Antidepressant-like effect of brain-derived neurotrophic factor (BDNF)

Pharmacology Biochemistry and Behavior

Volumn 56, Issue 1, 1996, Pages 131-137

  Siuciak, Judith A ^a   Lewis, Dacie R ^a   Wiegand, Stanley J ^a   Lindsay, Ronald M ^a  

^a REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

depression; dorsal raphe; forced swim test; learned helplessness; periaqueductal gray; rat; serotonin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG ACTIVITY; INTRACEREBRAL DRUG ADMINISTRATION; LEARNED HELPLESSNESS; LOCOMOTION; MALE; MONOAMINE METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION; SWIMMING;

ANIMALS; ANTIDEPRESSIVE AGENTS; AVOIDANCE LEARNING; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSION; ELECTROSHOCK; HELPLESSNESS, LEARNED; MALE; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; SWIMMING;

EID: 0031031001     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00169-4     Document Type: Article

References (66)

1. Altar C. A., Boylan C. B., Jackson C., Hershenson S., Miller J., Wiegand S. J., Lindsay R. M., Hyman C. Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo. Proc. Natl. Acad. Sci. USA. 89:1992;11347-11351.
2. Ballenger J. C., Post R. M., Jimerson D. C., Lake C. R., Zuckerman M. Neurobiological correlates of depression and anxiety in normal individuals. Post R. M., Ballenger J. C. Neurobiology of mood disorders. 1984;481-501 Williams and Wilkin, Baltimore.
3. Barchas J. D., Hamblin M. W., Malenka R. C. Biochemical hypotheses of mood and anxiety disorders. Siegel G. J., Agranoff B. W., Albers R. W., Molinoff P. B. Basic neurochemistry. 1994;979-1001 Raven Press, New York.
4. Boyer W. F., Feighner J. P. The serotonin hypothesis. Necessary but not sufficient Feighner J. P., Boyer W. F. Selective serotonin reuptake inhibitors. 1991;71-81 Wiley, New York.
5. Brown A. S., Gershon S. Dopamine and depression. J. Neural Trans. 91:1993;75-109.
6. Bunney W. E., Davis J. M. Norepinephrine in depressive reactions. Arch. Gen. Psychiatry. 13:1965;483-494.
7. Croll S. D., Wiegand S. J., Anderson K. D., Lindsay R. M., Nawa H. Neuropeptide regulation by BDNF and NGF in adult rat forebrain. Eur. J. Neurosci. 6:1994;1343-1353.
8. Del Zompo M., Bocchetta A., Bernardi F., Burrai C., Corsini G. U. Gessa G. L., Serra G. Dopamine and mental depression. 1990;177-184 Pergamon Press, New York.
9. Devoize J. L., Rigal F., Eschalier A., Trolese J. F., Renoux M. Influence of naloxone on antidepressant drug effects in the forced swimming test. Psychopharmacol. 84:1984;71-75.
10. Emrich H. M. Endorphins in psychiatry. Psychiat. Dev. 2:1984;97-114.
11. Green A. R., Peralta E., Hong J. S., Mao C. C., Aterwill C. K., Costa E. Alteration in GABA metabolism and met-enkephalin content in rat brain following repeated electroconvulsive shock therapy. J. Neurochem. 31:1978;607-611.
12. Hellhammer D. H., Rea M. A., Bell M., Belkein L., Ludwig M. Learned helplessness. Effects on brain monoamines and the pituitary gonadal axis Pharmacol. Biochem. Behav. 21:1984;481-485.
13. Hughes C. W., Kent T. A., Campbell J., Oke A., Croskell H., Preskorn S. H. Cerebral blood lfow and cerebrovascular permeability in an inescapable shock (learned helplessness) animal model of depression, Pharmacol. Biochem. Behav. 21:1984;891-894.
14. Jacobs B. L., Azmitia E. C. Structure and function of the brain serotonergic system. Physiol. Rev. 72:1992;165-229.
15. Kitada Y., Miyauchi T., Satoh A., Satoh S. Effects of antidepressants in the rat forced swimming test. Eur. J. Pharmacol. 72:1981;145-152.
16. Lapchak P. A., Hefti F. BDNF and NGF treat2ment in lesioned rats. Effects on cholinergic function and weight gain NeuroReport. 3:1992;405-408.
17. Lapchak P. A., Beck K. D., Araujo D. M., Irwin I., Langston J. W., Hefti F. Chronic intranigral administation of BDNF produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attentuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neurosci. 53:1993;639-650.
18. Leshner A. I., Remler H., Biegon A., Samuel D. Desmethylimipramine (DMI) counteracts learned helplessness in rats. Psychopharmacol. 66:1979;207-208.
19. Lindsay R. M. Brain-derived neurotrophic factor. An NGF- related neurotrophin Loughlin S. E., Fallon J. H. Neurotrophic factors. 1991;257-283 Academic Press, London.
20. Maier S. F., Grahn R. E., Kalman B. A., Sutton L. C., Wiertelak E. P., Watkins L. R. The role of the amygdala and dorsal raphe nucleus in mediating the behavioral consequences of inescapable shock. Behav. Neurosci. 107:1993;377-388.
21. Martin-Iverson M. T., Todd K. G., Altar C. A. Behavioral and in vivo neurochemical effects of the neurotrophic factors BDNF and NT-3 and their interaction with amphetamine. J. Neurosci. 14:1994;1262-1270.
22. Martin P., Soubrie P., Simon P. Noradrenergic and opioid mediation of tricyclic-induced reversal of escape deficits caused by inescapable shock pretreatment in rats. Psychopharmacol. 90:1986;90-94.
23. Martin P., Soubrie P., Simon P. The effect of monoamine oxidase inhibitors compared with classical tricyclic antidepressants on learned helplessness paradigm. Prog. Neuropsychopharmacol. Biol. Psychiat. 11:1987;1-7.
24. Martin P., Soubrie P., Puech A. J. Reversal of helpless behavior by serotonin uptake blockers in rats. Psychopharmacol. 101:1990;403-407.
25. Meltzer H. Y. Role of sertonin in depression. Ann. N.Y. Acad. Sci. 600:1990;486-499.
26. Meltzer H. Y. Beyond Serotonin. J. Clin. Psychiatry. 52:1991;58-62.
27. Minor R., Pelleymounter M. A., Maier S. F. Uncontrollable shock, forebrain norephinephrine and stimulus selection during choice escape learning. Psychobiology. 16:1988;135-145.
28. Morinobu S., Duman R. S. Induction of BDNF mRNA by electroconvulsive seizure (ECS) and antidepressants in rat frontal cortex. Soc. Neurosci. Abs. 19:1993;499.
29. Murua V. S., Molina V. A. Antidepressants reduce inactivity during both inescapable shock administration and shuttle box testing. Eur. J. Pharmacol. 204:1992;187-192.
30. Nawa H., Pelleymounter M. A., Carnahan J. Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain. J. Neurosci. 14:1994;3751-3765.
31. Nibuya M., Rydelek-Fitzgerald L., Morinobu S., Russel D. S., Nestler E. J., Duman R. S. Induction of BDNF and trkB by electroconvulsive seizure (ECS). Regional regulation and role of CREB Soc. Neurosci. Abs. 20:1994;1312.
32. Pelleymounter M. A., Cullen M. J., Wellman C. L. Characteristics of BDNF-induced weight loss. Exp. Neurol. 131:1995;229-238.
33. Petty F., Kramer G., Wilson L., Chae Y-L. Learned helplessness and in vivo hippocampal norepinephrine release. Pharmacol. Biochem. Behav. 46:1993;231-235.
34. Petty F., Kramer G., Wilson L. Learned helplessness induction decreases in vivo cortical serotonin release. Pharmacol. Biochem. Behav. 18:1993;649-650.
35. Petty F., Sherman A. D. A neurochemical differentiation between exposure to stress and the development of learned helplessness. Drug Dev. Res. 2:1982;43-45.
36. Porsolt R. D., LePichon M., Jalfre M. Depression; a new animal model sensitive to antidepressant treatments. Nature. 266:1977;730-731.
37. Porsolt R. D., Anton G., Blavet N., Jalfre M. Behavioral despair in rats. A new model sensitive to antidepressant treatment Eur. J. Pharmacol. 47:1978;379-384.
38. Porsolt R. D., Bertin A., Jalfre M. Behavioral despair in rats and mice. Strain diffferences and the effects of imipramine Eur. J. Pharmacol. 51:1978;291-295.
39. Porsolt R. D., Bertin A., Blavet N., Deniel M., Jalfre M. Immobility induced by forced swimming in rats. Effects of agents which modify central catecholamine and serotonin activity Eur. J. Pharmacol. 57:1979;201-210.
40. Potter W. Z., Manji H. K. Catecholamines in depression. An update Clin. Chem. 40:1994;279-287.
41. Sauer H., Fischer W., Nikkhah G., Wiegand S. J., Brundin P., Lindsay R. M., Bjorklund A. BDNF enhances function rather than survival of intrastriatal dopamine cell-rich grafts. Brain Res. 626:1993;37-44.
42. Schildkraut J. J. The catecholamine hypothesis of affective disorders. A review of supporting evidence Am. J. Psychiatry. 122:1965;509-522.
43. Seligman M. E. P., Beagley G. Learned helplessness in the rat. J. Comp. Physiol. Psychol. 88:1975;534-541.
44. Seligman M. E. P., Maier S. F. Failure to escape traumatic shock. J. Exp. Psychol. 74:1967;1-9.
45. Sherman A. D., Petty F. Neurochemical basis of action of antidepressants on learned helplessness. Behav. Neural Biol. 30:1980;119-134.
46. Sherman A. D., Petty F. Additivity of neurochemical changes in learned helplessness and imipramine. Behav. Neural Biol. 35:1982;344-353.
47. Sherman A. D., Sacquitne J. L., Petty F. Specifictiy of the learned helplessness model of depression. Pharmacol. Biochem. Behav. 16:1982;449-454.
48. Siuciak J. A., Altar C. A., Wiegand S. J., Lindsay R. M. Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3. Brain Res. 633:1994;326-330.
49. Siuciak J. A., Wong V., Pearsall D., Wiegand S. J., Lindsay R. M. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. Eur. J. Neurosci. 7:1995;663-670.
50. Siuciak J. A., Boylan C., Fritsche M., Altar C. A., Lindsay R. M. BDNF increases monoaminergic activity in rat brain follow- ing intracerebroventricular or intraparenchymal adminsitration. Brain Res. 710:1996;11-20.
51. Stahl S. M. Serotonergic mechanisms and the new antidepressants. Psychological Med. 23:1993;281-285.
52. Tork I. Raphe nuclei and serotonin containing systems. Paxinos G. The rat nervous system, Volume 2. Hindbrain and spinal cord. 1985;43-78 Academic Press, New York.
53. van Praag, H. M.: Neurotransmitters and CNS disease, Lancet 1259-1264; 1982.
54. Wahlestedt C., Ekman R., Widerlov E. NPY and the central nervous system. Distribution and possible relationship to neurological and psychiatric disorders Prog. Neuropsychopharmacol. Biol. Psychiatry. 13:1989;31-54.
55. Weber M. M., Emrich H. M. Current and historical concepts of opiate treatment in psychatric disorders. Intl. Clin. Psychopharmacol. 3:1988;255-266.
56. Wettstein J. G., Earley B., Junien J. L. Central nervous system pharmaoclogy of neuropeptide Y. Pharmacol. Ther. 65:1995;397-414.
57. Whitehouse W. G., Walker J., Margules D. L., Bersh P. J. Opiate antagonists overcome the learned helplessness effect but impair competent escape performance. Physiol. Behav. 30:1983;731-734.
58. Widerlov E., Lindstrom L. H., Wahlestedt C., Ekman R. NPY and peptide YY as possible CSF markers for major depression and schizophrenia, respectively. J. Psychiatr. Res. 22:1988;69-79.
59. Widerlov E., Heilig M., Ekman R., Wahlestedt C. NPY. Possible involvement in depression and anxiety Mutt V., Fuxe K., Hokfelt T. Nobel conference on NPY. 1989;331-342 Raven Press, New York.
60. 1A agonists measured with the forced swim test. Psychopharmacol. 101:1990;497-504.
61. Willner P. Dopamine and depression. A review of recent evidence. I. Empirical studies Brian Res. 287:1983;211-224.
62. Willner P. Dopamine and depression. A review of recent evidence. II. Theoretical approaches Brian Res. 287:1983;225-236.
63. Willner P. Dopamine and depression. A review of recent evidence. III. The effects of antidepressant treatments Brian Res. 287:1983;237-246.
64. Willner P. The validity of animals models of depression. Psychopharmacol. 83:1984;1-45.
65. Willner P. Animal models of anhedonia. Soubrie P. Anxiety, depression, and mania, Animal models. 1991;71-99 Psychiaric Disorders, Karger, Basel.
66. Willner, P.; Muscat, R.; Papp, M.; Sampson, D.: In: Willner, P.; Scheel-Kruger, J. eds. The mesolimbic dopamine system: From motivation to action. New York: Wiley; 1991:387-410.