메뉴 건너뛰기




Volumn 2, Issue 5, 2012, Pages 1220-1232

Rev1 Recruits Ung to Switch Regions and Enhances dU Glycosylation for Immunoglobulin Class Switch DNA Recombination

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; DEOXYURIDINE; DNA POLYMERASE REV1; PROTEIN MSH2; URACIL DNA GLYCOSIDASE;

EID: 84870427871     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.09.029     Document Type: Article
Times cited : (35)

References (50)
  • 1
    • 62449164136 scopus 로고    scopus 로고
    • Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
    • Begum N.A., Stanlie A., Doi T., Sasaki Y., Jin H.W., Kim Y.S., Nagaoka H., Honjo T. Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination. Proc. Natl. Acad. Sci. USA 2009, 106:2752-2757.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2752-2757
    • Begum, N.A.1    Stanlie, A.2    Doi, T.3    Sasaki, Y.4    Jin, H.W.5    Kim, Y.S.6    Nagaoka, H.7    Honjo, T.8
  • 2
    • 33745498089 scopus 로고    scopus 로고
    • DNA repair in antibody somatic hypermutation
    • Casali P., Pal Z., Xu Z., Zan H. DNA repair in antibody somatic hypermutation. Trends Immunol. 2006, 27:313-321.
    • (2006) Trends Immunol. , vol.27 , pp. 313-321
    • Casali, P.1    Pal, Z.2    Xu, Z.3    Zan, H.4
  • 3
    • 18244401095 scopus 로고    scopus 로고
    • Contribution of DNA polymerase η to immunoglobulin gene hypermutation in the mouse
    • Delbos F., De Smet A., Faili A., Aoufouchi S., Weill J.C., Reynaud C.A. Contribution of DNA polymerase η to immunoglobulin gene hypermutation in the mouse. J. Exp. Med. 2005, 201:1191-1196.
    • (2005) J. Exp. Med. , vol.201 , pp. 1191-1196
    • Delbos, F.1    De Smet, A.2    Faili, A.3    Aoufouchi, S.4    Weill, J.C.5    Reynaud, C.A.6
  • 4
    • 0037026482 scopus 로고    scopus 로고
    • Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
    • Di Noia J., Neuberger M.S. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature 2002, 419:43-48.
    • (2002) Nature , vol.419 , pp. 43-48
    • Di Noia, J.1    Neuberger, M.S.2
  • 7
    • 33344468484 scopus 로고    scopus 로고
    • Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice
    • Jansen J.G., Langerak P., Tsaalbi-Shtylik A., van den Berk P., Jacobs H., de Wind N. Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice. J. Exp. Med. 2006, 203:319-323.
    • (2006) J. Exp. Med. , vol.203 , pp. 319-323
    • Jansen, J.G.1    Langerak, P.2    Tsaalbi-Shtylik, A.3    van den Berk, P.4    Jacobs, H.5    de Wind, N.6
  • 8
    • 4744337615 scopus 로고    scopus 로고
    • The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination
    • Kim E.C., Edmonston C.R., Wu X., Schaffer A., Casali P. The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination. J. Biol. Chem. 2004, 279:42258-42269.
    • (2004) J. Biol. Chem. , vol.279 , pp. 42258-42269
    • Kim, E.C.1    Edmonston, C.R.2    Wu, X.3    Schaffer, A.4    Casali, P.5
  • 9
    • 33845730352 scopus 로고    scopus 로고
    • AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner
    • Larijani M., Petrov A.P., Kolenchenko O., Berru M., Krylov S.N., Martin A. AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner. Mol. Cell. Biol. 2007, 27:20-30.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 20-30
    • Larijani, M.1    Petrov, A.P.2    Kolenchenko, O.3    Berru, M.4    Krylov, S.N.5    Martin, A.6
  • 10
    • 63149179802 scopus 로고    scopus 로고
    • Balancing AID and DNA repair during somatic hypermutation
    • Liu M., Schatz D.G. Balancing AID and DNA repair during somatic hypermutation. Trends Immunol. 2009, 30:173-181.
    • (2009) Trends Immunol. , vol.30 , pp. 173-181
    • Liu, M.1    Schatz, D.G.2
  • 11
    • 78549245888 scopus 로고    scopus 로고
    • Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation
    • Mai T., Zan H., Zhang J., Hawkins J.S., Xu Z., Casali P. Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation. J. Biol. Chem. 2010, 285:37797-37810.
    • (2010) J. Biol. Chem. , vol.285 , pp. 37797-37810
    • Mai, T.1    Zan, H.2    Zhang, J.3    Hawkins, J.S.4    Xu, Z.5    Casali, P.6
  • 12
    • 68149178379 scopus 로고    scopus 로고
    • A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation
    • Masuda K., Ouchida R., Li Y., Gao X., Mori H., Wang J.Y. A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation. J. Immunol. 2009, 183:1846-1850.
    • (2009) J. Immunol. , vol.183 , pp. 1846-1850
    • Masuda, K.1    Ouchida, R.2    Li, Y.3    Gao, X.4    Mori, H.5    Wang, J.Y.6
  • 13
    • 77953962524 scopus 로고    scopus 로고
    • Controlling somatic hypermutation in immunoglobulin variable and switch regions
    • Maul R.W., Gearhart P.J. Controlling somatic hypermutation in immunoglobulin variable and switch regions. Immunol. Res. 2010, 47:113-122.
    • (2010) Immunol. Res. , vol.47 , pp. 113-122
    • Maul, R.W.1    Gearhart, P.J.2
  • 15
    • 25844440534 scopus 로고    scopus 로고
    • Rev1 employs a novel mechanism of DNA synthesis using a protein template
    • Nair D.T., Johnson R.E., Prakash L., Prakash S., Aggarwal A.K. Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science 2005, 309:2219-2222.
    • (2005) Science , vol.309 , pp. 2219-2222
    • Nair, D.T.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4    Aggarwal, A.K.5
  • 16
    • 33846415063 scopus 로고    scopus 로고
    • Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T
    • Neuberger M.S., Rada C. Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T. J. Exp. Med. 2007, 204:7-10.
    • (2007) J. Exp. Med. , vol.204 , pp. 7-10
    • Neuberger, M.S.1    Rada, C.2
  • 19
  • 20
    • 78649404299 scopus 로고    scopus 로고
    • Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90
    • Orthwein A., Patenaude A.M., Affar B., Lamarre A., Young J.C., Di Noia J.M. Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90. J. Exp. Med. 2010, 207:2751-2765.
    • (2010) J. Exp. Med. , vol.207 , pp. 2751-2765
    • Orthwein, A.1    Patenaude, A.M.2    Affar, B.3    Lamarre, A.4    Young, J.C.5    Di Noia, J.M.6
  • 21
    • 25844466570 scopus 로고    scopus 로고
    • Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo
    • Otsuka C., Kunitomi N., Iwai S., Loakes D., Negishi K. Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo. Mutat. Res. 2005, 578:79-87.
    • (2005) Mutat. Res. , vol.578 , pp. 79-87
    • Otsuka, C.1    Kunitomi, N.2    Iwai, S.3    Loakes, D.4    Negishi, K.5
  • 22
    • 67349090990 scopus 로고    scopus 로고
    • HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation
    • Park S.R., Zan H., Pal Z., Zhang J., Al-Qahtani A., Pone E.J., Xu Z., Mai T., Casali P. HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nat. Immunol. 2009, 10:540-550.
    • (2009) Nat. Immunol. , vol.10 , pp. 540-550
    • Park, S.R.1    Zan, H.2    Pal, Z.3    Zhang, J.4    Al-Qahtani, A.5    Pone, E.J.6    Xu, Z.7    Mai, T.8    Casali, P.9
  • 23
    • 84860311836 scopus 로고    scopus 로고
    • B cell TLRs and induction of immunoglobulin class-switch DNA recombination
    • Pone E.J., Xu Z., White C.A., Zan H., Casali P. B cell TLRs and induction of immunoglobulin class-switch DNA recombination. Front. Biosci. 2012, 17:2594-2615.
    • (2012) Front. Biosci. , vol.17 , pp. 2594-2615
    • Pone, E.J.1    Xu, Z.2    White, C.A.3    Zan, H.4    Casali, P.5
  • 24
    • 84860292969 scopus 로고    scopus 로고
    • BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway
    • Pone E.J., Zhang J., Mai T., White C.A., Li G., Sakakura J.K., Patel P.J., Al-Qahtani A., Zan H., Xu Z., Casali P. BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway. Nat. Commun. 2012, 3:767.
    • (2012) Nat. Commun. , vol.3 , pp. 767
    • Pone, E.J.1    Zhang, J.2    Mai, T.3    White, C.A.4    Li, G.5    Sakakura, J.K.6    Patel, P.J.7    Al-Qahtani, A.8    Zan, H.9    Xu, Z.10    Casali, P.11
  • 25
    • 21244506437 scopus 로고    scopus 로고
    • Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function
    • Prakash S., Johnson R.E., Prakash L. Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu. Rev. Biochem. 2005, 74:317-353.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 317-353
    • Prakash, S.1    Johnson, R.E.2    Prakash, L.3
  • 26
    • 0037108463 scopus 로고    scopus 로고
    • Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
    • Rada C., Williams G.T., Nilsen H., Barnes D.E., Lindahl T., Neuberger M.S. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 2002, 12:1748-1755.
    • (2002) Curr. Biol. , vol.12 , pp. 1748-1755
    • Rada, C.1    Williams, G.T.2    Nilsen, H.3    Barnes, D.E.4    Lindahl, T.5    Neuberger, M.S.6
  • 27
    • 6344256944 scopus 로고    scopus 로고
    • Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
    • Rada C., Di Noia J.M., Neuberger M.S. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 2004, 16:163-171.
    • (2004) Mol. Cell , vol.16 , pp. 163-171
    • Rada, C.1    Di Noia, J.M.2    Neuberger, M.S.3
  • 28
  • 29
    • 14844362615 scopus 로고    scopus 로고
    • Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1
    • Ross A.L., Simpson L.J., Sale J.E. Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1. Nucleic Acids Res. 2005, 33:1280-1289.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 1280-1289
    • Ross, A.L.1    Simpson, L.J.2    Sale, J.E.3
  • 30
    • 0038515309 scopus 로고    scopus 로고
    • E-proteins directly regulate expression of activation-induced deaminase in mature B cells
    • Sayegh C.E., Quong M.W., Agata Y., Murre C. E-proteins directly regulate expression of activation-induced deaminase in mature B cells. Nat. Immunol. 2003, 4:586-593.
    • (2003) Nat. Immunol. , vol.4 , pp. 586-593
    • Sayegh, C.E.1    Quong, M.W.2    Agata, Y.3    Murre, C.4
  • 31
    • 0038157392 scopus 로고    scopus 로고
    • Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements
    • Schaffer A., Kim E.C., Wu X., Zan H., Testoni L., Salamon S., Cerutti A., Casali P. Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. J. Biol. Chem. 2003, 278:23141-23150.
    • (2003) J. Biol. Chem. , vol.278 , pp. 23141-23150
    • Schaffer, A.1    Kim, E.C.2    Wu, X.3    Zan, H.4    Testoni, L.5    Salamon, S.6    Cerutti, A.7    Casali, P.8
  • 32
    • 63049129975 scopus 로고    scopus 로고
    • Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability
    • Schenten D., Kracker S., Esposito G., Franco S., Klein U., Murphy M., Alt F.W., Rajewsky K. Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability. J. Exp. Med. 2009, 206:477-490.
    • (2009) J. Exp. Med. , vol.206 , pp. 477-490
    • Schenten, D.1    Kracker, S.2    Esposito, G.3    Franco, S.4    Klein, U.5    Murphy, M.6    Alt, F.W.7    Rajewsky, K.8
  • 33
    • 80053044268 scopus 로고    scopus 로고
    • The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/REV1-dependent translesion DNA synthesis
    • Sharma N.M., Kochenova O.V., Shcherbakova P.V. The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/REV1-dependent translesion DNA synthesis. J. Biol. Chem. 2011, 286:33557-33566.
    • (2011) J. Biol. Chem. , vol.286 , pp. 33557-33566
    • Sharma, N.M.1    Kochenova, O.V.2    Shcherbakova, P.V.3
  • 35
    • 79955632686 scopus 로고    scopus 로고
    • Complex regulation and function of activation-induced cytidine deaminase
    • Stavnezer J. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol. 2011, 32:194-201.
    • (2011) Trends Immunol. , vol.32 , pp. 194-201
    • Stavnezer, J.1
  • 36
  • 37
    • 68149158825 scopus 로고    scopus 로고
    • S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
    • Wang L., Wuerffel R., Feldman S., Khamlichi A.A., Kenter A.L. S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination. J. Exp. Med. 2009, 206:1817-1830.
    • (2009) J. Exp. Med. , vol.206 , pp. 1817-1830
    • Wang, L.1    Wuerffel, R.2    Feldman, S.3    Khamlichi, A.A.4    Kenter, A.L.5
  • 38
    • 41149153412 scopus 로고    scopus 로고
    • DNA polymerases in adaptive immunity
    • Weill J.C., Reynaud C.A. DNA polymerases in adaptive immunity. Nat. Rev. Immunol. 2008, 8:302-312.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 302-312
    • Weill, J.C.1    Reynaud, C.A.2
  • 40
    • 34447279017 scopus 로고    scopus 로고
    • DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
    • Wu X., Stavnezer J. DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination. J. Exp. Med. 2007, 204:1677-1689.
    • (2007) J. Exp. Med. , vol.204 , pp. 1677-1689
    • Wu, X.1    Stavnezer, J.2
  • 41
    • 78650580818 scopus 로고    scopus 로고
    • Error-prone translesion synthesis mediates acquired chemoresistance
    • Xie K., Doles J., Hemann M.T., Walker G.C. Error-prone translesion synthesis mediates acquired chemoresistance. Proc. Natl. Acad. Sci. USA 2010, 107:20792-20797.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 20792-20797
    • Xie, K.1    Doles, J.2    Hemann, M.T.3    Walker, G.C.4
  • 43
    • 84862865669 scopus 로고    scopus 로고
    • Immunoglobulin class-switch DNA recombination: induction, targeting and beyond
    • Xu Z., Zan H., Pone E.J., Mai T., Casali P. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nat. Rev. Immunol. 2012, 12:517-531.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 517-531
    • Xu, Z.1    Zan, H.2    Pone, E.J.3    Mai, T.4    Casali, P.5
  • 44
    • 52949100601 scopus 로고    scopus 로고
    • AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID
    • Zan H., Casali P. AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Mol. Immunol. 2008, 46:45-61.
    • (2008) Mol. Immunol. , vol.46 , pp. 45-61
    • Zan, H.1    Casali, P.2
  • 45
    • 0033559138 scopus 로고    scopus 로고
    • Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation
    • Zan H., Cerutti A., Dramitinos P., Schaffer A., Li Z., Casali P. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation. J. Immunol. 1999, 162:3437-3447.
    • (1999) J. Immunol. , vol.162 , pp. 3437-3447
    • Zan, H.1    Cerutti, A.2    Dramitinos, P.3    Schaffer, A.4    Li, Z.5    Casali, P.6
  • 46
    • 0034662044 scopus 로고    scopus 로고
    • B cell receptor engagement and T cell contact induce Bcl-6 hypermutation in human B cells: identity with Ig hypermutation
    • Zan H., Li Z., Yamaji K., Dramitinos P., Cerutti A., Casali P. B cell receptor engagement and T cell contact induce Bcl-6 hypermutation in human B cells: identity with Ig hypermutation. J. Immunol. 2000, 165:830-839.
    • (2000) J. Immunol. , vol.165 , pp. 830-839
    • Zan, H.1    Li, Z.2    Yamaji, K.3    Dramitinos, P.4    Cerutti, A.5    Casali, P.6
  • 47
    • 0035005241 scopus 로고    scopus 로고
    • The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation
    • Zan H., Komori A., Li Z., Cerutti A., Schaffer A., Flajnik M.F., Diaz M., Casali P. The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation. Immunity 2001, 14:643-653.
    • (2001) Immunity , vol.14 , pp. 643-653
    • Zan, H.1    Komori, A.2    Li, Z.3    Cerutti, A.4    Schaffer, A.5    Flajnik, M.F.6    Diaz, M.7    Casali, P.8
  • 48
    • 0038771252 scopus 로고    scopus 로고
    • AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation
    • Zan H., Wu X., Komori A., Holloman W.K., Casali P. AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation. Immunity 2003, 18:727-738.
    • (2003) Immunity , vol.18 , pp. 727-738
    • Zan, H.1    Wu, X.2    Komori, A.3    Holloman, W.K.4    Casali, P.5
  • 49
    • 27744483444 scopus 로고    scopus 로고
    • The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation
    • Zan H., Shima N., Xu Z., Al-Qahtani A., Evinger Iii A.J., Zhong Y., Schimenti J.C., Casali P. The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J. 2005, 24:3757-3769.
    • (2005) EMBO J. , vol.24 , pp. 3757-3769
    • Zan, H.1    Shima, N.2    Xu, Z.3    Al-Qahtani, A.4    Evinger Iii, A.J.5    Zhong, Y.6    Schimenti, J.C.7    Casali, P.8
  • 50
    • 0036529562 scopus 로고    scopus 로고
    • Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion
    • Zhang Y., Wu X., Rechkoblit O., Geacintov N.E., Taylor J.S., Wang Z. Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Nucleic Acids Res. 2002, 30:1630-1638.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1630-1638
    • Zhang, Y.1    Wu, X.2    Rechkoblit, O.3    Geacintov, N.E.4    Taylor, J.S.5    Wang, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.