메뉴 건너뛰기




Volumn 2, Issue 2, 2012, Pages 87-106

Studies of depression-related states in animal models of parkinsonism

Author keywords

anhedonia; dopamine; neurogenesis; Parkinson's disease; serotonin

Indexed keywords

1 METHYL 4 PHENYLTETRAHYDROPIRIDINE; 4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ADENOSINE; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; GLUTAMIC ACID; INDUSTRIAL TOXIC SUBSTANCE; MONOAMINE OXIDASE INHIBITOR; NEUROTRANSMITTER; NORADRENALIN; OXIDOPAMINE; RESERPINE; ROTENONE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84864697183     PISSN: 18777171     EISSN: 1877718X     Source Type: Journal    
DOI: 10.3233/JPD-2012-12076     Document Type: Review
Times cited : (17)

References (233)
  • 1
    • 0032946784 scopus 로고    scopus 로고
    • Incidence and distribution of parkinsonism in Olmsted County Minnesota 1976-1990
    • Bower JH, Maraganore DM, McDonnell SK, & Rocca WA (1999) Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990. Neurology, 52, 1214-1220.
    • (1999) Neurology , vol.52 , pp. 1214-1220
    • Bower, J.H.1    Maraganore, D.M.2    McDonnell, S.K.3    Rocca, W.A.4
  • 2
    • 67649506191 scopus 로고    scopus 로고
    • Tests to assess motor phenotype in mice: A user's guide
    • Brooks SP, & Dunnett SB (2009) Tests to assess motor phenotype in mice: A user's guide. Nat Rev Neurosci, 10, 519-529.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 519-529
    • Brooks, S.P.1    Dunnett, S.B.2
  • 3
    • 33748300291 scopus 로고    scopus 로고
    • Behavioral models of Parkinson's disease in rodents: A new look at an old problem
    • Meredith GE, & Kang UJ (2006) Behavioral models of Parkinson's disease in rodents: A new look at an old problem. Mov Disord, 21, 1595-1606.
    • (2006) Mov. Disord. , vol.21 , pp. 1595-1606
    • Meredith, G.E.1    Kang, U.J.2
  • 7
    • 0026582759 scopus 로고
    • Depression and Parkinson's disease: A review
    • Cummings JL (1992) Depression and Parkinson's disease: A review. Am J Psychiatry, 149, 443-454.
    • (1992) Am. J. Psychiatry , vol.149 , pp. 443-454
    • Cummings, J.L.1
  • 8
    • 34250328819 scopus 로고    scopus 로고
    • Differential effects on forelimb grasping behavior induced by fetal dopaminergic grafts in hemiparkinsonian rats
    • Klein A, Metz GA, Papazoglou A, & Nikkhah G (2007) Differential effects on forelimb grasping behavior induced by fetal dopaminergic grafts in hemiparkinsonian rats. Neurobiol Dis, 27, 24-35.
    • (2007) Neurobiol. Dis. , vol.27 , pp. 24-35
    • Klein, A.1    Metz, G.A.2    Papazoglou, A.3    Nikkhah, G.4
  • 9
    • 34250647416 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease
    • Pinna A, Pontis S, Borsini F, & Morelli M (2007) Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease. Synapse, 61, 606-614.
    • (2007) Synapse , vol.61 , pp. 606-614
    • Pinna, A.1    Pontis, S.2    Borsini, F.3    Morelli, M.4
  • 10
    • 70449526441 scopus 로고    scopus 로고
    • Progressive dopaminergic degeneration in the chronic MPTPp mouse model of Parkinson's disease
    • Schintu N, Frau L, Ibba M, Garau A, Carboni E, & Carta AR (2009) Progressive dopaminergic degeneration in the chronic MPTPp mouse model of Parkinson's disease. Neurotox Res, 16, 127-139.
    • (2009) Neurotox. Res. , vol.16 , pp. 127-139
    • Schintu, N.1    Frau, L.2    Ibba, M.3    Garau, A.4    Carboni, E.5    Carta, A.R.6
  • 11
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler EJ, & Hyman SE (2010) Animal models of neuropsychiatric disorders. Nat Neurosci, 13, 1161-1169.
    • (2010) Nat. Neurosci. , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 12
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • Porsolt RD, Le Pichon M, & Jalfre M (1977) Depression: A new animal model sensitive to antidepressant treatments. Nature, 266, 730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 13
    • 77952229468 scopus 로고    scopus 로고
    • Rodent models in depression research: Classical strategies and newdirections
    • Pollak DD, Rey CE, & Monje FJ (2010) Rodent models in depression research: Classical strategies and newdirections. Ann Med, 42, 252-264.
    • (2010) Ann. Med. , vol.42 , pp. 252-264
    • Pollak, D.D.1    Rey, C.E.2    Monje, F.J.3
  • 15
    • 0029081299 scopus 로고
    • Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
    • Detke MJ, Rickels M, & Lucki I (1995) Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology (Berl), 121, 66-72.
    • (1995) Psychopharmacology (Berl. , vol.121 , pp. 66-72
    • Detke, M.J.1    Rickels, M.2    Lucki, I.3
  • 16
    • 0021990491 scopus 로고
    • The tail suspension test:Anewmethod for screening antidepressants in mice
    • Steru L, Chermat R, Thierry B, & Simon P (1985) The tail suspension test:Anewmethod for screening antidepressants in mice. Psychopharmacology (Berl), 85, 367-370.
    • (1985) Psychopharmacology (Berl. , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 17
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: Recent developments and future needs
    • Cryan JF, Markou A, & Lucki I (2002) Assessing antidepressant activity in rodents: Recent developments and future needs. Trends Pharmacol Sci, 23, 238-245.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 18
    • 0035312635 scopus 로고    scopus 로고
    • Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice
    • Liu X, & Gershenfeld HK (2001) Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice. Biol Psychiatry, 49, 575-581.
    • (2001) Biol. Psychiatry , vol.49 , pp. 575-581
    • Liu, X.1    Gershenfeld, H.K.2
  • 19
    • 2942662069 scopus 로고    scopus 로고
    • Effects of chronic fluoxetine in animal models of anxiety and depression
    • Dulawa SC, Holick KA, Gundersen B, & Hen R (2004) Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology, 29, 1321-1330.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1321-1330
    • Dulawa, S.C.1    Holick, K.A.2    Gundersen, B.3    Hen, R.4
  • 20
    • 19844379585 scopus 로고    scopus 로고
    • Recent advances in animal models of chronic antidepressant effects: The noveltyinduced hypophagia test
    • Dulawa SC, & Hen R (2005) Recent advances in animal models of chronic antidepressant effects: The noveltyinduced hypophagia test. Neurosci Biobehav Rev, 29, 771-783.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 771-783
    • Dulawa, S.C.1    Hen, R.2
  • 21
    • 70350756640 scopus 로고    scopus 로고
    • Mental disorders
    • (Fauci, A., ed) McGraw-Hill Medical
    • Reus V (2008) Mental disorders. In Harrison's Principles of Internal Medicine (Fauci, A., ed), McGraw-Hill Medical, pp. 2710-2723.
    • (2008) Harrison's Principles of Internal Medicine , pp. 2710-2723
    • Reus, V.1
  • 22
    • 33747037628 scopus 로고    scopus 로고
    • Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression
    • Jayatissa MN, Bisgaard C, Tingstrom A, Papp M, & Wiborg O (2006) Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Neuropsychopharmacology, 31, 2395-2404.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2395-2404
    • Jayatissa, M.N.1    Bisgaard, C.2    Tingstrom, A.3    Papp, M.4    Wiborg, O.5
  • 23
    • 33846837326 scopus 로고    scopus 로고
    • Evaluation of reward processes in an animal model of depression
    • Slattery DA, Markou A, & Cryan JF (2007) Evaluation of reward processes in an animal model of depression. Psychopharmacology (Berl), 190, 555-568.
    • (2007) Psychopharmacology (Berl. , vol.190 , pp. 555-568
    • Slattery, D.A.1    Markou, A.2    Cryan, J.F.3
  • 24
    • 0026831589 scopus 로고
    • Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats
    • Moreau JL, Jenck F, Martin JR, Mortas P, & Haefely WE (1992) Antidepressant treatment prevents chronic unpredictable mild stress-induced anhedonia as assessed by ventral tegmentum self-stimulation behavior in rats. Eur Neuropsychopharmacol, 2, 43-49.
    • (1992) Eur. Neuropsychopharmacol. , vol.2 , pp. 43-49
    • Moreau, J.L.1    Jenck, F.2    Martin, J.R.3    Mortas, P.4    Haefely, W.E.5
  • 26
    • 23844500078 scopus 로고    scopus 로고
    • Chronic mild stress (CMS) revisited: Consistency and behavioural- neurobiological concordance in the effects of CMS
    • Willner P (2005) Chronic mild stress (CMS) revisited: Consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology, 52, 90-110.
    • (2005) Neuropsychobiology , vol.52 , pp. 90-110
    • Willner, P.1
  • 29
    • 19944391381 scopus 로고    scopus 로고
    • The olfactory bulbectomised rat as a model of depression
    • Song C, & Leonard BE (2005) The olfactory bulbectomised rat as a model of depression. Neurosci Biobehav Rev, 29, 627-647.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 627-647
    • Song, C.1    Leonard, B.E.2
  • 30
    • 0014376793 scopus 로고
    • 6-Hydroxy-dopamine induced degeneration of central monoamine neurons
    • Ungerstedt U (1968) 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol, 5, 107-110.
    • (1968) Eur. J. Pharmacol. , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 32
    • 0029981267 scopus 로고    scopus 로고
    • Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat
    • Lee CS, Sauer H,&Bjorklund A (1996) Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience, 72, 641-653.
    • (1996) Neuroscience , vol.72 , pp. 641-653
    • Lee, C.S.1    Sauer, H.2    Bjorklund, A.3
  • 33
    • 48349148611 scopus 로고    scopus 로고
    • Nonmotor symptoms in Parkinson's disease: Investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model
    • Branchi I, D'Andrea I, Armida M, Cassano T, Pezzola A, Potenza RL, Morgese MG, Popoli P, & Alleva E (2008) Nonmotor symptoms in Parkinson's disease: Investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model. J Neurosci Res, 86, 2050-2061.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 2050-2061
    • Branchi, I.1    D'Andrea, I.2    Armida, M.3    Cassano, T.4    Pezzola, A.5    Potenza, R.L.6    Morgese, M.G.7    Popoli, P.8    Alleva, E.9
  • 34
    • 78649907182 scopus 로고    scopus 로고
    • Potential mechanisms underlying anxiety and depression in Parkinson's disease: Consequences of l-DOPA treatment
    • Eskow Jaunarajs KL, Angoa-Perez M, Kuhn DM, & Bishop C (2011) Potential mechanisms underlying anxiety and depression in Parkinson's disease: Consequences of l-DOPA treatment. Neurosci Biobehav Rev, 35, 556-564.
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , pp. 556-564
    • Eskow Jaunarajs, K.L.1    Angoa-Perez, M.2    Kuhn, D.M.3    Bishop, C.4
  • 35
    • 82955249032 scopus 로고    scopus 로고
    • Antidepressant-like properties of sarizotan in experimental Parkinsonism
    • Zhang X, Egeland M, & Svenningsson P (2011) Antidepressant-like properties of sarizotan in experimental Parkinsonism. Psychopharmacology (Berl), 218, 621-634.
    • (2011) Psychopharmacology (Berl. , vol.218 , pp. 621-634
    • Zhang, X.1    Egeland, M.2    Svenningsson, P.3
  • 36
    • 77955057715 scopus 로고    scopus 로고
    • Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine
    • Santiago RM, Barbieiro J, Lima MM, Dombrowski PA, Andreatini R,&VitalMA(2010) Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine. Prog Neuropsychopharmacol Biol Psychiatry, 34, 1104-1114.
    • (2010) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.34 , pp. 1104-1114
    • Santiago, R.M.1    Barbieiro, J.2    Lima, M.M.3    Dombrowski, P.A.4    Andreatini, R.5    Vital, M.A.6
  • 37
    • 34848892098 scopus 로고    scopus 로고
    • Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats
    • Winter C, von Rumohr A, Mundt A, Petrus D, Klein J, Lee T, Morgenstern R, Kupsch A, & Juckel G (2007) Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats. Behav Brain Res, 184, 133-141.
    • (2007) Behav. Brain Res. , vol.184 , pp. 133-141
    • Winter, C.1    Von Rumohr, A.2    Mundt, A.3    Petrus, D.4    Klein, J.5    Lee, T.6    Morgenstern, R.7    Kupsch, A.8    Juckel, G.9
  • 38
    • 77955383138 scopus 로고    scopus 로고
    • Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease
    • Dunnett SB,&LelosM(2010) Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease. Prog Brain Res, 184, 35-51.
    • (2010) Prog. Brain Res. , vol.184 , pp. 35-51
    • Dunnett, S.B.1    Lelos, M.2
  • 39
    • 0025330367 scopus 로고
    • Evaluation of a 1-methyl-4-phenyl-1 2 3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism
    • Arai N, Misugi K, Goshima Y, & Misu Y (1990) Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism. Brain Res, 515, 57-63.
    • (1990) Brain Res. , vol.515 , pp. 57-63
    • Arai, N.1    Misugi, K.2    Goshima, Y.3    Misu, Y.4
  • 40
    • 0030692667 scopus 로고    scopus 로고
    • MPTPinduced deficits in motor activity: Neuroprotective effects of the spintrapping agent, alpha-phenyl-tert-butyl-nitrone (PBN)
    • Fredriksson A, Eriksson P, & Archer T (1997) MPTPinduced deficits in motor activity: Neuroprotective effects of the spintrapping agent, alpha-phenyl-tert-butyl-nitrone (PBN). J Neural Transm, 104, 579-592.
    • (1997) J. Neural. Transm. , vol.104 , pp. 579-592
    • Fredriksson, A.1    Eriksson, P.2    Archer, T.3
  • 41
    • 0023131195 scopus 로고
    • Histochemical, biochemical and behavioural consequences of MPTP treatment in C-57 black mice
    • Willis GL, & Donnan GA (1987) Histochemical, biochemical and behavioural consequences of MPTP treatment in C-57 black mice. Brain Res, 402, 269-274.
    • (1987) Brain Res. , vol.402 , pp. 269-274
    • Willis, G.L.1    Donnan, G.A.2
  • 42
    • 0026012021 scopus 로고
    • Destruction of norepinephrine terminals in 1-methyl-4-phenyl-1 2 3,6-tetrahydropyridine (MPTP)-treated mice reduces locomotor activity induced by L-dopa
    • Nishi K, Kondo T, & Narabayashi H (1991) Destruction of norepinephrine terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice reduces locomotor activity induced by L-dopa. Neurosci Lett, 123, 244-247.
    • (1991) Neurosci. Lett. , vol.123 , pp. 244-247
    • Nishi, K.1    Kondo, T.2    Narabayashi, H.3
  • 43
    • 13844269035 scopus 로고    scopus 로고
    • Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice
    • Mori A, Ohashi S, Nakai M, Moriizumi T, & Mitsumoto Y (2005) Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice. Neurosci Res, 51, 265-274.
    • (2005) Neurosci. Res. , vol.51 , pp. 265-274
    • Mori, A.1    Ohashi, S.2    Nakai, M.3    Moriizumi, T.4    Mitsumoto, Y.5
  • 45
    • 0035960066 scopus 로고    scopus 로고
    • Mouse model of Parkinsonism: A comparison between subacute MPTP and chronic MPTP/probenecid treatment
    • Petroske E, Meredith GE, Callen S, Totterdell S, & Lau YS (2001) Mouse model of Parkinsonism: A comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience, 106, 589-601.
    • (2001) Neuroscience , vol.106 , pp. 589-601
    • Petroske, E.1    Meredith, G.E.2    Callen, S.3    Totterdell, S.4    Lau, Y.S.5
  • 46
    • 2342662120 scopus 로고    scopus 로고
    • Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone
    • Fleming SM, Zhu C, Fernagut PO, Mehta A, DiCarlo CD, Seaman RL, & Chesselet MF (2004) Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone. Exp Neurol, 187, 418-429.
    • (2004) Exp. Neurol. , vol.187 , pp. 418-429
    • Fleming, S.M.1    Zhu, C.2    Fernagut, P.O.3    Mehta, A.4    Dicarlo, C.D.5    Seaman, R.L.6    Chesselet, M.F.7
  • 47
    • 79953704795 scopus 로고    scopus 로고
    • Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: A cautionary note
    • Klein A, Gidyk DC, Shriner AM, Colwell KL, Tatton NA, Tatton WG, & Metz GA (2011) Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: A cautionary note. Behav Brain Res, 222, 33-42.
    • (2011) Behav. Brain Res. , vol.222 , pp. 33-42
    • Klein, A.1    Gidyk, D.C.2    Shriner, A.M.3    Colwell, K.L.4    Tatton, N.A.5    Tatton, W.G.6    Metz, G.A.7
  • 48
    • 0030933637 scopus 로고    scopus 로고
    • Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats
    • Menzaghi F, Whelan KT, Risbrough VB, Rao TS, & Lloyd GK (1997) Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats. J Pharmacol Exp Ther, 280, 393-401.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 393-401
    • Menzaghi, F.1    Whelan, K.T.2    Risbrough, V.B.3    Rao, T.S.4    Lloyd, G.K.5
  • 49
    • 0033967160 scopus 로고    scopus 로고
    • The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat
    • Dawson L, Chadha A, Megalou M, & Duty S (2000) The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat. Br J Pharmacol, 129, 541-546.
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 541-546
    • Dawson, L.1    Chadha, A.2    Megalou, M.3    Duty, S.4
  • 50
    • 0000428532 scopus 로고
    • 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists
    • Carlsson A, Lindqvist M, & Magnusson T (1957) 3,4- Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists. Nature, 180, 1200.
    • (1957) Nature , vol.180 , pp. 1200
    • Carlsson, A.1    Lindqvist, M.2    Magnusson, T.3
  • 52
    • 80052771247 scopus 로고    scopus 로고
    • Effects of ethanolic extract of pine needles (Pinus eldarica Medw.) on reserpine-induced depression-like behavior in maleWistar rats
    • Bolandghamat S, Moghimi A,&IranshahiM(2011) Effects of ethanolic extract of pine needles (Pinus eldarica Medw.) on reserpine-induced depression-like behavior in maleWistar rats. Pharmacogn Mag, 7, 248-253.
    • (2011) Pharmacogn. Mag. , vol.7 , pp. 248-253
    • Bolandghamat, S.1    Moghimi, A.2    Iranshahi, M.3
  • 53
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • Corti O, Lesage S, & Brice A (2011) What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol Rev, 91, 1161-1218.
    • (2011) Physiol. Rev. , vol.91 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 56
    • 37549030985 scopus 로고    scopus 로고
    • In vivo alpha-synuclein overexpression in rodents: A useful model of Parkinson's disease
    • Chesselet MF (2008) In vivo alpha-synuclein overexpression in rodents: A useful model of Parkinson's disease? Exp Neurol, 209, 22-27.
    • (2008) Exp. Neurol. , vol.209 , pp. 22-27
    • Chesselet, M.F.1
  • 57
    • 33745916124 scopus 로고    scopus 로고
    • Brain reward in the absence of alpha-synuclein
    • Oksman M, Tanila H, & Yavich L (2006) Brain reward in the absence of alpha-synuclein. Neuroreport, 17, 1191-1194.
    • (2006) Neuroreport , vol.17 , pp. 1191-1194
    • Oksman, M.1    Tanila, H.2    Yavich, L.3
  • 58
    • 0345269757 scopus 로고    scopus 로고
    • Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of Parkinson's disease
    • Kirik D, Annett LE, Burger C, Muzyczka N, Mandel RJ, & Bjorklund A (2003) Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of Parkinson's disease. Proc Natl Acad Sci U S A, 100, 2884-2889.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2884-2889
    • Kirik, D.1    Annett, L.E.2    Burger, C.3    Muzyczka, N.4    Mandel, R.J.5    Bjorklund, A.6
  • 63
    • 13844313915 scopus 로고    scopus 로고
    • Parkin-deficient mice are not a robust model of parkinsonism
    • Perez FA, & Palmiter RD (2005) Parkin-deficient mice are not a robust model of parkinsonism. Proc Natl Acad Sci U S A, 102, 2174-2179.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2174-2179
    • Perez, F.A.1    Palmiter, R.D.2
  • 65
    • 0034934620 scopus 로고    scopus 로고
    • Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: Potential mouse model for parkinsonism
    • Mooslehner KA, Chan PM, Xu W, Liu L, Smadja C, Humby T, Allen ND, Wilkinson LS, & Emson PC (2001) Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: Potential mouse model for parkinsonism. Mol Cell Biol, 21, 5321-5331.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 5321-5331
    • Mooslehner, K.A.1    Chan, P.M.2    Xu, W.3    Liu, L.4    Smadja, C.5    Humby, T.6    Allen, N.D.7    Wilkinson, L.S.8    Emson, P.C.9
  • 68
    • 0031458637 scopus 로고    scopus 로고
    • Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action
    • Fon EA, Pothos EN, Sun BC, Killeen N, Sulzer D, & Edwards RH (1997) Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron, 19, 1271-1283.
    • (1997) Neuron , vol.19 , pp. 1271-1283
    • Fon, E.A.1    Pothos, E.N.2    Sun, B.C.3    Killeen, N.4    Sulzer, D.5    Edwards, R.H.6
  • 70
    • 52449135495 scopus 로고    scopus 로고
    • Pathophysiology of parkinsonism
    • Galvan A, & Wichmann T (2008) Pathophysiology of parkinsonism. Clin Neurophysiol, 119, 1459-1474.
    • (2008) Clin. Neurophysiol. , vol.119 , pp. 1459-1474
    • Galvan, A.1    Wichmann, T.2
  • 71
    • 26044469856 scopus 로고    scopus 로고
    • A comparison of degeneration in motor thalamus and cortex between progressive supranuclear palsy and Parkinson's disease
    • Halliday GM, Macdonald V, & Henderson JM (2005) A comparison of degeneration in motor thalamus and cortex between progressive supranuclear palsy and Parkinson's disease. Brain, 128, 2272-2280.
    • (2005) Brain , vol.128 , pp. 2272-2280
    • Halliday, G.M.1    MacDonald, V.2    Henderson, J.M.3
  • 72
    • 0030976005 scopus 로고    scopus 로고
    • The neostriatum beyond the motor function: Experimental and clinical evidence
    • Calabresi P, De Murtas M, & Bernardi G (1997) The neostriatum beyond the motor function: Experimental and clinical evidence. Neuroscience, 78, 39-60.
    • (1997) Neuroscience , vol.78 , pp. 39-60
    • Calabresi, P.1    De Murtas, M.2    Bernardi, G.3
  • 73
    • 0034883022 scopus 로고    scopus 로고
    • Serotonindopamine interactions in the control of conditioned reinforcement and motor behavior
    • Sasaki-Adams DM, & Kelley AE (2001) Serotonindopamine interactions in the control of conditioned reinforcement and motor behavior. Neuropsychopharmacology, 25, 440-452.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 440-452
    • Sasaki-Adams, D.M.1    Kelley, A.E.2
  • 75
    • 0037309371 scopus 로고    scopus 로고
    • Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systems
    • Zhou FM,Wilson C,&Dani JA(2003) Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systems. Neuroscientist, 9, 23-36.
    • (2003) Neuroscientist , vol.9 , pp. 23-36
    • Zhou, F.M.1    Wilson, C.2    Dani, J.A.3
  • 76
    • 0001646522 scopus 로고
    • Biochemical pharmacology of midbrain dopaminergic neurons
    • (F. Bloom, D. Kupfer, eds.), LippincottWilliam & Wilkins, New York
    • Roth RH,&Elsworth JD (1995) Biochemical pharmacology of midbrain dopaminergic neurons. In The Forth Generation of progress (F. Bloom, D. Kupfer, eds.), LippincottWilliam & Wilkins, New York, pp. 227-243.
    • (1995) Forth Generation of Progress , pp. 227-243
    • Roth, R.H.1    Elsworth, J.D.2
  • 77
    • 34548547156 scopus 로고    scopus 로고
    • Triple uptake inhibitors: Therapeutic potential in depression and beyond
    • Chen Z,&Skolnick P (2007) Triple uptake inhibitors: Therapeutic potential in depression and beyond. Expert Opin Investig Drugs, 16, 1365-1377.
    • (2007) Expert Opin. Investig. Drugs , vol.16 , pp. 1365-1377
    • Chen, Z.1    Skolnick, P.2
  • 78
    • 33847767095 scopus 로고    scopus 로고
    • The role of dopamine in the pathophysiology of depression
    • Dunlop BW, & Nemeroff CB (2007) The role of dopamine in the pathophysiology of depression. Arch Gen Psychiatry, 64, 327-337.
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 327-337
    • Dunlop, B.W.1    Nemeroff, C.B.2
  • 79
    • 20444477480 scopus 로고    scopus 로고
    • Depression in Parkinson's disease: Loss of dopamine and noradrenaline innervation in the limbic system
    • Remy P, Doder M, Lees A, Turjanski N, & Brooks D (2005) Depression in Parkinson's disease: Loss of dopamine and noradrenaline innervation in the limbic system. Brain, 128, 1314-1322.
    • (2005) Brain , vol.128 , pp. 1314-1322
    • Remy, P.1    Doder, M.2    Lees, A.3    Turjanski, N.4    Brooks, D.5
  • 80
    • 0025061257 scopus 로고
    • Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: Evidence that dopamine is taken up in vivo by noradrenergic terminals
    • Carboni E, Tanda GL, Frau R, & Di Chiara G (1990) Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: Evidence that dopamine is taken up in vivo by noradrenergic terminals. J Neurochem, 55, 1067-1070.
    • (1990) J. Neurochem. , vol.55 , pp. 1067-1070
    • Carboni, E.1    Tanda, G.L.2    Frau, R.3    Di Chiara, G.4
  • 81
    • 0030867369 scopus 로고    scopus 로고
    • The mesolimbic dopamine system as a target for rapid antidepressant action
    • Willner P (1997) The mesolimbic dopamine system as a target for rapid antidepressant action. Int Clin Psychopharmacol, 12(Suppl 3), S7-S14.
    • (1997) Int. Clin. Psychopharmacol. , vol.12 , Issue.SUPPL. 3
    • Willner, P.1
  • 82
    • 0028060394 scopus 로고
    • Reversal of stress-induced anhedonia by the dopamine receptor agonist, pramipexole
    • Willner P, Lappas S, Cheeta S, & Muscat R (1994) Reversal of stress-induced anhedonia by the dopamine receptor agonist, pramipexole. Psychopharmacology (Berl), 115, 454-462.
    • (1994) Psychopharmacology (Berl. , vol.115 , pp. 454-462
    • Willner, P.1    Lappas, S.2    Cheeta, S.3    Muscat, R.4
  • 83
    • 76649108189 scopus 로고    scopus 로고
    • High-frequency stimulation of the subthalamic nucleus and L-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson's disease
    • Navailles S, Benazzouz A, Bioulac B, Gross C, & De Deurwaerdere P (2010) High-frequency stimulation of the subthalamic nucleus and L-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson's disease. J Neurosci, 30, 2356-2364.
    • (2010) J. Neurosci. , vol.30 , pp. 2356-2364
    • Navailles, S.1    Benazzouz, A.2    Bioulac, B.3    Gross, C.4    De Deurwaerdere, P.5
  • 84
    • 33645675839 scopus 로고    scopus 로고
    • Short review on dopamine agonists: Insight into clinical and research studies relevant to Parkinson's disease
    • Radad K, Gille G, & Rausch WD (2005) Short review on dopamine agonists: Insight into clinical and research studies relevant to Parkinson's disease. Pharmacol Rep, 57, 701-712.
    • (2005) Pharmacol. Rep. , vol.57 , pp. 701-712
    • Radad, K.1    Gille, G.2    Rausch, W.D.3
  • 85
    • 0029958441 scopus 로고    scopus 로고
    • High affinity binding for pramipexole, a dopamine D3 receptor ligand, in rat striatum
    • PierceyMF,Walker EL, Feldpausch DL,&Camacho-Ochoa M(1996) High affinity binding for pramipexole, a dopamine D3 receptor ligand, in rat striatum. Neurosci Lett, 219, 138-140.
    • (1996) Neurosci. Lett. , vol.219 , pp. 138-140
    • Piercey, M.F.1    Walker, F.L.2    Feldpausch, D.L.3    Camacho-Ochoa, M.4
  • 86
    • 0030828275 scopus 로고    scopus 로고
    • Antidepressant effects of pramipexole, a novel dopamine receptor agonist
    • Maj J, Rogoz Z, Skuza G,&KolodziejczykK(1997) Antidepressant effects of pramipexole, a novel dopamine receptor agonist. J Neural Transm, 104, 525-533.
    • (1997) J. Neural. Transm. , vol.104 , pp. 525-533
    • Maj, J.1    Rogoz, Z.2    Skuza, G.3    Kolodziejczyk, K.4
  • 87
    • 67651091567 scopus 로고    scopus 로고
    • Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats
    • Breuer ME, Groenink L, Oosting RS, Buerger E, Korte M, Ferger B, & Olivier B (2009) Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats. Eur J Pharmacol, 616, 134-140.
    • (2009) Eur. J. Pharmacol. , vol.616 , pp. 134-140
    • Breuer, M.E.1    Groenink, L.2    Oosting, R.S.3    Buerger, E.4    Korte, M.5    Ferger, B.6    Olivier, B.7
  • 90
    • 0026076047 scopus 로고
    • The neuropathologic basis of different clinical subgroups of Parkinson's disease
    • Paulus W, & Jellinger K (1991) The neuropathologic basis of different clinical subgroups of Parkinson's disease. J Neuropathol Exp Neurol, 50, 743-755.
    • (1991) J. Neuropathol. Exp. Neurol. , vol.50 , pp. 743-755
    • Paulus, W.1    Jellinger, K.2
  • 91
    • 0021357276 scopus 로고
    • Altered serotonin metabolism in depressed patients with parkinson's disease
    • Mayeux R, Stern Y, Cote L, & Williams JB (1984) Altered serotonin metabolism in depressed patients with parkinson's disease. Neurology, 34, 642-646.
    • (1984) Neurology , vol.34 , pp. 642-646
    • Mayeux, R.1    Stern, Y.2    Cote, L.3    Williams, J.B.4
  • 93
    • 77956482166 scopus 로고    scopus 로고
    • Will deep-brain stimulation be as successful in major depression as it has been in Parkinson's disease
    • Kuhn J, & HuffW(2010)Will deep-brain stimulation be as successful in major depression as it has been in Parkinson's disease? Expert Rev Neurother, 10, 1363-1365.
    • (2010) Expert Rev. Neurother. , vol.10 , pp. 1363-1365
    • Kuhn, J.1    Huff, W.2
  • 94
    • 0033749345 scopus 로고    scopus 로고
    • MPTP susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences
    • Sedelis M, Hofele K, Auburger GW, Morgan S, Huston JP, & Schwarting RK (2000) MPTP susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences. Behav Genet, 30, 171-182.
    • (2000) Behav. Genet. , vol.30 , pp. 171-182
    • Sedelis, M.1    Hofele, K.2    Auburger, G.W.3    Morgan, S.4    Huston, J.P.5    Schwarting, R.K.6
  • 96
    • 79959810595 scopus 로고    scopus 로고
    • Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats
    • Casas S, Garcia S, Cabrera R, Nanfaro F, Escudero C, & Yunes R (2011) Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats. Pharmacol Biochem Behav, 99, 614-618.
    • (2011) Pharmacol. Biochem. Behav. , vol.99 , pp. 614-618
    • Casas, S.1    Garcia, S.2    Cabrera, R.3    Nanfaro, F.4    Escudero, C.5    Yunes, R.6
  • 97
    • 38649101598 scopus 로고    scopus 로고
    • Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats
    • Borah A, & Mohanakumar KP (2007) Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats. Cell Mol Neurobiol, 27, 985-996.
    • (2007) Cell Mol. Neurobiol. , vol.27 , pp. 985-996
    • Borah, A.1    Mohanakumar, K.P.2
  • 99
    • 77549083048 scopus 로고    scopus 로고
    • Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson's disease
    • Navailles S, Bioulac B, Gross C, & De Deurwaerdere P (2010) Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson's disease. Neurobiol Dis, 38, 136-143.
    • (2010) Neurobiol. Dis. , vol.38 , pp. 136-143
    • Navailles, S.1    Bioulac, B.2    Gross, C.3    De Deurwaerdere, P.4
  • 100
    • 65049083026 scopus 로고    scopus 로고
    • 5-HT(1A) receptor function in major depressive disorder
    • Savitz J, Lucki I, & Drevets WC (2009) 5-HT(1A) receptor function in major depressive disorder. Prog Neurobiol, 88, 17-31.
    • (2009) Prog. Neurobiol. , vol.88 , pp. 17-31
    • Savitz, J.1    Lucki, I.2    Drevets, W.C.3
  • 102
    • 0342546475 scopus 로고    scopus 로고
    • Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study
    • Auer DP, Putz B, Kraft E, Lipinski B, Schill J, & Holsboer F (2000) Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry, 47, 305-313.
    • (2000) Biol. Psychiatry , vol.47 , pp. 305-313
    • Auer, D.P.1    Putz, B.2    Kraft, E.3    Lipinski, B.4    Schill, J.5    Holsboer, F.6
  • 103
    • 33846877408 scopus 로고    scopus 로고
    • Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy
    • Hasler G, van der Veen JW, Tumonis T, Meyers N, Shen J, & Drevets WC (2007) Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Arch Gen Psychiatry, 64, 193-200.
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 193-200
    • Hasler, G.1    Van Der Veen, J.W.2    Tumonis, T.3    Meyers, N.4    Shen, J.5    Drevets, W.C.6
  • 104
  • 105
    • 79960085288 scopus 로고    scopus 로고
    • Glutamatergic drive of the dorsal raphe nucleus
    • Soiza-Reilly M, & Commons KG (2011) Glutamatergic drive of the dorsal raphe nucleus. J Chem Neuroanat, 41, 247-255.
    • (2011) J. Chem. Neuroanat. , vol.41 , pp. 247-255
    • Soiza-Reilly, M.1    Commons, K.G.2
  • 106
    • 42949123365 scopus 로고    scopus 로고
    • Targeting the glutamatergic system to develop novel improved therapeutics for mood disorders
    • Sanacora G, Zarate CA, Krystal JH,&ManjiHK(2008) Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov, 7, 426-437.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 426-437
    • Sanacora, G.1    Zarate, C.A.2    Krystal, J.H.3    Manji, H.K.4
  • 108
    • 79959350106 scopus 로고    scopus 로고
    • Involvement ofAMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression
    • KoikeH, Iijima M,&Chaki S (2011) Involvement ofAMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression. Behav Brain Res, 224, 107-111.
    • (2011) Behav. Brain Res. , vol.224 , pp. 107-111
    • Koike, H.1    Iijima, M.2    Chaki, S.3
  • 110
    • 79953064841 scopus 로고    scopus 로고
    • The GABAergic deficit hypothesis of major depressive disorder
    • Luscher B, Shen Q, & Sahir N (2011) The GABAergic deficit hypothesis of major depressive disorder. Mol Psychiatry, 16, 383-406.
    • (2011) Mol. Psychiatry , vol.16 , pp. 383-406
    • Luscher, B.1    Shen, Q.2    Sahir, N.3
  • 111
    • 36048976944 scopus 로고    scopus 로고
    • Role of GABA in anxiety and depression
    • Kalueff AV,&Nutt DJ (2007) Role of GABA in anxiety and depression. Depress Anxiety, 24, 495-517.
    • (2007) Depress Anxiety , vol.24 , pp. 495-517
    • Kalueff, A.V.1    Nutt, D.J.2
  • 112
    • 34147178089 scopus 로고    scopus 로고
    • GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states
    • Earnheart JC, Schweizer C, Crestani F, Iwasato T, Itohara S, Mohler H, & Luscher B (2007) GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J Neurosci, 27, 3845-3854.
    • (2007) J. Neurosci. , vol.27 , pp. 3845-3854
    • Earnheart, J.C.1    Schweizer, C.2    Crestani, F.3    Iwasato, T.4    Itohara, S.5    Mohler, H.6    Luscher, B.7
  • 113
    • 77956118577 scopus 로고    scopus 로고
    • Gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression
    • Shen Q, Lal R, Luellen BA, Earnheart JC, Andrews AM, & Luscher B (2010) gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. Biol Psychiatry, 68, 512-520.
    • (2010) Biol. Psychiatry , vol.68 , pp. 512-520
    • Shen, Q.1    Lal, R.2    Luellen, B.A.3    Earnheart, J.C.4    Andrews, A.M.5    Luscher, B.6
  • 114
    • 47749083851 scopus 로고    scopus 로고
    • GABA(A)R plasticity during pregnancy: Relevance to postpartum depression
    • Maguire J, & Mody I (2008) GABA(A)R plasticity during pregnancy: Relevance to postpartum depression. Neuron, 59, 207-213.
    • (2008) Neuron , vol.59 , pp. 207-213
    • Maguire, J.1    Mody, I.2
  • 115
    • 79955629703 scopus 로고    scopus 로고
    • Cholinergic receptor subtypes and their role in cognition, emotion, and vigilance control: An overview of preclinical and clinical findings
    • Graef S, Schonknecht P, Sabri O,&HegerlU(2011) Cholinergic receptor subtypes and their role in cognition, emotion, and vigilance control: An overview of preclinical and clinical findings. Psychopharmacology (Berl), 215, 205-229.
    • (2011) Psychopharmacology (Berl. , vol.215 , pp. 205-229
    • Graef, S.1    Schonknecht, P.2    Sabri, O.3    Hegerl, U.4
  • 116
    • 33749333018 scopus 로고    scopus 로고
    • Antidepressant efficacy of the antimuscarinic drug scopolamine: A randomized, placebo-controlled clinical trial
    • Furey ML, & Drevets WC (2006) Antidepressant efficacy of the antimuscarinic drug scopolamine: A randomized, placebo-controlled clinical trial. Arch Gen Psychiatry, 63, 1121-1129.
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 1121-1129
    • Furey, M.L.1    Drevets, W.C.2
  • 117
    • 19844375159 scopus 로고    scopus 로고
    • The Flinders Sensitive Line rat: A selectively bred putative animal model of depression
    • Overstreet DH, Friedman E, Mathe AA, & Yadid G (2005) The Flinders Sensitive Line rat: A selectively bred putative animal model of depression. Neurosci Biobehav Rev, 29, 739-759.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 739-759
    • Overstreet, D.H.1    Friedman, E.2    Mathe, A.A.3    Yadid, G.4
  • 118
    • 75849117116 scopus 로고    scopus 로고
    • Replication of scopolamine's antidepressant efficacy in major depressive disorder: A randomized, placebo-controlled clinical trial
    • Drevets WC, & Furey ML (2010) Replication of scopolamine's antidepressant efficacy in major depressive disorder: A randomized, placebo-controlled clinical trial. Biol Psychiatry, 67, 432-438.
    • (2010) Biol. Psychiatry , vol.67 , pp. 432-438
    • Drevets, W.C.1    Furey, M.L.2
  • 119
    • 7444253542 scopus 로고    scopus 로고
    • High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation
    • Caldarone BJ, Harrist A, Cleary MA, Beech RD, King SL, &PicciottoMR(2004) High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biol Psychiatry, 56, 657-664.
    • (2004) Biol. Psychiatry , vol.56 , pp. 657-664
    • Caldarone, B.J.1    Harrist, A.2    Cleary, M.A.3    Beech, R.D.4    King, S.L.5    Picciotto, M.R.6
  • 120
    • 34047183628 scopus 로고    scopus 로고
    • Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice
    • Mineur YS, Somenzi O, & Picciotto MR (2007) Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice. Neuropharmacology, 52, 1256-1262.
    • (2007) Neuropharmacology , vol.52 , pp. 1256-1262
    • Mineur, Y.S.1    Somenzi, O.2    Picciotto, M.R.3
  • 121
    • 33751092270 scopus 로고    scopus 로고
    • The nicotinic antagonist mecamylamine has antidepressantlike effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice
    • Rabenstein RL, Caldarone BJ, & Picciotto MR (2006) The nicotinic antagonist mecamylamine has antidepressantlike effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacology (Berl), 189, 395-401.
    • (2006) Psychopharmacology (Berl. , vol.189 , pp. 395-401
    • Rabenstein, R.L.1    Caldarone, B.J.2    Picciotto, M.R.3
  • 122
    • 77954941459 scopus 로고    scopus 로고
    • Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior
    • Turner JR, Castellano LM, & Blendy JA (2010) Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior. J Pharmacol Exp Ther, 334, 665-672.
    • (2010) J. Pharmacol. Exp. Ther. , vol.334 , pp. 665-672
    • Turner, J.R.1    Castellano, L.M.2    Blendy, J.A.3
  • 126
    • 34547916390 scopus 로고    scopus 로고
    • Treatment options in the modern management of Parkinson disease
    • Schapira AH (2007) Treatment options in the modern management of Parkinson disease. Arch Neurol, 64, 1083-1088.
    • (2007) Arch. Neurol. , vol.64 , pp. 1083-1088
    • Schapira, A.H.1
  • 129
    • 0033971607 scopus 로고    scopus 로고
    • The role of receptor structure in determining adenosine receptor activity
    • Olah ME, & Stiles GL (2000) The role of receptor structure in determining adenosine receptor activity. Pharmacol Ther, 85, 55-75.
    • (2000) Pharmacol. Ther. , vol.85 , pp. 55-75
    • Olah, M.E.1    Stiles, G.L.2
  • 130
    • 0032781426 scopus 로고    scopus 로고
    • Distribution, biochemistry and function of striatal adenosine A2A receptors
    • Svenningsson P, Le Moine C, Fisone G, & Fredholm BB (1999) Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol, 59, 355-396.
    • (1999) Prog. Neurobiol. , vol.59 , pp. 355-396
    • Svenningsson, P.1    Le Moine, C.2    Fisone, G.3    Fredholm, B.B.4
  • 131
    • 0030615062 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonism potentiates LDOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats
    • Fenu S, Pinna A, Ongini E, & Morelli M (1997) Adenosine A2A receptor antagonism potentiates LDOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur J Pharmacol, 321, 143-147.
    • (1997) Eur. J. Pharmacol. , vol.321 , pp. 143-147
    • Fenu, S.1    Pinna, A.2    Ongini, E.3    Morelli, M.4
  • 132
    • 0035283648 scopus 로고    scopus 로고
    • Motor stimulant effects of the adenosine A2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopamine- lesioned rats
    • Pinna A, Fenu S, & Morelli M (2001) Motor stimulant effects of the adenosine A2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopamine-lesioned rats. Synapse, 39, 233-238.
    • (2001) Synapse , vol.39 , pp. 233-238
    • Pinna, A.1    Fenu, S.2    Morelli, M.3
  • 133
    • 34249034952 scopus 로고    scopus 로고
    • Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: Acute and subchronic studies in rats
    • Tronci E, Simola N, Borsini F, Schintu N, Frau L, Carminati P, &MorelliM(2007) Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: Acute and subchronic studies in rats. Eur J Pharmacol, 566, 94-102.
    • (2007) Eur. J. Pharmacol. , vol.566 , pp. 94-102
    • Tronci, E.1    Simola, N.2    Borsini, F.3    Schintu, N.4    Frau, L.5    Carminati, P.6    Morelli, M.7
  • 134
    • 0036020950 scopus 로고    scopus 로고
    • Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease
    • Ikeda K, Kurokawa M, Aoyama S, & Kuwana Y (2002) Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease. J Neurochem, 80, 262-270.
    • (2002) J. Neurochem. , vol.80 , pp. 262-270
    • Ikeda, K.1    Kurokawa, M.2    Aoyama, S.3    Kuwana, Y.4
  • 135
    • 70450219517 scopus 로고    scopus 로고
    • Inactivation of neuronal forebrain A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease
    • Carta AR, Kachroo A, Schintu N, Xu K, Schwarzschild MA, Wardas J, & Morelli M (2009) Inactivation of neuronal forebrain A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neurochem, 111, 1478-1489.
    • (2009) J. Neurochem. , vol.111 , pp. 1478-1489
    • Carta, A.R.1    Kachroo, A.2    Schintu, N.3    Xu, K.4    Schwarzschild, M.A.5    Wardas, J.6    Morelli, M.7
  • 136
    • 0028205230 scopus 로고
    • Stress and adenosine: I Effect of methylxanthine and amphetamine stimulants on learned helplessness in rats
    • Minor TR, Chang WC, & Winslow JL (1994) Stress and adenosine: I. Effect of methylxanthine and amphetamine stimulants on learned helplessness in rats. Behav Neurosci, 108, 254-264.
    • (1994) Behav. Neurosci. , Issue.108 , pp. 254-264
    • Minor, T.R.1    Chang, W.C.2    Winslow, J.L.3
  • 137
    • 0031978904 scopus 로고    scopus 로고
    • Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats
    • Woodson JC, Minor TR, & Job RF (1998) Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats. Behav Neurosci, 112, 399-409.
    • (1998) Behav. Neurosci. , vol.112 , pp. 399-409
    • Woodson, J.C.1    Minor, T.R.2    Job, R.F.3
  • 138
    • 0021861536 scopus 로고
    • Purine nucleoside-mediated immobility in mice: Reversal by antidepressants
    • Kulkarni SK, & Mehta AK (1985) Purine nucleoside-mediated immobility in mice: Reversal by antidepressants. Psychopharmacology (Berl), 85, 460-463.
    • (1985) Psychopharmacology (Berl. , vol.85 , pp. 460-463
    • Kulkarni, S.K.1    Mehta, A.K.2
  • 139
    • 0034741713 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists are potential antidepressants: Evidence based on pharmacology and A2A receptor knockout mice
    • ElYacoubi M, Ledent C, Parmentier M, Bertorelli R, Ongini E, Costentin J, & Vaugeois JM (2001) Adenosine A2A receptor antagonists are potential antidepressants: Evidence based on pharmacology and A2A receptor knockout mice. Br J Pharmacol, 134, 68-77.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 68-77
    • Elyacoubi, M.1    Ledent, C.2    Parmentier, M.3    Bertorelli, R.4    Ongini, E.5    Costentin, J.6    Vaugeois, J.M.7
  • 141
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, & Nestler EJ (2008) The molecular neurobiology of depression. Nature, 455, 894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 142
    • 40849133755 scopus 로고    scopus 로고
    • Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators
    • McEwen BS (2008) Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol, 583, 174-185.
    • (2008) Eur. J. Pharmacol. , vol.583 , pp. 174-185
    • McEwen, B.S.1
  • 143
    • 0032899957 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor in depression and anxiety disorders
    • Arborelius L, Owens MJ, Plotsky PM, & Nemeroff CB (1999) The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol, 160, 1-12.
    • (1999) J. Endocrinol. , vol.160 , pp. 1-12
    • Arborelius, L.1    Owens, M.J.2    Plotsky, P.M.3    Nemeroff, C.B.4
  • 144
    • 0035153486 scopus 로고    scopus 로고
    • Stress, hypercortisolism and corticosteroid receptors in depression: Implications for therapy
    • Holsboer F (2001) Stress, hypercortisolism and corticosteroid receptors in depression: Implications for therapy. J Affect Disord, 62, 77-91.
    • (2001) J. Affect. Disord. , vol.62 , pp. 77-91
    • Holsboer, F.1
  • 145
    • 17444411960 scopus 로고    scopus 로고
    • Depression in women
    • Noble RE (2005) Depression in women. Metabolism, 54, 49-52.
    • (2005) Metabolism , vol.54 , pp. 49-52
    • Noble, R.E.1
  • 146
    • 33745743469 scopus 로고    scopus 로고
    • Factors producing a menopausal depressive-like state in mice following ovariectomy
    • Bekku N, Yoshimura H, & Araki H (2006) Factors producing a menopausal depressive-like state in mice following ovariectomy. Psychopharmacology (Berl), 187, 170-180.
    • (2006) Psychopharmacology (Berl. , vol.187 , pp. 170-180
    • Bekku, N.1    Yoshimura, H.2    Araki, H.3
  • 147
    • 34547838202 scopus 로고    scopus 로고
    • Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
    • Beckley EH, & Finn DA (2007) Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility. Pharmacol Biochem Behav, 87, 412-419.
    • (2007) Pharmacol. Biochem. Behav. , vol.87 , pp. 412-419
    • Beckley, E.H.1    Finn, D.A.2
  • 149
    • 0034891123 scopus 로고    scopus 로고
    • The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test
    • Urani A, Roman FJ, Phan VL, Su TP, & Maurice T (2001) The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test. J Pharmacol Exp Ther, 298, 1269-1279.
    • (2001) J. Pharmacol. Exp. Ther. , Issue.298 , pp. 1269-1279
    • Urani, A.1    Roman, F.J.2    Phan, V.L.3    Su, T.P.4    Maurice, T.5
  • 152
    • 0029970863 scopus 로고    scopus 로고
    • Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography
    • Uzunov DP, Cooper TB, Costa E, & Guidotti A (1996) Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. Proc Natl Acad Sci U S A, 93, 12599-12604.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12599-12604
    • Uzunov, D.P.1    Cooper, T.B.2    Costa, E.3    Guidotti, A.4
  • 153
    • 0033672097 scopus 로고    scopus 로고
    • Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha- pregnan-20-one in mice forced swim test
    • KhistiRT, ChopdeCT,&Jain SP (2000) Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test. Pharmacol Biochem Behav, 67, 137-143.
    • (2000) Pharmacol. Biochem. Behav. , vol.67 , pp. 137-143
    • Khisti, R.T.1    Chopde, C.T.2    Jain, S.P.3
  • 154
    • 0031004888 scopus 로고    scopus 로고
    • Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: Evidence for anterograde axonal transport
    • Conner JM, Lauterborn JC, Yan Q, Gall CM, & Varon S (1997) Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: Evidence for anterograde axonal transport. J Neurosci, 17, 2295-2313.
    • (1997) J. Neurosci. , vol.17 , pp. 2295-2313
    • Conner, J.M.1    Lauterborn, J.C.2    Yan, Q.3    Gall, C.M.4    Varon, S.5
  • 155
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang EJ, & Reichardt LF (2001) Neurotrophins: Roles in neuronal development and function. Annu Rev Neurosci, 24, 677-736.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 157
    • 0033597983 scopus 로고    scopus 로고
    • Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
    • Mogi M, Togari A, Kondo T, Mizuno Y, Komure O, Kuno S, Ichinose H, & Nagatsu T (1999) Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett, 270, 45-48.
    • (1999) Neurosci. Lett. , vol.270 , pp. 45-48
    • Mogi, M.1    Togari, A.2    Kondo, T.3    Mizuno, Y.4    Komure, O.5    Kuno, S.6    Ichinose, H.7    Nagatsu, T.8
  • 160
    • 13444273332 scopus 로고    scopus 로고
    • Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons
    • Porritt MJ, Batchelor PE, & Howells DW (2005) Inhibiting BDNF expression by antisense oligonucleotide infusion causes loss of nigral dopaminergic neurons. Exp Neurol, 192, 226-234.
    • (2005) Exp. Neurol. , vol.192 , pp. 226-234
    • Porritt, M.J.1    Batchelor, P.E.2    Howells, D.W.3
  • 161
    • 21544446985 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta
    • Baquet ZC, Bickford PC, & Jones KR (2005) Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta. J Neurosci, 25, 6251-6259.
    • (2005) J. Neurosci. , vol.25 , pp. 6251-6259
    • Baquet, Z.C.1    Bickford, P.C.2    Jones, K.R.3
  • 162
    • 0242637444 scopus 로고    scopus 로고
    • BDNF gene expression is reduced in the frontal cortex of dopamine transporter knockout mice
    • Fumagalli F, Racagni G, Colombo E, & Riva MA (2003) BDNF gene expression is reduced in the frontal cortex of dopamine transporter knockout mice. Mol Psychiatry, 8, 898-899.
    • (2003) Mol. Psychiatry , vol.8 , pp. 898-899
    • Fumagalli, F.1    Racagni, G.2    Colombo, E.3    Riva, M.A.4
  • 163
    • 79851511400 scopus 로고    scopus 로고
    • Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
    • Baydyuk M, Nguyen MT, & Xu B (2011) Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration. Exp Neurol, 228, 118-125.
    • (2011) Exp. Neurol. , vol.228 , pp. 118-125
    • Baydyuk, M.1    Nguyen, M.T.2    Xu, B.3
  • 164
    • 0035239020 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease
    • Murer MG, Yan Q, & Raisman-Vozari R (2001) Brainderived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Prog Neurobiol, 63, 71-124.
    • (2001) Prog. Neurobiol. , vol.63 , pp. 71-124
    • Murer, M.G.1    Yan, Q.2    Raisman-Vozari, R.3
  • 165
    • 0029610630 scopus 로고
    • Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
    • Levivier M, Przedborski S, Bencsics C, & Kang UJ (1995) Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J Neurosci, 15, 7810-7820.
    • (1995) J. Neurosci. , vol.15 , pp. 7810-7820
    • Levivier, M.1    Przedborski, S.2    Bencsics, C.3    Kang, U.J.4
  • 166
    • 0028868574 scopus 로고
    • Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres
    • Isacson O, Deacon TW, Pakzaban P, Galpern WR, Dinsmore J,&Burns LH (1995) Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres. Nat Med, 1, 1189-1194.
    • (1995) Nat. Med. , vol.1 , pp. 1189-1194
    • Isacson, O.1    Deacon, T.W.2    Pakzaban, P.3    Galpern, W.R.4    Dinsmore, J.5    Burns, L.H.6
  • 167
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brainderived neurotrophic factor and receptor tyrosine kinaseBin postmortem brain of suicide subjects
    • Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, & Pandey GN (2003) Altered gene expression of brainderived neurotrophic factor and receptor tyrosine kinaseBin postmortem brain of suicide subjects. Arch Gen Psychiatry, 60, 804-815.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 168
    • 55549139122 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: Implications for the role of neuroplasticity in depression
    • Brunoni AR, Lopes M, & Fregni F (2008) A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: Implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol, 11, 1169-1180.
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , pp. 1169-1180
    • Brunoni, A.R.1    Lopes, M.2    Fregni, F.3
  • 170
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • ShirayamaY, ChenAC, Nakagawa S, Russell DS,&Duman RS (2002) Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci, 22, 3251-3261.
    • (2002) J. Neurosci. , vol.22 , pp. 3251-3261
    • Shirayamay, A.1    Chen, C.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 171
    • 34248388548 scopus 로고    scopus 로고
    • VEGFis an essential mediator of the neurogenic and behavioral actions of antidepressants
    • Warner-Schmidt JL,&Duman RS (2007)VEGFis an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A, 104, 4647-4652.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4647-4652
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 172
    • 70349122023 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: Pharmacological and cellular characterization
    • Greene J, Banasr M, Lee B, Warner-Schmidt J, & Duman RS (2009) Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: Pharmacological and cellular characterization. Neuropsychopharmacology, 34, 2459-2468.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2459-2468
    • Greene, J.1    Banasr, M.2    Lee, B.3    Warner-Schmidt, J.4    Duman, R.S.5
  • 173
    • 34250624892 scopus 로고    scopus 로고
    • Favorable effects of VEGF gene transfer on a rat model of Parkinson disease using adenoassociated viral vectors
    • Tian YY, Tang CJ, Wang JN, Feng Y, Chen XW, Wang L, Qiao X, & Sun SG (2007) Favorable effects of VEGF gene transfer on a rat model of Parkinson disease using adenoassociated viral vectors. Neurosci Lett, 421, 239-244.
    • (2007) Neurosci. Lett. , vol.421 , pp. 239-244
    • Tian, Y.Y.1    Tang, C.J.2    Wang, J.N.3    Feng, Y.4    Chen, X.W.5    Wang, L.6    Qiao, X.7    Sun, S.G.8
  • 176
    • 0036455153 scopus 로고    scopus 로고
    • Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task
    • Kempermann G,&GageFH(2002) Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci, 16, 129-136.
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 129-136
    • Kempermann, G.1    Gagef, H.2
  • 179
    • 48249085840 scopus 로고    scopus 로고
    • Antidepressant drug-induced stimulation of mouse hippocampal neurogenesis is age-dependent and altered by early life stress
    • Navailles S, Hof PR, & Schmauss C (2008) Antidepressant drug-induced stimulation of mouse hippocampal neurogenesis is age-dependent and altered by early life stress. J Comp Neurol, 509, 372-381.
    • (2008) J. Comp. Neurol. , vol.509 , pp. 372-381
    • Navailles, S.1    Hof, P.R.2    Schmauss, C.3
  • 180
    • 33645646860 scopus 로고    scopus 로고
    • Dopaminergic substantia nigra neurons project topographically organized to the subventricular zone and stimulate precursor cell proliferation in aged primates
    • Freundlieb N, Francois C, Tande D, Oertel WH, Hirsch EC, & Hoglinger GU (2006) Dopaminergic substantia nigra neurons project topographically organized to the subventricular zone and stimulate precursor cell proliferation in aged primates. J Neurosci, 26, 2321-2325.
    • (2006) J. Neurosci. , vol.26 , pp. 2321-2325
    • Freundlieb, N.1    Francois, C.2    Tande, D.3    Oertel, W.H.4    Hirsch, E.C.5    Hoglinger, G.U.6
  • 183
    • 42949133399 scopus 로고    scopus 로고
    • Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice
    • Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, & Masliah E (2008) Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. J Neurosci, 28, 4250-4260.
    • (2008) J. Neurosci. , vol.28 , pp. 4250-4260
    • Crews, L.1    Mizuno, H.2    Desplats, P.3    Rockenstein, E.4    Adame, A.5    Patrick, C.6    Winner, B.7    Winkler, J.8    Masliah, E.9
  • 190
    • 0037110467 scopus 로고    scopus 로고
    • 5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus
    • Radley JJ, & Jacobs BL (2002) 5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus. Brain Res, 955, 264-267.
    • (2002) Brain Res. , vol.955 , pp. 264-267
    • Radley, J.J.1    Jacobs, B.L.2
  • 191
    • 1642331289 scopus 로고    scopus 로고
    • Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone
    • Banasr M, Hery M, Printemps R, & Daszuta A (2004) Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology, 29, 450-460.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 450-460
    • Banasr, M.1    Hery, M.2    Printemps, R.3    Daszuta, A.4
  • 192
    • 0036470165 scopus 로고    scopus 로고
    • Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons
    • Gao HM, Hong JS, Zhang W, & Liu B (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci, 22, 782-790.
    • (2002) J. Neurosci. , vol.22 , pp. 782-790
    • Gao, H.M.1    Hong, J.S.2    Zhang, W.3    Liu, B.4
  • 193
    • 0036459335 scopus 로고    scopus 로고
    • Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging
    • Cicchetti F, Brownell AL, Williams K, Chen YI, Livni E, & Isacson O (2002) Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. Eur J Neurosci, 15, 991-998.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 991-998
    • Cicchetti, F.1    Brownell, A.L.2    Williams, K.3    Chen, Y.I.4    Livni, E.5    Isacson, O.6
  • 194
    • 0036316772 scopus 로고    scopus 로고
    • Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease
    • Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, & Liu B (2002) Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease. J Neurochem, 81, 1285-1297.
    • (2002) J. Neurochem. , vol.81 , pp. 1285-1297
    • Gao, H.M.1    Jiang, J.2    Wilson, B.3    Zhang, W.4    Hong, J.S.5    Liu, B.6
  • 195
    • 0031881687 scopus 로고    scopus 로고
    • Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system
    • Castano A, Herrera AJ, Cano J, & Machado A (1998) Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system. J Neurochem, 70, 1584-1592.
    • (1998) J. Neurochem. , vol.70 , pp. 1584-1592
    • Castano, A.1    Herrera, A.J.2    Cano, J.3    MacHado, A.4
  • 196
    • 0033835748 scopus 로고    scopus 로고
    • The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system
    • Herrera AJ, Castano A, Venero JL, Cano J, & Machado A (2000) The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system. Neurobiol Dis, 7, 429-447.
    • (2000) Neurobiol. Dis. , vol.7 , pp. 429-447
    • Herrera, A.J.1    Castano, A.2    Venero, J.L.3    Cano, J.4    MacHado, A.5
  • 197
  • 198
    • 33645123006 scopus 로고    scopus 로고
    • Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: Role of tumor necrosis factoralpha
    • Sriram K, Miller DB,&O'Callaghan JP (2006) Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: Role of tumor necrosis factoralpha. J Neurochem, 96, 706-718.
    • (2006) J. Neurochem. , vol.96 , pp. 706-718
    • Sriram, K.1    Miller, D.B.2    O'Callaghan, J.P.3
  • 199
    • 0037031609 scopus 로고    scopus 로고
    • Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1 2 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra
    • Feng ZH, Wang TG, Li DD, Fung P, Wilson BC, Liu B, Ali SF, Langenbach R, & Hong JS (2002) Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. Neurosci Lett, 329, 354-358.
    • (2002) Neurosci. Lett. , vol.329 , pp. 354-358
    • Feng, Z.H.1    Wang, T.G.2    Li, D.D.3    Fung, P.4    Wilson, B.C.5    Liu, B.6    Ali, S.F.7    Langenbach, R.8    Hong, J.S.9
  • 200
    • 0037459783 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats
    • Sairam K, Saravanan KS, Banerjee R, & Mohanakumar KP (2003) Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. Brain Res, 966, 245-252.
    • (2003) Brain Res. , vol.966 , pp. 245-252
    • Sairam, K.1    Saravanan, K.S.2    Banerjee, R.3    Mohanakumar, K.P.4
  • 201
    • 0035134830 scopus 로고    scopus 로고
    • Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease
    • Teismann P, & Ferger B (2001) Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease. Synapse, 39, 167-174.
    • (2001) Synapse , vol.39 , pp. 167-174
    • Teismann, P.1    Ferger, B.2
  • 203
    • 0035800589 scopus 로고    scopus 로고
    • Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
    • He Y, Appel S, & Le W (2001) Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res, 909, 187-193.
    • (2001) Brain Res. , vol.909 , pp. 187-193
    • He, Y.1    Appel, S.2    Le, W.3
  • 204
  • 205
    • 2342538502 scopus 로고    scopus 로고
    • Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system
    • Tomas-Camardiel M, Rite I, Herrera AJ, de Pablos RM, Cano J, Machado A, & Venero JL (2004) Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system. Neurobiol Dis, 16, 190-201.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 190-201
    • Tomas-Camardiel, M.1    Rite, I.2    Herrera, A.J.3    De Pablos, R.M.4    Cano, J.5    MacHado, A.6    Venero, J.L.7
  • 206
    • 0027722985 scopus 로고
    • A review on the acute phase response in major depression
    • Maes M (1993) A review on the acute phase response in major depression. Rev Neurosci, 4, 407-416.
    • (1993) Rev. Neurosci. , vol.4 , pp. 407-416
    • Maes, M.1
  • 207
    • 48049084135 scopus 로고    scopus 로고
    • The cytokine hypothesis of depression: Inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
    • Maes M (2008) The cytokine hypothesis of depression: Inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro Endocrinol Lett, 29, 287-291.
    • (2008) Neuro. Endocrinol. Lett. , vol.29 , pp. 287-291
    • Maes, M.1
  • 208
    • 0028950478 scopus 로고
    • The monocyte-T-lymphocyte hypothesis of major depression
    • Maes M, Smith R, & Scharpe S (1995) The monocyte-T-lymphocyte hypothesis of major depression. Psychoneuroendocrinology, 20, 111-116.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 111-116
    • Maes, M.1    Smith, R.2    Scharpe, S.3
  • 209
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurodegenerative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression
    • Maes M, Yirmyia R, Noraberg J, Brene S, Hibbeln J, Perini G, Kubera M, Bob P, Lerer B, & Maj M (2009) The inflammatory & neurodegenerative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression. Metab Brain Dis, 24, 27-53.
    • (2009) Metab. Brain Dis. , vol.24 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3    Brene, S.4    Hibbeln, J.5    Perini, G.6    Kubera, M.7    Bob, P.8    Lerer, B.9    Maj, M.10
  • 210
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
    • Miller AH, Maletic V, & Raison CL (2009) Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression. Biol Psychiatry, 65, 732-741.
    • (2009) Biol. Psychiatry , vol.65 , pp. 732-741
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 211
    • 19944383201 scopus 로고    scopus 로고
    • Endotoxin- or pro-inflammatory cytokine-induced sickness behavior as an animal model of depression: Focus on anhedonia
    • De La Garza R, 2nd (2005) Endotoxin- or pro-inflammatory cytokine-induced sickness behavior as an animal model of depression: Focus on anhedonia. Neurosci Biobehav Rev, 29, 761-770.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 761-770
    • De La Garza, I.I.R.1
  • 212
    • 22044442141 scopus 로고    scopus 로고
    • Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice
    • Dunn AJ, & Swiergiel AH (2005) Effects of interleukin-1 and endotoxin in the forced swim and tail suspension tests in mice. Pharmacol Biochem Behav, 81, 688-693.
    • (2005) Pharmacol. Biochem. Behav. , vol.81 , pp. 688-693
    • Dunn, A.J.1    Swiergiel, A.H.2
  • 213
    • 45549084470 scopus 로고    scopus 로고
    • Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression
    • Goshen I, Kreisel T, Ben-Menachem-Zidon O, Licht T, Weidenfeld J, Ben-Hur T, & Yirmiya R (2008) Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Mol Psychiatry, 13, 717-728.
    • (2008) Mol. Psychiatry , vol.13 , pp. 717-728
    • Goshen, I.1    Kreisel, T.2    Ben-Menachem-Zidon, O.3    Licht, T.4    Weidenfeld, J.5    Ben-Hur, T.6    Yirmiya, R.7
  • 215
    • 78149466027 scopus 로고    scopus 로고
    • Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters
    • Zhu CB, Lindler KM, OwensAW,Daws LC, Blakely RD,& HewlettWA(2010) Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters. Neuropsychopharmacology, 35, 2510-2520.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2510-2520
    • Zhu, C.B.1    Lindler, K.M.2    Owensawdaws, L.C.3    Blakely, R.D.4    Hewlett, W.A.5
  • 216
    • 0037346906 scopus 로고    scopus 로고
    • Tolerance to the anhedonic effects of lipopolysaccharide is associated with changes in syntaxin immunoreactivity in the nucleus accumbens
    • Barr AM, Song C, Sawada K, Young CE, Honer WG, & Phillips AG (2003) Tolerance to the anhedonic effects of lipopolysaccharide is associated with changes in syntaxin immunoreactivity in the nucleus accumbens. Int J Neuropsychopharmacol, 6, 23-34.
    • (2003) Int. J. Neuropsychopharmacol. , vol.6 , pp. 23-34
    • Barr, A.M.1    Song, C.2    Sawada, K.3    Young, C.E.4    Honer, W.G.5    Phillips, A.G.6
  • 217
    • 0033601967 scopus 로고    scopus 로고
    • Stressor-induced alterations in serotonergic activity in an animal model of depression
    • Connor TJ, Song C, Leonard BE, Anisman H, & Merali Z (1999) Stressor-induced alterations in serotonergic activity in an animal model of depression. Neuroreport, 10, 523-528.
    • (1999) Neuroreport , vol.10 , pp. 523-528
    • Connor, T.J.1    Song, C.2    Leonard, B.E.3    Anisman, H.4    Merali, Z.5
  • 219
    • 0035118649 scopus 로고    scopus 로고
    • Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1beta in the rat
    • Castanon N, Bluthe RM, & Dantzer R (2001) Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1beta in the rat. Psychopharmacology (Berl), 154, 50-60.
    • (2001) Psychopharmacology (Berl. , vol.154 , pp. 50-60
    • Castanon, N.1    Bluthe, R.M.2    Dantzer, R.3
  • 220
    • 79954613032 scopus 로고    scopus 로고
    • Cytokines mediated inflammation and decreased neurogenesis in animal models of depression
    • Song C, & Wang H (2011) Cytokines mediated inflammation and decreased neurogenesis in animal models of depression. Prog Neuropsychopharmacol Biol Psychiatry, 35, 760-768.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 760-768
    • Song, C.1    Wang, H.2
  • 221
    • 0037079993 scopus 로고    scopus 로고
    • Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6
    • Vallieres L, Campbell IL, Gage FH,&Sawchenko PE(2002) Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. J Neurosci, 22, 486-492.
    • (2002) J. Neurosci. , vol.22 , pp. 486-492
    • Vallieres, L.1    Campbell, I.L.2    Gage, F.H.3    Sawchenko, P.E.4
  • 222
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje ML, Toda H, & Palmer TD (2003) Inflammatory blockade restores adult hippocampal neurogenesis. Science, 302, 1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 223
    • 33644960523 scopus 로고    scopus 로고
    • Neurogenic niche modulation by activated microglia: Transforming growth factor beta increases neurogenesis in the adult dentate gyrus
    • Battista D, Ferrari CC, Gage FH, & Pitossi FJ (2006) Neurogenic niche modulation by activated microglia: Transforming growth factor beta increases neurogenesis in the adult dentate gyrus. Eur J Neurosci, 23, 83-93.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 83-93
    • Battista, D.1    Ferrari, C.C.2    Gage, F.H.3    Pitossi, F.J.4
  • 226
    • 79956037017 scopus 로고    scopus 로고
    • Serotonindependent depression in Parkinson's disease: A role for the subthalamic nucleus
    • Tan SK, Hartung H, Sharp T, & Temel Y (2011) Serotonindependent depression in Parkinson's disease: A role for the subthalamic nucleus? Neuropharmacology, 61, 387-399.
    • (2011) Neuropharmacology , vol.61 , pp. 387-399
    • Tan, S.K.1    Hartung, H.2    Sharp, T.3    Temel, Y.4
  • 229
    • 3242795769 scopus 로고    scopus 로고
    • Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1 2 3,6-tetrahydropyridine-lesioned mouse basal ganglia
    • Fisher BE, Petzinger GM, Nixon K, Hogg E, Bremmer S, Meshul CK, & Jakowec MW (2004) Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia. J Neurosci Res, 77, 378-390.
    • (2004) J. Neurosci. Res. , vol.77 , pp. 378-390
    • Fisher, B.E.1    Petzinger, G.M.2    Nixon, K.3    Hogg, E.4    Bremmer, S.5    Meshul, C.K.6    Jakowec, M.W.7
  • 231
    • 0012849885 scopus 로고    scopus 로고
    • Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
    • Tillerson JL, Caudle WM, Reveron ME, & Miller GW (2003) Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease. Neuroscience, 119, 899-911.
    • (2003) Neuroscience , vol.119 , pp. 899-911
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 232
    • 40049093899 scopus 로고    scopus 로고
    • Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice
    • Duman CH, Schlesinger L, Russell DS,&Duman RS (2008) Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res, 1199, 148-158.
    • (2008) Brain Res. , vol.1199 , pp. 148-158
    • Duman, C.H.1    Schlesinger, L.2    Russell, D.S.3    Duman, R.S.4
  • 233


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.