 282-294
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 282-294
-
-
Rawlings, D.J.1
Schwartz, M.A.2
Jackson, S.W.3
Meyer-Bahlburg, A.4
-
58
-
-
2542527768
-
Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kB activation pathways
-
Zarnegar, B., J. Q. He, G. Oganesyan, et al. 2004. Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kB activation pathways. Proc. Natl. Acad. Sci. USA 101: 8108-8113
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8108-8113
-
-
Zarnegar, B.1
He, J.Q.2
Oganesyan, G.3
-
59
-
-
67349090990
-
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation
-
Park, S. R., H. Zan, Z. Pal, et al. 2009. HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nat. Immunol. 10: 540-550
-
(2009)
Nat. Immunol.
, vol.10
, pp. 540-550
-
-
Park, S.R.1
Zan, H.2
Pal, Z.3
-
60
-
-
80051988785
-
Hierarchies of NF-kB target-gene regulation
-
Smale, S. T. 2011. Hierarchies of NF-kB target-gene regulation. Nat. Immunol. 12: 689-694
-
(2011)
Nat. Immunol.
, vol.12
, pp. 689-694
-
-
Smale, S.T.1
-
61
-
-
80051959463
-
NF-kB is 25
-
Baltimore, D. 2011. NF-kB is 25. Nat. Immunol. 12: 683-685
-
(2011)
Nat. Immunol.
, vol.12
, pp. 683-685
-
-
Baltimore, D.1
-
62
-
-
0038515309
-
E-proteins directly regulate expression of activation-induced deaminase in mature B cells
-
Sayegh, C. E., M. W. Quong, Y. Agata, and C. Murre. 2003. E-proteins directly regulate expression of activation-induced deaminase in mature B cells. Nat. Immunol. 4: 586-593
-
(2003)
Nat. Immunol.
, vol.4
, pp. 586-593
-
-
Sayegh, C.E.1
Quong, M.W.2
Agata, Y.3
Murre, C.4
-
63
-
-
79956081339
-
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
-
Ise, W., M. Kohyama, B. U. Schraml, et al. 2011. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat. Immunol. 12: 536-543
-
(2011)
Nat. Immunol.
, vol.12
, pp. 536-543
-
-
Ise, W.1
Kohyama, M.2
Schraml, B.U.3
-
64
-
-
84859892863
-
MicroRNA profiling: Approaches and considerations
-
Pritchard, C. C., H. H. Cheng, and M. Tewari. 2012. MicroRNA profiling: approaches and considerations. Nat. Rev. Genet. 13: 358-369
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 358-369
-
-
Pritchard, C.C.1
Cheng, H.H.2
Tewari, M.3
-
65
-
-
43049178852
-
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase
-
Teng, G., P. Hakimpour, P. Landgraf, et al. 2008. MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. Immunity 28: 621-629
-
(2008)
Immunity
, vol.28
, pp. 621-629
-
-
Teng, G.1
Hakimpour, P.2
Landgraf, P.3
-
66
-
-
43049173617
-
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-IgH translocation
-
Dorsett, Y., K. M. McBride, M. Jankovic, et al. 2008. MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-IgH translocation. Immunity 28: 630-638
-
(2008)
Immunity
, vol.28
, pp. 630-638
-
-
Dorsett, Y.1
McBride, K.M.2
Jankovic, M.3
-
67
-
-
53349129731
-
MiR-181b negatively regulates activation-induced cytidine deaminase in B cells
-
de Yébenes, V. G., L. Belver, D. G. Pisano, et al. 2008. miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J. Exp. Med. 205: 2199-2206
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2199-2206
-
-
De Yébenes, V.G.1
Belver, L.2
Pisano, D.G.3
-
68
-
-
81155158874
-
Repression of human activation induced cytidine deaminase by miR-93 and miR-155
-
Borchert, G. M., N. W. Holton, and E. D. Larson. 2011. Repression of human activation induced cytidine deaminase by miR-93 and miR-155. BMC Cancer 10: 347
-
(2011)
BMC Cancer
, vol.10
, pp. 347
-
-
Borchert, G.M.1
Holton, N.W.2
Larson, E.D.3
-
69
-
-
84872255978
-
Bc16 positively regulates AID and germinal center gene expression via repression of miR-155
-
Basso, K., C. Schneider, Q. Shen, et al. 2012. Bc16 positively regulates AID and germinal center gene expression via repression of miR-155. J. Exp. Med. 209: 2455-2465
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2455-2465
-
-
Basso, K.1
Schneider, C.2
Shen, Q.3
-
70
-
-
34247594818
-
Regulation of the germinal center response by microRNA-155
-
Thai, T. H., D. P. Calado, S. Casola, et al. 2007. Regulation of the germinal center response by microRNA-155. Science 316: 604-608
-
(2007)
Science
, vol.316
, pp. 604-608
-
-
Thai, T.H.1
Calado, D.P.2
Casola, S.3
-
71
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf, P., M. Rusu, R. Sheridan, et al. 2007. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
-
72
-
-
34249945558
-
Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma
-
Kluiver, J., A. van den Berg, D. de Jong, et al. 2007. Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma. Oncogene 26: 3769-3776
-
(2007)
Oncogene
, vol.26
, pp. 3769-3776
-
-
Kluiver, J.1
Berg Den A.Van2
De Jong, D.3
-
73
-
-
1242341972
-
Activationinduced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
-
Ito, S., H. Nagaoka, R. Shinkura, et al. 2004. Activationinduced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1. Proc. Natl. Acad. Sci. USA 101: 1975-1980
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1975-1980
-
-
Ito, S.1
Nagaoka, H.2
Shinkura, R.3
-
74
-
-
33646596305
-
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells
-
Cattoretti, G., M. Buttner, R. Shaknovich, et al. 2006. Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells. Blood 107: 3967-3975
-
(2006)
Blood
, vol.107
, pp. 3967-3975
-
-
Cattoretti, G.1
Buttner, M.2
Shaknovich, R.3
-
75
-
-
8644241815
-
Expression of the AID protein in normal and neoplastic B cells
-
Pasqualucci, L., R. Guglielmino, J. Houldsworth, et al. 2004. Expression of the AID protein in normal and neoplastic B cells. Blood 104: 3318-3325
-
(2004)
Blood
, vol.104
, pp. 3318-3325
-
-
Pasqualucci, L.1
Guglielmino, R.2
Houldsworth, J.3
-
76
-
-
2442474264
-
Somatic hypermutation is limited by CRM1-dependent nuclear export of activationinduced deaminase
-
McBride, K. M., V. Barreto, A. R. Ramiro, P. Stavropoulos, and M. C. Nussenzweig. 2004. Somatic hypermutation is limited by CRM1-dependent nuclear export of activationinduced deaminase. J. Exp. Med. 199: 1235-1244
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1235-1244
-
-
McBride, K.M.1
Barreto, V.2
Ramiro, A.R.3
Stavropoulos, P.4
Nussenzweig, M.C.5
-
77
-
-
2942722486
-
Activationinduced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks
-
Brar, S. S., M. Watson, and M. Diaz. 2004. Activationinduced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks. J. Biol. Chem. 279: 26395-26401
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26395-26401
-
-
Brar, S.S.1
Watson, M.2
Diaz, M.3
-
78
-
-
84861326698
-
YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels
-
Zaprazna, K., and M. L. Atchison. 2012. YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels. Mol. Cell. Biol. 32: 1542-1554
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 1542-1554
-
-
Zaprazna, K.1
Atchison, M.L.2
-
80
-
-
78649404299
-
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90
-
Orthwein, A., A. M. Patenaude, el B. Affar, et al. 2010. Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90. J. Exp. Med. 207: 2751-2765
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2751-2765
-
-
Orthwein, A.1
Patenaude, A.M.2
Affar, E.B.3
-
81
-
-
84856472936
-
Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1
-
Orthwein, A., A. Zahn, S. P. Methot, et al. 2011. Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1. EMBO J. 31: 679-691
-
(2011)
EMBO J.
, vol.31
, pp. 679-691
-
-
Orthwein, A.1
Zahn, A.2
Methot, S.P.3
-
82
-
-
4344700569
-
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets
-
Chaudhuri, J., C. Khuong, and F. W. Alt. 2004. Replication protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature 430: 992-998
-
(2004)
Nature
, vol.430
, pp. 992-998
-
-
Chaudhuri, J.1
Khuong, C.2
Alt, F.W.3
-
83
-
-
28544438261
-
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation
-
Basu, U., J. Chaudhuri, C. Alpert, et al. 2005. The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation. Nature 438: 508-511
-
(2005)
Nature
, vol.438
, pp. 508-511
-
-
Basu, U.1
Chaudhuri, J.2
Alpert, C.3
-
84
-
-
33745048221
-
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation
-
McBride, K. M., A. Gazumyan, E. M. Woo, et al. 2006. Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc. Natl. Acad. Sci. USA 103: 8798-8803
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8798-8803
-
-
McBride, K.M.1
Gazumyan, A.2
Woo, E.M.3
-
85
-
-
31044435055
-
PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells
-
Pasqualucci, L., Y. Kitaura, H. Gu, and R. Dalla-Favera. 2006. PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells. Proc. Natl. Acad. Sci. USA 103: 395-400
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 395-400
-
-
Pasqualucci, L.1
Kitaura, Y.2
Gu, H.3
Dalla-Favera, R.4
-
86
-
-
0038293484
-
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
-
Ramiro, A. R., P. Stavropoulos, M. Jankovic, and M. C. Nussenzweig. 2003. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat. Immunol. 4: 452-456
-
(2003)
Nat. Immunol.
, vol.4
, pp. 452-456
-
-
Ramiro, A.R.1
Stavropoulos, P.2
Jankovic, M.3
Nussenzweig, M.C.4
-
87
-
-
0038664358
-
The influence of transcriptional orientation on endogenous switch region function
-
Shinkura, R., M. Tian, M. Smith, et al. 2003. The influence of transcriptional orientation on endogenous switch region function. Nat. Immunol. 4: 435-441
-
(2003)
Nat. Immunol.
, vol.4
, pp. 435-441
-
-
Shinkura, R.1
Tian, M.2
Smith, M.3
-
88
-
-
0037650190
-
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
-
Yu, K., F. Chedin, C. L. Hsieh, T. E. Wilson, and M. R. Lieber. 2003. R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat. Immunol. 4: 442-451
-
(2003)
Nat. Immunol.
, vol.4
, pp. 442-451
-
-
Yu, K.1
Chedin, F.2
Hsieh, C.L.3
Wilson, T.E.4
Lieber, M.R.5
-
89
-
-
0346362489
-
Transcriptioncoupled events associating with immunoglobulin switch region chromatin
-
Nambu, Y., M. Sugai, H. Gonda, et al. 2003. Transcriptioncoupled events associating with immunoglobulin switch region chromatin. Science 302: 2137-2140
-
(2003)
Science
, vol.302
, pp. 2137-2140
-
-
Nambu, Y.1
Sugai, M.2
Gonda, H.3
-
90
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
Liu, M., J. L. Duke, D. J. Richter, et al. 2008. Two levels of protection for the B cell genome during somatic hypermutation. Nature 451: 841-845
-
(2008)
Nature
, vol.451
, pp. 841-845
-
-
Liu, M.1
Duke, J.L.2
Richter, D.J.3
-
91
-
-
78651468710
-
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells
-
Staszewski, O., R. E. Baker, A. J. Ucher, et al. 2011. Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells. Mol. Cell 41: 232-242
-
(2011)
Mol. Cell
, vol.41
, pp. 232-242
-
-
Staszewski, O.1
Baker, R.E.2
Ucher, A.J.3
-
92
-
-
80053502216
-
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes
-
Klein, I. A., W. Resch, M. Jankovic, et al. 2011. Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes. Cell 147: 95-106
-
(2011)
Cell
, vol.147
, pp. 95-106
-
-
Klein, I.A.1
Resch, W.2
Jankovic, M.3
-
93
-
-
80053558376
-
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
-
Chiarle, R., Y. Zhang, R. L. Frock, et al. 2011. Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell 147: 107-119
-
(2011)
Cell
, vol.147
, pp. 107-119
-
-
Chiarle, R.1
Zhang, Y.2
Frock, R.L.3
-
94
-
-
77956345401
-
14-3-3 adaptor proteins recruit AID to 50-AGCT-30-rich switch regions for class switch recombination
-
Xu, Z., Z. Fulop, G.Wu, et al. 2010. 14-3-3 adaptor proteins recruit AID to 50-AGCT-30-rich switch regions for class switch recombination. Nature Struct. Mol. Biol. 17: 1124-1135
-
(2010)
Nature Struct. Mol. Biol.
, vol.17
, pp. 1124-1135
-
-
Xu, Z.1
Fulop, Z.2
Wu, G.3
-
95
-
-
66049129496
-
The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription
-
Shen, H. M., M. G. Poirier, M. J. Allen, et al. 2009. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. J. Exp. Med. 206: 1057-1071
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1057-1071
-
-
Shen, H.M.1
Poirier, M.G.2
Allen, M.J.3
-
96
-
-
49349112190
-
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1
-
Conticello, S. G., K. Ganesh, K. Xue, et al. 2008. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol. Cell 31: 474-484
-
(2008)
Mol. Cell
, vol.31
, pp. 474-484
-
-
Conticello, S.G.1
Ganesh, K.2
Xue, K.3
-
97
-
-
77957239251
-
Activationinduced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
-
Pavri, R., A. Gazumyan, M. Jankovic, et al. 2010. Activationinduced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell 143: 122-133
-
(2010)
Cell
, vol.143
, pp. 122-133
-
-
Pavri, R.1
Gazumyan, A.2
Jankovic, M.3
-
98
-
-
77954901696
-
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA
-
Maeda, K., S. K. Singh, K. Eda, et al. 2010. GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. J. Biol. Chem. 285: 23945-23953
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 23945-23953
-
-
Maeda, K.1
Singh, S.K.2
Eda, K.3
-
99
-
-
79956357750
-
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
-
Okazaki, I. M., K. Okawa, M. Kobayashi, et al. 2011. Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation. Proc. Natl. Acad. Sci. USA 108: 7920-7925
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7920-7925
-
-
Okazaki, I.M.1
Okawa, K.2
Kobayashi, M.3
-
100
-
-
78751608734
-
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA
-
Nowak, U., A. J. Matthews, S. Zheng, and J. Chaudhuri. 2011. The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA. Nat. Immunol. 12: 160-166
-
(2011)
Nat. Immunol.
, vol.12
, pp. 160-166
-
-
Nowak, U.1
Matthews, A.J.2
Zheng, S.3
Chaudhuri, J.4
-
101
-
-
79551681406
-
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
-
Basu, U., F. L. Meng, C. Keim, et al. 2011. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 144: 353-363
-
(2011)
Cell
, vol.144
, pp. 353-363
-
-
Basu, U.1
Meng, F.L.2
Keim, C.3
-
102
-
-
78650666372
-
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
-
Stanlie, A., M. Aida, M. Muramatsu, T. Honjo, and N. A. Begum. 2010. Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination. Proc. Natl. Acad. Sci. USA 107: 22190-22195
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22190-22195
-
-
Stanlie, A.1
Aida, M.2
Muramatsu, M.3
Honjo, T.4
Begum, N.A.5
-
103
-
-
84870204989
-
A role for the RNA pol II-associated PAF complex in AID-induced immune diversification
-
Willmann, K. L., S. Milosevic, S. Pauklin, et al. 2012. A role for the RNA pol II-associated PAF complex in AID-induced immune diversification. J. Exp. Med. 209: 2099-2111
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2099-2111
-
-
Willmann, K.L.1
Milosevic, S.2
Pauklin, S.3
-
104
-
-
78650308767
-
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
-
Yamane, A.,W. Resch, N. Kuo, et al. 2011. Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nat. Immunol. 12: 62-69
-
(2011)
Nat. Immunol.
, vol.12
, pp. 62-69
-
-
Yamane, A.1
Resch, W.2
Kuo, N.3
-
105
-
-
33748443257
-
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/-ung-/-mice
-
Xue, K., C. Rada, and M. S. Neuberger. 2006. The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/-ung-/-mice. J. Exp. Med. 203: 2085-2094
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2085-2094
-
-
Xue, K.1
Rada, C.2
Neuberger, M.S.3
-
106
-
-
79952259642
-
A single-molecule characterization of p53 search on DNA
-
Tafvizi, A., F. Huang, A. R. Fersht, L. A. Mirny, and A. M. van Oijen. 2011. A single-molecule characterization of p53 search on DNA. Proc. Natl. Acad. Sci. USA 108: 563-568
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 563-568
-
-
Tafvizi, A.1
Huang, F.2
Fersht, A.R.3
Mirny, L.A.4
Van Oijen, A.M.5
-
107
-
-
68149158825
-
S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
-
Wang, L., R. Wuerffel, S. Feldman, A. A. Khamlichi, and A. L. Kenter. 2009. S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination. J. Exp. Med. 206: 1817-1830
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1817-1830
-
-
Wang, L.1
Wuerffel, R.2
Feldman, S.3
Khamlichi, A.A.4
Kenter, A.L.5
-
108
-
-
67449161835
-
Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces da hypermutation
-
Rajagopal, D., R. W. Maul, A. Ghosh, et al. 2009. Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation. J. Exp. Med. 206: 1237-1244
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1237-1244
-
-
Rajagopal, D.1
Maul, R.W.2
Ghosh, A.3
-
111
-
-
79961150210
-
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
-
Jeevan-Raj, B. P., I. Robert, V. Heyer, et al. 2011. Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination. J. Exp. Med. 208: 1649-1660
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1649-1660
-
-
Jeevan-Raj, B.P.1
Robert, I.2
Heyer, V.3
-
112
-
-
84866564544
-
The histone chaperone SPT6 is required for AID target determination through H3K4me3 regulation
-
Begum, N. A., A. Stanlie, M. Nakata, H. Akiyama, and T. Honjo. 2012. The histone chaperone SPT6 is required for AID target determination through H3K4me3 regulation. J. Biol. Chem. 287: 32415-32429
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 32415-32429
-
-
Begum, N.A.1
Stanlie, A.2
Nakata, M.3
Akiyama, H.4
Honjo, T.5
-
113
-
-
34250773900
-
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus
-
Fraenkel, S., R. Mostoslavsky, T. I. Novobrantseva, et al. 2007. Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nat. Immunol. 8: 715-722
-
(2007)
Nat. Immunol.
, vol.8
, pp. 715-722
-
-
Fraenkel, S.1
Mostoslavsky, R.2
Novobrantseva, T.I.3
-
114
-
-
0035131689
-
Somatic hypermutation of immunoglobulin kappa transgenes: Association of mutability with demethylation
-
Jolly, C. J., and M. S. Neuberger. 2001. Somatic hypermutation of immunoglobulin kappa transgenes: association of mutability with demethylation. Immunol. Cell Biol. 79: 18-22
-
(2001)
Immunol. Cell Biol.
, vol.79
, pp. 18-22
-
-
Jolly, C.J.1
Neuberger, M.S.2
-
115
-
-
10644229388
-
Methylation protects cytidines from AID-mediated deamination
-
Larijani, M., D. Frieder, T. M. Sonbuchner, et al. 2005. Methylation protects cytidines from AID-mediated deamination. Mol. Immunol. 42: 599-604
-
(2005)
Mol. Immunol.
, vol.42
, pp. 599-604
-
-
Larijani, M.1
Frieder, D.2
Sonbuchner, T.M.3
-
116
-
-
22544443073
-
Histone modifications associated with somatic hypermutation
-
Odegard, V. H., S. T. Kim, S. M. Anderson, M. J. Shlomchik, and D. G. Schatz. 2005. Histone modifications associated with somatic hypermutation. Immunity 23: 101-110
-
(2005)
Immunity
, vol.23
, pp. 101-110
-
-
Odegard, V.H.1
Kim, S.T.2
Anderson, S.M.3
Shlomchik, M.J.4
Schatz, D.G.5
-
117
-
-
77955364172
-
Histone H2A and H2B are monoubiquitinated at AID-targeted loci
-
Borchert, G. M., N. W. Holton, K. A. Edwards, L. A. Vogel, and E. D. Larson. 2010. Histone H2A and H2B are monoubiquitinated at AID-targeted loci. PLoS One 5: e11641
-
(2010)
PLoS One
, vol.5
-
-
Borchert, G.M.1
Holton, N.W.2
Edwards, K.A.3
Vogel, L.A.4
Larson, E.D.5
-
118
-
-
62849104777
-
Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination
-
Vuong, B. Q., M. Lee, S. Kabir, et al. 2009. Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination. Nat. Immunol. 10: 420-426
-
(2009)
Nat. Immunol.
, vol.10
, pp. 420-426
-
-
Vuong, B.Q.1
Lee, M.2
Kabir, S.3
-
119
-
-
33645554975
-
Iron chelators: Correlation between effects on Plasmodium spp. and immune functions
-
Golenser, J., A. Domb, T. Mordechai-Daniel, et al. 2006. Iron chelators: correlation between effects on Plasmodium spp. and immune functions. J. Parasitol. 92: 170-177
-
(2006)
J. Parasitol.
, vol.92
, pp. 170-177
-
-
Golenser, J.1
Domb, A.2
Mordechai-Daniel, T.3
-
120
-
-
46949095793
-
Evidence for a pathogenic determinant in HIV-1 Nef involved in B cell dysfunction in HIV/AIDS
-
Swingler, S., J. Zhou, C. Swingler, et al. 2008. Evidence for a pathogenic determinant in HIV-1 Nef involved in B cell dysfunction in HIV/AIDS. Cell Host Microbe 4: 63-76
-
(2008)
Cell Host Microbe
, vol.4
, pp. 63-76
-
-
Swingler, S.1
Zhou, J.2
Swingler, C.3
-
121
-
-
0038351779
-
Common variable immunodeficiency and IgG subclass deficiency in central Alabama hemochromatosis probands homozygous for HFE C282Y
-
Barton, J. C., L. F. Bertoli, and R. T. Acton. 2003. Common variable immunodeficiency and IgG subclass deficiency in central Alabama hemochromatosis probands homozygous for HFE C282Y. Blood Cells Mol. Dis. 31: 102-111
-
(2003)
Blood Cells Mol. Dis.
, vol.31
, pp. 102-111
-
-
Barton, J.C.1
Bertoli, L.F.2
Acton, R.T.3
-
122
-
-
79956292375
-
Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2
-
Watanabe-Matsui, M., A. Muto, T. Matsui, et al. 2011. Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2. Blood 117: 5438-5448
-
(2011)
Blood
, vol.117
, pp. 5438-5448
-
-
Watanabe-Matsui, M.1
Muto, A.2
Matsui, T.3
-
123
-
-
80155198846
-
AID dysregulation in lupus-prone MRL/Fas lpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: Modulation by HoxC4
-
White, C. A., J. Seth Hawkins, E. J. Pone, et al. 2011. AID dysregulation in lupus-prone MRL/Fas lpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4. Autoimmunity 44: 585-598
-
(2011)
Autoimmunity
, vol.44
, pp. 585-598
-
-
White, C.A.1
Seth Hawkins, J.2
Pone, E.J.3
-
124
-
-
34247141537
-
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies
-
Hsu, H. C., Y. Wu, P. Yang, et al. 2007. Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. J. Immunol. 178: 5357-5365
-
(2007)
J. Immunol.
, vol.178
, pp. 5357-5365
-
-
Hsu, H.C.1
Wu, Y.2
Yang, P.3
-
125
-
-
38349178776
-
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
-
Hsu, H. C., P. Yang, J. Wang, et al. 2008. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat. Immunol. 9: 166-175
-
(2008)
Nat. Immunol.
, vol.9
, pp. 166-175
-
-
Hsu, H.C.1
Yang, P.2
Wang, J.3
-
126
-
-
79955571648
-
Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice
-
Hsu, H. C., P. Yang, Q. Wu, et al. 2011. Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. Arthritis Rheum. 63: 2038-2048
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 2038-2048
-
-
Hsu, H.C.1
Yang, P.2
Wu, Q.3
-
127
-
-
34249826624
-
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice
-
Jiang, C., J. Foley, N. Clayton, et al. 2007. Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice. J. Immunol. 178: 7422-7431
-
(2007)
J. Immunol.
, vol.178
, pp. 7422-7431
-
-
Jiang, C.1
Foley, J.2
Clayton, N.3
-
128
-
-
57449111276
-
Activationinduced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis
-
Jiang, C., M. L. Zhao, and M. Diaz. 2009. Activationinduced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis. Immunology 126: 102-113
-
(2009)
Immunology
, vol.126
, pp. 102-113
-
-
Jiang, C.1
Zhao, M.L.2
Diaz, M.3
-
129
-
-
50249179849
-
The X-files in immunity: Sex-based differences predispose immune responses
-
Fish, E. N. 2008. The X-files in immunity: sex-based differences predispose immune responses. Nat. Rev. Immunol. 8: 737-744
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 737-744
-
-
Fish, E.N.1
-
130
-
-
84861302903
-
Immune cells have sex and so should journal articles
-
Klein, S. L. 2012. Immune cells have sex and so should journal articles. Endocrinology 153: 2544-2550
-
(2012)
Endocrinology
, vol.153
, pp. 2544-2550
-
-
Klein, S.L.1
-
131
-
-
33645102445
-
Sex hormones and the genesis of autoimmunity
-
Ackerman, L. S. 2006. Sex hormones and the genesis of autoimmunity. Arch. Dermatol. 142: 371-376
-
(2006)
Arch. Dermatol.
, vol.142
, pp. 371-376
-
-
Ackerman, L.S.1
-
132
-
-
69749118434
-
Estradiol improves genital herpes vaccine efficacy in mice
-
Pennock, J. W., R. Stegall, B. Bell, et al. 2009. Estradiol improves genital herpes vaccine efficacy in mice. Vaccine 27: 5830-5836
-
(2009)
Vaccine
, vol.27
, pp. 5830-5836
-
-
Pennock, J.W.1
Stegall, R.2
Bell, B.3
-
133
-
-
0035554904
-
Sex differences in autoimmune disease
-
Whitacre, C. C. 2001. Sex differences in autoimmune disease. Nat. Immunol. 2: 777-780
-
(2001)
Nat. Immunol.
, vol.2
, pp. 777-780
-
-
Whitacre, C.C.1
-
134
-
-
77951936101
-
The Xs and y of immune responses to viral vaccines
-
Klein, S. L., A. Jedlicka, and A. Pekosz. 2010. The Xs and Y of immune responses to viral vaccines. Lancet Infect Dis. 10: 338-349
-
(2010)
Lancet Infect Dis.
, vol.10
, pp. 338-349
-
-
Klein, S.L.1
Jedlicka, A.2
Pekosz, A.3
-
135
-
-
46849085591
-
Hormonal regulation of B-cell function and systemic lupus erythematosus
-
Cohen-Solal, J. F., V. Jeganathan, L. Hill, et al. 2008. Hormonal regulation of B-cell function and systemic lupus erythematosus. Lupus 17: 528-532
-
(2008)
Lupus
, vol.17
, pp. 528-532
-
-
Cohen-Solal, J.F.1
Jeganathan, V.2
Hill, L.3
-
136
-
-
51349089115
-
Sex differences in autoimmune disease from a pathological perspective
-
Fairweather, D., S. Frisancho-Kiss, and N. R. Rose. 2008. Sex differences in autoimmune disease from a pathological perspective. Am. J. Pathol. 173: 600-609
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 600-609
-
-
Fairweather, D.1
Frisancho-Kiss, S.2
Rose, N.R.3
-
137
-
-
33744978355
-
Sex hormones and SLE: Influencing the fate of autoreactive B cells
-
Cohen-Solal, J. F., V. Jeganathan, C. M. Grimaldi, E. Peeva, and B. Diamond. 2006. Sex hormones and SLE: influencing the fate of autoreactive B cells. Curr. Top. Microbiol. Immunol. 305: 67-88
-
(2006)
Curr. Top. Microbiol. Immunol.
, vol.305
, pp. 67-88
-
-
Cohen-Solal, J.F.1
Jeganathan, V.2
Grimaldi, C.M.3
Peeva, E.4
Diamond, B.5
-
138
-
-
33746864127
-
Sex and systemic lupus erythematosus: The role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells
-
Grimaldi, C. M. 2006. Sex and systemic lupus erythematosus: the role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells. Curr. Opin. Rheumatol. 18: 456-461
-
(2006)
Curr. Opin. Rheumatol.
, vol.18
, pp. 456-461
-
-
Grimaldi, C.M.1
-
139
-
-
84858441796
-
Sex differences in spontaneous versus induced animal models of autoimmunity
-
Lee, T. P., and B. L. Chiang. 2012. Sex differences in spontaneous versus induced animal models of autoimmunity. Autoimmun. Rev. 11: A422-A429
-
(2012)
Autoimmun. Rev.
, vol.11
-
-
Lee, T.P.1
Chiang, B.L.2
-
140
-
-
34447523339
-
Estrogen receptors: How do they signal and what are their targets
-
Heldring, N., A. Pike, S. Andersson, et al. 2007. Estrogen receptors: how do they signal and what are their targets. Physiol. Rev. 87: 905-931
-
(2007)
Physiol. Rev.
, vol.87
, pp. 905-931
-
-
Heldring, N.1
Pike, A.2
Andersson, S.3
-
141
-
-
60549115641
-
Estrogen directly activates AID transcription and function
-
Pauklin, S., I. V. Sernandez, G. Bachmann, A. R. Ramiro, and S. K. Petersen-Mahrt. 2009. Estrogen directly activates AID transcription and function. J. Exp. Med. 206: 99-111
-
(2009)
J. Exp. Med.
, vol.206
, pp. 99-111
-
-
Pauklin, S.1
Sernandez, I.V.2
Bachmann, G.3
Ramiro, A.R.4
Petersen-Mahrt, S.K.5
-
142
-
-
78549245888
-
Estrogen receptors bind to and activate the promoter of the HoxC4 gene to potentiate HoxC4-mediated AID induction, immunoglobulin class-switch DNA recombination and somatic hypermutation
-
Mai, T., H. Zan, J. Zhang, et al. 2010. Estrogen receptors bind to and activate the promoter of the HoxC4 gene to potentiate HoxC4-mediated AID induction, immunoglobulin class-switch DNA recombination and somatic hypermutation. J. Biol. Chem. 285: 37797-37810
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37797-37810
-
-
Mai, T.1
Zan, H.2
Zhang, J.3
-
143
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes, I. B., and G. Schett. 2011. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365: 2205-2219
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
144
-
-
69149084624
-
Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis
-
Xu, X., H. C. Hsu, J. Chen, et al. 2009. Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis. Scand. J. Immunol. 70: 309-316
-
(2009)
Scand. J. Immunol.
, vol.70
, pp. 309-316
-
-
Xu, X.1
Hsu, H.C.2
Chen, J.3
-
145
-
-
0037881911
-
Constitutive expression of AID leads to tumorigenesis
-
Okazaki, I. M., H. Hiai, N. Kakazu, et al. 2003. Constitutive expression of AID leads to tumorigenesis. J. Exp. Med. 197: 1173-1181
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1173-1181
-
-
Okazaki, I.M.1
Hiai, H.2
Kakazu, N.3
-
146
-
-
33747869927
-
AID mutates a non-immunoglobulin transgene independent of chromosomal position
-
Parsa, J. Y., W. Basit, C. L.Wang, et al. 2007. AID mutates a non-immunoglobulin transgene independent of chromosomal position. Mol. Immunol. 44: 567-575
-
(2007)
Mol. Immunol.
, vol.44
, pp. 567-575
-
-
Parsa, J.Y.1
Basit, W.2
Wang, L.C.3
-
147
-
-
34249015960
-
Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells
-
Feldhahn, N., N. Henke, K. Melchior, et al. 2007. Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells. J. Exp. Med. 204: 1157-1166
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1157-1166
-
-
Feldhahn, N.1
Henke, N.2
Melchior, K.3
-
148
-
-
77952583868
-
Preventing AID, a physiological mutator, from deleterious activation: Regulation of the genomic instability that is associated with antibody diversity
-
Nagaoka, H., T. H. Tran, M. Kobayashi, M. Aida, and T. Honjo. 2010. Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity. Int. Immunol. 22: 227-235
-
(2010)
Int. Immunol.
, vol.22
, pp. 227-235
-
-
Nagaoka, H.1
Tran, T.H.2
Kobayashi, M.3
Aida, M.4
Honjo, T.5
-
149
-
-
84555203265
-
Activationinduced cytidine deaminase expression in CD4 T cells is associated with a unique IL-10-producing subset that increases with age
-
Qin, H., K. Suzuki, M. Nakata, et al. 2011. Activationinduced cytidine deaminase expression in CD4 T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One 6: e29141
-
(2011)
PLoS One
, vol.6
-
-
Qin, H.1
Suzuki, K.2
Nakata, M.3
-
150
-
-
33750022561
-
Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma
-
Rossi, D., E. Berra, M. Cerri, et al. 2006. Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma. Haematologica 91: 1405-1409
-
(2006)
Haematologica
, vol.91
, pp. 1405-1409
-
-
Rossi, D.1
Berra, E.2
Cerri, M.3
-
151
-
-
59449102152
-
Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes
-
Casellas, R., A. Yamane, A. L. Kovalchuk, and M. Potter. 2009. Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes. Immunology 126: 316-328
-
(2009)
Immunology
, vol.126
, pp. 316-328
-
-
Casellas, R.1
Yamane, A.2
Kovalchuk, A.L.3
Potter, M.4
-
152
-
-
69249236962
-
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia
-
Klemm, L., C. Duy, I. Iacobucci, et al. 2009. The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell 16: 232-245
-
(2009)
Cancer Cell
, vol.16
, pp. 232-245
-
-
Klemm, L.1
Duy, C.2
Iacobucci, I.3
-
153
-
-
69249241826
-
Imatinib resistance and progression of CML to blast crisis: Somatic hypermutation AIDing the way
-
Strout, M. P., and D. G. Schatz. 2009. Imatinib resistance and progression of CML to blast crisis: somatic hypermutation AIDing the way. Cancer Cell 16: 174-176
-
(2009)
Cancer Cell
, vol.16
, pp. 174-176
-
-
Strout, M.P.1
Schatz, D.G.2
-
154
-
-
36949015428
-
Oncogenic events triggered by AID, the adverse effect of antibody diversification
-
Pérez-Durán, P., V. G. de Yebenes, and A. R. Ramiro. 2007. Oncogenic events triggered by AID, the adverse effect of antibody diversification. Carcinogenesis 28: 2427-2433
-
(2007)
Carcinogenesis
, vol.28
, pp. 2427-2433
-
-
Pérez-Durán, P.1
De Yebenes, V.G.2
Ramiro, A.R.3
-
156
-
-
78649688865
-
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer
-
Matsumoto, Y., H. Marusawa, K. Kinoshita, et al. 2010. Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer. Gastroenterology 139: 1984-1994
-
(2010)
Gastroenterology
, vol.139
, pp. 1984-1994
-
-
Matsumoto, Y.1
Marusawa, H.2
Kinoshita, K.3
-
157
-
-
78651348687
-
Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers
-
Endo, Y., H. Marusawa, and T. Chiba. 2011. Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers. J. Gastroenterol. 46(Suppl 1): 6-10
-
(2011)
J. Gastroenterol.
, vol.46
, Issue.SUPPL. 1
, pp. 6-10
-
-
Endo, Y.1
Marusawa, H.2
Chiba, T.3
-
158
-
-
80051546278
-
Aberrant expression and mutationinducing activity of AID in human lung cancer
-
Shinmura, K., H. Igarashi, M. Goto, et al. 2011. Aberrant expression and mutationinducing activity of AID in human lung cancer. Ann. Surg. Oncol. 18: 2084-2092
-
(2011)
Ann. Surg. Oncol.
, vol.18
, pp. 2084-2092
-
-
Shinmura, K.1
Igarashi, H.2
Goto, M.3
-
159
-
-
33646269045
-
Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines
-
Babbage, G., C. H. Ottensmeier, J. Blaydes, F. K. Stevenson, and S. S. Sahota. 2006. Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines. Cancer Res. 66: 99-111
-
(2006)
Cancer Res.
, vol.66
, pp. 99-111
-
-
Babbage, G.1
Ottensmeier, C.H.2
Blaydes, J.3
Stevenson, F.K.4
Sahota, S.S.5
-
160
-
-
30344472683
-
MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells
-
Macduff, D. A., M. S. Neuberger, and R. S. Harris. 2006. MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells. Mol. Immunol. 43: 1099-1108
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1099-1108
-
-
MacDuff, D.A.1
Neuberger, M.S.2
Harris, R.S.3
-
161
-
-
77955385274
-
The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination
-
Demorest, Z. L., D. A. MacDuff, W. L. Brown, et al. 2010. The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination. PLoS One 5: e11660
-
(2010)
PLoS One
, vol.5
-
-
Demorest, Z.L.1
MacDuff, D.A.2
Brown, W.L.3
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