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Volumn 72, Issue 3, 1996, Pages 641-653

Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by intrastriatal 6-hydroxydopamine in the rat

Author keywords

6 hydroxydopamine; degeneration; Parkinson's disease; paw reaching; striatum; substantia nigra

Indexed keywords

OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

EID: 0029981267     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00571-4     Document Type: Article
Times cited : (211)

References (39)
  • 1
    • 1542703727 scopus 로고
    • Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat
    • Agid Y., Javoy F. and Glowinski J. (1973) Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat. Nature 245, 150-151.
    • (1973) Nature , vol.245 , pp. 150-151
    • Agid, Y.1    Javoy, F.2    Glowinski, J.3
  • 2
    • 0023130088 scopus 로고
    • Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: Implications for behavioral recovery from brain injury
    • Altar C. A., Marien M. R. and Marshall J. F. (1987) Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: implications for behavioral recovery from brain injury. J. Neurochem. 48, 390-399.
    • (1987) J. Neurochem. , vol.48 , pp. 390-399
    • Altar, C.A.1    Marien, M.R.2    Marshall, J.F.3
  • 3
    • 0026081180 scopus 로고
    • Retrograde degeneration of nigrostriatal neurons induced by intrastriatal injection in rats
    • Berger K., Przedborski S. and Cadet J. L. (1991) Retrograde degeneration of nigrostriatal neurons induced by intrastriatal injection in rats. Brain Res. Bull. 26, 301-307.
    • (1991) Brain Res. Bull. , vol.26 , pp. 301-307
    • Berger, K.1    Przedborski, S.2    Cadet, J.L.3
  • 4
    • 0002196763 scopus 로고
    • Dopamine-containing systems in the CNS
    • Classical Transmitters in the CNS (eds Björklund A., Hökfelt T. and Kuhar M. J.) Elsevier, Amsterdam
    • Björklund A. and Lindvall O. (1984) Dopamine-containing systems in the CNS. In Handbook of Chemical Neuroanatomy. Vol. 2: Classical Transmitters in the CNS (eds Björklund A., Hökfelt T. and Kuhar M. J.), pp. 55-122. Elsevier, Amsterdam.
    • (1984) Handbook of Chemical Neuroanatomy , vol.2 , pp. 55-122
    • Björklund, A.1    Lindvall, O.2
  • 5
    • 0001496694 scopus 로고
    • A primate model of Parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Burns R. S., Chiueh C. C., Markey S. P., Ebert M. H., Jacobowitz D. M. and Kopin I. J. (1983) A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. natn. Acad. Sci. U.S.A. 890, 4546-4550.
    • (1983) Proc. Natn. Acad. Sci. U.S.A. , vol.890 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 6
    • 0025851603 scopus 로고
    • Long-term behavioral and biochemical effects of 6-hydroxydopamine injections in rat caudate-putamen
    • Cadet J. L., Last R., Kostic V., Przedborski S. and Jackson-Lewis V. (1991) Long-term behavioral and biochemical effects of 6-hydroxydopamine injections in rat caudate-putamen. Brain Res. Bull. 26, 707-713.
    • (1991) Brain Res. Bull. , vol.26 , pp. 707-713
    • Cadet, J.L.1    Last, R.2    Kostic, V.3    Przedborski, S.4    Jackson-Lewis, V.5
  • 7
    • 0017651245 scopus 로고
    • Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity
    • Creese I., Burt D. R. and Snyder S. H. (1977) Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity. Science 197, 596-598.
    • (1977) Science , vol.197 , pp. 596-598
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 9
    • 0001989283 scopus 로고
    • Evidence for the existence of monoamine neurons in the central nervous system I. Demonstration of monoamines in the cell bodies of brain stem neurons
    • Dahlström A. and Fuxe K. (1964) Evidence for the existence of monoamine neurons in the central nervous system I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta physiol. scand. Suppl. 232, 1-55.
    • (1964) Acta Physiol. Scand. , vol.232 , Issue.SUPPL. , pp. 1-55
    • Dahlström, A.1    Fuxe, K.2
  • 10
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S. and Cohen G. (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 31, 804-812.
    • (1992) Ann. Neurol. , vol.31 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 11
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley J. M. and Lees A. J. (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114, 2283-2301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 12
    • 0018830236 scopus 로고
    • Partial lesions of the dopaminergic nigrostriatal pathway in rat brain: Biochemical characterization
    • Hefti F., Melamed E. and Wurtman R. J. (1980) Partial lesions of the dopaminergic nigrostriatal pathway in rat brain: biochemical characterization. Brain Res. 195, 123-137.
    • (1980) Brain Res. , vol.195 , pp. 123-137
    • Hefti, F.1    Melamed, E.2    Wurtman, R.J.3
  • 13
    • 0025817092 scopus 로고
    • Degeneration of the nigral dopamine neurons after 6-hydroxydopamine injection into the rat striatum
    • Ichitani Y., Okamura H., Matsumoto Y., Nagatsu I. and Ibata Y. (1991) Degeneration of the nigral dopamine neurons after 6-hydroxydopamine injection into the rat striatum. Brain Res. 549, 350-353.
    • (1991) Brain Res. , vol.549 , pp. 350-353
    • Ichitani, Y.1    Okamura, H.2    Matsumoto, Y.3    Nagatsu, I.4    Ibata, Y.5
  • 14
    • 0028610569 scopus 로고
    • Biochemical and immunocytochemical changes induced by intrastriatal 6-hydroxydopamine injection in the rat nigrostriatal dopamine neuron system: Evidence for cell death in the substantia nigra
    • Ichitani Y., Okamura H., Nakahara D., Nagatsu I. and Ibata Y. (1994) Biochemical and immunocytochemical changes induced by intrastriatal 6-hydroxydopamine injection in the rat nigrostriatal dopamine neuron system: evidence for cell death in the substantia nigra. Expl. Neurol. 130, 269-278.
    • (1994) Expl. Neurol. , vol.130 , pp. 269-278
    • Ichitani, Y.1    Okamura, H.2    Nakahara, D.3    Nagatsu, I.4    Ibata, Y.5
  • 15
    • 0021017441 scopus 로고
    • Nigral dopaminergic mechanisms in drug-induced circling
    • Jackson E. A. and Kelly P. H. (1983) Nigral dopaminergic mechanisms in drug-induced circling. Brain Res. Bull. 11, 605-611.
    • (1983) Brain Res. Bull. , vol.11 , pp. 605-611
    • Jackson, E.A.1    Kelly, P.H.2
  • 16
    • 0026569594 scopus 로고
    • Aging produces a specific pattern of striatal dopamine loss: Implications for the etiology of idiopathic Parkinson's disease
    • Kish S. J., Shannak K., Rajput A., Deck J. H. N. and Hornykiewicz O. (1992) Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. J. Neurochem. 58, 642-648.
    • (1992) J. Neurochem. , vol.58 , pp. 642-648
    • Kish, S.J.1    Shannak, K.2    Rajput, A.3    Deck, J.H.N.4    Hornykiewicz, O.5
  • 17
    • 0025194362 scopus 로고
    • Nigral D1 and striatal D2 receptors mediate the behavioral effects of dopamine agonists
    • LaHoste G. J. and Marshall J. F. (1990) Nigral D1 and striatal D2 receptors mediate the behavioral effects of dopamine agonists. Behav. Brain Res. 38, 233-242.
    • (1990) Behav. Brain Res. , vol.38 , pp. 233-242
    • LaHoste, G.J.1    Marshall, J.F.2
  • 18
    • 0028236839 scopus 로고
    • Clinical observations on the rate of progression of idiopathic Parkinsonism and a mathematical model of pathogenesis: Part I. Clinical observations
    • Lee C. S., Schulzer M., Mak E., Snow B. J., Tsui J. K., Calne S., Hammerstad J. and Calne D. B. (1994) Clinical observations on the rate of progression of idiopathic Parkinsonism and a mathematical model of pathogenesis: part I. Clinical observations. Brain 117, 501-507.
    • (1994) Brain , vol.117 , pp. 501-507
    • Lee, C.S.1    Schulzer, M.2    Mak, E.3    Snow, B.J.4    Tsui, J.K.5    Calne, S.6    Hammerstad, J.7    Calne, D.B.8
  • 19
    • 0020509931 scopus 로고
    • Possible role of neuromelanin in the pathogenesis of Parkinson's disease
    • Mann D. M. and Yates P. O. (1983) Possible role of neuromelanin in the pathogenesis of Parkinson's disease. Mech. Agng Devl. 21, 193-203.
    • (1983) Mech. Agng Devl. , vol.21 , pp. 193-203
    • Mann, D.M.1    Yates, P.O.2
  • 20
    • 0026101797 scopus 로고
    • The 'staircase test': A measure of independent forelimb reaching and grasping abilities in rats
    • Montoya C. P., Campbell H. L., Pemberton K. D. and Dunnett S. B. (1991) The 'staircase test': a measure of independent forelimb reaching and grasping abilities in rats. J. Neurosci. Meth. 36, 2-3.
    • (1991) J. Neurosci. Meth. , vol.36 , pp. 2-3
    • Montoya, C.P.1    Campbell, H.L.2    Pemberton, K.D.3    Dunnett, S.B.4
  • 21
    • 0028360140 scopus 로고
    • Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model
    • Nikkhah G., Bentlage C., Cunningham M. G. and Björklund A. (1994) Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. J. Neurosci. 14, 3449-3461.
    • (1994) J. Neurosci. , vol.14 , pp. 3449-3461
    • Nikkhah, G.1    Bentlage, C.2    Cunningham, M.G.3    Björklund, A.4
  • 22
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow C. M. (1993) A radical hypothesis for neurodegeneration. Trends Neurosci. 16, 439-444.
    • (1993) Trends Neurosci. , vol.16 , pp. 439-444
    • Olanow, C.M.1
  • 23
    • 0027530638 scopus 로고
    • Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group (1993) Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med. 328, 176-183.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 176-183
  • 26
    • 0029015394 scopus 로고
    • Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine
    • Przedborski S., Levivier M., Jiang H., Ferreira M., Jackson-Lewis V., Donaldson D. and Togasaki D. M. (1995) Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine. Neuroscience 67, 631-647.
    • (1995) Neuroscience , vol.67 , pp. 631-647
    • Przedborski, S.1    Levivier, M.2    Jiang, H.3    Ferreira, M.4    Jackson-Lewis, V.5    Donaldson, D.6    Togasaki, D.M.7
  • 27
    • 0017082987 scopus 로고
    • Time course of nigrostriatal degeneration in Parkinson's disease
    • Riederer P. and Wuketich S. (1976) Time course of nigrostriatal degeneration in Parkinson's disease. J. neural Transm. 38, 277-301.
    • (1976) J. Neural Transm. , vol.38 , pp. 277-301
    • Riederer, P.1    Wuketich, S.2
  • 28
    • 0025772411 scopus 로고
    • Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants
    • Rioux L., Gaudin D. P., Gagnon C., DiPaolo T. and Bédard P. J. (1991) Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants. Neuroscience 44, 75-83.
    • (1991) Neuroscience , vol.44 , pp. 75-83
    • Rioux, L.1    Gaudin, D.P.2    Gagnon, C.3    DiPaolo, T.4    Bédard, P.J.5
  • 29
    • 0026589493 scopus 로고
    • Dopamine receptor interactions: Some implications for the treatment of Parkinson's disease
    • Robertson H. A. (1992) Dopamine receptor interactions: some implications for the treatment of Parkinson's disease. Trends Neurosci. 15, 201-206.
    • (1992) Trends Neurosci. , vol.15 , pp. 201-206
    • Robertson, H.A.1
  • 30
    • 0023948634 scopus 로고
    • Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: A microdialysis study in freely moving rats
    • Robinson T. E. and Whishaw I. Q. (1988) Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats. Brain Res. 450, 209-224.
    • (1988) Brain Res. , vol.450 , pp. 209-224
    • Robinson, T.E.1    Whishaw, I.Q.2
  • 31
    • 0029047329 scopus 로고
    • Glial cell line-derived neurotrophic factor but not transforming growth factor β3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
    • Sauer H., Rosenblad C. and Björklund A. (1995) Glial cell line-derived neurotrophic factor but not transforming growth factor β3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc. natl Acad. Sci. U.S.A. 92, 8935-8939.
    • (1995) Proc. Natl Acad. Sci. U.S.A. , vol.92 , pp. 8935-8939
    • Sauer, H.1    Rosenblad, C.2    Björklund, A.3
  • 32
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-OHDA: A combined retrograde tracing and immunocytochemical study in the rat
    • Sauer H. and Oertel W. H. (1994) Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-OHDA: a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59, 401-415.
    • (1994) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 34
    • 0025118725 scopus 로고
    • Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: A model for Parkinson's disease
    • Sundström E., Fredriksson A. and Archer T. (1990) Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease. Brain Res. 528, 181-188.
    • (1990) Brain Res. , vol.528 , pp. 181-188
    • Sundström, E.1    Fredriksson, A.2    Archer, T.3
  • 35
    • 0014376793 scopus 로고
    • 6-Hydroxydopamine induced degeneration of central monoamine neurons
    • Ungerstedt U. (1968) 6-Hydroxydopamine induced degeneration of central monoamine neurons. Eur. J. Pharmac. 5, 107-110.
    • (1968) Eur. J. Pharmac. , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 36
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt U. and Arbuthnott G. W. (1970) Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res. 24, 485-493.
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 37
    • 0028609847 scopus 로고
    • Oxygen free radicals and neurodegeneration in Parkinson's disease: A role for nitric oxide
    • Youdim M. B., Lavie L. and Riederer P. (1994) Oxygen free radicals and neurodegeneration in Parkinson's disease: a role for nitric oxide. Ann. N.Y. Acad. Sci. 738, 64-68.
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 64-68
    • Youdim, M.B.1    Lavie, L.2    Riederer, P.3
  • 38
    • 0023898407 scopus 로고
    • In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC
    • Zetterström T., Sharp T., Collin A. K. and Ungerstedt U. (1988) In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC. Eur. J. Pharmac. 148, 327-334.
    • (1988) Eur. J. Pharmac. , vol.148 , pp. 327-334
    • Zetterström, T.1    Sharp, T.2    Collin, A.K.3    Ungerstedt, U.4
  • 39
    • 0025373167 scopus 로고
    • Compensations after lesions of central dopaminergic neurons: Some clinical and basic implications
    • Zigmond M. J., Abercrombie E. D., Berger T. W., Grace A. A. and Stricker E. M. (1990) Compensations after lesions of central dopaminergic neurons: some clinical and basic implications. Trends Neurosci. 13, 290-296.
    • (1990) Trends Neurosci. , vol.13 , pp. 290-296
    • Zigmond, M.J.1    Abercrombie, E.D.2    Berger, T.W.3    Grace, A.A.4    Stricker, E.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.