메뉴 건너뛰기




Volumn 24, Issue 7, 2007, Pages 495-517

Role of GABA in anxiety and depression

Author keywords

Anxiety; Benzodiazepine receptors; Common pathogenesis; Depression; GABA

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINO 3 PHENYLBUTYRIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ADINAZOLAM; ALCOHOL; ALPRAZOLAM; AMINOOXYACETIC ACID; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BACLOFEN; BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; DIAZEPAM; GABAPENTIN; MUSCIMOL; NEUROTRANSMITTER; OXCARBAZEPINE; PENTOBARBITAL; PROGABIDE; PROGESTERONE; SEROTONIN UPTAKE INHIBITOR; TIAGABINE; VALPROIC ACID; VIGABATRIN;

EID: 36048976944     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20262     Document Type: Review
Times cited : (399)

References (344)
  • 1
    • 0024582091 scopus 로고
    • GABA-mediated modification of despair behavior in mice
    • Aley KO, Kulkarni SK. 1989. GABA-mediated modification of despair behavior in mice. Naunyn Schmied Arch Pharmacol 339:306-311.
    • (1989) Naunyn Schmied Arch Pharmacol , vol.339 , pp. 306-311
    • Aley, K.O.1    Kulkarni, S.K.2
  • 3
    • 0018080816 scopus 로고
    • Single neuron analysis of the midbrain tegmentum: Rostral mesencephalic reticulotomy of pain relief
    • Amano K, Tanikama T, Iseki H, Kawabatake H, Notani M, Kawamura H. 1978. Single neuron analysis of the midbrain tegmentum: rostral mesencephalic reticulotomy of pain relief. Appl Neurophysiol 41:66-78.
    • (1978) Appl Neurophysiol , vol.41 , pp. 66-78
    • Amano, K.1    Tanikama, T.2    Iseki, H.3    Kawabatake, H.4    Notani, M.5    Kawamura, H.6
  • 4
    • 0032899957 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor in depression and anxiety disorders
    • Arborelius L, Owens MJ, Plotsky PM, Nemeroff CB. 1999. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol 160:1-12.
    • (1999) J Endocrinol , vol.160 , pp. 1-12
    • Arborelius, L.1    Owens, M.J.2    Plotsky, P.M.3    Nemeroff, C.B.4
  • 5
    • 0031438398 scopus 로고    scopus 로고
    • Anhedonia and chronic mild stress model in depression
    • Argyropoulos SV, Nutt DJ. 1997. Anhedonia and chronic mild stress model in depression. Psychopharmacology 134:333-336.
    • (1997) Psychopharmacology , vol.134 , pp. 333-336
    • Argyropoulos, S.V.1    Nutt, D.J.2
  • 6
    • 0033383112 scopus 로고    scopus 로고
    • The use of benzodiazepines in anxiety and other disorders
    • Argyropoulos SV, Nutt DJ. 1999. The use of benzodiazepines in anxiety and other disorders. Eur Neuropsychopharmacol 9(Suppl 6):S407-S412.
    • (1999) Eur Neuropsychopharmacol , vol.9 , Issue.SUPPL. 6
    • Argyropoulos, S.V.1    Nutt, D.J.2
  • 7
    • 0034351295 scopus 로고    scopus 로고
    • The psychobiology of anxiolytic drug. 2. Pharmacological treatments of anxiety
    • Argyropoulos SV, Sandford JJ, Nutt DJ. 2000. The psychobiology of anxiolytic drug. 2. Pharmacological treatments of anxiety. Pharmacol Ther 88:213-227.
    • (2000) Pharmacol Ther , vol.88 , pp. 213-227
    • Argyropoulos, S.V.1    Sandford, J.J.2    Nutt, D.J.3
  • 8
    • 0142122123 scopus 로고    scopus 로고
    • Anxioselective compounds acting at the GABAa receptor benzodiazepine binding site
    • Atack JR. 2003. Anxioselective compounds acting at the GABAa receptor benzodiazepine binding site. Curr Drug Targ CNS Neurol Disord 2:213-232.
    • (2003) Curr Drug Targ CNS Neurol Disord , vol.2 , pp. 213-232
    • Atack, J.R.1
  • 9
    • 20344392658 scopus 로고    scopus 로고
    • The benzodiazepine binding site of GABA-A receptors as a target for the development of novel anxiolytics
    • Atack JR. 2005. The benzodiazepine binding site of GABA-A receptors as a target for the development of novel anxiolytics. Expert Opin Investig Drugs 14:599-616.
    • (2005) Expert Opin Investig Drugs , vol.14 , pp. 599-616
    • Atack, J.R.1
  • 11
    • 0021129429 scopus 로고
    • Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action
    • Audi EA, Graeff FG. 1984. Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action. Eur J Pharmacol 103:279-285.
    • (1984) Eur J Pharmacol , vol.103 , pp. 279-285
    • Audi, E.A.1    Graeff, F.G.2
  • 12
    • 0023160230 scopus 로고
    • GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA
    • Audi EA, Graeff FG. 1987. GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA. Eur J Pharmacol 135: 225-229.
    • (1987) Eur J Pharmacol , vol.135 , pp. 225-229
    • Audi, E.A.1    Graeff, F.G.2
  • 13
    • 0035171425 scopus 로고    scopus 로고
    • Intra- and interstrain differences in models of "behavioral despair.". Pharmacol Biochem
    • Bai F, Li M, Clay M, Lindstrom T, Skolnick P. 2001. Intra- and interstrain differences in models of "behavioral despair.". Pharmacol Biochem Behav 70:187-192.
    • (2001) Behav , vol.70 , pp. 187-192
    • Bai, F.1    Li, M.2    Clay, M.3    Lindstrom, T.4    Skolnick, P.5
  • 14
    • 0034132105 scopus 로고    scopus 로고
    • Interactions between distinct GABA(A) circuits in hippocampus
    • Banks MI, White JA, Pearce RA. 2000. Interactions between distinct GABA(A) circuits in hippocampus. Neuron 25:449-457.
    • (2000) Neuron , vol.25 , pp. 449-457
    • Banks, M.I.1    White, J.A.2    Pearce, R.A.3
  • 15
    • 27944502881 scopus 로고    scopus 로고
    • Fear extinction in rodents: Basic insight to clinical promise
    • Barad M. 2005. Fear extinction in rodents: basic insight to clinical promise. Curr Opin Neurobiol 15:710-715.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 710-715
    • Barad, M.1
  • 18
    • 0021235312 scopus 로고
    • Experimental basis for the antidepressant action of the GABA receptor agonist progabide
    • Bartholini G. 1984. Experimental basis for the antidepressant action of the GABA receptor agonist progabide. Neurosci Lett 47: 351-355.
    • (1984) Neurosci Lett , vol.47 , pp. 351-355
    • Bartholini, G.1
  • 19
    • 11844283307 scopus 로고    scopus 로고
    • Anxiety and panic: From human studies to animal research and back
    • Battaglia M, Ogliari A. 2005. Anxiety and panic: from human studies to animal research and back. Neurosci Biobehav Rev 29:169-179.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 169-179
    • Battaglia, M.1    Ogliari, A.2
  • 20
    • 0032540204 scopus 로고    scopus 로고
    • The effect of oxcarbazepine on behavioral despair and learned helplessness
    • Beijamini V, Skalisz LL, Joca SR, Andreatini R. 1998. The effect of oxcarbazepine on behavioral despair and learned helplessness. Eur J Pharmacol 347:23-27.
    • (1998) Eur J Pharmacol , vol.347 , pp. 23-27
    • Beijamini, V.1    Skalisz, L.L.2    Joca, S.R.3    Andreatini, R.4
  • 21
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: Endogenous regulators of the GABA(A) receptor
    • Beleih D, Lambert JJ. 2005. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci 6:565-575.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 565-575
    • Beleih, D.1    Lambert, J.J.2
  • 23
    • 0031266021 scopus 로고    scopus 로고
    • A pharmaco-ethological study of the GABA-ergic mechanisms regulating the depression-like behavior of mice
    • Belozertseva IV, Andreev BV. 1997. A pharmaco-ethological study of the GABA-ergic mechanisms regulating the depression-like behavior of mice. Zh VND Im I P Pavlova 47:1024-1031.
    • (1997) Zh VND Im I P Pavlova , vol.47 , pp. 1024-1031
    • Belozertseva, I.V.1    Andreev, B.V.2
  • 24
    • 0034882602 scopus 로고    scopus 로고
    • Rodent models of anxiety-like behaviors: Are they predictive for compounds acting via non-benzodiazepine mechanisms?
    • Belzung C. 2001. Rodent models of anxiety-like behaviors: are they predictive for compounds acting via non-benzodiazepine mechanisms? Curr Opin Investig Drugs 2:1108-1111.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 1108-1111
    • Belzung, C.1
  • 25
    • 0034950048 scopus 로고    scopus 로고
    • Behavioral effects of the new anticonvulsants
    • Besag FM. 2001. Behavioral effects of the new anticonvulsants. Drug Saf 24:513-536.
    • (2001) Drug Saf , vol.24 , pp. 513-536
    • Besag, F.M.1
  • 26
    • 1642446033 scopus 로고    scopus 로고
    • Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor
    • Bhagwagar Z, Wylezinska M, Taylor M, Jezzard P, Matthews PM, Cowen PJ. 2004. Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor. Am J Psychiatry 161:368-370.
    • (2004) Am J Psychiatry , vol.161 , pp. 368-370
    • Bhagwagar, Z.1    Wylezinska, M.2    Taylor, M.3    Jezzard, P.4    Matthews, P.M.5    Cowen, P.J.6
  • 28
    • 0035946192 scopus 로고    scopus 로고
    • Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder
    • Bjork JM, Moeller FG, Kramer GL, Kram M, Suris A, Rush AJ, Petty E 2001. Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder. Psychiatry Res 101:131-136.
    • (2001) Psychiatry Res , vol.101 , pp. 131-136
    • Bjork, J.M.1    Moeller, F.G.2    Kramer, G.L.3    Kram, M.4    Suris, A.5    Rush, A.J.6    Petty, E.7
  • 30
    • 0022649757 scopus 로고
    • Effect of GABAergic drugs in the behavioral 'despair' test in rats
    • Borsini F, Evangelista S, Meli A. 1986. Effect of GABAergic drugs in the behavioral 'despair' test in rats. Eur J Pharmacol 121: 265-268.
    • (1986) Eur J Pharmacol , vol.121 , pp. 265-268
    • Borsini, F.1    Evangelista, S.2    Meli, A.3
  • 32
    • 0036053186 scopus 로고    scopus 로고
    • Do animal models of anxiety predict anxiolytic-like effects of antidepressants?
    • Borsini F, Podhorna J, Marazziti D. 2002. Do animal models of anxiety predict anxiolytic-like effects of antidepressants? Psychopharmacology 163:121-141.
    • (2002) Psychopharmacology , vol.163 , pp. 121-141
    • Borsini, F.1    Podhorna, J.2    Marazziti, D.3
  • 33
    • 0037100295 scopus 로고    scopus 로고
    • rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest
    • Boshuisen ML, Ter Horst GJ, Paans AM, Reinders AA, den Boer JA. 2002. rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest. Biol Psychiatry 52:126-135.
    • (2002) Biol Psychiatry , vol.52 , pp. 126-135
    • Boshuisen, M.L.1    Ter Horst, G.J.2    Paans, A.M.3    Reinders, A.A.4    den Boer, J.A.5
  • 34
    • 0026321406 scopus 로고
    • Clonidine as a sensitizing agent in the forced swimming test for revealing antidepressant activity
    • Bourin M, Colombel MC, Malinge M, Bradwejn J. 1991. Clonidine as a sensitizing agent in the forced swimming test for revealing antidepressant activity. J Psychiatry Neurosci 16:199-203.
    • (1991) J Psychiatry Neurosci , vol.16 , pp. 199-203
    • Bourin, M.1    Colombel, M.C.2    Malinge, M.3    Bradwejn, J.4
  • 35
    • 0019991356 scopus 로고
    • Enhancing GABAergic transmission reverses the aversive state in rats induced by electrical stimulation of the periaqueductal grey region
    • Bovier P, Broekkamp CL, Lloyd KG. 1982. Enhancing GABAergic transmission reverses the aversive state in rats induced by electrical stimulation of the periaqueductal grey region. Brain Res 248: 313-320.
    • (1982) Brain Res , vol.248 , pp. 313-320
    • Bovier, P.1    Broekkamp, C.L.2    Lloyd, K.G.3
  • 37
    • 0037470237 scopus 로고    scopus 로고
    • The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: Empirical and conceptual considerations
    • Brandao ML, Troncoso AC, de Souza Silva MA, Huston JP. 2003. The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations. Eur J Pharmacol 463:225-233.
    • (2003) Eur J Pharmacol , vol.463 , pp. 225-233
    • Brandao, M.L.1    Troncoso, A.C.2    de Souza Silva, M.A.3    Huston, J.P.4
  • 39
    • 0032723933 scopus 로고    scopus 로고
    • Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder
    • Bremner JD, Narayan M, Staib LH, Southwick SM, McGlashan T, Charney DS. 1999. Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. Am J Psychiatry 156:1787-1795.
    • (1999) Am J Psychiatry , vol.156 , pp. 1787-1795
    • Bremner, J.D.1    Narayan, M.2    Staib, L.H.3    Southwick, S.M.4    McGlashan, T.5    Charney, D.S.6
  • 41
    • 0033932223 scopus 로고    scopus 로고
    • Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder
    • Bremner JD, Innis RB, Southwick SM, Staib L, Zoghbi S, Charney DS. 2000b. Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. Am J Psychiatry 157:1120-1126.
    • (2000) Am J Psychiatry , vol.157 , pp. 1120-1126
    • Bremner, J.D.1    Innis, R.B.2    Southwick, S.M.3    Staib, L.4    Zoghbi, S.5    Charney, D.S.6
  • 42
    • 14544276838 scopus 로고    scopus 로고
    • Alterations in GABAergic function following forced swimming stress
    • Briones-Aranda A, Rocha L, Picazo O. 2005. Alterations in GABAergic function following forced swimming stress. Pharmacol Biochem Behav 80:463-470.
    • (2005) Pharmacol Biochem Behav , vol.80 , pp. 463-470
    • Briones-Aranda, A.1    Rocha, L.2    Picazo, O.3
  • 44
    • 36049008888 scopus 로고    scopus 로고
    • Panicolytic-like effect induced by the stimulation of GABAA and GABAB receptors in the dorsal periaqueductal grey of rats
    • Bueno CH, Zangrossi H Jr, Nogueira RL, Soares VP, Viana MB. 2005a. Panicolytic-like effect induced by the stimulation of GABAA and GABAB receptors in the dorsal periaqueductal grey of rats. Behav Brain Res 21:65-72.
    • (2005) Behav Brain Res , vol.21 , pp. 65-72
    • Bueno, C.H.1    Zangrossi Jr, H.2    Nogueira, R.L.3    Soares, V.P.4    Viana, M.B.5
  • 45
    • 27944451493 scopus 로고    scopus 로고
    • The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests
    • Bueno CH, Zangrossi H Jr, Viana MB. 2005b. The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests. Braz J Med Biol Res 38:1697-1701.
    • (2005) Braz J Med Biol Res , vol.38 , pp. 1697-1701
    • Bueno, C.H.1    Zangrossi Jr, H.2    Viana, M.B.3
  • 48
    • 0023881330 scopus 로고
    • Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography
    • Caldecott-Hazard S, Mazziotta J, Phelps M. 1988. Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography. J Neurosci 8:1951-1961.
    • (1988) J Neurosci , vol.8 , pp. 1951-1961
    • Caldecott-Hazard, S.1    Mazziotta, J.2    Phelps, M.3
  • 49
    • 2942668431 scopus 로고    scopus 로고
    • Maternal behavior regulates benzodiazepine/GABAA receptor subunit expression in brain regions associated with fear in BALB/c and C57BL/6 mice
    • Caldji C, Diorio J, Anisman H, Meaney MJ. 2004. Maternal behavior regulates benzodiazepine/GABAA receptor subunit expression in brain regions associated with fear in BALB/c and C57BL/6 mice. Neuropsychopharmacology 29:1344-1352.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1344-1352
    • Caldji, C.1    Diorio, J.2    Anisman, H.3    Meaney, M.J.4
  • 51
    • 0027729872 scopus 로고
    • Effects of desipramine and alprazolam in the forced swim test in rats after long-lasting termination of chronic exposure to Picrotoxin and pentylenetetrazol
    • Cannizzaro G, Flugy A, Cannizzaro C, Gagliano M, Sabatino M. 1993. Effects of desipramine and alprazolam in the forced swim test in rats after long-lasting termination of chronic exposure to Picrotoxin and pentylenetetrazol. Eur Neuropsychopharmacol 3: 477-484.
    • (1993) Eur Neuropsychopharmacol , vol.3 , pp. 477-484
    • Cannizzaro, G.1    Flugy, A.2    Cannizzaro, C.3    Gagliano, M.4    Sabatino, M.5
  • 52
    • 26844489352 scopus 로고    scopus 로고
    • Etiological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on
    • Carobrez AP, Bertoglio LJ. 2005. Etiological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on. Neurosci Biobehav Rev 29:1193-1205.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 1193-1205
    • Carobrez, A.P.1    Bertoglio, L.J.2
  • 53
  • 54
    • 26444444721 scopus 로고    scopus 로고
    • GABAA receptor γ2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines
    • Chandra D, Korpi ER, Miralies CP, De Blas AL, Homanics GE. 2005. GABAA receptor γ2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines. BMC Neurosci 6:30.
    • (2005) BMC Neurosci , vol.6 , pp. 30
    • Chandra, D.1    Korpi, E.R.2    Miralies, C.P.3    De Blas, A.L.4    Homanics, G.E.5
  • 55
    • 0037237459 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy studies of GABA in neuropsychiatrie disorders
    • Chang L, Cloak CC, Ernst T. 2003. Magnetic resonance spectroscopy studies of GABA in neuropsychiatrie disorders. J Clin Psychiatry 64(Suppl 3):7-14.
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 3 , pp. 7-14
    • Chang, L.1    Cloak, C.C.2    Ernst, T.3
  • 56
    • 0036675363 scopus 로고    scopus 로고
    • GABA-A receptor complex and memory processes
    • Chapouthier G, Venault P. 2002. GABA-A receptor complex and memory processes. Curr Top Med Chem 2:841-851.
    • (2002) Curr Top Med Chem , vol.2 , pp. 841-851
    • Chapouthier, G.1    Venault, P.2
  • 57
    • 12144257575 scopus 로고    scopus 로고
    • Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction
    • Chhatwal JP, Myers KM, Ressler KJ, Davis M. 2005. Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction. J Neurosci 25:502-506.
    • (2005) J Neurosci , vol.25 , pp. 502-506
    • Chhatwal, J.P.1    Myers, K.M.2    Ressler, K.J.3    Davis, M.4
  • 58
    • 0023706886 scopus 로고
    • Benzodiazepine inverse agonist FG-7142-induced delayed behavioral depression in mice
    • Chopra K, Kunchandy J, Kulkarni SK. 1988. Benzodiazepine inverse agonist FG-7142-induced delayed behavioral depression in mice. Arch Int Pharmacodyn Ther 294:56-63.
    • (1988) Arch Int Pharmacodyn Ther , vol.294 , pp. 56-63
    • Chopra, K.1    Kunchandy, J.2    Kulkarni, S.K.3
  • 62
    • 29344472813 scopus 로고    scopus 로고
    • Tiagabin for post-traumatic stress disorder: Effect of open-label and double-blind discontinuation treatment
    • Connor KM, Davidson JRT, Weisler RH, Zhang W, Abraham K. 2006. Tiagabin for post-traumatic stress disorder: effect of open-label and double-blind discontinuation treatment. Psychopharmacology 184:21-25.
    • (2006) Psychopharmacology , vol.184 , pp. 21-25
    • Connor, K.M.1    Davidson, J.R.T.2    Weisler, R.H.3    Zhang, W.4    Abraham, K.5
  • 63
    • 0032535748 scopus 로고    scopus 로고
    • Brain circuits in panic disorder
    • Coplan JD, Lydiard RB. 1998. Brain circuits in panic disorder. Biol Psychiatry 44:1264-1276.
    • (1998) Biol Psychiatry , vol.44 , pp. 1264-1276
    • Coplan, J.D.1    Lydiard, R.B.2
  • 64
    • 0041471163 scopus 로고    scopus 로고
    • Tiagabine for the treatment of anxiety
    • Crane D. 2003. Tiagabine for the treatment of anxiety. Depress Anxiety 18:51-52.
    • (2003) Depress Anxiety , vol.18 , pp. 51-52
    • Crane, D.1
  • 65
    • 0033578272 scopus 로고    scopus 로고
    • Behavioral phenotyping of transgenic and knockout mice: Experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests
    • Crawley JN. 1999. Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res 835:18-26.
    • (1999) Brain Res , vol.835 , pp. 18-26
    • Crawley, J.N.1
  • 68
    • 11844285655 scopus 로고    scopus 로고
    • Opportunities to discover genes regulating depression and antidepressant response from rodent behavioral genetics
    • Crowley JJ, Lucki I. 2005. Opportunities to discover genes regulating depression and antidepressant response from rodent behavioral genetics. Curr Pharm Design 11:157-169.
    • (2005) Curr Pharm Design , vol.11 , pp. 157-169
    • Crowley, J.J.1    Lucki, I.2
  • 69
    • 30944439522 scopus 로고    scopus 로고
    • Unravelling the brain targets of gamma-hydroxybutyric acid
    • Crunelli V, Emri Z, Leresche N. 2006. Unravelling the brain targets of gamma-hydroxybutyric acid. Curr Opin Pharmacol 6:1-9.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 1-9
    • Crunelli, V.1    Emri, Z.2    Leresche, N.3
  • 70
    • 26044460006 scopus 로고    scopus 로고
    • The ascent of mouse: Advances in modelling human depression and anxiety
    • Cryan JF, Holmes A. 2005. The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 4:775-790.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 71
    • 11144230982 scopus 로고    scopus 로고
    • Don't worry "B" happy: A role for GABAB receptors in anxiety and depression
    • Cryan JF, Kaupmann K. 2005. Don't worry "B" happy: a role for GABAB receptors in anxiety and depression. Trends Pharmacol Sci 26: 36-43.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 36-43
    • Cryan, J.F.1    Kaupmann, K.2
  • 72
    • 2042546746 scopus 로고    scopus 로고
    • In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice
    • Cryan JF, Mombereau C. 2004. In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice. Mol Psychiatry 9:326-357.
    • (2004) Mol Psychiatry , vol.9 , pp. 326-357
    • Cryan, J.F.1    Mombereau, C.2
  • 73
    • 0036570222 scopus 로고    scopus 로고
    • Assessing antidepressant activity in rodents: Recent developments and future needs
    • Cryan JF, Markou A, Lucki I. 2002. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci 23:238-245.
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 238-245
    • Cryan, J.F.1    Markou, A.2    Lucki, I.3
  • 74
    • 19944418868 scopus 로고    scopus 로고
    • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
    • Cryan JF, Valentino RJ, Lucki I. 2005. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev 29: 547-569.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 547-569
    • Cryan, J.F.1    Valentino, R.J.2    Lucki, I.3
  • 76
    • 0029853759 scopus 로고    scopus 로고
    • GABAergic influences on plus-maze behavior in mice
    • Dalvi A, Rodgers RJ. 1996. GABAergic influences on plus-maze behavior in mice. Psychopharmacology 128:380-397.
    • (1996) Psychopharmacology , vol.128 , pp. 380-397
    • Dalvi, A.1    Rodgers, R.J.2
  • 77
    • 0034993139 scopus 로고    scopus 로고
    • Effects of gonadal steroids on peripheral benzodiazepine receptor density in women with PMS and controls
    • Daly RC, Schmidt PJ, Davis CL, Danaceau MA, Rubinow DR. 2001. Effects of gonadal steroids on peripheral benzodiazepine receptor density in women with PMS and controls. Psychoneuroendocrinology 26:539-549.
    • (2001) Psychoneuroendocrinology , vol.26 , pp. 539-549
    • Daly, R.C.1    Schmidt, P.J.2    Davis, C.L.3    Danaceau, M.A.4    Rubinow, D.R.5
  • 78
    • 0036153246 scopus 로고    scopus 로고
    • Anxiety and affective style: Role of prefrontal cortex and amygdala
    • Davidson RJ. 2002. Anxiety and affective style: role of prefrontal cortex and amygdala. Biol Psychiatry 51:68-80.
    • (2002) Biol Psychiatry , vol.51 , pp. 68-80
    • Davidson, R.J.1
  • 80
    • 0141829702 scopus 로고    scopus 로고
    • The role of GABAA receptors in mediating the effects of alcohol in the central nervous system
    • Davies M. 2003. The role of GABAA receptors in mediating the effects of alcohol in the central nervous system. J Psychiatry Neurosci 28:263-274.
    • (2003) J Psychiatry Neurosci , vol.28 , pp. 263-274
    • Davies, M.1
  • 81
    • 0035137947 scopus 로고    scopus 로고
    • The amygdala: Vigilance and emotion
    • Davis M, Whalen PJ. 2001. The amygdala: vigilance and emotion. Mol Psychiatry 6:13-34.
    • (2001) Mol Psychiatry , vol.6 , pp. 13-34
    • Davis, M.1    Whalen, P.J.2
  • 82
    • 4444304974 scopus 로고    scopus 로고
    • A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: Implications for animal models of anxiety and depression
    • De La Garza, Mahoney JJ. 2004. A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression. Brain Res 1021: 209-218.
    • (2004) Brain Res , vol.1021 , pp. 209-218
    • La Garza, D.1    Mahoney, J.J.2
  • 83
    • 0028167980 scopus 로고
    • Antidepressant-induced modulation of GABAA receptors and beta-adrenoceptors but not GABAB receptors in the frontal cortex of olfactory bulbectomised rats
    • Dennis T, Beauchemin V, Lavoie N. 1994. Antidepressant-induced modulation of GABAA receptors and beta-adrenoceptors but not GABAB receptors in the frontal cortex of olfactory bulbectomised rats. Eur J Pharmacol 262:143-148.
    • (1994) Eur J Pharmacol , vol.262 , pp. 143-148
    • Dennis, T.1    Beauchemin, V.2    Lavoie, N.3
  • 84
    • 0032917710 scopus 로고    scopus 로고
    • Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice
    • Dong E, Matsumoto K, Tohda M, Kaneko Y, Watanabe H. 1999. Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice. Neurosci Res 33: 171-177.
    • (1999) Neurosci Res , vol.33 , pp. 171-177
    • Dong, E.1    Matsumoto, K.2    Tohda, M.3    Kaneko, Y.4    Watanabe, H.5
  • 85
    • 0036202062 scopus 로고    scopus 로고
    • Mouse lines differing in sensitivity to beta-CCM differ in tasks used for testing antidepressants
    • Do-Rego JC, Suaudeau C, Chapouthier G, Costentin J. 2002. Mouse lines differing in sensitivity to beta-CCM differ in tasks used for testing antidepressants. Pharmacol Biochem Behav 72:411-416.
    • (2002) Pharmacol Biochem Behav , vol.72 , pp. 411-416
    • Do-Rego, J.C.1    Suaudeau, C.2    Chapouthier, G.3    Costentin, J.4
  • 87
    • 0032780310 scopus 로고    scopus 로고
    • Prefrontal cortical-amygdalar metabolism in major depression
    • Drevets WC. 1999. Prefrontal cortical-amygdalar metabolism in major depression. Ann N Y Acad Sci 877:614-637.
    • (1999) Ann N Y Acad Sci , vol.877 , pp. 614-637
    • Drevets, W.C.1
  • 88
    • 0347991778 scopus 로고    scopus 로고
    • cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs
    • Drigues N, Poltyrev T, Bejar C, Weinstock M, Youdim MB. 2003. cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs. J Neural Transm 110: 1413-1436.
    • (2003) J Neural Transm , vol.110 , pp. 1413-1436
    • Drigues, N.1    Poltyrev, T.2    Bejar, C.3    Weinstock, M.4    Youdim, M.B.5
  • 90
    • 0024336510 scopus 로고
    • Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy
    • Drugan RC, Morrow AL, Weizman R, Weizman A, Deutsch SI, Crawley JN, Paul SM. 1989. Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy. Brain Res 487:45-51.
    • (1989) Brain Res , vol.487 , pp. 45-51
    • Drugan, R.C.1    Morrow, A.L.2    Weizman, R.3    Weizman, A.4    Deutsch, S.I.5    Crawley, J.N.6    Paul, S.M.7
  • 91
    • 0027787436 scopus 로고
    • Decreased forebrain [35S]TBPS binding and increased [3H]muscimol binding in rats that do not develop stress-induced behavioral depression
    • Drugan RC, Paul SM, Crawley JN. 1993. Decreased forebrain [35S]TBPS binding and increased [3H]muscimol binding in rats that do not develop stress-induced behavioral depression. Brain Res 631:270-276.
    • (1993) Brain Res , vol.631 , pp. 270-276
    • Drugan, R.C.1    Paul, S.M.2    Crawley, J.N.3
  • 92
    • 13444257817 scopus 로고    scopus 로고
    • Steroids, neuroactive steroids and neurosteroids in psychopathology
    • Dubrovsky BO. 2005. Steroids, neuroactive steroids and neurosteroids in psychopathology. Prog Neuropsychopharmacol Biol Psychiatry 29:169-192.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 169-192
    • Dubrovsky, B.O.1
  • 95
    • 0042694131 scopus 로고    scopus 로고
    • Pharmacogenomics of alcohol response and addiction
    • Enoch MA. 2003. Pharmacogenomics of alcohol response and addiction. Am J Pharmacogenomics 3:217-232.
    • (2003) Am J Pharmacogenomics , vol.3 , pp. 217-232
    • Enoch, M.A.1
  • 97
    • 0038279994 scopus 로고    scopus 로고
    • Glucocorticoid regulation of diverse cognitive functions in normal and pathological emotional states
    • Erickson K, Drevets W, Schulkin J. 2003. Glucocorticoid regulation of diverse cognitive functions in normal and pathological emotional states. Neurosci Biobehav Rev 27:233-246.
    • (2003) Neurosci Biobehav Rev , vol.27 , pp. 233-246
    • Erickson, K.1    Drevets, W.2    Schulkin, J.3
  • 100
    • 0037151271 scopus 로고    scopus 로고
    • Participation of the lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone in the forced swimming test (FST)
    • Estrada-Camarena E, Contreras CM, Saavedra M, Luna-Baltazar I, Lopez-Rubalcava C. 2002. Participation of the lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone in the forced swimming test (FST). Behav Brain Res 134:175-183.
    • (2002) Behav Brain Res , vol.134 , pp. 175-183
    • Estrada-Camarena, E.1    Contreras, C.M.2    Saavedra, M.3    Luna-Baltazar, I.4    Lopez-Rubalcava, C.5
  • 101
    • 9244249796 scopus 로고    scopus 로고
    • GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 and Reelin proteins in cerebellum
    • Fatemi SH, Stary JM, Earle JA, Araghi-Nikham M, Eagan E. 2005. GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 and Reelin proteins in cerebellum. Schizophr Res 72:109-122.
    • (2005) Schizophr Res , vol.72 , pp. 109-122
    • Fatemi, S.H.1    Stary, J.M.2    Earle, J.A.3    Araghi-Nikham, M.4    Eagan, E.5
  • 103
    • 0035504503 scopus 로고    scopus 로고
    • GABAA receptor β3 subunit gene and psychiatric morbidity in a post-traumatic stress disorder population
    • Feusner J, Ritchie T, Lawford B, Young RM, Kann B, Nobre EP. 2001. GABAA receptor β3 subunit gene and psychiatric morbidity in a post-traumatic stress disorder population. Psychiatry Res 104: 109-117.
    • (2001) Psychiatry Res , vol.104 , pp. 109-117
    • Feusner, J.1    Ritchie, T.2    Lawford, B.3    Young, R.M.4    Kann, B.5    Nobre, E.P.6
  • 104
    • 0025756108 scopus 로고
    • Diazepam withdrawal responses measured in the social interaction test of anxiety and their reversal by baclofen
    • File SE, Mabbutt PS, Andrews N. 1991. Diazepam withdrawal responses measured in the social interaction test of anxiety and their reversal by baclofen. Psychopharmacology 104:62-66.
    • (1991) Psychopharmacology , vol.104 , pp. 62-66
    • File, S.E.1    Mabbutt, P.S.2    Andrews, N.3
  • 105
    • 0026543534 scopus 로고
    • Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal
    • File SE, Zharkovsky A, Hitchcott PK. 1992. Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. Prog Neuropsychopharmacol Biol Psychiatry 16:87-93.
    • (1992) Prog Neuropsychopharmacol Biol Psychiatry , vol.16 , pp. 87-93
    • File, S.E.1    Zharkovsky, A.2    Hitchcott, P.K.3
  • 107
    • 0037010157 scopus 로고    scopus 로고
    • Genetic effects on an animal model of anxiety
    • Flint J. 2002. Genetic effects on an animal model of anxiety. FEBS Lett 529:131-134.
    • (2002) FEBS Lett , vol.529 , pp. 131-134
    • Flint, J.1
  • 108
    • 0037327678 scopus 로고    scopus 로고
    • Animal models of anxiety and their molecular dissection
    • Flint J. 2003. Animal models of anxiety and their molecular dissection. Semin Cell Dev Biol 14:37-42.
    • (2003) Semin Cell Dev Biol , vol.14 , pp. 37-42
    • Flint, J.1
  • 109
    • 0026557515 scopus 로고
    • Antidepressant and anxiolytic effects of alprazolam versus the conventional antidepressant desipramine and the anxiolytic diazepam in the forced swim test in rats
    • Flugy A, Gagliano M, Cannizzaro C, Novara V, Cannizzaro G. 1992. Antidepressant and anxiolytic effects of alprazolam versus the conventional antidepressant desipramine and the anxiolytic diazepam in the forced swim test in rats. Eur J Pharmacol 214: 233-238.
    • (1992) Eur J Pharmacol , vol.214 , pp. 233-238
    • Flugy, A.1    Gagliano, M.2    Cannizzaro, C.3    Novara, V.4    Cannizzaro, G.5
  • 111
    • 0030663872 scopus 로고    scopus 로고
    • Advantages and limitations of the concept of antidepressant therapy
    • Freeman HL. 1997. Advantages and limitations of the concept of antidepressant therapy. Eur Neuropsychopharmacol 7(Suppl 3): S315-S321.
    • (1997) Eur Neuropsychopharmacol , vol.7 , Issue.SUPPL. 3
    • Freeman, H.L.1
  • 112
    • 0036176898 scopus 로고    scopus 로고
    • The comorbidity of bipolar and anxiety disorders: Prevalence, psychobiology, and treatment issues
    • Freeman MP, Freeman SA, McElroy SL. 2002. The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issues. J Affect Disord 68:1-23.
    • (2002) J Affect Disord , vol.68 , pp. 1-23
    • Freeman, M.P.1    Freeman, S.A.2    McElroy, S.L.3
  • 115
    • 0002577727 scopus 로고
    • Animal models of psychiatric disorders
    • Bloom FE, Kupfer DJ, editors, New York: Raven Press, p
    • Geyer MA, Markou A. 1995. Animal models of psychiatric disorders. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: the fourth generation of progress. New York: Raven Press, p 787-798.
    • (1995) Psychopharmacology: The fourth generation of progress , pp. 787-798
    • Geyer, M.A.1    Markou, A.2
  • 117
    • 19344366338 scopus 로고    scopus 로고
    • Quantitative trait loci for novelty/stress- induced locomotor activation in recombinant inbred (RI) and recombinant congenic (RC) strains of mice
    • Gill KJ, Boyle AE. 2005. Quantitative trait loci for novelty/stress- induced locomotor activation in recombinant inbred (RI) and recombinant congenic (RC) strains of mice. Behav Brain Res 161: 113-124.
    • (2005) Behav Brain Res , vol.161 , pp. 113-124
    • Gill, K.J.1    Boyle, A.E.2
  • 118
    • 1542514854 scopus 로고    scopus 로고
    • Do the genetic or environmental determinants of anxiety and depression change with age? A longitudinal study of Australian twins
    • Gillespie NA, Kirk KM, Evans DM, Heath AC, Hickie IB, Martin NG. 2004. Do the genetic or environmental determinants of anxiety and depression change with age? A longitudinal study of Australian twins. Twin Res 7:39-53.
    • (2004) Twin Res , vol.7 , pp. 39-53
    • Gillespie, N.A.1    Kirk, K.M.2    Evans, D.M.3    Heath, A.C.4    Hickie, I.B.5    Martin, N.G.6
  • 119
    • 0034760197 scopus 로고    scopus 로고
    • Anticonvulsants in the treatment of mood disorders: Assessing current and future roles
    • Gilmer WS. 2001. Anticonvulsants in the treatment of mood disorders: assessing current and future roles. Expert Opin Pharmacother 2:1597-1608.
    • (2001) Expert Opin Pharmacother , vol.2 , pp. 1597-1608
    • Gilmer, W.S.1
  • 121
    • 0346665818 scopus 로고    scopus 로고
    • Lower in vivo brain extracellular GABA concentration in diabetic rats during forced swimming
    • Gomez R, Vargas CR, Wajner M, Barros HM. 2003. Lower in vivo brain extracellular GABA concentration in diabetic rats during forced swimming. Brain Res 968:281-284.
    • (2003) Brain Res , vol.968 , pp. 281-284
    • Gomez, R.1    Vargas, C.R.2    Wajner, M.3    Barros, H.M.4
  • 122
    • 0033799811 scopus 로고    scopus 로고
    • Anxiety in healthy humans is associated with orbital frontal chemistry
    • Grachev ID, Apkarian AV 2000. Anxiety in healthy humans is associated with orbital frontal chemistry. Mol Psychiatry 5: 482-488.
    • (2000) Mol Psychiatry , vol.5 , pp. 482-488
    • Grachev, I.D.1    Apkarian, A.V.2
  • 123
    • 0022596779 scopus 로고
    • Modulation of the brain aversive system by GABAergic and serotonergic mechanisms
    • Graeff FG, Brandao ML, Audi EA, Schutz MT. 1986. Modulation of the brain aversive system by GABAergic and serotonergic mechanisms. Behav Brain Res 21:65-72.
    • (1986) Behav Brain Res , vol.21 , pp. 65-72
    • Graeff, F.G.1    Brandao, M.L.2    Audi, E.A.3    Schutz, M.T.4
  • 125
    • 0025719315 scopus 로고
    • Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior
    • Guidotti A. 1991. Role of DBI in brain and its posttranslational processing products in normal and abnormal behavior. Neuropharmacology 30:1425-1433.
    • (1991) Neuropharmacology , vol.30 , pp. 1425-1433
    • Guidotti, A.1
  • 127
    • 0035663937 scopus 로고    scopus 로고
    • The socially-isolated mouse: A model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders
    • Guidotti A, Dong E, Matsumoto K, Pinna G, Rasmusson AM, Costa E. 2001. The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders. Brain Res Rev 37:110-115.
    • (2001) Brain Res Rev , vol.37 , pp. 110-115
    • Guidotti, A.1    Dong, E.2    Matsumoto, K.3    Pinna, G.4    Rasmusson, A.M.5    Costa, E.6
  • 128
    • 0035839259 scopus 로고    scopus 로고
    • Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female rat
    • Gulinello M, Gong QH, Li X, Smith SS. 2001. Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female rat. Brain Res 910:55-66.
    • (2001) Brain Res , vol.910 , pp. 55-66
    • Gulinello, M.1    Gong, Q.H.2    Li, X.3    Smith, S.S.4
  • 129
    • 2642518910 scopus 로고    scopus 로고
    • Toxic cocaine- and convulsant-induced modification of forced swimming behaviors and their interaction with ethanol: Comparison with immobilization stress
    • Hayase T, Yamamoto Y, Yamamoto K. 2002. Toxic cocaine- and convulsant-induced modification of forced swimming behaviors and their interaction with ethanol: comparison with immobilization stress. BMC Pharmacol 2:19.
    • (2002) BMC Pharmacol , vol.2 , pp. 19
    • Hayase, T.1    Yamamoto, Y.2    Yamamoto, K.3
  • 131
    • 12244267112 scopus 로고    scopus 로고
    • Norepinephrine-gamma-aminobutyric acid (GABA) interaction in limbic stress circuits: Effects of reboxetine on GABAergic neurons
    • Herman JP, Renda A, Bodie B. 2003. Norepinephrine-gamma-aminobutyric acid (GABA) interaction in limbic stress circuits: effects of reboxetine on GABAergic neurons. Biol Psychiatry 53:166-174.
    • (2003) Biol Psychiatry , vol.53 , pp. 166-174
    • Herman, J.P.1    Renda, A.2    Bodie, B.3
  • 133
    • 0023918528 scopus 로고
    • Neonatal treatment with monoamine uptake inhibitors alters later response in behavioral 'despair' test to beta and GABA-B receptor agonists
    • Hilakivi LA, Taira T, Hilakivi I, Loikas P. 1988. Neonatal treatment with monoamine uptake inhibitors alters later response in behavioral 'despair' test to beta and GABA-B receptor agonists. Pharmacol Toxicol 63:57-61.
    • (1988) Pharmacol Toxicol , vol.63 , pp. 57-61
    • Hilakivi, L.A.1    Taira, T.2    Hilakivi, I.3    Loikas, P.4
  • 134
    • 0025119972 scopus 로고
    • The supraspinal anxiolytic effect of baclofen for spasticity reduction
    • Hinderer SR. 1990. The supraspinal anxiolytic effect of baclofen for spasticity reduction. Am J Phys Med Rehabil 69:254-258.
    • (1990) Am J Phys Med Rehabil , vol.69 , pp. 254-258
    • Hinderer, S.R.1
  • 135
    • 0036945683 scopus 로고    scopus 로고
    • Behavioral action of ethanol in Porsolt's forced swim test: Modulation by 3 alpha-hydroxy-5 alpha-pregnan-20- one
    • Hirani K, Khisti RT, Chopde CT 2002. Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20- one. Neuropharmacology 43:1339-1350.
    • (2002) Neuropharmacology , vol.43 , pp. 1339-1350
    • Hirani, K.1    Khisti, R.T.2    Chopde, C.T.3
  • 136
    • 21344474109 scopus 로고    scopus 로고
    • Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats
    • Hirani K, Sharma AN, Jain NS, Ugale RR, Chopde CT 2005. Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats. Psychopharmacology 180: 267-278.
    • (2005) Psychopharmacology , vol.180 , pp. 267-278
    • Hirani, K.1    Sharma, A.N.2    Jain, N.S.3    Ugale, R.R.4    Chopde, C.T.5
  • 138
    • 0037126172 scopus 로고    scopus 로고
    • Individual response profiles of male Wistar rats in animal models for anxiety and depression
    • Ho YJ, Eichendorff J, Schwaning RK. 2002. Individual response profiles of male Wistar rats in animal models for anxiety and depression. Behav Brain Res 136:1-12.
    • (2002) Behav Brain Res , vol.136 , pp. 1-12
    • Ho, Y.J.1    Eichendorff, J.2    Schwaning, R.K.3
  • 140
    • 0028213016 scopus 로고
    • Psychological and emotional effects of the use of oral baclofen: A preliminary study
    • Jamous A, Kennedy P, Psychol C, Grey N. 1994. Psychological and emotional effects of the use of oral baclofen: a preliminary study. Paraplegia 32:349-353.
    • (1994) Paraplegia , vol.32 , pp. 349-353
    • Jamous, A.1    Kennedy, P.2    Psychol, C.3    Grey, N.4
  • 141
    • 0034879062 scopus 로고    scopus 로고
    • GABAergic and glutamatergic modulation of exploratory behavior in the dorsomedial hypothalamus
    • Jardim MC, Guimaraes FS. 2001. GABAergic and glutamatergic modulation of exploratory behavior in the dorsomedial hypothalamus. Pharmacol Biochem Behav 69:579-584.
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 579-584
    • Jardim, M.C.1    Guimaraes, F.S.2
  • 142
    • 0035976597 scopus 로고    scopus 로고
    • Activation of GABA(A) receptors in the amygdala blocks the acquisition and expression of conditioned defeat in Syrian hamsters
    • Jasnow AM, Huhman KL. 2001. Activation of GABA(A) receptors in the amygdala blocks the acquisition and expression of conditioned defeat in Syrian hamsters. Brain Res 920:142-150.
    • (2001) Brain Res , vol.920 , pp. 142-150
    • Jasnow, A.M.1    Huhman, K.L.2
  • 143
    • 0034049958 scopus 로고    scopus 로고
    • The antidepressive-like effect of oxcarbazepine: Possible role of dopaminergic neurotransmission
    • Joca SR, Skalisz LL, Beijamini V, Vital MA, Andreatini R. 2000. The antidepressive-like effect of oxcarbazepine: possible role of dopaminergic neurotransmission. Eur Neuropsychopharmacol 10: 223-238.
    • (2000) Eur Neuropsychopharmacol , vol.10 , pp. 223-238
    • Joca, S.R.1    Skalisz, L.L.2    Beijamini, V.3    Vital, M.A.4    Andreatini, R.5
  • 146
    • 0346542468 scopus 로고    scopus 로고
    • New problems in GABAergic pharmacology of anxiety
    • Kalueff AV 1997. New problems in GABAergic pharmacology of anxiety. Eksp Klin Farmakol 60:3-7.
    • (1997) Eksp Klin Farmakol , vol.60 , pp. 3-7
    • Kalueff, A.V.1
  • 147
    • 0030439842 scopus 로고    scopus 로고
    • Role of GABA in memory and anxiety
    • Kalueff A, Nutt DJ. 1996. Role of GABA in memory and anxiety. Depress Anxiety 4:100-110.
    • (1996) Depress Anxiety , vol.4 , pp. 100-110
    • Kalueff, A.1    Nutt, D.J.2
  • 148
    • 0016600908 scopus 로고
    • Effects of antidepressant drugs on amygdaloid after-discharge in rats
    • Kamei C, Masuda Y, Oka M, Shimizu M. 1975. Effects of antidepressant drugs on amygdaloid after-discharge in rats. Jpn J Pharmacol 25:359-365.
    • (1975) Jpn J Pharmacol , vol.25 , pp. 359-365
    • Kamei, C.1    Masuda, Y.2    Oka, M.3    Shimizu, M.4
  • 149
    • 0028886176 scopus 로고
    • Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECT
    • Kaschka W, Feistel H, Ebert D. 1995. Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECT. J Psychiatr Res 29:427-434.
    • (1995) J Psychiatr Res , vol.29 , pp. 427-434
    • Kaschka, W.1    Feistel, H.2    Ebert, D.3
  • 150
    • 0033574022 scopus 로고    scopus 로고
    • Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase
    • Kash SF, Tecott LH, Hodge C, Baekkeskov S. 1999. Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci USA 96:1698-1703.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1698-1703
    • Kash, S.F.1    Tecott, L.H.2    Hodge, C.3    Baekkeskov, S.4
  • 151
    • 0037099308 scopus 로고    scopus 로고
    • Psychological stress, but not physical stress, causes increase in diazepam binding inhibitor (DBI) mRNA expression in mouse brains
    • Katsura M, Mohri Y, Shuto K, Tsujimura A, Ukai M, Ohkuma S. 2002. Psychological stress, but not physical stress, causes increase in diazepam binding inhibitor (DBI) mRNA expression in mouse brains. Mol Brain Res 104:103-109.
    • (2002) Mol Brain Res , vol.104 , pp. 103-109
    • Katsura, M.1    Mohri, Y.2    Shuto, K.3    Tsujimura, A.4    Ukai, M.5    Ohkuma, S.6
  • 152
    • 0032464043 scopus 로고    scopus 로고
    • Adjunctive tiagabine treatment of psychiatric disorders: Three cases
    • Kaufmann KR. 1998. Adjunctive tiagabine treatment of psychiatric disorders: three cases. Ann Clin Psychiatry 10:181-184.
    • (1998) Ann Clin Psychiatry , vol.10 , pp. 181-184
    • Kaufmann, K.R.1
  • 153
    • 0030770172 scopus 로고    scopus 로고
    • The olfactory bulbectomized rat as a model of depression: An update
    • Kelly JP, Wrynn AS, Leonard BE. 1997. The olfactory bulbectomized rat as a model of depression: an update. Pharmacol Ther 74: 299-316.
    • (1997) Pharmacol Ther , vol.74 , pp. 299-316
    • Kelly, J.P.1    Wrynn, A.S.2    Leonard, B.E.3
  • 154
    • 0022454306 scopus 로고
    • Symptoms of anxiety and depression in a volunteer twin population. The etiologic role of genetic and environmental factors
    • Kendler KS, Heath A, Martin NG, Eaves LJ. 1986. Symptoms of anxiety and depression in a volunteer twin population. The etiologic role of genetic and environmental factors. Arch Gen Psychiatry 43:213-221.
    • (1986) Arch Gen Psychiatry , vol.43 , pp. 213-221
    • Kendler, K.S.1    Heath, A.2    Martin, N.G.3    Eaves, L.J.4
  • 155
    • 0023240012 scopus 로고
    • Symptoms of anxiety and symptoms of depression. Same genes, different environments?
    • Kendler KS, Heath AC, Martin NG, Eaves LJ. 1987. Symptoms of anxiety and symptoms of depression. Same genes, different environments? Arch Gen Psychiatry 44:451-457.
    • (1987) Arch Gen Psychiatry , vol.44 , pp. 451-457
    • Kendler, K.S.1    Heath, A.C.2    Martin, N.G.3    Eaves, L.J.4
  • 156
    • 23944493552 scopus 로고    scopus 로고
    • Subtype-specific GABA transporter antagonists synergetically modulate phasic and tonic GABAA conductance in rat neocortex
    • Keros S, Hablitz JJ. 2005. Subtype-specific GABA transporter antagonists synergetically modulate phasic and tonic GABAA conductance in rat neocortex. J Neurophysiol 94: 2073-2085.
    • (2005) J Neurophysiol , vol.94 , pp. 2073-2085
    • Keros, S.1    Hablitz, J.J.2
  • 157
    • 0036125705 scopus 로고    scopus 로고
    • Predictors of treatment response in bipolar disorders: Evidence from clinical and brain imaging studies
    • Ketter TA, Wang PW 2002. Predictors of treatment response in bipolar disorders: evidence from clinical and brain imaging studies. J Clin Psychiatry 63(Suppl 3):21-25.
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 3 , pp. 21-25
    • Ketter, T.A.1    Wang, P.W.2
  • 158
    • 0033672097 scopus 로고    scopus 로고
    • Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test
    • Khisti RT, Chopde CT, Jain SP. 2000. Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test. Pharmacol Biochem Behav 67:137-143.
    • (2000) Pharmacol Biochem Behav , vol.67 , pp. 137-143
    • Khisti, R.T.1    Chopde, C.T.2    Jain, S.P.3
  • 160
    • 1842453029 scopus 로고    scopus 로고
    • Activation of the amygdala and anterior cingulate during nonconscious processing of sad versus happy faces
    • Killgore WD, Yurgelun-Todd DA. 2004. Activation of the amygdala and anterior cingulate during nonconscious processing of sad versus happy faces. Neuroimage 21:1215-1223.
    • (2004) Neuroimage , vol.21 , pp. 1215-1223
    • Killgore, W.D.1    Yurgelun-Todd, D.A.2
  • 161
    • 29144468592 scopus 로고    scopus 로고
    • Social anxiety predicts amygdala activation in adolescents viewing fearful faces
    • Killgore WD, Yurgelun-Todd DA. 2005. Social anxiety predicts amygdala activation in adolescents viewing fearful faces. Neuroreport 16:1671-1675.
    • (2005) Neuroreport , vol.16 , pp. 1671-1675
    • Killgore, W.D.1    Yurgelun-Todd, D.A.2
  • 162
    • 28444445585 scopus 로고    scopus 로고
    • GABAa receptor subtypes as targets for neuropsychiatrie drug development
    • Korpi ER, Sinkkonen ST. 2006. GABAa receptor subtypes as targets for neuropsychiatrie drug development. Pharmacol Ther 109: 12-32.
    • (2006) Pharmacol Ther , vol.109 , pp. 12-32
    • Korpi, E.R.1    Sinkkonen, S.T.2
  • 163
  • 164
    • 0842304913 scopus 로고    scopus 로고
    • Diminished GABAa receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety
    • Kosel M, Rudolph U, Wielepp P, Luginbuhl M, Schmitt W, Fisch HU, Schlaeper TE. 2004. Diminished GABAa receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety. Neuropsychopharmacology 29: 347-350.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 347-350
    • Kosel, M.1    Rudolph, U.2    Wielepp, P.3    Luginbuhl, M.4    Schmitt, W.5    Fisch, H.U.6    Schlaeper, T.E.7
  • 166
    • 29744451802 scopus 로고    scopus 로고
    • Modeling depression: Social dominance-submission gene expression patterns in rat neocortex
    • Kroes RA, Panksepp J, Burgdorf J, Otto NJ, Moskal JR. 2005. Modeling depression: social dominance-submission gene expression patterns in rat neocortex. Neuroscience 137:37-49.
    • (2005) Neuroscience , vol.137 , pp. 37-49
    • Kroes, R.A.1    Panksepp, J.2    Burgdorf, J.3    Otto, N.J.4    Moskal, J.R.5
  • 170
    • 0038802624 scopus 로고    scopus 로고
    • Experimental anxiety and antiepileptics: The effects of valproate and vigabatrin in the mirrored chamber test
    • Lang AP, de Angelis L. 2003. Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test. Methods Find Exp Clin Pharmacol 25:265-271.
    • (2003) Methods Find Exp Clin Pharmacol , vol.25 , pp. 265-271
    • Lang, A.P.1    de Angelis, L.2
  • 171
    • 0035727708 scopus 로고    scopus 로고
    • Phenibut (beta-phenyl-GABA): A tranquilizer and nootropic drug
    • Lapin I. 2001. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev 7:471-481.
    • (2001) CNS Drug Rev , vol.7 , pp. 471-481
    • Lapin, I.1
  • 173
    • 0025938589 scopus 로고
    • Compared efficacy of prazepam and clomipramine in major depression with anxiety: A multicenter controlled study
    • Lemoine P, Boulenger JP, Caillard V, Tanne N, Bonnet D. 1991. Compared efficacy of prazepam and clomipramine in major depression with anxiety: a multicenter controlled study. Pharmacopsychiatry 24:175-179.
    • (1991) Pharmacopsychiatry , vol.24 , pp. 175-179
    • Lemoine, P.1    Boulenger, J.P.2    Caillard, V.3    Tanne, N.4    Bonnet, D.5
  • 174
    • 1542395814 scopus 로고    scopus 로고
    • GABAergic functions and depression: From classical therapies to herbal medicine
    • Leung JW, Xue H. 2003. GABAergic functions and depression: from classical therapies to herbal medicine. Curr Drug Targets CNS Neurol Disord 2:363-374.
    • (2003) Curr Drug Targets CNS Neurol Disord , vol.2 , pp. 363-374
    • Leung, J.W.1    Xue, H.2
  • 176
    • 0036920850 scopus 로고    scopus 로고
    • Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropin-releasing hormone receptor-dependent mechanism
    • Linthorst AC, Penalva RG, Flachskamrn C, Holsboer F, Reul JM. 2002. Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropin-releasing hormone receptor-dependent mechanism. Eur J Neurosci 16: 2441-2452.
    • (2002) Eur J Neurosci , vol.16 , pp. 2441-2452
    • Linthorst, A.C.1    Penalva, R.G.2    Flachskamrn, C.3    Holsboer, F.4    Reul, J.M.5
  • 178
    • 0021933150 scopus 로고
    • Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: A common action of repeated administration of different classes of antidepressants and electroshock
    • Lloyd KG, Thuret F, Pile A. 1985. Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock. J Pharmacol Exp Ther 235: 191-199.
    • (1985) J Pharmacol Exp Ther , vol.235 , pp. 191-199
    • Lloyd, K.G.1    Thuret, F.2    Pile, A.3
  • 179
    • 0023183541 scopus 로고
    • Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile
    • Lloyd KG, Zivkovic B, Sanger D, Depoortere H, Bartholini G. 1987. Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. J Pharmacol Exp Ther 241:245-250.
    • (1987) J Pharmacol Exp Ther , vol.241 , pp. 245-250
    • Lloyd, K.G.1    Zivkovic, B.2    Sanger, D.3    Depoortere, H.4    Bartholini, G.5
  • 181
    • 0345515983 scopus 로고    scopus 로고
    • Cholecystokinin in CSF from depressed patients: Possible relations to severity of depression and suicidal behavior
    • Lofberg C, Agren H, Harro J, Oreland L. 1998. Cholecystokinin in CSF from depressed patients: possible relations to severity of depression and suicidal behavior. Eur Neuropsychopharmacol 8: 153-157.
    • (1998) Eur Neuropsychopharmacol , vol.8 , pp. 153-157
    • Lofberg, C.1    Agren, H.2    Harro, J.3    Oreland, L.4
  • 184
    • 0037237412 scopus 로고    scopus 로고
    • The role of GABA in anxiety disorders
    • Lydiard RB. 2003. The role of GABA in anxiety disorders. J Clin Psychiatry 64(Suppl 3):21-27.
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 3 , pp. 21-27
    • Lydiard, R.B.1
  • 185
    • 27544506908 scopus 로고    scopus 로고
    • Effects of repetitive transcranial magnetic stimulation in depression: A magnetoencephalographic study
    • Maihofner C, Ropohl A, Reulbach U, Hiller M, Elstner S, Kornhuber J, Sperling W 2005. Effects of repetitive transcranial magnetic stimulation in depression: a magnetoencephalographic study. Neuroreport 16:1839-1842.
    • (2005) Neuroreport , vol.16 , pp. 1839-1842
    • Maihofner, C.1    Ropohl, A.2    Reulbach, U.3    Hiller, M.4    Elstner, S.5    Kornhuber, J.6    Sperling, W.7
  • 186
    • 0028905543 scopus 로고
    • Effects of amitriptyline on GABA-stimulated 36CI-uptake in relation to a behavioral model of depression
    • Malatynska E, De Leon I, Allen D, Yamamura HI. 1995. Effects of amitriptyline on GABA-stimulated 36CI-uptake in relation to a behavioral model of depression. Brain Res Bull 37:53-59.
    • (1995) Brain Res Bull , vol.37 , pp. 53-59
    • Malatynska, E.1    De Leon, I.2    Allen, D.3    Yamamura, H.I.4
  • 187
    • 0034733905 scopus 로고    scopus 로고
    • Antidepressant effects on GABA-stimulated 36Cl(-) influx in rat cerebral cortex are altered after treatment with GABA(A) receptor antisense oligodeoxynucleotides
    • Malatynska E, Crites GJ, Harrawood D, Goldenberg R, Matheson GK. 2000. Antidepressant effects on GABA-stimulated 36Cl(-) influx in rat cerebral cortex are altered after treatment with GABA(A) receptor antisense oligodeoxynucleotides. Brain Res 869:78-84.
    • (2000) Brain Res , vol.869 , pp. 78-84
    • Malatynska, E.1    Crites, G.J.2    Harrawood, D.3    Goldenberg, R.4    Matheson, G.K.5
  • 189
    • 0031902127 scopus 로고    scopus 로고
    • Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: Preliminary results from a quantitative PET study
    • Malizia AL, Cunningham VJ, Bell CJ, Liddle PF, Jones T, Nutt DJ. 1998. Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study. Arch Gen Psychiatry 55:715-720.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 715-720
    • Malizia, A.L.1    Cunningham, V.J.2    Bell, C.J.3    Liddle, P.F.4    Jones, T.5    Nutt, D.J.6
  • 190
    • 4544221777 scopus 로고    scopus 로고
    • Functional mapping of GABAA receptor subtypes in the amygdala
    • Marowsky A, Fritschy JM, Vogl KE. 2004. Functional mapping of GABAA receptor subtypes in the amygdala. Eur J Neurosci 20: 1281-1289.
    • (2004) Eur J Neurosci , vol.20 , pp. 1281-1289
    • Marowsky, A.1    Fritschy, J.M.2    Vogl, K.E.3
  • 191
    • 0035980626 scopus 로고    scopus 로고
    • Human GABAbR genomic structure: Evidence for splice variants in GABAbR1 but not GABAbR2
    • Martin SC, Russek SJ, Farb DH. 2001. Human GABAbR genomic structure: evidence for splice variants in GABAbR1 but not GABAbR2. Gene 278:63-79.
    • (2001) Gene , vol.278 , pp. 63-79
    • Martin, S.C.1    Russek, S.J.2    Farb, D.H.3
  • 194
    • 9644310533 scopus 로고    scopus 로고
    • Neurosteroids and sigma1 receptors, biochemical and behavioral relevance
    • Maurice T. 2004. Neurosteroids and sigma1 receptors, biochemical and behavioral relevance. Pharmacopsychiatry 37(Suppl 3): S171-S182.
    • (2004) Pharmacopsychiatry , vol.37 , Issue.SUPPL. 3
    • Maurice, T.1
  • 195
    • 0035227354 scopus 로고    scopus 로고
    • Overview of the past contributions in animal models and their changing place in psychiatry
    • McKinney WT. 2004. Overview of the past contributions in animal models and their changing place in psychiatry. Semin Clin Psychiatry 6:68-78.
    • (2004) Semin Clin Psychiatry , vol.6 , pp. 68-78
    • McKinney, W.T.1
  • 196
    • 0020607619 scopus 로고
    • Benzodiazepine receptors in rat cerebelar cortex and hippocampus undergo rapid and reversible changes after acute stress
    • Medina JH, Novas ML, Wolfman CN, Levi de Stein M, De Robertis E. 1983. Benzodiazepine receptors in rat cerebelar cortex and hippocampus undergo rapid and reversible changes after acute stress. Neuroscience 9:331-335.
    • (1983) Neuroscience , vol.9 , pp. 331-335
    • Medina, J.H.1    Novas, M.L.2    Wolfman, C.N.3    Levi de Stein, M.4    De Robertis, E.5
  • 197
    • 24044510481 scopus 로고    scopus 로고
    • Distinct gene expression profiles in hippocampus and amygdala after fear conditioning
    • Mei B, Li C, Dong S, Jiang CH, Wang H, Hu Y. 2005. Distinct gene expression profiles in hippocampus and amygdala after fear conditioning. Brain Res Bull 67:1-12.
    • (2005) Brain Res Bull , vol.67 , pp. 1-12
    • Mei, B.1    Li, C.2    Dong, S.3    Jiang, C.H.4    Wang, H.5    Hu, Y.6
  • 199
    • 0142030651 scopus 로고    scopus 로고
    • Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression
    • Michael N, Erfurth A, Ohrmann P, Arolt V, Heindel W, Pfleiderer B. 2003. Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression. Psychol Med 33: 1277-1284.
    • (2003) Psychol Med , vol.33 , pp. 1277-1284
    • Michael, N.1    Erfurth, A.2    Ohrmann, P.3    Arolt, V.4    Heindel, W.5    Pfleiderer, B.6
  • 201
    • 0022821365 scopus 로고
    • Regional cerebral glucose metabolism in anxiety disorders studied with positron emission tomography before and after psychosurgical intervention. A preliminary report
    • Mindus P, Ericson K, Greitz T, Meyerson BA, Nyman H, Sjogren I. 1986. Regional cerebral glucose metabolism in anxiety disorders studied with positron emission tomography before and after psychosurgical intervention. A preliminary report. Acta Radiol Suppl 369:444-448.
    • (1986) Acta Radiol , Issue.SUPPL. 369 , pp. 444-448
    • Mindus, P.1    Ericson, K.2    Greitz, T.3    Meyerson, B.A.4    Nyman, H.5    Sjogren, I.6
  • 202
    • 36048957020 scopus 로고    scopus 로고
    • MGI, Jackson Laboratory, Bar Harbor, ME
    • MGI. 2006. Mouse Genome Informatics, http://www.informatics.jax.org/ Jackson Laboratory, Bar Harbor, ME.
    • (2006)
  • 204
    • 2442682706 scopus 로고    scopus 로고
    • Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior
    • Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JE 2004. Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacology 29: 1050-1062.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1050-1062
    • Mombereau, C.1    Kaupmann, K.2    Froestl, W.3    Sansig, G.4    van der Putten, H.5    Cryan, J.E.6
  • 206
    • 0027215810 scopus 로고
    • Repeated swim-stress reduces GABAA receptor alpha subunit mRNAs in the mouse hippocampus
    • Montpied P, Weizman A, Weizman R, Kook KA, Morrow AL, Paul SM. 1993. Repeated swim-stress reduces GABAA receptor alpha subunit mRNAs in the mouse hippocampus. Mol Brain Res 18: 267-272.
    • (1993) Mol Brain Res , vol.18 , pp. 267-272
    • Montpied, P.1    Weizman, A.2    Weizman, R.3    Kook, K.A.4    Morrow, A.L.5    Paul, S.M.6
  • 208
    • 0029670943 scopus 로고    scopus 로고
    • Involvement of GABA(B) receptor systems in action of antidepressants: Baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats
    • Nakagawa Y, Ishima T, Ishibashi Y, Yoshii T, Takashima T 1996a. Involvement of GABA(B) receptor systems in action of antidepressants: baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats. Brain Res 709: 215-220.
    • (1996) Brain Res , vol.709 , pp. 215-220
    • Nakagawa, Y.1    Ishima, T.2    Ishibashi, Y.3    Yoshii, T.4    Takashima, T.5
  • 209
    • 0030601918 scopus 로고    scopus 로고
    • Involvement of GABA(B) receptor systems in action of antidepressants: Baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats
    • Nakagawa Y, Ishima T, Ishibashi Y, Yoshii T, Takashima T 1996b. Involvement of GABA(B) receptor systems in action of antidepressants: baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats. Brain Res 741: 240-245.
    • (1996) Brain Res , vol.741 , pp. 240-245
    • Nakagawa, Y.1    Ishima, T.2    Ishibashi, Y.3    Yoshii, T.4    Takashima, T.5
  • 210
    • 0014440086 scopus 로고
    • Sensations evoked by stimulation in the midbrain of man
    • Nashold BC, Wilson WP, Slaughter DG. 1969. Sensations evoked by stimulation in the midbrain of man. J Neurosurg 30:14-24.
    • (1969) J Neurosurg , vol.30 , pp. 14-24
    • Nashold, B.C.1    Wilson, W.P.2    Slaughter, D.G.3
  • 211
    • 4644336231 scopus 로고    scopus 로고
    • The role of GABA in the pathophysiology and treatment of anxiety disorders
    • Nemeroff CB. 2003. The role of GABA in the pathophysiology and treatment of anxiety disorders. Psychopharmacol Bull 37: 133-146.
    • (2003) Psychopharmacol Bull , vol.37 , pp. 133-146
    • Nemeroff, C.B.1
  • 214
    • 0026549330 scopus 로고
    • Effects of alprazolam on anxiety-related behavior of rats in a modified forced-swim test employing straw suspension
    • Nishimura H, Tanaka M. 1992. Effects of alprazolam on anxiety-related behavior of rats in a modified forced-swim test employing straw suspension. Pharmacol Biochem Behav 41:425-427.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 425-427
    • Nishimura, H.1    Tanaka, M.2
  • 215
    • 0024341406 scopus 로고
    • Opposite effects of diazepam and beta-CCE on immobility and straw-climbing behavior of rats in a modified forced-swim test
    • Nishimura H, Ida Y, Tsuda A, Tanaka M. 1989. Opposite effects of diazepam and beta-CCE on immobility and straw-climbing behavior of rats in a modified forced-swim test. Pharmacol Biochem Behav 33:227-231.
    • (1989) Pharmacol Biochem Behav , vol.33 , pp. 227-231
    • Nishimura, H.1    Ida, Y.2    Tsuda, A.3    Tanaka, M.4
  • 216
    • 0344255594 scopus 로고    scopus 로고
    • Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: Effects of muscimol and midazolam
    • Nobre MJ, Brandao ML. 2004. Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: effects of muscimol and midazolam. Eur Neuropsychophannacol 14: 45-52.
    • (2004) Eur Neuropsychophannacol , vol.14 , pp. 45-52
    • Nobre, M.J.1    Brandao, M.L.2
  • 217
    • 0033652216 scopus 로고    scopus 로고
    • Treatment of depression and concomitant anxiety
    • Nutt D. 2000. Treatment of depression and concomitant anxiety. Eur Neuropsychophannacol 10(Suppl 4):S433-S437.
    • (2000) Eur Neuropsychophannacol , vol.10 , Issue.SUPPL. 4
    • Nutt, D.1
  • 218
    • 0034966077 scopus 로고    scopus 로고
    • Neurobiological mechanisms in generalized anxiety disorder
    • Nutt DJ. 2001. Neurobiological mechanisms in generalized anxiety disorder. J Clin Psychiatry 62(Suppl 11):22-27.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 11 , pp. 22-27
    • Nutt, D.J.1
  • 219
    • 12344310143 scopus 로고    scopus 로고
    • Overview of diagnosis and drug treatments of anxiety disorders
    • Nutt DJ. 2005. Overview of diagnosis and drug treatments of anxiety disorders. CNS Spectrums 10:49-56.
    • (2005) CNS Spectrums , vol.10 , pp. 49-56
    • Nutt, D.J.1
  • 220
    • 0035186421 scopus 로고    scopus 로고
    • New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder
    • Nutt DJ, Malizia AL. 2001. New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder. Br J Psychiatry 179:390-396.
    • (2001) Br J Psychiatry , vol.179 , pp. 390-396
    • Nutt, D.J.1    Malizia, A.L.2
  • 223
    • 0022385858 scopus 로고
    • Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolain: Studies on the olfactory bulbectomized rat model of depression
    • O'Connor WT, Earley B, Leonard BE. 1985. Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolain: studies on the olfactory bulbectomized rat model of depression. Br J Clin Pharmacol 19(Suppl 1):49S-56S.
    • (1985) Br J Clin Pharmacol , vol.19 , Issue.SUPPL. 1
    • O'Connor, W.T.1    Earley, B.2    Leonard, B.E.3
  • 224
    • 0029188325 scopus 로고
    • Neuroactive steroid modulation of GABAA receptors
    • Olsen RW, Sapp DM. 1995. Neuroactive steroid modulation of GABAA receptors. Adv Biochem Psychopharmacol 48:57-74.
    • (1995) Adv Biochem Psychopharmacol , vol.48 , pp. 57-74
    • Olsen, R.W.1    Sapp, D.M.2
  • 225
    • 0025812169 scopus 로고
    • Allosteric actions of central nervous system depressants including anesthetics on subtypes of the inhibitory gamma-aminobutyric acid A receptor-chloride channel complex
    • Olsen RW, Sapp DM, Bureau MH, Turner DM, Kokka N. 1991. Allosteric actions of central nervous system depressants including anesthetics on subtypes of the inhibitory gamma-aminobutyric acid A receptor-chloride channel complex. Ann N Y Acad Sci 625: 145-154.
    • (1991) Ann N Y Acad Sci , vol.625 , pp. 145-154
    • Olsen, R.W.1    Sapp, D.M.2    Bureau, M.H.3    Turner, D.M.4    Kokka, N.5
  • 227
    • 30744447976 scopus 로고    scopus 로고
    • Clinical potential of GABA(B) receptor modulators
    • Ong J, Kerr DI. 2005. Clinical potential of GABA(B) receptor modulators. CNS Drug Rev 11:317-334.
    • (2005) CNS Drug Rev , vol.11 , pp. 317-334
    • Ong, J.1    Kerr, D.I.2
  • 229
    • 0021613106 scopus 로고
    • Depression and its treatment in alcoholics: A review
    • O'Sullivan K. 1984. Depression and its treatment in alcoholics: a review. Can J Psychiatry 29:379-384.
    • (1984) Can J Psychiatry , vol.29 , pp. 379-384
    • O'Sullivan, K.1
  • 230
    • 0033976225 scopus 로고    scopus 로고
    • Prior electrical stimulation of the inferior colliculus sensitizes rats to the stress of the elevated plus-maze test
    • Pandossio JE, Molina VA, Brandao ML. 2000. Prior electrical stimulation of the inferior colliculus sensitizes rats to the stress of the elevated plus-maze test. Behav Brain Res 109: 19-25.
    • (2000) Behav Brain Res , vol.109 , pp. 19-25
    • Pandossio, J.E.1    Molina, V.A.2    Brandao, M.L.3
  • 232
    • 0029164246 scopus 로고
    • GABA and mood disorders: A brief review and hypothesis
    • Petty F. 1995. GABA and mood disorders: a brief review and hypothesis. J Affect Disord 34:275-281.
    • (1995) J Affect Disord , vol.34 , pp. 275-281
    • Petty, F.1
  • 233
    • 0019417173 scopus 로고
    • GABAergic modulation of learned helplessness
    • Petty F, Sherman AD. 1981. GABAergic modulation of learned helplessness. Pharmacol Biochem Behav 15:567-570.
    • (1981) Pharmacol Biochem Behav , vol.15 , pp. 567-570
    • Petty, F.1    Sherman, A.D.2
  • 236
    • 0028856465 scopus 로고
    • Benzodiazepines as antidepressants: Does GABA play a role in depression?
    • Petty F, Trivedi MH, Fulton M, Rush AJ. 1995. Benzodiazepines as antidepressants: does GABA play a role in depression? Biol Psychiatry 38:578-591.
    • (1995) Biol Psychiatry , vol.38 , pp. 578-591
    • Petty, F.1    Trivedi, M.H.2    Fulton, M.3    Rush, A.J.4
  • 238
    • 30444441081 scopus 로고    scopus 로고
    • GABAergic hypotheses of anxiety and depression: Focus on GABA(B) receptors
    • Pile A, Nowak G. 2005. GABAergic hypotheses of anxiety and depression: Focus on GABA(B) receptors. Drugs Today 41: 755-766.
    • (2005) Drugs Today , vol.41 , pp. 755-766
    • Pile, A.1    Nowak, G.2
  • 239
    • 17644361932 scopus 로고    scopus 로고
    • Differing psychotropic profiles of anticonvulsants in bipolar and other psychiatric disorders
    • Post RM. 2004. Differing psychotropic profiles of anticonvulsants in bipolar and other psychiatric disorders. Clin Neurosci Res 4: 9-30.
    • (2004) Clin Neurosci Res , vol.4 , pp. 9-30
    • Post, R.M.1
  • 242
    • 0037276640 scopus 로고    scopus 로고
    • Inhibition of the amygdala: Key to pathological states?
    • Quirk GJ, Gehlert DR. 2003. Inhibition of the amygdala: key to pathological states? Ann N Y Acad Sci 985:263-272.
    • (2003) Ann N Y Acad Sci , vol.985 , pp. 263-272
    • Quirk, G.J.1    Gehlert, D.R.2
  • 243
    • 0033662501 scopus 로고    scopus 로고
    • Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation
    • Raghavendra V, Kaur G, Kulkarni SK. 2000. Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation. Eur Neuropsychophannacol 10:473-481.
    • (2000) Eur Neuropsychophannacol , vol.10 , pp. 473-481
    • Raghavendra, V.1    Kaur, G.2    Kulkarni, S.K.3
  • 244
    • 0025192928 scopus 로고
    • Stress-protection action of beta-phenyl(GABA): Involvement of central and peripheral type benzodiazepine binding sites
    • Rago L, Kiivet RA, Adojaan A, Harro J, Allikmets L. 1990. Stress-protection action of beta-phenyl(GABA): involvement of central and peripheral type benzodiazepine binding sites. Pharmacol Toxicol 66:41-44.
    • (1990) Pharmacol Toxicol , vol.66 , pp. 41-44
    • Rago, L.1    Kiivet, R.A.2    Adojaan, A.3    Harro, J.4    Allikmets, L.5
  • 245
    • 0042808739 scopus 로고    scopus 로고
    • Depression: What we can learn from postmortem studies
    • Rajkowska G. 2003. Depression: what we can learn from postmortem studies. Neuroscientist 9:273-284.
    • (2003) Neuroscientist , vol.9 , pp. 273-284
    • Rajkowska, G.1
  • 247
    • 20044396590 scopus 로고    scopus 로고
    • Quality-of-life impainnent in depressive and anxiety disorders
    • Rapaport MH, Clary C, Fayyad R, Endicott J. 2005. Quality-of-life impainnent in depressive and anxiety disorders. Am J Psychiatry 162: 1171-1178.
    • (2005) Am J Psychiatry , vol.162 , pp. 1171-1178
    • Rapaport, M.H.1    Clary, C.2    Fayyad, R.3    Endicott, J.4
  • 249
    • 0037334387 scopus 로고    scopus 로고
    • Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions?
    • Reddy DS. 2003. Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions? Trends Pharmacol Sci 24: 103-106.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 103-106
    • Reddy, D.S.1
  • 250
    • 11144284666 scopus 로고    scopus 로고
    • Anxiolytic activity of progesterone in progesterone receptor knockout mice
    • Reddy DS, O'Malley BW, Rogawski MA. 2005. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology 48:14-24.
    • (2005) Neuropharmacology , vol.48 , pp. 14-24
    • Reddy, D.S.1    O'Malley, B.W.2    Rogawski, M.A.3
  • 252
    • 0032484632 scopus 로고    scopus 로고
    • Evaluation of endozepine-like immunoreactivity in the frontal cortex of suicide victims
    • Rochet T, Tonon MC, Kopp N, Vaudry H, Miachon S. 1998. Evaluation of endozepine-like immunoreactivity in the frontal cortex of suicide victims. Neuroreport 9:53-56.
    • (1998) Neuroreport , vol.9 , pp. 53-56
    • Rochet, T.1    Tonon, M.C.2    Kopp, N.3    Vaudry, H.4    Miachon, S.5
  • 253
    • 0030733915 scopus 로고    scopus 로고
    • Animal models of 'anxiety': Where next?
    • Rodgers RJ. 1997. Animal models of 'anxiety': where next? Behav Pharmacol 8:477-496.
    • (1997) Behav Pharmacol , vol.8 , pp. 477-496
    • Rodgers, R.J.1
  • 254
    • 0001001235 scopus 로고
    • Metrazol tolerance in a normal volunteer population; an investigation of the potential significance of abnormal findings
    • Rodin E. 1958. Metrazol tolerance in a normal volunteer population; an investigation of the potential significance of abnormal findings. EEG Clin Neurophysiol Suppl 10:433-446.
    • (1958) EEG Clin Neurophysiol , Issue.SUPPL. 10 , pp. 433-446
    • Rodin, E.1
  • 255
    • 0014799024 scopus 로고
    • Metrazol tolerance in a "nonnal" volunteer population. A ten year follow-up report
    • Rodin E. 1970. Metrazol tolerance in a "nonnal" volunteer population. A ten year follow-up report. J Nerv Ment Dis 150:438-443.
    • (1970) J Nerv Ment Dis , vol.150 , pp. 438-443
    • Rodin, E.1
  • 256
    • 3142774111 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions
    • Rogawski MA, Loscher W 2004. The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nat Med 10:685-692.
    • (2004) Nat Med , vol.10 , pp. 685-692
    • Rogawski, M.A.1    Loscher, W.2
  • 257
    • 0142026859 scopus 로고    scopus 로고
    • Validation of GABAa receptor subtypes as potential drug targets by using genetically modified mice
    • Rosahl TW. 2003. Validation of GABAa receptor subtypes as potential drug targets by using genetically modified mice. Curr Drug Targets CNS Neurol Disord 2:207-212.
    • (2003) Curr Drug Targets CNS Neurol Disord , vol.2 , pp. 207-212
    • Rosahl, T.W.1
  • 258
    • 4444234860 scopus 로고    scopus 로고
    • Tiagabine for the treatment of generalized anxiety disorder: A randomized, open-label, clinical trial with paroxetine as a positive control
    • Rosenthal M. 2003. Tiagabine for the treatment of generalized anxiety disorder: a randomized, open-label, clinical trial with paroxetine as a positive control. J Clin Psychiatry 64: 1245-1249.
    • (2003) J Clin Psychiatry , vol.64 , pp. 1245-1249
    • Rosenthal, M.1
  • 259
    • 27644535446 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation in treatment-resistant depressed patients: A double-blind, placebo-controlled trial
    • Rossini D, Lucca A, Zanardi R, Magri L, Smcraldi E. 2005. Transcranial magnetic stimulation in treatment-resistant depressed patients: a double-blind, placebo-controlled trial. Psychiatry Res 137: 1-10.
    • (2005) Psychiatry Res , vol.137 , pp. 1-10
    • Rossini, D.1    Lucca, A.2    Zanardi, R.3    Magri, L.4    Smcraldi, E.5
  • 261
    • 0025746648 scopus 로고
    • Cerebrospinal fluid diazepam binding inhibitor in depressed patients and normal controls
    • Roy A. 1991. Cerebrospinal fluid diazepam binding inhibitor in depressed patients and normal controls. Neuropharmacology 30: 1441-1444.
    • (1991) Neuropharmacology , vol.30 , pp. 1441-1444
    • Roy, A.1
  • 262
    • 0025844780 scopus 로고
    • Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables
    • Roy A, DeJong J, Lamparski D, George T, Linnoila M. 1991. Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables. Arch Gen Psychiatry 48:428-432.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 428-432
    • Roy, A.1    DeJong, J.2    Lamparski, D.3    George, T.4    Linnoila, M.5
  • 264
    • 30844456191 scopus 로고    scopus 로고
    • GABA-based therapeutic approaches: GABAa receptor subtype functions
    • Rudolph U, Mohler H. 2006. GABA-based therapeutic approaches: GABAa receptor subtype functions. Curr Opin Pharmacol 6:1-6.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 1-6
    • Rudolph, U.1    Mohler, H.2
  • 265
    • 0141645449 scopus 로고    scopus 로고
    • Animal models of depression: Challenges from a drug development perspective
    • Rupniak NM. 2003. Animal models of depression: challenges from a drug development perspective. Behav Pharmacol 14:385-390.
    • (2003) Behav Pharmacol , vol.14 , pp. 385-390
    • Rupniak, N.M.1
  • 266
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R. 2003. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 28:139-168.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 139-168
    • Rupprecht, R.1
  • 267
    • 0034646990 scopus 로고    scopus 로고
    • Sodium lactate elicits anxiety in rats after repeated GABA receptor blockade in the basolateral amygdala
    • Sajdyk TJ, Shekhar A. 2000. Sodium lactate elicits anxiety in rats after repeated GABA receptor blockade in the basolateral amygdala. Eur J Pharmacol 394:265-273.
    • (2000) Eur J Pharmacol , vol.394 , pp. 265-273
    • Sajdyk, T.J.1    Shekhar, A.2
  • 269
    • 0034484015 scopus 로고    scopus 로고
    • Impairment of GABAergic transmission in depression: New insights from neuroimaging studies
    • Sanacora G, Mason GF, Krystal JH. 2000. Impairment of GABAergic transmission in depression: new insights from neuroimaging studies. Crit Rev Neurobiol 14:23-45.
    • (2000) Crit Rev Neurobiol , vol.14 , pp. 23-45
    • Sanacora, G.1    Mason, G.F.2    Krystal, J.H.3
  • 270
    • 0036213738 scopus 로고    scopus 로고
    • Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors
    • Sanacora G, Mason GF, Rothman DL, Krystal JH. 2002. Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. Am J Psychiatry 159:663-665.
    • (2002) Am J Psychiatry , vol.159 , pp. 663-665
    • Sanacora, G.1    Mason, G.F.2    Rothman, D.L.3    Krystal, J.H.4
  • 274
    • 0034451667 scopus 로고    scopus 로고
    • The psychobiology of anxiolytic drug. 1. Basic neurobiology
    • Sandford JJ, Argyropoulos SV, Nutt DJ. 2000. The psychobiology of anxiolytic drug. 1. Basic neurobiology. Pharmacol Ther 88: 197-212.
    • (2000) Pharmacol Ther , vol.88 , pp. 197-212
    • Sandford, J.J.1    Argyropoulos, S.V.2    Nutt, D.J.3
  • 275
    • 4644324572 scopus 로고    scopus 로고
    • Effect of antidepressants on GABA(B) receptor function and subunit expression in rat hippocampus
    • Sands SA, Reisman SA, Enna SJ. 2004. Effect of antidepressants on GABA(B) receptor function and subunit expression in rat hippocampus. Biochem Pharmacol 68:1489-1495.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1489-1495
    • Sands, S.A.1    Reisman, S.A.2    Enna, S.J.3
  • 278
    • 25144514487 scopus 로고    scopus 로고
    • Low-dose tiagabine effectiveness in anxiety disorders
    • Schaller JL, Thomas J, Rawlings D. 2004. Low-dose tiagabine effectiveness in anxiety disorders. MedGenMed 6:8.
    • (2004) MedGenMed , vol.6 , pp. 8
    • Schaller, J.L.1    Thomas, J.2    Rawlings, D.3
  • 279
    • 0036342991 scopus 로고    scopus 로고
    • An open case series on the utility of tiagabine as an augmentation in refractory bipolar outpatients
    • Schaffer LC, Schaffer CB, Howe J. 2002. An open case series on the utility of tiagabine as an augmentation in refractory bipolar outpatients. J Affect Disord 71:259-263.
    • (2002) J Affect Disord , vol.71 , pp. 259-263
    • Schaffer, L.C.1    Schaffer, C.B.2    Howe, J.3
  • 280
    • 0018602993 scopus 로고
    • Non-specificity of "behavioral despair" as an animal model of depression
    • Schechter MD, Chance WT. 1979. Non-specificity of "behavioral despair" as an animal model of depression. Eur J Pharmacol 60: 139-142.
    • (1979) Eur J Pharmacol , vol.60 , pp. 139-142
    • Schechter, M.D.1    Chance, W.T.2
  • 281
    • 0018118130 scopus 로고
    • Role of the periaqueductal gray substance in the antianxiety action of benzodiazepines
    • Schenber LC, Graeff FG. 1978. Role of the periaqueductal gray substance in the antianxiety action of benzodiazepines. Pharmacol Biochem Behav 9:287-295.
    • (1978) Pharmacol Biochem Behav , vol.9 , pp. 287-295
    • Schenber, L.C.1    Graeff, F.G.2
  • 282
    • 0032985617 scopus 로고    scopus 로고
    • Effects of GABA-transporter (GAT) inhibitors on rat behavior in open field and elevated plus maze
    • Schmitt U, Hiemke C. 1999. Effects of GABA-transporter (GAT) inhibitors on rat behavior in open field and elevated plus maze. Behav Pharmacol 10:131-137.
    • (1999) Behav Pharmacol , vol.10 , pp. 131-137
    • Schmitt, U.1    Hiemke, C.2
  • 283
    • 0036322305 scopus 로고    scopus 로고
    • Anxiolytic-like effects of acute and chronic GABA transporter inhibition in rats
    • Schmitt U, Luddens H, Hiemke C. 2002. Anxiolytic-like effects of acute and chronic GABA transporter inhibition in rats. J Neural Transm 109:871-880.
    • (2002) J Neural Transm , vol.109 , pp. 871-880
    • Schmitt, U.1    Luddens, H.2    Hiemke, C.3
  • 284
    • 4644231678 scopus 로고    scopus 로고
    • GABA transporters as drug targets for modulation of GABAergic activity
    • Schousboe A, Sarup A, Larsson OM, White HS. 2004. GABA transporters as drug targets for modulation of GABAergic activity. Biochem Pharmacol 68:1557-1563.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1557-1563
    • Schousboe, A.1    Sarup, A.2    Larsson, O.M.3    White, H.S.4
  • 285
    • 0036513861 scopus 로고    scopus 로고
    • The use of tiagabine augmentation for treatment-resistant anxiety disorders: A case series
    • Schwartz TL. 2002. The use of tiagabine augmentation for treatment-resistant anxiety disorders: a case series. Psychopharmacol Bull 36:53-57.
    • (2002) Psychopharmacol Bull , vol.36 , pp. 53-57
    • Schwartz, T.L.1
  • 287
    • 7044237075 scopus 로고    scopus 로고
    • Inactivation of the medial prefrontal cortex with the GABAA receptor agonist muscimol increases open-arm activity in the elevated plus-maze and attenuates shock-probe burying in rats
    • Shah AA, Sjovold T, Treit D. 2004. Inactivation of the medial prefrontal cortex with the GABAA receptor agonist muscimol increases open-arm activity in the elevated plus-maze and attenuates shock-probe burying in rats. Brain Res 1028:112-115.
    • (2004) Brain Res , vol.1028 , pp. 112-115
    • Shah, A.A.1    Sjovold, T.2    Treit, D.3
  • 288
    • 0030272351 scopus 로고    scopus 로고
    • Dorsomedial hypothalamic GABA dysfunction produces physiological arousal following sodium lactate infusions
    • Shekhar A, Keim SR, Simon JR, McBride WJ. 1996. Dorsomedial hypothalamic GABA dysfunction produces physiological arousal following sodium lactate infusions. Pharmacol Biochem Behav 55: 249-256.
    • (1996) Pharmacol Biochem Behav , vol.55 , pp. 249-256
    • Shekhar, A.1    Keim, S.R.2    Simon, J.R.3    McBride, W.J.4
  • 289
    • 0141497898 scopus 로고    scopus 로고
    • Neuroimaging studies of mood disorder effects on the brain
    • Sheline YI. 2003. Neuroimaging studies of mood disorder effects on the brain. Biol Psychiatry 54:338-352.
    • (2003) Biol Psychiatry , vol.54 , pp. 338-352
    • Sheline, Y.I.1
  • 291
    • 0026539430 scopus 로고
    • Direct evidence for mediation of an anticonflict effect of baclofen by GABAb receptors
    • Shephard RA, Wedlock P, Wilson NE. 1992. Direct evidence for mediation of an anticonflict effect of baclofen by GABAb receptors. Pharmacol Biochem Behav 41:651-653.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 651-653
    • Shephard, R.A.1    Wedlock, P.2    Wilson, N.E.3
  • 292
    • 0029655904 scopus 로고
    • Effect of the GABA-transaminase inhibitor vigabatrin on exploratory behavior in socially isolated rats
    • Sherif F, Oreland L. 1995. Effect of the GABA-transaminase inhibitor vigabatrin on exploratory behavior in socially isolated rats. Behav Brain Res 72:135-140.
    • (1995) Behav Brain Res , vol.72 , pp. 135-140
    • Sherif, F.1    Oreland, L.2
  • 293
    • 0032483234 scopus 로고    scopus 로고
    • GABA function in mood disorders: An update and critical review
    • Shiah IS, Yatham LN. 1998. GABA function in mood disorders: an update and critical review. Life Sci 63:1289-1303.
    • (1998) Life Sci , vol.63 , pp. 1289-1303
    • Shiah, I.S.1    Yatham, L.N.2
  • 294
    • 0021170555 scopus 로고
    • Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats
    • Shibata S, Nakanishi H, Watanabe S, Ueki S. 1984. Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats. Pharmacol Biochem Behav 21:225-230.
    • (1984) Pharmacol Biochem Behav , vol.21 , pp. 225-230
    • Shibata, S.1    Nakanishi, H.2    Watanabe, S.3    Ueki, S.4
  • 295
    • 0028981088 scopus 로고
    • Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes
    • Sieghart W. 1995. Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. Pharmacol Rev 47: 181-234.
    • (1995) Pharmacol Rev , vol.47 , pp. 181-234
    • Sieghart, W.1
  • 297
    • 0037441837 scopus 로고    scopus 로고
    • Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs
    • Singewald N, Salchner P, Sharp T. 2003. Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs. Biol Psychiatry 53:275-283.
    • (2003) Biol Psychiatry , vol.53 , pp. 275-283
    • Singewald, N.1    Salchner, P.2    Sharp, T.3
  • 300
    • 0033626831 scopus 로고    scopus 로고
    • Elevated circulatory level of GABA(A) - antagonistic neurosteroids in patients with combat-related posttraumatic stress disorder
    • Spivak B, Maayan R, Kotier M, Mester R, Gil-Ad I, Shtaif B, Weizman A. 2000. Elevated circulatory level of GABA(A) - antagonistic neurosteroids in patients with combat-related posttraumatic stress disorder. Psychol Med 30:1227-1231.
    • (2000) Psychol Med , vol.30 , pp. 1227-1231
    • Spivak, B.1    Maayan, R.2    Kotier, M.3    Mester, R.4    Gil-Ad, I.5    Shtaif, B.6    Weizman, A.7
  • 301
    • 2342457689 scopus 로고    scopus 로고
    • Anticonvulsants as anxiolytics. 1. Tiagabine and other anticonvulsants with actions on GABA
    • Stahl SM. 2004. Anticonvulsants as anxiolytics. 1. Tiagabine and other anticonvulsants with actions on GABA. J Clin Psychiatry 65:291-292.
    • (2004) J Clin Psychiatry , vol.65 , pp. 291-292
    • Stahl, S.M.1
  • 302
  • 303
    • 0037135298 scopus 로고    scopus 로고
    • Reduction of extracellular GABA in the mouse amygdala during and following confrontation with a conditioned fear stimulus
    • Stork O, Ji FY, Obata K. 2002. Reduction of extracellular GABA in the mouse amygdala during and following confrontation with a conditioned fear stimulus. Neurosci Lett 327:138-142.
    • (2002) Neurosci Lett , vol.327 , pp. 138-142
    • Stork, O.1    Ji, F.Y.2    Obata, K.3
  • 304
    • 0036115945 scopus 로고    scopus 로고
    • Volumetric MRI studies of mood disorders: Do they distinguish unipolar and bipolar disorder?
    • Strakowski SM, Adler CM, DelBello MP. 2002. Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? Bipolar Disord 4:80-88.
    • (2002) Bipolar Disord , vol.4 , pp. 80-88
    • Strakowski, S.M.1    Adler, C.M.2    DelBello, M.P.3
  • 305
    • 17044444204 scopus 로고    scopus 로고
    • Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery
    • Strohle A, Romeo E, Hermann B, Pasini A, Spalletta G, di Michele F, Holsboer F, Rupprecht R. 1999. Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery. Biol Psychiatry 45:274-277.
    • (1999) Biol Psychiatry , vol.45 , pp. 274-277
    • Strohle, A.1    Romeo, E.2    Hermann, B.3    Pasini, A.4    Spalletta, G.5    di Michele, F.6    Holsboer, F.7    Rupprecht, R.8
  • 306
    • 0031017032 scopus 로고    scopus 로고
    • GABA uptake sites in frontal cortex from suicide victims and in aging
    • Sundman I, Allard P, Eriksson A, Marcusson J. 1997. GABA uptake sites in frontal cortex from suicide victims and in aging. Neuropsychobiology 35:11-15.
    • (1997) Neuropsychobiology , vol.35 , pp. 11-15
    • Sundman, I.1    Allard, P.2    Eriksson, A.3    Marcusson, J.4
  • 307
    • 0036345847 scopus 로고    scopus 로고
    • 3]H)Tiagabine binding to GABA transporter-1 (GAT-I) in suicidal depression
    • Sundman-Eriksson I, Allard P. 2002. ([3]H)Tiagabine binding to GABA transporter-1 (GAT-I) in suicidal depression. J Affect Disord 71:29-33.
    • (2002) J Affect Disord , vol.71 , pp. 29-33
    • Sundman-Eriksson, I.1    Allard, P.2
  • 308
    • 0030889591 scopus 로고    scopus 로고
    • Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: A pilot study
    • Sundstrom I, Ashbrook D, Backstrom T. 1997. Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study. Psychoneuroendocrinology 22:25-38.
    • (1997) Psychoneuroendocrinology , vol.22 , pp. 25-38
    • Sundstrom, I.1    Ashbrook, D.2    Backstrom, T.3
  • 310
    • 0033664540 scopus 로고    scopus 로고
    • Influence of antiepileptics on efficacy of antidepressant drugs in forced swimming test
    • Szymczyk G, Zebrowska-Lupina I. 2000. Influence of antiepileptics on efficacy of antidepressant drugs in forced swimming test. Pol J Pharmacol 52:337-344.
    • (2000) Pol J Pharmacol , vol.52 , pp. 337-344
    • Szymczyk, G.1    Zebrowska-Lupina, I.2
  • 311
  • 312
    • 0034989926 scopus 로고    scopus 로고
    • Common effects of chronically administered antipanic drugs on brainstem GABAA receptor subunit gene expression
    • Tanay VAMI, Greenshaw AJ, Baker GB, Bateson AN. 2001. Common effects of chronically administered antipanic drugs on brainstem GABAA receptor subunit gene expression. Mol Psychiatry 6:404-412.
    • (2001) Mol Psychiatry , vol.6 , pp. 404-412
    • Tanay, V.A.M.I.1    Greenshaw, A.J.2    Baker, G.B.3    Bateson, A.N.4
  • 313
    • 0037409861 scopus 로고    scopus 로고
    • Central GABAergic systems and depressive illness
    • Tunnicliff G, Malatynska E. 2003. Central GABAergic systems and depressive illness. Neurochem Res 28:965-976.
    • (2003) Neurochem Res , vol.28 , pp. 965-976
    • Tunnicliff, G.1    Malatynska, E.2
  • 314
    • 0024517220 scopus 로고
    • Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates
    • Turner DM, Ransom RW, Yang JS, Olsen RW. 1989. Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates. J Pharmacol Exp Ther 248:960-966.
    • (1989) J Pharmacol Exp Ther , vol.248 , pp. 960-966
    • Turner, D.M.1    Ransom, R.W.2    Yang, J.S.3    Olsen, R.W.4
  • 316
    • 0032814240 scopus 로고    scopus 로고
    • Effects of psychoactive drugs in the Vogel conflict test in mice
    • Umezu T 1999. Effects of psychoactive drugs in the Vogel conflict test in mice. Jpn J Pharmacol 80:111-118.
    • (1999) Jpn J Pharmacol , vol.80 , pp. 111-118
    • Umezu, T.1
  • 318
    • 0034891123 scopus 로고    scopus 로고
    • The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test
    • Urani A, Roman FJ, Phan VL, Su TP, Maurice T. 2001. The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test. J Pharmacol Exp Ther 298:1269-1279.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1269-1279
    • Urani, A.1    Roman, F.J.2    Phan, V.L.3    Su, T.P.4    Maurice, T.5
  • 319
    • 19944386640 scopus 로고    scopus 로고
    • Mutant mouse models of depression: Candidate genes and current mouse lines
    • Urani A, Chourbaji S, Gass P. 2005. Mutant mouse models of depression: candidate genes and current mouse lines. Neurosci Biobehav Rev 29:805-828.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 805-828
    • Urani, A.1    Chourbaji, S.2    Gass, P.3
  • 320
    • 0029970863 scopus 로고    scopus 로고
    • Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography
    • Uzunov DP, Cooper TB, Costa E, Guidotti A. 1996. Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography. Proc Natl Acad Sci USA 93: 12599-12604.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12599-12604
    • Uzunov, D.P.1    Cooper, T.B.2    Costa, E.3    Guidotti, A.4
  • 321
    • 0032539862 scopus 로고    scopus 로고
    • Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine
    • Uzunova V, Sheline Y, Davis JM, Rasmusson A, Uzunov DP, Costa E, Guidotti A. 1998. Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proc Natl Acad Sci USA 95: 3239-3244.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3239-3244
    • Uzunova, V.1    Sheline, Y.2    Davis, J.M.3    Rasmusson, A.4    Uzunov, D.P.5    Costa, E.6    Guidotti, A.7
  • 322
    • 0038743129 scopus 로고    scopus 로고
    • Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression
    • Uzunova V, Ceci M, Kohler C, Uzunov DP, Wrynn AS. 2003. Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression. Brain Res 976: 1-8.
    • (2003) Brain Res , vol.976 , pp. 1-8
    • Uzunova, V.1    Ceci, M.2    Kohler, C.3    Uzunov, D.P.4    Wrynn, A.S.5
  • 323
    • 1642564005 scopus 로고    scopus 로고
    • Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat
    • Uzunova V, Wrynn AS, Kinnunen A, Ceci M, Kohler C, Uzunov DP. 2004. Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat. Eur J Pharmacol 486:31-34.
    • (2004) Eur J Pharmacol , vol.486 , pp. 31-34
    • Uzunova, V.1    Wrynn, A.S.2    Kinnunen, A.3    Ceci, M.4    Kohler, C.5    Uzunov, D.P.6
  • 325
    • 36049039633 scopus 로고    scopus 로고
    • The role of a6 subunit-containing GABAa receptors in behavioral effects of alcohol and drug treatments
    • Vekovisheva OYu. 2003. The role of a6 subunit-containing GABAa receptors in behavioral effects of alcohol and drug treatments. Acta Univer Tamper 928:1-58.
    • (2003) Acta Univer Tamper , vol.928 , pp. 1-58
    • Vekovisheva, O.Y.1
  • 326
    • 4644281673 scopus 로고    scopus 로고
    • Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus
    • Verkuyl JM, Hemby SE, Joels M. 2004. Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus. Eur J Neurosci 20:1665-1673.
    • (2004) Eur J Neurosci , vol.20 , pp. 1665-1673
    • Verkuyl, J.M.1    Hemby, S.E.2    Joels, M.3
  • 327
    • 0041508228 scopus 로고    scopus 로고
    • Villafuerte S, Burmeister M. 2003. Untangling genetic networks of panic, phobia, fear and anxiety. Genome Biol 4:224.1-4.
    • Villafuerte S, Burmeister M. 2003. Untangling genetic networks of panic, phobia, fear and anxiety. Genome Biol 4:224.1-4.
  • 328
    • 29444435441 scopus 로고    scopus 로고
    • Clinical use of carbamazepine for bipolar disorders
    • Wang PW, Ketter TA. 2005. Clinical use of carbamazepine for bipolar disorders. Expert Opin Pharmacother 6:2887-2902.
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 2887-2902
    • Wang, P.W.1    Ketter, T.A.2
  • 331
    • 0038178996 scopus 로고    scopus 로고
    • GABA-A receptor subtypes in the brain: A paradigm for CNS drug discovery?
    • Whiting PJ. 2003. GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery? Drug Discov Today 8: 445-450.
    • (2003) Drug Discov Today , vol.8 , pp. 445-450
    • Whiting, P.J.1
  • 333
    • 17844368896 scopus 로고    scopus 로고
    • Quantitative analysis of immunolabeling for serotonin and for glutamate transporters after administration of imipramine and citalopram
    • Williams SM, Bryan-Lluka LJ, Pow DV. 2005. Quantitative analysis of immunolabeling for serotonin and for glutamate transporters after administration of imipramine and citalopram. Brain Res 1042: 224-232.
    • (2005) Brain Res , vol.1042 , pp. 224-232
    • Williams, S.M.1    Bryan-Lluka, L.J.2    Pow, D.V.3
  • 334
    • 1242263295 scopus 로고    scopus 로고
    • From monoamines to genomic targets: A paradigm shift for drug discovery in depression
    • Wong ML, Licinio J. 2004. From monoamines to genomic targets: a paradigm shift for drug discovery in depression. Nat Rev Drug Discov 3:136-151.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 136-151
    • Wong, M.L.1    Licinio, J.2
  • 336
    • 0142011582 scopus 로고    scopus 로고
    • Evidence of association between γ-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders
    • Yamada K, Watanabe A, Iwayama-Shigeno Y, Yoshikawa T. 2003. Evidence of association between γ-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders. Neurosci Lett 349:9-12.
    • (2003) Neurosci Lett , vol.349 , pp. 9-12
    • Yamada, K.1    Watanabe, A.2    Iwayama-Shigeno, Y.3    Yoshikawa, T.4
  • 337
    • 26044445491 scopus 로고    scopus 로고
    • In vivo evidence for reduced cortical glutamate-glutamine cycling in rats treated with the antidepressant/antipanic drug phenelzine
    • Yang J, Shen J. 2005. In vivo evidence for reduced cortical glutamate-glutamine cycling in rats treated with the antidepressant/antipanic drug phenelzine. Neuroscience 135:927-937.
    • (2005) Neuroscience , vol.135 , pp. 927-937
    • Yang, J.1    Shen, J.2
  • 338
    • 0141645539 scopus 로고    scopus 로고
    • Anxiety-related behavior and densities of glutamate, GABAA, acetylcholine and serotonin receptors in the amygdala of seven inbred mouse strains
    • Yilmazer-Hanke DM, Roskoden T, Zilles K, Schwegler H. 2003. Anxiety-related behavior and densities of glutamate, GABAA, acetylcholine and serotonin receptors in the amygdala of seven inbred mouse strains. Behav Brain Res 145:145-159.
    • (2003) Behav Brain Res , vol.145 , pp. 145-159
    • Yilmazer-Hanke, D.M.1    Roskoden, T.2    Zilles, K.3    Schwegler, H.4
  • 339
    • 0036119371 scopus 로고    scopus 로고
    • Identification of multiple genetic loci linked to the propensity for "behavioral despair" in mice
    • Yoshikawa T, Watanabe A, Ishitsuka Y, Nakaya A, Nakatani N. 2002. Identification of multiple genetic loci linked to the propensity for "behavioral despair" in mice. Genome Res 12:357-366.
    • (2002) Genome Res , vol.12 , pp. 357-366
    • Yoshikawa, T.1    Watanabe, A.2    Ishitsuka, Y.3    Nakaya, A.4    Nakatani, N.5
  • 341
    • 0034988351 scopus 로고    scopus 로고
    • GABA(A) but not GABA(B) receptor stimulation induces antianxiety profile in rats
    • Zarrindast M, Rostami P, Sadeghi-Hariri M. 2001. GABA(A) but not GABA(B) receptor stimulation induces antianxiety profile in rats. Pharmacol Biochem Behav 69:9-15.
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 9-15
    • Zarrindast, M.1    Rostami, P.2    Sadeghi-Hariri, M.3
  • 343
    • 16244377706 scopus 로고    scopus 로고
    • Differences in affective behaviors and hippocampal allopregnanolone levels in adult rats of lines selectively bred for infantile vocalizations
    • Zimmerberg B, Brunelli SA, Fluty AJ, Frye CA. 2005. Differences in affective behaviors and hippocampal allopregnanolone levels in adult rats of lines selectively bred for infantile vocalizations. Behav Brain Res 159:301-311.
    • (2005) Behav Brain Res , vol.159 , pp. 301-311
    • Zimmerberg, B.1    Brunelli, S.A.2    Fluty, A.J.3    Frye, C.A.4
  • 344
    • 21744438753 scopus 로고    scopus 로고
    • Selective GABAergic treatment for panic? Investigations in experimental panic induction and panic disorder
    • Zwanzger P, Rupprecht R. 2005. Selective GABAergic treatment for panic? Investigations in experimental panic induction and panic disorder. J Psychiatry Neurosci 30:167-175.
    • (2005) J Psychiatry Neurosci , vol.30 , pp. 167-175
    • Zwanzger, P.1    Rupprecht, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.