Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility

Pharmacology Biochemistry and Behavior

Volumn 87, Issue 4, 2007, Pages 412-419

  Beckley, Ethan H ^a   Finn, Deborah A ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Allopregnanolone; Behavioral despair; Depression; Finasteride; GABA A receptor; Postpartum depression; Premenstrual syndrome; Progesterone withdrawal

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; FINASTERIDE; NEUROSTEROID; PROGESTERONE; STEROID 5ALPHA REDUCTASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG INHIBITION; DRUG WITHDRAWAL; FEMALE; FORCED SWIMMING TEST; IMMOBILIZATION; MOUSE; NONHUMAN; PREMENSTRUAL SYNDROME; PRIORITY JOURNAL; PROGESTERONE METABOLISM; PUERPERAL DEPRESSION; STATISTICAL SIGNIFICANCE; TREATMENT DURATION; TREATMENT WITHDRAWAL;

ANIMALS; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; FINASTERIDE; MICE; MICE, INBRED DBA; MOTOR ACTIVITY; PREGNANOLONE; PROGESTERONE; SUBSTANCE WITHDRAWAL SYNDROME; SWIMMING; TESTOSTERONE 5-ALPHA-REDUCTASE;

MUS; RODENTIA;

EID: 34547838202     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2007.05.017     Document Type: Article

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