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Volumn 13, Issue 5, 2012, Pages 535-557

Metabolite profiling and characterization for medicinal herbal remedies

Author keywords

Complex system; Hyphenated technique; Identification; Medicinal herbal remedy; Metabolite; Nuclear magnetic resonance; Preparation; Tandem mass spectrometry

Indexed keywords

ALKALOID DERIVATIVE; ANTHRAQUINONE; BERBERINE; CATECHIN; CHINESE DRUG; CHLOROGENIC ACID; CROCETIN; DANGGUI BUXUE TANG; DAURICINE; DICENTRINE; DIHYDROCAFFEIC ACID; DRUG METABOLITE; FLAVONOID; HERBACEOUS AGENT; ISOLIQUIRITIGENIN; LIQUIRITIGENIN; METHANOL; MONOTERPENOID; PHENYLBUTENOID; PHY 906; PLANT EXTRACT; RUTAECARPINE; SCOPOLAMINE; SCUTELLARIN; SESQUITERPENOID; TANSHINONE; TERPENOID DERIVATIVE; TRITERPENE; TRYPTANTHRIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84861890620     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200211209050535     Document Type: Article
Times cited : (25)

References (163)
  • 1
    • 0030988773 scopus 로고    scopus 로고
    • Chromatographic identification of phenolic compounds in human urine following oral administration of the herbal medicines Daisaiko-to and Shosaiko-to
    • Li, C.; Homma, M.; Oka, K. Chromatographic identification of phenolic compounds in human urine following oral administration of the herbal medicines Daisaiko-to and Shosaiko-to. J. Chromatogr. B, 1997, 693(1), 191-198.
    • (1997) J. Chromatogr. B , vol.693 , Issue.1 , pp. 191-198
    • Li, C.1    Homma, M.2    Oka, K.3
  • 2
    • 0030934350 scopus 로고    scopus 로고
    • (S)-Dihydrooroxylin A in human urine following oral administration of the traditional Chinese medicines: Daisaiko-to and Shosaiko-to
    • Li, C.; Homma, M.; Ohkura, N.; Oka, K. (S)-Dihydrooroxylin A in human urine following oral administration of the traditional Chinese medicines: Daisaiko-to and Shosaiko-to. Tetrahedron: Asymmetry, 1997, 8(8), 1145-1147.
    • (1997) Tetrahedron: Asymmetry , vol.8 , Issue.8 , pp. 1145-1147
    • Li, C.1    Homma, M.2    Ohkura, N.3    Oka, K.4
  • 3
    • 34248582576 scopus 로고    scopus 로고
    • Analytical strategies for identifying drug metabolites
    • Prakash, C.; Shaffer, C.L.; Nedderman, A. Analytical strategies for identifying drug metabolites. Mass Spectrom. Rev., 2007, 26(3), 340-369.
    • (2007) Mass Spectrom. Rev. , vol.26 , Issue.3 , pp. 340-369
    • Prakash, C.1    Shaffer, C.L.2    Nedderman, A.3
  • 4
    • 67650494794 scopus 로고    scopus 로고
    • Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry
    • Zhang, H.Y.; Zhang, D.L.; Ray, K.; Zhu, M.S. Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry. J. Mass Spectrom., 2009, 44(7), 999-1016.
    • (2009) J. Mass Spectrom. , vol.44 , Issue.7 , pp. 999-1016
    • Zhang, H.Y.1    Zhang, D.L.2    Ray, K.3    Zhu, M.S.4
  • 5
    • 48749115768 scopus 로고    scopus 로고
    • Mass spectrometry for the identification of the discriminating signals from metabolomics: Current status and future trends
    • Werner, E.; Heilier, J.F.; Ducruix, C.; Ezan, E.; Junot, C.; Tabet, J.C. Mass spectrometry for the identification of the discriminating signals from metabolomics: Current status and future trends. J. Chromatogr. B, 2008, 871(2), 143-163.
    • (2008) J. Chromatogr. B , vol.871 , Issue.2 , pp. 143-163
    • Werner, E.1    Heilier, J.F.2    Ducruix, C.3    Ezan, E.4    Junot, C.5    Tabet, J.C.6
  • 6
    • 77950627695 scopus 로고    scopus 로고
    • Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification
    • Ohta, D.; Kanaya, S.; Suzuki, H. Application of Fourier-transform ion cyclotron resonance mass spectrometry to metabolic profiling and metabolite identification. Curr. Opin. Biotechnol., 2010, 21(1), 1-10.
    • (2010) Curr. Opin. Biotechnol. , vol.21 , Issue.1 , pp. 1-10
    • Ohta, D.1    Kanaya, S.2    Suzuki, H.3
  • 7
    • 48849114188 scopus 로고    scopus 로고
    • Gas chromatography/mass spectrometry in metabolic profiling of biological fluids
    • Pasikanti, K.K.; Ho, P.C.; Chan, E.C.Y. Gas chromatography/mass spectrometry in metabolic profiling of biological fluids. J. Chromatogr. B, 2008, 871(2), 202-211.
    • (2008) J. Chromatogr. B , vol.871 , Issue.2 , pp. 202-211
    • Pasikanti, K.K.1    Ho, P.C.2    Chan, E.C.Y.3
  • 8
    • 0037649064 scopus 로고    scopus 로고
    • Liquid chromatography/atmospheric pressure ionization-mass spectrometry in drug metabolism studies
    • Kostiainen, R.; Kotiaho, T.; Kuuranne, T.; Auriola, S. Liquid chromatography/atmospheric pressure ionization-mass spectrometry in drug metabolism studies. J. Mass Spectrom., 2003, 38(4), 357-372.
    • (2003) J. Mass Spectrom. , vol.38 , Issue.4 , pp. 357-372
    • Kostiainen, R.1    Kotiaho, T.2    Kuuranne, T.3    Auriola, S.4
  • 9
    • 58849124556 scopus 로고    scopus 로고
    • Liquid chromatographymass spectrometry in in vitro drug metabolite screening
    • Tolonen, A.; Turpeinen, M.; Pelkonen, O. Liquid chromatographymass spectrometry in in vitro drug metabolite screening. Drug Discov. Today, 2009, 14(3-4), 120-133.
    • (2009) Drug Discov. Today , vol.14 , Issue.3-4 , pp. 120-133
    • Tolonen, A.1    Turpeinen, M.2    Pelkonen, O.3
  • 10
    • 59649106977 scopus 로고    scopus 로고
    • Recent advances in applications of liquid chromatography-tandem mass spectrometry to the analysis of reactive drug metabolites
    • Ma, S.G.; Zhu, M.S. Recent advances in applications of liquid chromatography-tandem mass spectrometry to the analysis of reactive drug metabolites. Chem. Biol. Interact., 2009, 179(1), 25-37.
    • (2009) Chem. Biol. Interact. , vol.179 , Issue.1 , pp. 25-37
    • Ma, S.G.1    Zhu, M.S.2
  • 11
    • 34547344360 scopus 로고    scopus 로고
    • New analytical strategies in studying drug metabolism
    • Staack, R.F.; Hopfgartner, G. New analytical strategies in studying drug metabolism. Anal. Bioanal. Chem., 2007, 388(7), 1365-1380.
    • (2007) Anal. Bioanal. Chem. , vol.388 , Issue.7 , pp. 1365-1380
    • Staack, R.F.1    Hopfgartner, G.2
  • 12
    • 42449153666 scopus 로고    scopus 로고
    • High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase i and phase II drug metabolites
    • Holčapek, M.; Kolářová, L.; Nobilis, M. High-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites. Anal. Bioanal. Chem., 2008, 391(1), 59-78.
    • (2008) Anal. Bioanal. Chem. , vol.391 , Issue.1 , pp. 59-78
    • Holčapek, M.1    Kolářová, L.2    Nobilis, M.3
  • 13
    • 34250013402 scopus 로고    scopus 로고
    • Application of LC-MS for quantitative analysis and metabolite identification of therapeutic oligonucleotides
    • Lin, Z.P.; Li, W.K.; Dai, D.W. Application of LC-MS for quantitative analysis and metabolite identification of therapeutic oligonucleotides. J. Pharm. Biomed. Anal., 2007, 44(2), 330-341.
    • (2007) J. Pharm. Biomed. Anal. , vol.44 , Issue.2 , pp. 330-341
    • Lin, Z.P.1    Li, W.K.2    Dai, D.W.3
  • 14
    • 12344263826 scopus 로고    scopus 로고
    • Strategies for characterization of drug metabolites using liquid chromatography-tandem mass spectrometry in conjunction with chemical derivatization and on-line H/D exchange approaches
    • Liu, D.Q.; Hop, C.E. Strategies for characterization of drug metabolites using liquid chromatography-tandem mass spectrometry in conjunction with chemical derivatization and on-line H/D exchange approaches. J. Pharm. Biomed. Anal., 2005, 37(1), 1-18.
    • (2005) J. Pharm. Biomed. Anal. , vol.37 , Issue.1 , pp. 1-18
    • Liu, D.Q.1    Hop, C.E.2
  • 15
    • 13244264923 scopus 로고    scopus 로고
    • Metabolite fingerprinting and profiling in plants using NMR
    • Krishnan, P.; Kruger, N. J.; Ratcliffe, R.G. Metabolite fingerprinting and profiling in plants using NMR. J. Exp. Bot., 2005, 56(410), 255-265.
    • (2005) J. Exp. Bot. , vol.56 , Issue.410 , pp. 255-265
    • Krishnan, P.1    Kruger, N.J.2    Ratcliffe, R.G.3
  • 16
    • 0034306770 scopus 로고    scopus 로고
    • Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development J
    • Lindon, L.C.; Nicholson, J.K.; Wilson, I.D. Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development J. Chromatogr. B, 2000, 748(1), 233-258.
    • (2000) Chromatogr. B , vol.748 , Issue.1 , pp. 233-258
    • Lindon, L.C.1    Nicholson, J.K.2    Wilson, I.D.3
  • 17
    • 32444441286 scopus 로고    scopus 로고
    • Online hyphenated liquid chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry for drug metabolite and nature product analysis
    • Yang, Z. Online hyphenated liquid chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry for drug metabolite and nature product analysis. J. Pharm. Biomed. Anal., 2006, 40(3), 516-527.
    • (2006) J. Pharm. Biomed. Anal. , vol.40 , Issue.3 , pp. 516-527
    • Yang, Z.1
  • 18
    • 31844437109 scopus 로고    scopus 로고
    • Progress in capillary electrophoresis of biomarkers and metabolites between 2002 and 2005
    • Huck, C.W.; Bakry, R.; Bonn, G.K. Progress in capillary electrophoresis of biomarkers and metabolites between 2002 and 2005. Electrophoresis, 2006, 27(1), 111-125.
    • (2006) Electrophoresis , vol.27 , Issue.1 , pp. 111-125
    • Huck, C.W.1    Bakry, R.2    Bonn, G.K.3
  • 21
    • 67649385775 scopus 로고    scopus 로고
    • Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry
    • Grata, E.; Guillarme, D.; Glauser, G.; Boccard, J.; Carrupt, P.A.; Veuthey, J.L.; Rudaz, S.; Wolfender, J.L. Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry. J. Chromatogr. A, 2009, 1216(30), 5660-5668.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.30 , pp. 5660-5668
    • Grata, E.1    Guillarme, D.2    Glauser, G.3    Boccard, J.4    Carrupt, P.A.5    Veuthey, J.L.6    Rudaz, S.7    Wolfender, J.L.8
  • 22
    • 41549102932 scopus 로고    scopus 로고
    • Identification of novel metabolites of colchicine in rat bile facilitated by enhanced online radiometric detection
    • Xu, L.; Adams, B.; Jeliazkova-Mecheva, V.V.; Trimble, L.; Kwei, G.; Harsch, A. Identification of novel metabolites of colchicine in rat bile facilitated by enhanced online radiometric detection. Drug Metab. Dispos., 2008, 36(4), 731-739.
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.4 , pp. 731-739
    • Xu, L.1    Adams, B.2    Jeliazkova-Mecheva, V.V.3    Trimble, L.4    Kwei, G.5    Harsch, A.6
  • 23
    • 79953659132 scopus 로고    scopus 로고
    • Recent development in liquid chromatography/mass spectrometry and emerging technologies for metabolite identification
    • Liang, Y.; Wang, G.J.; Xie, L.; Sheng, L.S. Recent development in liquid chromatography/mass spectrometry and emerging technologies for metabolite identification. Curr. Drug Metab., 2011, 12(4), 329-344.
    • (2011) Curr. Drug Metab. , vol.12 , Issue.4 , pp. 329-344
    • Liang, Y.1    Wang, G.J.2    Xie, L.3    Sheng, L.S.4
  • 24
    • 41149180635 scopus 로고    scopus 로고
    • High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry
    • Wen, B.; Ma, L.; Nelson, S.D.; Zhu, M.S. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry. Anal. Chem., 2008, 80(5), 1788-1799.
    • (2008) Anal. Chem. , vol.80 , Issue.5 , pp. 1788-1799
    • Wen, B.1    Ma, L.2    Nelson, S.D.3    Zhu, M.S.4
  • 25
    • 46849091191 scopus 로고    scopus 로고
    • Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection
    • Zhang, H.Y.; Zhu, M.S.; Ray, K.L.; Ma, L.; Zhang, D.L. Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection. Rapid Commun. Mass Spectrom., 2008, 22(13), 2082-2088.
    • (2008) Rapid Commun. Mass Spectrom. , vol.22 , Issue.13 , pp. 2082-2088
    • Zhang, H.Y.1    Zhu, M.S.2    Ray, K.L.3    Ma, L.4    Zhang, D.L.5
  • 26
    • 60349129230 scopus 로고    scopus 로고
    • Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry
    • Yang, M.; Sun, J.H.; Lu, Z.Q.; Chen, G.T.; Guan, S.H.; Liu, X.; Jiang, B.H.; Ye, M.; Guo, D.A. Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J. Chromatogr. A, 2009, 1216(11), 2045-2062.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2045-2062
    • Yang, M.1    Sun, J.H.2    Lu, Z.Q.3    Chen, G.T.4    Guan, S.H.5    Liu, X.6    Jiang, B.H.7    Ye, M.8    Guo, D.A.9
  • 27
    • 34447635677 scopus 로고    scopus 로고
    • Detection characterization and identification of phenolic acids in Danshen using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry
    • Liu, A.H.; Guo, H.; Ye, M.; Lin, Y.H.; Sun, J.H.; Xu, M.; Guo, D.A. Detection, characterization and identification of phenolic acids in Danshen using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry. J. Chromatogr. A, 2007, 1161(1-2), 170-182.
    • (2007) J. Chromatogr. A , vol.1161 , Issue.1-2 , pp. 170-182
    • Liu, A.H.1    Guo, H.2    Ye, M.3    Lin, Y.H.4    Sun, J.H.5    Xu, M.6    Guo, D.A.7
  • 28
    • 33645840150 scopus 로고    scopus 로고
    • Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
    • Yang, M.; Liu, A.H.; Guan, S.H.; Sun, J.H.; Xu, M.; Guo, D.A. Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom, 2006, 20(8), 1266-1280.
    • (2006) Rapid Commun. Mass Spectrom , vol.20 , Issue.8 , pp. 1266-1280
    • Yang, M.1    Liu, A.H.2    Guan, S.H.3    Sun, J.H.4    Xu, M.5    Guo, D.A.6
  • 29
    • 33847392883 scopus 로고    scopus 로고
    • Characterization of phenolic compounds in the fruits of Forsythia suspensa by highperformance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
    • Guo, H.; Liu, A.H.; Ye, M.; Yang, M.; Guo, D.A. Characterization of phenolic compounds in the fruits of Forsythia suspensa by highperformance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2007, 21(5), 715-729.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , Issue.5 , pp. 715-729
    • Guo, H.1    Liu, A.H.2    Ye, M.3    Yang, M.4    Guo, D.A.5
  • 30
    • 26844499175 scopus 로고    scopus 로고
    • Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high-performance liquid chromatography/ electrospray ionization mass spectrometry
    • Jiang, H.L.; Sólyom, A.M.; Timmermann, B.N.; Gang, D.R. Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom., 2005, 19(20), 2957-2964.
    • (2005) Rapid Commun. Mass Spectrom. , vol.19 , Issue.20 , pp. 2957-2964
    • Jiang, H.L.1    Sólyom, A.M.2    Timmermann, B.N.3    Gang, D.R.4
  • 31
    • 33847092619 scopus 로고    scopus 로고
    • Characterization and identification of diarylheptanoids in ginger (Zingiber officinale Rosc.) using high-performance liquid chromatography/ electrospray ionization mass spectrometry
    • Jiang, H.L.; Timmermann, B.N.; Gang, D.R. Characterization and identification of diarylheptanoids in ginger (Zingiber officinale Rosc.) using high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21(4), 509-518.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , Issue.4 , pp. 509-518
    • Jiang, H.L.1    Timmermann, B.N.2    Gang, D.R.3
  • 32
    • 0032791155 scopus 로고    scopus 로고
    • Liquid chromatography-electrospray mass spectrometric identification of ginsenosides in Panax ginseng roots
    • Fuzzati, N.; Gabetta, B.; Jayakar, K.; Pace, R.; Peterlongo, F. Liquid chromatography-electrospray mass spectrometric identification of ginsenosides in Panax ginseng roots. J. Chromatogr. A, 1999, 854(1-2), 69-79.
    • (1999) J. Chromatogr. A , vol.854 , Issue.1-2 , pp. 69-79
    • Fuzzati, N.1    Gabetta, B.2    Jayakar, K.3    Pace, R.4    Peterlongo, F.5
  • 33
    • 0037254722 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry of malonyl-ginsenosides in the authentication of ginseng
    • Kite, G.C.; Howes, M.R.; Leon, C.J.; Simmonds, M.S.J. Liquid chromatography/mass spectrometry of malonyl-ginsenosides in the authentication of ginseng. Rapid Commun. Mass Spectrom. 2003, 17(3), 238-244.
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , Issue.3 , pp. 238-244
    • Kite, G.C.1    Howes, M.R.2    Leon, C.J.3    Simmonds, M.S.J.4
  • 34
    • 33947613641 scopus 로고    scopus 로고
    • Application of atmospheric pressure chemical ionisation mass spectrometry in the identification and differentiation of Panax species
    • Leung, K.S.; Chan, K.; Bensoussan, A.; Munroe, M.J. Application of atmospheric pressure chemical ionisation mass spectrometry in the identification and differentiation of Panax species. Phytochem. Anal., 2007, 18(2), 146-150.
    • (2007) Phytochem. Anal. , vol.18 , Issue.2 , pp. 146-150
    • Leung, K.S.1    Chan, K.2    Bensoussan, A.3    Munroe, M.J.4
  • 35
    • 33847126285 scopus 로고    scopus 로고
    • Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng
    • Chan, E.C.; Yap, S.L.; Lau, A.J.; Leow, P.C.; Toh, D.F.; Koh, H.L. Ultra-performance liquid chromatography/time-of-flight mass spectrometry based metabolomics of raw and steamed Panax notoginseng. Rapid Commun. Mass Spectrom., 2007, 21(4), 519-528.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , Issue.4 , pp. 519-528
    • Chan, E.C.1    Yap, S.L.2    Lau, A.J.3    Leow, P.C.4    Toh, D.F.5    Koh, H.L.6
  • 36
    • 34247181278 scopus 로고    scopus 로고
    • Analysis of triterpenoids in ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry
    • Yang, M.; Wang, X.M.; Guan, S.H.; Xia, J.M.; Sun, J.H.; Guo, H.; Guo, D.A. Analysis of triterpenoids in ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom., 2007, 18(5), 927-939.
    • (2007) J. Am. Soc. Mass Spectrom. , vol.18 , Issue.5 , pp. 927-939
    • Yang, M.1    Wang, X.M.2    Guan, S.H.3    Xia, J.M.4    Sun, J.H.5    Guo, H.6    Guo, D.A.7
  • 37
    • 79952110549 scopus 로고    scopus 로고
    • Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry
    • Wang, B.; Chu, W.Y.; Li, Z.; Hou, J.Q.; Huang, S.L.; Ou, T.M.; Tan, J.H.; An, L.K.; Li, D.; Gu, L.Q.; Huang, Z.S. Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2010, 24(18), 2781-2786.
    • (2010) Rapid Commun. Mass Spectrom. , vol.24 , Issue.18 , pp. 2781-2786
    • Wang, B.1    Chu, W.Y.2    Li, Z.3    Hou, J.Q.4    Huang, S.L.5    Ou, T.M.6    Tan, J.H.7    An, L.K.8    Li, D.9    Gu, L.Q.10    Huang, Z.S.11
  • 39
    • 73249153043 scopus 로고    scopus 로고
    • Studies on the homolytic and heterolytic cleavage of kaempferol and kaempferide glycosides using electrospray ionization tandem mass spectrometry
    • Lu, L.; Song, F.R.; Tsao, R.; Jin, Y.R.; Liu, Z.Q.; Liu, S.Y. Studies on the homolytic and heterolytic cleavage of kaempferol and kaempferide glycosides using electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2010, 24(1), 169-172.
    • (2010) Rapid Commun. Mass Spectrom. , vol.24 , Issue.1 , pp. 169-172
    • Lu, L.1    Song, F.R.2    Tsao, R.3    Jin, Y.R.4    Liu, Z.Q.5    Liu, S.Y.6
  • 40
    • 60149092958 scopus 로고    scopus 로고
    • Electrospray ionization tandem mass spectrometry fragmentationof protonated flavone and flavonol aglycones: A re-examination
    • Justino, G.C.; Borges C.M.; Florêncio, M.H. Electrospray ionization tandem mass spectrometry fragmentationof protonated flavone and flavonol aglycones: a re-examination. Rapid Commun. Mass Spectrom., 2009, 23(2), 237-248.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.2 , pp. 237-248
    • Justino, G.C.1    Borges, C.M.2    Florêncio, M.H.3
  • 41
    • 64149126493 scopus 로고    scopus 로고
    • Study of active naphtodianthrone St John's Wortcompounds by electrospray ionization Fourier transform ion cyclotron resonance and multi-stage mass spectrometry in sustained off-resonance irradiation collisioninduced dissociation and infrared multiphoton dissociation modes
    • Hecka, A.; Maunit, B.; Aubriet F.; Muller, J.F. Study of active naphtodianthrone St John's Wortcompounds by electrospray ionization Fourier transform ion cyclotron resonance and multi-stage mass spectrometry in sustained off-resonance irradiation collisioninduced dissociation and infrared multiphoton dissociation modes. Rapid Commun. Mass Spectrom., 2009, 23(6), 885-898.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.6 , pp. 885-898
    • Hecka, A.1    Maunit, B.2    Aubriet, F.3    Muller, J.F.4
  • 42
    • 69449090205 scopus 로고    scopus 로고
    • An investigation of the fragmentation differences of isomeric flavonol-Oglycosides under different collision-induced dissociation based mass spectrometry
    • Geng, P.; Sun, J.H.; Zhang, R.P.; He J.M.; Abliz, Z. An investigation of the fragmentation differences of isomeric flavonol-Oglycosides under different collision-induced dissociation based mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(10), 1519-1524.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.10 , pp. 1519-1524
    • Geng, P.1    Sun, J.H.2    Zhang, R.P.3    He, J.M.4    Abliz, Z.5
  • 43
    • 67650376031 scopus 로고    scopus 로고
    • Positive electrospray ionization tandem mass spectrometry of polymethoxylated flavones
    • Wang, K.W.; Zhang, H. Positive electrospray ionization tandem mass spectrometry of polymethoxylated flavones. Rapid Commun. Mass Spectrom., 2009, 23(13), 2107-2111.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.13 , pp. 2107-2111
    • Wang, K.W.1    Zhang, H.2
  • 44
    • 70449380273 scopus 로고    scopus 로고
    • Rapid differentiation of isobaric and positional isomers of structurally related glycosides from Phytolacca bogotensis
    • Montoya, G.; Arango, G.J.; Ramírez-Pineda, J.R. Rapid differentiation of isobaric and positional isomers of structurally related glycosides from Phytolacca bogotensis. Rapid Commun. Mass Spectrom., 2009, 23(13), 3361-3371.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.13 , pp. 3361-3371
    • Montoya, G.1    Arango, G.J.2    Ramírez-Pineda, J.R.3
  • 45
    • 66149167199 scopus 로고    scopus 로고
    • Differentiation of configurations of the phenylbutenoid dimer derivatives from Zingiber cassumunar by tandem mass spectrometry
    • Chen, J.J.; Lu, Y.B.; Lin, L.; Sun, Z.; Sun, C.R.; Pan, Y.J. Differentiation of configurations of the phenylbutenoid dimer derivatives from Zingiber cassumunar by tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(11), 1654-1658.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.11 , pp. 1654-1658
    • Chen, J.J.1    Lu, Y.B.2    Lin, L.3    Sun, Z.4    Sun, C.R.5    Pan, Y.J.6
  • 46
    • 66149186746 scopus 로고    scopus 로고
    • Structural characterization and identification of C19- and C20-diterpenoid alkaloids in roots of Aconitum carmichaeli by rapid-resolution liquid chromatography coupled with time-of-flight mass spectrometry
    • Hu, R.; Zhao, J.; Qi, L.W.; Li, P.; Jing, S.L.; Li, H.J. Structural characterization and identification of C19- and C20-diterpenoid alkaloids in roots of Aconitum carmichaeli by rapid-resolution liquid chromatography coupled with time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(11), 1619-1635.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.11 , pp. 1619-1635
    • Hu, R.1    Zhao, J.2    Qi, L.W.3    Li, P.4    Jing, S.L.5    Li, H.J.6
  • 47
    • 78650784908 scopus 로고    scopus 로고
    • Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentation
    • van der Hooft, J.J,; Vervoort, J.; Bino, R.J.; Beekwilder, J.; de Vos, R.C. Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentation. Anal. Chem., 2011, 83(1), 409-416.
    • (2011) Anal. Chem. , vol.83 , Issue.1 , pp. 409-416
    • Van Der Hooft, J.J.1    Vervoort, J.2    Bino, R.J.3    Beekwilder, J.4    De Vos, R.C.5
  • 48
    • 70349808430 scopus 로고    scopus 로고
    • Advances in Nutrigenomics research: Novel and future analytical approaches to investigate the biological activity of natural compounds and food functions
    • García-Cañas, V.; Simó, C.; León, C.; Cifuentes, A. Advances in Nutrigenomics research: Novel and future analytical approaches to investigate the biological activity of natural compounds and food functions. J. Pharm. Biomed. Anal., 2010, 51(2), 290-304.
    • (2010) J. Pharm. Biomed. Anal. , vol.51 , Issue.2 , pp. 290-304
    • García-Cañas, V.1    Simó, C.2    León, C.3    Cifuentes, A.4
  • 49
    • 70349967669 scopus 로고    scopus 로고
    • Recent trends in the advanced analysis of bioactive fatty acids
    • Ruiz-Rodriguez, A.; Reglero, G.; Ibañez. E. Recent trends in the advanced analysis of bioactive fatty acids. J. Pharm. Biomed. Anal., 2010, 51(2), 305-326.
    • (2010) J. Pharm. Biomed. Anal. , vol.51 , Issue.2 , pp. 305-326
    • Ruiz-Rodriguez, A.1    Reglero, G.2    Ibañez., E.3
  • 51
    • 60349126812 scopus 로고    scopus 로고
    • Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice)
    • Zhang, Q.Y.; Ye, M. Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice). J. Chromatogr. A, 2009, 1216(11), 1954-1969.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 1954-1969
    • Zhang, Q.Y.1    Ye, M.2
  • 52
    • 60349096606 scopus 로고    scopus 로고
    • Analysis of chemical constituents in Cistanche species
    • Jiang, Y.; Tu, P.F. Analysis of chemical constituents in Cistanche species. J. Chromatogr. A, 2009, 1216(11), 1970-1979.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 1970-1979
    • Jiang, Y.1    Tu, P.F.2
  • 53
    • 60349120689 scopus 로고    scopus 로고
    • Analysis of Schisandra chinensis and Schisandra sphenanthera
    • Lu, Y.; Chen, D.F. Analysis of Schisandra chinensis and Schisandra sphenanthera. J. Chromatogr. A, 2009, 1216(11), 1980-1990.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 1980-1990
    • Lu, Y.1    Chen, D.F.2
  • 54
    • 60449117044 scopus 로고    scopus 로고
    • The analysis of Radix Angelicae Sinensis (Danggui)
    • Yi, L.Z.; Liang, Y.Z.; Wu, H.; Yuan. D.L.; The analysis of Radix Angelicae Sinensis (Danggui). J. Chromatogr. A, 2009, 1216(11), 1991-2001.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 1991-2001
    • Yi, L.Z.1    Liang, Y.Z.2    Wu, H.3    Yuan, D.L.4
  • 55
    • 60349092143 scopus 로고    scopus 로고
    • Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals
    • van Beek, T.A.; Montoro, P. Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals. J. Chromatogr. A, 2009, 1216(11), 2002-2032.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2002-2032
    • Van Beek, T.A.1    Montoro, P.2
  • 56
    • 60349130373 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis in quality control of traditional Chinese medicines
    • Liang, X.M.; Jin, Y.; Wang, Y.P.; Jin, G.W.; Fu, Q.; Xiao. Y.S. Qualitative and quantitative analysis in quality control of traditional Chinese medicines. J. Chromatogr. A, 2009, 1216(11), 2033-2044.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2033-2044
    • Liang, X.M.1    Jin, Y.2    Wang, Y.P.3    Jin, G.W.4    Fu, Q.5    Xiao., Y.S.6
  • 57
    • 70349778830 scopus 로고    scopus 로고
    • Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry
    • Zhou, J.L.; Qi, L.W.; Li, P. Herbal medicine analysis by liquid chromatography/time-of-flight mass spectrometry. J. Chromatogr. A, 2009, 1216(44), 7582-7594.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.44 , pp. 7582-7594
    • Zhou, J.L.1    Qi, L.W.2    Li, P.3
  • 58
    • 1842432471 scopus 로고    scopus 로고
    • New metabolic pathways for flavanones catalyzed by rat liver microsomes
    • Nikolic, D.; van Breemen, R.B. New metabolic pathways for flavanones catalyzed by rat liver microsomes. Drug Metab. Dispos., 2004, 32(4), 387-397.
    • (2004) Drug Metab. Dispos. , vol.32 , Issue.4 , pp. 387-397
    • Nikolic, D.1    Van Breemen, R.B.2
  • 59
    • 54349116982 scopus 로고    scopus 로고
    • Oxidative in vitro metabolism of liquiritigenin, a bioactive compound isolated from the Chinese herbal selective estrogen β-receptor agonist MF101
    • Kupfer, R.; Swanson, L.; Chow, S.; Staub, R.E.; Zhang, Y.L.; Cohen, I.; Christians, U. Oxidative in vitro metabolism of liquiritigenin, a bioactive compound isolated from the Chinese herbal selective estrogen β-receptor agonist MF101. Drug Metab. Dispos., 2008, 36(11), 2261-2269.
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.11 , pp. 2261-2269
    • Kupfer, R.1    Swanson, L.2    Chow, S.3    Staub, R.E.4    Zhang, Y.L.5    Cohen, I.6    Christians, U.7
  • 61
    • 53449087260 scopus 로고    scopus 로고
    • Aspalathin a flavonoid in Aspalathus linearis (rooibos), is absorbed by pig intestine as a C-glycoside
    • Kreuz, S.; Joubert, E.; Waldmann, K.H.; Ternes, W. Aspalathin, a flavonoid in Aspalathus linearis (rooibos), is absorbed by pig intestine as a C-glycoside. Nutr. Res., 2008, 28(10), 690-701.
    • (2008) Nutr. Res. , vol.28 , Issue.10 , pp. 690-701
    • Kreuz, S.1    Joubert, E.2    Waldmann, K.H.3    Ternes, W.4
  • 63
    • 67349174983 scopus 로고    scopus 로고
    • Microsomal metabolism of calycosin, formononetin and drug-drug interactions by dynamic microdialysis sampling and HPLC-DAD-MS analysis
    • Wen, X.D.; Qi, L.W.; Li, B.; Li, P.; Yi, L.; Wang, Y.Q.; Liu, E.H.; Yang, X.L. Microsomal metabolism of calycosin, formononetin and drug-drug interactions by dynamic microdialysis sampling and HPLC-DAD-MS analysis. J. Pharm. Biomed. Anal., 2009, 50(1), 100-105.
    • (2009) J. Pharm. Biomed. Anal. , vol.50 , Issue.1 , pp. 100-105
    • Wen, X.D.1    Qi, L.W.2    Li, B.3    Li, P.4    Yi, L.5    Wang, Y.Q.6    Liu, E.H.7    Yang, X.L.8
  • 64
    • 77953362502 scopus 로고    scopus 로고
    • Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry
    • Jirásko, R,; Holčapek, M.; Vrublová, E.; Ulrichová, J.; Šimánek. V. Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry. J. Chromatogr. A, 2010, 1217(25), 4100-4108.
    • (2010) J. Chromatogr. A , vol.1217 , Issue.25 , pp. 4100-4108
    • Jirásko, R.1    Holčapek, M.2    Vrublová, E.3    Ulrichová, J.4    Šimánek, V.5
  • 65
    • 74349128354 scopus 로고    scopus 로고
    • Metabolites of puerarin identified by liquid chromatography tandem mass spectrometry: Similar metabolic profiles in liver and intestine of rats
    • Luo, C.F.; Yuan, M.; Chen, M.S.; Liu, S.M.; Ji, H. Metabolites of puerarin identified by liquid chromatography tandem mass spectrometry: Similar metabolic profiles in liver and intestine of rats. J. Chromatogr. B, 2010, 878(3-4), 363-370.
    • (2010) J. Chromatogr. B , vol.878 , Issue.3-4 , pp. 363-370
    • Luo, C.F.1    Yuan, M.2    Chen, M.S.3    Liu, S.M.4    Ji, H.5
  • 66
    • 77950921332 scopus 로고    scopus 로고
    • Liquid chromatography- tandem mass spectrometry analysis of metabolites in rats after administration of prenylflavonoids from Epimediums
    • Zhao, H.Y.; Fan, M.S.; Fan, L.; Sun, J.H.; Guo, D.A. Liquid chromatography- tandem mass spectrometry analysis of metabolites in rats after administration of prenylflavonoids from Epimediums. J. Chromatogr. B, 2010, 878(15-16), 1113-1124.
    • (2010) J. Chromatogr. B , vol.878 , Issue.15-16 , pp. 1113-1124
    • Zhao, H.Y.1    Fan, M.S.2    Fan, L.3    Sun, J.H.4    Guo, D.A.5
  • 67
    • 33645822532 scopus 로고    scopus 로고
    • Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450
    • Ueng, Y.F.; Don, M.J.; Jan, W.C.; Wang, S.Y.; Ho, L.K.; Chen, C.F. Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450. Drug Metab. Dispos., 2006, 34(5), 821-827.
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.5 , pp. 821-827
    • Ueng, Y.F.1    Don, M.J.2    Jan, W.C.3    Wang, S.Y.4    Ho, L.K.5    Chen, C.F.6
  • 68
    • 67650002130 scopus 로고    scopus 로고
    • Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile
    • Wang, Y.Y.; Zhong, D.F.; Chen, X.Y.; Zheng, J. Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile. Chem. Res. Toxicol., 2009, 22(5), 824-834.
    • (2009) Chem. Res. Toxicol. , vol.22 , Issue.5 , pp. 824-834
    • Wang, Y.Y.1    Zhong, D.F.2    Chen, X.Y.3    Zheng, J.4
  • 69
    • 38149117001 scopus 로고    scopus 로고
    • Liquid chromatographyelectrospray ionization ion trap mass spectrometry for analysis of in vivo and in vitro metabolites of scopolamine in rats
    • Chen, H.X.; Chen, Y.; Du, P.; Han, F.M. Liquid chromatographyelectrospray ionization ion trap mass spectrometry for analysis of in vivo and in vitro metabolites of scopolamine in rats. J. Chromatogr. Sci., 2008, 46(1), 74-80.
    • (2008) J. Chromatogr. Sci. , vol.46 , Issue.1 , pp. 74-80
    • Chen, H.X.1    Chen, Y.2    Du, P.3    Han, F.M.4
  • 70
    • 77957113225 scopus 로고    scopus 로고
    • Metabolism of decentrine: Identification of the phase i and phase II metabolites in miniature pig urine
    • Lai, Y.C.; Kuo, T.F.; Chen, C.K.; Tsai, H.J.; Lee, S.S. Metabolism of decentrine: Identification of the phase I and phase II metabolites in miniature pig urine. Drug Metab. Dispos., 2010, 38(10), 1714-1722.
    • (2010) Drug Metab. Dispos. , vol.38 , Issue.10 , pp. 1714-1722
    • Lai, Y.C.1    Kuo, T.F.2    Chen, C.K.3    Tsai, H.J.4    Lee, S.S.5
  • 71
    • 77950863483 scopus 로고    scopus 로고
    • Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy
    • Chen, J.Z.; Chou, G.X.; Wang, C.H.; Yang, L.; Bligh, S.W.A.; Wang, Z.T. Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy. J. Pharm. Biomed. Anal., 2010, 52(5), 687-693.
    • (2010) J. Pharm. Biomed. Anal. , vol.52 , Issue.5 , pp. 687-693
    • Chen, J.Z.1    Chou, G.X.2    Wang, C.H.3    Yang, L.4    Bligh, S.W.A.5    Wang, Z.T.6
  • 72
    • 70349303184 scopus 로고    scopus 로고
    • Characterization of metabolites of worenine in rat biological samples using liquid chromatographytandem mass spectrometry
    • Chen, H.X.; Huang, J.L.; Li, J. Characterization of metabolites of worenine in rat biological samples using liquid chromatographytandem mass spectrometry. J. Pharm. Biomed. Anal., 2010, 51(1), 236-243.
    • (2010) J. Pharm. Biomed. Anal. , vol.51 , Issue.1 , pp. 236-243
    • Chen, H.X.1    Huang, J.L.2    Li, J.3
  • 73
    • 0345126123 scopus 로고
    • The chemical structure and the mutagenicity of emodin metabolites
    • Morooka, N.; Nakano, S.; Itoi, N.; Ueno, Y. The Chemical Structure and the Mutagenicity of Emodin Metabolites. Agric. Biol. Chem. 1990, 54(5), 1247-1252.
    • (1990) Agric. Biol. Chem. , vol.54 , Issue.5 , pp. 1247-1252
    • Morooka, N.1    Nakano, S.2    Itoi, N.3    Ueno, Y.4
  • 75
    • 14844350470 scopus 로고    scopus 로고
    • Metabolism of 1,8-cineole by human cytochrome P450 enzymes: Identification of a new hydroxylated metabolite
    • Duisken, M.; Sandner, F.; Blfmeke, B.; Hollender, J. Metabolism of 1,8-cineole by human cytochrome P450 enzymes: Identification of a new hydroxylated metabolite. Biochim. Biophys. Acta, 2005, 1722(3), 304-311.
    • (2005) Biochim. Biophys. Acta , vol.1722 , Issue.3 , pp. 304-311
    • Duisken, M.1    Sandner, F.2    Blfmeke, B.3    Hollender, J.4
  • 77
    • 77950859731 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry-based structural analysis of soyasaponin Ab metabolites by human fecal microflora
    • Chang, S.Y.; Han, M.J.; Joh, E.H.; Kim, D.H. Liquid chromatography/mass spectrometry-based structural analysis of soyasaponin Ab metabolites by human fecal microflora. J. Pharm. Biomed. Anal., 2010, 52(5), 752-756.
    • (2010) J. Pharm. Biomed. Anal. , vol.52 , Issue.5 , pp. 752-756
    • Chang, S.Y.1    Han, M.J.2    Joh, E.H.3    Kim, D.H.4
  • 78
    • 67650391579 scopus 로고    scopus 로고
    • Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange
    • Liu, Z.H.; Chen, J.; Yu, L.S.; Jiang, H.D.; Yao, T.W.; Zeng, S. Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange. Rapid Commun. Mass Spectrom., 2009, 23(13), 1899-1906.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.13 , pp. 1899-1906
    • Liu, Z.H.1    Chen, J.2    Yu, L.S.3    Jiang, H.D.4    Yao, T.W.5    Zeng, S.6
  • 79
    • 25444434647 scopus 로고    scopus 로고
    • Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice
    • Asai, A.; Nakano, T.; Takahashi, M.; Nagao, A. Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice. J. Agric. Food Chem., 2005, 53(18), 7302-7306.
    • (2005) J. Agric. Food Chem. , vol.53 , Issue.18 , pp. 7302-7306
    • Asai, A.1    Nakano, T.2    Takahashi, M.3    Nagao, A.4
  • 80
    • 67650802353 scopus 로고    scopus 로고
    • Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: Identification of biomarkers of coffee consumption
    • Stalmach, A.; Mullen, W.; Barron, D.; Uchida, K.; Yokota, T.; Cavin, C.; Steiling, H.; Williamson, G.; Crozier, A. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Metab. Dispos., 2009, 37(8), 1749-1758.
    • (2009) Drug Metab. Dispos. , vol.37 , Issue.8 , pp. 1749-1758
    • Stalmach, A.1    Mullen, W.2    Barron, D.3    Uchida, K.4    Yokota, T.5    Cavin, C.6    Steiling, H.7    Williamson, G.8    Crozier, A.9
  • 81
    • 39149093653 scopus 로고    scopus 로고
    • Investigation of the metabolic fate of dihydrocaffeic acid
    • Poquet, L.; Clifford, M.N.; Williamson, G. Investigation of the metabolic fate of dihydrocaffeic acid. Biochem. Pharmacol., 2008, 75 (5), 1218-1229.
    • (2008) Biochem. Pharmacol. , vol.75 , Issue.5 , pp. 1218-1229
    • Poquet, L.1    Clifford, M.N.2    Williamson, G.3
  • 82
    • 63449114794 scopus 로고    scopus 로고
    • Identification and fragmentation pathways of caffeine metabolites in urine samples via liquid chromatography with positive electrospray ionization coupled to a hybrid quadrupole linear ion trap (LTQ) and Fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry
    • Bianco, G.; Abate, S.; Labella, C.; Cataldi, T.R. Identification and fragmentation pathways of caffeine metabolites in urine samples via liquid chromatography with positive electrospray ionization coupled to a hybrid quadrupole linear ion trap (LTQ) and Fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(7), 1065-1074.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.7 , pp. 1065-1074
    • Bianco, G.1    Abate, S.2    Labella, C.3    Cataldi, T.R.4
  • 83
    • 60349098256 scopus 로고    scopus 로고
    • Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry
    • Lei, X.Y.; Kong, L.; Zou, H.F.; Ma, H.; Yang, L. Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry. J. Chromatogr. A, 2009, 1216(11), 2179-2184.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2179-2184
    • Lei, X.Y.1    Kong, L.2    Zou, H.F.3    Ma, H.4    Yang, L.5
  • 84
    • 77954175046 scopus 로고    scopus 로고
    • Qualitative and quantitative determination of complicated herbal components by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a relative exposure approach to herbal pharmacokinetics independent of standards
    • Liang, Y.; Hao, H.P.; Kang, A.; Xie, L.; Xie, T.; Zheng, X.; Dai, C.; Wan, L.R.; Sheng, L.S.; Wang, G.J. Qualitative and quantitative determination of complicated herbal components by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a relative exposure approach to herbal pharmacokinetics independent of standards. J. Chromatogr. A, 2010, 1217(30), 4971-4979.
    • (2010) J. Chromatogr. A , vol.1217 , Issue.30 , pp. 4971-4979
    • Liang, Y.1    Hao, H.P.2    Kang, A.3    Xie, L.4    Xie, T.5    Zheng, X.6    Dai, C.7    Wan, L.R.8    Sheng, L.S.9    Wang, G.J.10
  • 85
    • 77955925853 scopus 로고    scopus 로고
    • Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS)
    • Zhang, W.; Saif, M.W.; Dutschman, G.E.; Li, X.; Lam, W.; Bussom, S.; Jiang, Z.L.; Ye, M.; Chu, E.; Cheng, Y.C. Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS). J. Chromatogr. A, 2010, 1217(37), 5785-5793.
    • (2010) J. Chromatogr. A , vol.1217 , Issue.37 , pp. 5785-5793
    • Zhang, W.1    Saif, M.W.2    Dutschman, G.E.3    Li, X.4    Lam, W.5    Bussom, S.6    Jiang, Z.L.7    Ye, M.8    Chu, E.9    Cheng, Y.C.10
  • 86
    • 77957858384 scopus 로고    scopus 로고
    • In vivo metabolism study of rhubarb decoction in rat using highperformance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples
    • Song, R.; Xu, L.; Xu, F.G.; Li, Z.; Dong, H.J.; Tian, Y.; Zhang, Z.J. In vivo metabolism study of rhubarb decoction in rat using highperformance liquid chromatography with UV photodiode-array and mass-spectrometric detection: A strategy for systematic analysis of metabolites from traditional Chinese medicines in biological samples. J. Chromatogr. A, 2010, 1217(45), 7144-7152.
    • (2010) J. Chromatogr. A , vol.1217 , Issue.45 , pp. 7144-7152
    • Song, R.1    Xu, L.2    Xu, F.G.3    Li, Z.4    Dong, H.J.5    Tian, Y.6    Zhang, Z.J.7
  • 87
    • 70849088935 scopus 로고    scopus 로고
    • Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass spectrometry
    • Suárez, M.; Romero, M.P.; Macià, A.; Valls, R.M.; Fernández, S.; Solà, R.; Motilva. M.J.; Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 2009, 877(32), 4097-4106.
    • (2009) J. Chromatogr. B , vol.877 , Issue.32 , pp. 4097-4106
    • Suárez, M.1    Romero, M.P.2    MacIà, A.3    Valls, R.M.4    Fernández, S.5    Solà, R.6    Motilva, M.J.7
  • 88
    • 74049146364 scopus 로고    scopus 로고
    • Ultra-performance liquid chromatography-tandem mass spectrometry analysis of the bioactive components and their metabolites of Shaofu Zhuyu decoction active extract in rat plasma
    • Su, S.L.; Guo, J.M.; Duan, J.A.; Wang, T.J.; Qian, D.W.; Shang, E.X.; Tang, Y.P. Ultra-performance liquid chromatography-tandem mass spectrometry analysis of the bioactive components and their metabolites of Shaofu Zhuyu decoction active extract in rat plasma. J. Chromatogr. B, 2010, 878(3-4), 355-362.
    • (2010) J. Chromatogr. B , vol.878 , Issue.3-4 , pp. 355-362
    • Su, S.L.1    Guo, J.M.2    Duan, J.A.3    Wang, T.J.4    Qian, D.W.5    Shang, E.X.6    Tang, Y.P.7
  • 89
    • 77957320560 scopus 로고    scopus 로고
    • UPLC-QTOF/MS-based screening and identification of the constituents and their metabolites in rat plasma and urine after oral administration of Glechoma longituba extract
    • Ni, S.M.; Qian, D.W.; Duan, J.A.; Guo, J.M.; Shang, E.X.; Shu, Y.; Xue, C.F. UPLC-QTOF/MS-based screening and identification of the constituents and their metabolites in rat plasma and urine after oral administration of Glechoma longituba extract. J. Chromatogr. B, 2010, 878(28), 2741-2750.
    • (2010) J. Chromatogr. B , vol.878 , Issue.28 , pp. 2741-2750
    • Ni, S.M.1    Qian, D.W.2    Duan, J.A.3    Guo, J.M.4    Shang, E.X.5    Shu, Y.6    Xue, C.F.7
  • 90
    • 77954865201 scopus 로고    scopus 로고
    • Analysis of the bioactive constituents of ChanSu in rat plasma by high performance liquid chromatography with mass spectrometric detection
    • Xia, X.L.; Jin, H.Z.; Yan, S.K.; Zhang, W.D. Analysis of the bioactive constituents of ChanSu in rat plasma by high performance liquid chromatography with mass spectrometric detection. J. Pharm. Biomed. Anal., 2010, 53(3), 646-654.
    • (2010) J. Pharm. Biomed. Anal. , vol.53 , Issue.3 , pp. 646-654
    • Xia, X.L.1    Jin, H.Z.2    Yan, S.K.3    Zhang, W.D.4
  • 91
    • 74249094507 scopus 로고    scopus 로고
    • Characterization of the constituents in rat biological fluids after oral administration of Fufang Danshen tablets by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry
    • Lv, Y.H.; Zhang, X.; Liang, X.; Liu, X.R.; Dai, W.X.; Yan, S.K.; Zhang, W.D. Characterization of the constituents in rat biological fluids after oral administration of Fufang Danshen tablets by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry. J. Pharm. Biomed. Anal., 2010, 52(1), 155-159.
    • (2010) J. Pharm. Biomed. Anal. , vol.52 , Issue.1 , pp. 155-159
    • Lv, Y.H.1    Zhang, X.2    Liang, X.3    Liu, X.R.4    Dai, W.X.5    Yan, S.K.6    Zhang, W.D.7
  • 92
    • 77952910575 scopus 로고    scopus 로고
    • Screening and analysis of the multiple absorbed bioactive components and metabolites in rat plasma after oral administration of Jitai tablets by high-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry
    • Wang, S.P.; Liu, L.; Wang, L.L.; Jiang, P.; Zhang, J.Q.; Zhang, W.D.; Liu, R.H. Screening and analysis of the multiple absorbed bioactive components and metabolites in rat plasma after oral administration of Jitai tablets by high-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2010, 24(11), 1641-1652.
    • (2010) Rapid Commun. Mass Spectrom. , vol.24 , Issue.11 , pp. 1641-1652
    • Wang, S.P.1    Liu, L.2    Wang, L.L.3    Jiang, P.4    Zhang, J.Q.5    Zhang, W.D.6    Liu, R.H.7
  • 93
    • 75649131148 scopus 로고    scopus 로고
    • Fast and automated characterization of major constituents in rat biofluid after oral administration of Abelmoschus manihot extract using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and MetaboLynx
    • Guo, J.M.; Shang, E.X.; Duan, J.A.; Tang, Y.P.; Qian, D.W.; Su, S.L. Fast and automated characterization of major constituents in rat biofluid after oral administration of Abelmoschus manihot extract using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and MetaboLynx. Rapid Commun. Mass Spectrom., 2010, 24(4), 443-453.
    • (2010) Rapid Commun. Mass Spectrom. , vol.24 , Issue.4 , pp. 443-453
    • Guo, J.M.1    Shang, E.X.2    Duan, J.A.3    Tang, Y.P.4    Qian, D.W.5    Su, S.L.6
  • 94
    • 74249102902 scopus 로고    scopus 로고
    • Analysis of phenolic and triterpenoid compounds in licorice and rat plasma by highperformance liquid chromatography diode-array detection, time-offlight mass spectrometry and quadrupole ion trap mass spectrometry
    • Tan, G.G.; Zhu, Z.Y.; Zhang, H.; Zhao, L.; Liu, Y.; Dong, X.; Lou, Z.Y.; Zhang, G.Q.; Chai, Y.F. Analysis of phenolic and triterpenoid compounds in licorice and rat plasma by highperformance liquid chromatography diode-array detection, time-offlight mass spectrometry and quadrupole ion trap mass spectrometry. Rapid Commun. Mass Spectrom., 2010, 24(2), 209-218.
    • (2010) Rapid Commun. Mass Spectrom. , vol.24 , Issue.2 , pp. 209-218
    • Tan, G.G.1    Zhu, Z.Y.2    Zhang, H.3    Zhao, L.4    Liu, Y.5    Dong, X.6    Lou, Z.Y.7    Zhang, G.Q.8    Chai, Y.F.9
  • 95
    • 64149095083 scopus 로고    scopus 로고
    • Analysis of lignans in Schisandra chinensis and rat plasma by high-performance liquid chromatography diodearray detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry
    • Lou, Z.Y.; Zhang, H.; Gong, C.G.; Zhu, Z.Y.; Zhao, L.; Xu, Y.J.; Wang, B.; Zhang, G.Q. Analysis of lignans in Schisandra chinensis and rat plasma by high-performance liquid chromatography diodearray detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(6), 831-842.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.6 , pp. 831-842
    • Lou, Z.Y.1    Zhang, H.2    Gong, C.G.3    Zhu, Z.Y.4    Zhao, L.5    Xu, Y.J.6    Wang, B.7    Zhang, G.Q.8
  • 96
    • 77957164557 scopus 로고    scopus 로고
    • Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: Gender-related difference in metabolism of schisandra lignans in rats
    • Liang, Y.; Hao, H.P.; Xie, L.; Kang, A.; Xie, T.; Zheng, X.; Dai, C.; Hao, K.; Sheng, L.S.; Wang, G.J. Development of a Systematic Approach to Identify Metabolites for Herbal Homologs Based on Liquid Chromatography Hybrid Ion Trap Time-of-Flight Mass Spectrometry: Gender-Related Difference in Metabolism of Schisandra Lignans in Rats. Drug Metab. Dispos., 2010, 38(10), 1747-1759.
    • (2010) Drug Metab. Dispos. , vol.38 , Issue.10 , pp. 1747-1759
    • Liang, Y.1    Hao, H.P.2    Xie, L.3    Kang, A.4    Xie, T.5    Zheng, X.6    Dai, C.7    Hao, K.8    Sheng, L.S.9    Wang, G.J.10
  • 97
    • 78049356063 scopus 로고    scopus 로고
    • Profiling of the compounds absorbed in human plasma and urine after oral administration of a traditional japanese (kampo) medicine, daikenchuto
    • Iwabu, J.; Watanabe, J.; Hirakura, k.; Ozaki, Y.; Hanazaki, K. Profiling of the Compounds Absorbed in Human Plasma and Urine after Oral Administration of a Traditional Japanese (Kampo) Medicine, Daikenchuto. Drug Metab. Dispos., 2010, 38(10), 2040-2048.
    • (2010) Drug Metab. Dispos. , vol.38 , Issue.10 , pp. 2040-2048
    • Iwabu, J.1    Watanabe, J.2    Hirakura, K.3    Ozaki, Y.4    Hanazaki, K.5
  • 98
    • 67650345449 scopus 로고    scopus 로고
    • Identification of metabolites of danggui buxue tang in rat urine by liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry
    • Li, C.Y.; Qi, L.W.; Li, P.; Wen, X.D.; Zhu, Y.F.; Liu, E.H.; Gong, Z.; Yang, X.L.; Ren, M.T.; Li, Y.J.; Ge, X.X. Identification of metabolites of Danggui Buxue Tang in rat urine by liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(13), 1977-1988.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.13 , pp. 1977-1988
    • Li, C.Y.1    Qi, L.W.2    Li, P.3    Wen, X.D.4    Zhu, Y.F.5    Liu, E.H.6    Gong, Z.7    Yang, X.L.8    Ren, M.T.9    Li, Y.J.10    Ge, X.X.11
  • 99
    • 33746093547 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration
    • Chen, X.Y.; Cui, L.; Duan, X.T.; Ma, B.; Zhong, D.F. Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration. Drug Metab. Dispos., 2006, 34(8), 1345-1352.
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.8 , pp. 1345-1352
    • Chen, X.Y.1    Cui, L.2    Duan, X.T.3    Ma, B.4    Zhong, D.F.5
  • 100
    • 76149098187 scopus 로고    scopus 로고
    • Isolation and identification of urinary metabolites of kakkalide in rats
    • Bai, X.; Xie, Y.Y.; Liu, J.; Qu, J.L.; Kano, Y.; Yuan, D. Isolation and identification of urinary metabolites of kakkalide in rats. Drug Metab. Dispos., 2010, 38(2), 281-286.
    • (2010) Drug Metab. Dispos. , vol.38 , Issue.2 , pp. 281-286
    • Bai, X.1    Xie, Y.Y.2    Liu, J.3    Qu, J.L.4    Kano, Y.5    Yuan, D.6
  • 101
    • 59649109539 scopus 로고    scopus 로고
    • Metabolism of echinacoside, a good antioxidant, in rats: Isolation and identification of its biliary metabolites
    • Jia, C.Q.; Shi, H.M.; Jin, W.; Zhang, K.; Jiang, Y.; Zhao, M.B.; Tu, P.F. Metabolism of echinacoside, a good antioxidant, in rats: Isolation and identification of its biliary metabolites. Drug Metab. Dispos., 2009, 37(2), 431-438.
    • (2009) Drug Metab. Dispos. , vol.37 , Issue.2 , pp. 431-438
    • Jia, C.Q.1    Shi, H.M.2    Jin, W.3    Zhang, K.4    Jiang, Y.5    Zhao, M.B.6    Tu, P.F.7
  • 102
    • 0042026296 scopus 로고    scopus 로고
    • Identification of a rare sulfonic acid metabolite of andrographolide in rats
    • He, X.J.; Li, J.K.; Gao, H.; Qiu, F.; Hu, K.; Cui, X.M.; Yao, X.S. Identification of a rare sulfonic acid metabolite of andrographolide in rats. Drug Metab. Dispos., 2003; 31(8): 983-985.
    • (2003) Drug Metab. Dispos. , vol.31 , Issue.8 , pp. 983-985
    • He, X.J.1    Li, J.K.2    Gao, H.3    Qiu, F.4    Hu, K.5    Cui, X.M.6    Yao, X.S.7
  • 103
    • 15344346646 scopus 로고    scopus 로고
    • Four new andrographolide metabolites in human urine
    • Cui, L.; Qiu, F.; Wang, N.L.; Yao, X.S. Four new andrographolide metabolites in human urine. Chem. Pharm. Bull., 2004; 52(6), 772-775.
    • (2004) Chem. Pharm. Bull. , vol.52 , Issue.6 , pp. 772-775
    • Cui, L.1    Qiu, F.2    Wang, N.L.3    Yao, X.S.4
  • 104
    • 15344339360 scopus 로고    scopus 로고
    • Isolation and identification of seven glucuronide conjugates of andrographolide in human urine
    • Cui, L.; Qiu, F.; Yao, X.S. Isolation and identification of seven glucuronide conjugates of andrographolide in human urine. Drug Metab. Dispos., 2005, 33(4), 555-562.
    • (2005) Drug Metab. Dispos. , vol.33 , Issue.4 , pp. 555-562
    • Cui, L.1    Qiu, F.2    Yao, X.S.3
  • 105
    • 54349118402 scopus 로고    scopus 로고
    • Isolation and identification of urinary metabolites of berberine in rats and humans
    • Qiu, F.; Zhu, Z.Y.; Kang, N.; Piao, S.J.; Qin, G.Y.; Yao, X.S. Isolation and identification of urinary metabolites of berberine in rats and humans. Drug Metab. Dispos., 2008, 36(11), 2159-2165.
    • (2008) Drug Metab. Dispos. , vol.36 , Issue.11 , pp. 2159-2165
    • Qiu, F.1    Zhu, Z.Y.2    Kang, N.3    Piao, S.J.4    Qin, G.Y.5    Yao, X.S.6
  • 106
    • 34548071764 scopus 로고    scopus 로고
    • Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats
    • Zeng, Y.C.; Qiu, F.; Liu, Y.; Qu, G.X.; Yao, X.S. Isolation and identification of phase 1 metabolites of demethoxycurcumin in rats. Drug Metab. Dispos., 2007, 35(9), 1564-1573.
    • (2007) Drug Metab. Dispos. , vol.35 , Issue.9 , pp. 1564-1573
    • Zeng, Y.C.1    Qiu, F.2    Liu, Y.3    Qu, G.X.4    Yao, X.S.5
  • 107
    • 75849155201 scopus 로고    scopus 로고
    • Study on the stereoselective excretion of tetrahydropalmatine enantiomers in rats and identification of in vivo metabolites by liquid chromatography-tandem mass spectrometry
    • Hong, Z.Y.; Wen, J.; Zhang, Q.L.; Fan, G.R.; Chai, Y.F.; Wu, Y.T. Study on the stereoselective excretion of tetrahydropalmatine enantiomers in rats and identification of in vivo metabolites by liquid chromatography-tandem mass spectrometry. Chirality, 2010, 22(3), 355-360.
    • (2010) Chirality , vol.22 , Issue.3 , pp. 355-360
    • Hong, Z.Y.1    Wen, J.2    Zhang, Q.L.3    Fan, G.R.4    Chai, Y.F.5    Wu, Y.T.6
  • 108
    • 33751511999 scopus 로고    scopus 로고
    • Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry
    • Zuo, F.; Nakamura, N.; Akao, T.; Hattori, M. Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metab. Dispos., 2006, 34(12), 2064-2072.
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.12 , pp. 2064-2072
    • Zuo, F.1    Nakamura, N.2    Akao, T.3    Hattori, M.4
  • 110
    • 0035370769 scopus 로고    scopus 로고
    • Identification of quercetin 3-O-β-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin
    • Moon, J.H.; Tsushida, T.; Nakahara, K.; Terao, J. Identification of quercetin 3-O-β-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin. Free Radic. Biol. Med., 2001, 30(11), 1274-1285.
    • (2001) Free Radic. Biol. Med. , vol.30 , Issue.11 , pp. 1274-1285
    • Moon, J.H.1    Tsushida, T.2    Nakahara, K.3    Terao, J.4
  • 112
    • 35348929342 scopus 로고    scopus 로고
    • Identification of a tryptanthrin metabolite in rat liver microsomes by liquid chromatography/electrospray ionization-tandem mass spectrometry
    • Lee, S.K.; Kim, G.H.; Kim, D.H.; Kim, D.H.; Jahng, Y.D.; Jeong T.C. Identification of a tryptanthrin metabolite in rat liver microsomes by liquid chromatography/electrospray ionization-tandem mass spectrometry. Biol. Pharm. Bull., 2007, 30(10), 1991-1995.
    • (2007) Biol. Pharm. Bull. , vol.30 , Issue.10 , pp. 1991-1995
    • Lee, S.K.1    Kim, G.H.2    Kim, D.H.3    Kim, D.H.4    Jahng, Y.D.5    Jeong, T.C.6
  • 113
    • 67650899278 scopus 로고    scopus 로고
    • Identification and quantification of metabolites of orally administered naringenin chalcone in rats
    • Yoshimura, M.; Sano, A.; Kamei, J.I.; Obata, A. Identification and quantification of metabolites of orally administered naringenin chalcone in rats. J. Agric. Food. Chem., 2009, 57(14), 6432-6437.
    • (2009) J. Agric. Food. Chem. , vol.57 , Issue.14 , pp. 6432-6437
    • Yoshimura, M.1    Sano, A.2    Kamei, J.I.3    Obata, A.4
  • 114
    • 0031793967 scopus 로고    scopus 로고
    • Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes
    • Mueller, S.O.; Stopper, H.; Dekant, W. Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Drug Metab. Dipos., 1998, 26(6), 540-546.
    • (1998) Drug Metab. Dipos. , vol.26 , Issue.6 , pp. 540-546
    • Mueller, S.O.1    Stopper, H.2    Dekant, W.3
  • 115
    • 8844236064 scopus 로고    scopus 로고
    • Identification of 14 quercetin phase II mono- and mixed conjugates and their formation by rat and human phase II in vitro model systems
    • van der Woude, H.; Boersma, M.G.; Vervoort, J.; Rietjens, I.M. Identification of 14 quercetin phase II mono- and mixed conjugates and their formation by rat and human phase II in vitro model systems. Chem. Res. Toxicol., 2004, 17(11), 1520-1530.
    • (2004) Chem. Res. Toxicol. , vol.17 , Issue.11 , pp. 1520-1530
    • Van Der Woude, H.1    Boersma, M.G.2    Vervoort, J.3    Rietjens, I.M.4
  • 117
    • 33947423913 scopus 로고    scopus 로고
    • Identification of a new metabolite of astilbin, 3'-O-methylastilbin, and its immunosuppressive activity against contact dermatitis
    • Guo, J.M.; Qian, F.; Li, J.X.; Xu, Q.; Chen, T. Identification of a new metabolite of astilbin, 3'-O-methylastilbin, and its immunosuppressive activity against contact dermatitis. Clin. Chem., 2007, 53(3), 465-71.
    • (2007) Clin. Chem. , vol.53 , Issue.3 , pp. 465-471
    • Guo, J.M.1    Qian, F.2    Li, J.X.3    Xu, Q.4    Chen, T.5
  • 118
    • 33748988463 scopus 로고    scopus 로고
    • Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings
    • Messina, M.; McCaskill-Stevens, W.; Lampe, J.W. Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings. J. Natl. Cancer Inst., 2006, 98(18), 1275-1284.
    • (2006) J. Natl. Cancer Inst. , vol.98 , Issue.18 , pp. 1275-1284
    • Messina, M.1    McCaskill-Stevens, W.2    Lampe, J.W.3
  • 121
    • 17844383721 scopus 로고    scopus 로고
    • Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus
    • Ye, M.; Han, J.; Tu, G.Z.; An, D.G.; Guo, D.A. Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus. J. Nat. Prod., 2005, 68(4), 626-628.
    • (2005) J. Nat. Prod. , vol.68 , Issue.4 , pp. 626-628
    • Ye, M.1    Han, J.2    Tu, G.Z.3    An, D.G.4    Guo, D.A.5
  • 126
    • 0037375173 scopus 로고    scopus 로고
    • Biotransformation of cinobufagin by cell suspension cultures of Catharanthus roseus and Platycodon grandiflorum
    • Ye, M.; Ning, L.L.; Zhan, J.X.; Guo, H.Z.; Guo, D.A. Biotransformation of cinobufagin by cell suspension cultures of Catharanthus roseus and Platycodon grandiflorum. J. Mol. Catal. B: Enzym., 2003, 22(1-2), 89-95.
    • (2003) J. Mol. Catal. B: Enzym. , vol.22 , Issue.1-2 , pp. 89-95
    • Ye, M.1    Ning, L.L.2    Zhan, J.X.3    Guo, H.Z.4    Guo, D.A.5
  • 127
    • 0037131716 scopus 로고    scopus 로고
    • Glucosylation of cinobufagin by cultured suspension cells of Catharanthus roseus
    • Ye, M.; Dai, J.G.; Guo, H.Z.; Cui, Y.J.; Guo, D.A. Glucosylation of cinobufagin by cultured suspension cells of Catharanthus roseus. Tetrahedron Lett., 2002, 43(47), 8535-8538.
    • (2002) Tetrahedron Lett. , vol.43 , Issue.47 , pp. 8535-8538
    • Ye, M.1    Dai, J.G.2    Guo, H.Z.3    Cui, Y.J.4    Guo, D.A.5
  • 129
    • 0030763576 scopus 로고    scopus 로고
    • Absorption distribution, elimination of tea polyphenols in rats
    • Chen, L.S.; Lee, M.J.; Li, H.; Yang, C.S. Absorption, distribution, elimination of tea polyphenols in rats. Drug Metab. Dispos., 1997, 25(9), 1045-1050.
    • (1997) Drug Metab. Dispos. , vol.25 , Issue.9 , pp. 1045-1050
    • Chen, L.S.1    Lee, M.J.2    Li, H.3    Yang, C.S.4
  • 132
    • 0036801990 scopus 로고    scopus 로고
    • Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3- gallate by humans: Formation of different metabolites and individual variability
    • Lee, M.J.; Maliakal, P.; Chen, L.S.; Meng, X.F.; Bondoc, F.Y.; Prabhu, S.; Lambert, G.; Mohr, S.; Yang, C.S. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3- gallate by humans: Formation of different metabolites and individual variability. Cancer Epidem. Biomarkers Prev., 2002, 11, 1025-1032.
    • (2002) Cancer Epidem. Biomarkers Prev. , vol.11 , pp. 1025-1032
    • Lee, M.J.1    Maliakal, P.2    Chen, L.S.3    Meng, X.F.4    Bondoc, F.Y.5    Prabhu, S.6    Lambert, G.7    Mohr, S.8    Yang, C.S.9
  • 133
    • 0034967897 scopus 로고    scopus 로고
    • Analysis of urinary metabolites of tea catechins by liquid chromatograph/electrospray ionization mass spectrometry
    • Li, C.; Meng, X.F.; Winnik, B.; Lee, M.J.; Lu, H.; Sheng, S.Q.; Buckley, B.; Yang, C.S. Analysis of urinary metabolites of tea catechins by liquid chromatograph/electrospray ionization mass spectrometry. Chem. Res. Toxicol., 2001, 14(6), 702-707.
    • (2001) Chem. Res. Toxicol. , vol.14 , Issue.6 , pp. 702-707
    • Li, C.1    Meng, X.F.2    Winnik, B.3    Lee, M.J.4    Lu, H.5    Sheng, S.Q.6    Buckley, B.7    Yang, C.S.8
  • 135
    • 0037403751 scopus 로고    scopus 로고
    • Enzymology ofmethylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)- epigallocatechin gallate
    • Lu, H.; Meng, X.F.; Yang, C.S. Enzymology ofmethylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)- epigallocatechin gallate. Drug Metab. Dispos., 2003, 31(5), 572-579.
    • (2003) Drug Metab. Dispos. , vol.31 , Issue.5 , pp. 572-579
    • Lu, H.1    Meng, X.F.2    Yang, C.S.3
  • 136
    • 58149354529 scopus 로고    scopus 로고
    • Structural identification of novel glucoside and glucuronide metabolites of (-)-epigallocatechin-3-gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry
    • Sang, S.M.; Yang, C.S. Structural identification of novel glucoside and glucuronide metabolites of (-)-epigallocatechin-3-gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 2008, 22(22), 3693-3699.
    • (2008) Rapid Commun. Mass Spectrom. , vol.22 , Issue.22 , pp. 3693-3699
    • Sang, S.M.1    Yang, C.S.2
  • 137
    • 0042012824 scopus 로고    scopus 로고
    • Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat
    • Kohri, T.; Suzuki, M.; Nanjo, F. Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. J. Agric. Food Chem., 2003, 51(18), 5561-5566.
    • (2003) J. Agric. Food Chem. , vol.51 , Issue.18 , pp. 5561-5566
    • Kohri, T.1    Suzuki, M.2    Nanjo, F.3
  • 139
    • 33749446855 scopus 로고    scopus 로고
    • Metabolism of green tea catechins: An overview
    • Feng, W.Y. Metabolism of green tea catechins: An overview. Curr. Drug Metab., 2006, 7(7), 755-809.
    • (2006) Curr. Drug Metab. , vol.7 , Issue.7 , pp. 755-809
    • Feng, W.Y.1
  • 140
    • 60649119124 scopus 로고    scopus 로고
    • Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen)
    • Li, Y.G.; Song, L.; Liu, M.; Hu, Z.B.; Wang, Z.T. Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen). J. Chromatogr. A, 2009, 1216(11), 1941-1953.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 1941-1953
    • Li, Y.G.1    Song, L.2    Liu, M.3    Hu, Z.B.4    Wang, Z.T.5
  • 141
    • 33748796405 scopus 로고    scopus 로고
    • Reassignment of the configuration of salvianolic acid B and establishment of its identity with lithospermic acid B
    • Watzke, A.; O'Malley, S.J.; Bergman, R.G.; Ellman, J.A. Reassignment of the configuration of salvianolic acid B and establishment of its identity with lithospermic acid B. J. Nat. Prod., 2006, 69(8), 1231-1233.
    • (2006) J. Nat. Prod. , vol.69 , Issue.8 , pp. 1231-1233
    • Watzke, A.1    O'Malley, S.J.2    Bergman, R.G.3    Ellman, J.A.4
  • 142
    • 3042634920 scopus 로고    scopus 로고
    • Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants
    • Zhang, Y.; Akao, T.; Nakamura, N.; Hattori, M.; Yang, X.W.; Duan, C.L.; Liu, J.X. Magnesium lithospermate B is excreted rapidly into rat bile mostly as methylated metabolites, which are potent antioxidants. Drug Metab. Dispos., 2004, 32(7), 752-757.
    • (2004) Drug Metab. Dispos. , vol.32 , Issue.7 , pp. 752-757
    • Zhang, Y.1    Akao, T.2    Nakamura, N.3    Hattori, M.4    Yang, X.W.5    Duan, C.L.6    Liu, J.X.7
  • 143
    • 34848814434 scopus 로고    scopus 로고
    • Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography- mass spectrometry
    • Xu, M.; Guo, H.; Han, J.; Sun, S.F.; Liu, A.H.; Wang, B.R.; Ma, X.C.; Liu, P.; Qiao, X.; Zhang, Z.C.; Guo, D.A. Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography- mass spectrometry. J. Chromatogr. B, 2007; 858(1-2), 184-198.
    • (2007) J. Chromatogr. B , vol.858 , Issue.1-2 , pp. 184-198
    • Xu, M.1    Guo, H.2    Han, J.3    Sun, S.F.4    Liu, A.H.5    Wang, B.R.6    Ma, X.C.7    Liu, P.8    Qiao, X.9    Zhang, Z.C.10    Guo, D.A.11
  • 144
    • 33846422712 scopus 로고    scopus 로고
    • Pharmacokinetics tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats
    • Li, X.C.; Yu, C.; Lu, Y.L.; Gu, Y.L.; Lu, J.; Xu, W.; Xuan, L.J.; Wang, Y.P. Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats. Drug Metab. Dispos., 2007, 35(2), 234-239.
    • (2007) Drug Metab. Dispos. , vol.35 , Issue.2 , pp. 234-239
    • Li, X.C.1    Yu, C.2    Lu, Y.L.3    Gu, Y.L.4    Lu, J.5    Xu, W.6    Xuan, L.J.7    Wang, Y.P.8
  • 145
    • 67149107346 scopus 로고    scopus 로고
    • Characterization of metabolites in rat plasma after intravenous administration of salvianolic acid A by liquid chromatography/time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry
    • Shen, Y.; Wang, X.Y.; Xu, L.H.; Liu, X.W.; Chao, R.B. Characterization of metabolites in rat plasma after intravenous administration of salvianolic acid A by liquid chromatography/time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. Rapid Commun. Mass Spectrom., 2009, 23(12), 1810-1816.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , Issue.12 , pp. 1810-1816
    • Shen, Y.1    Wang, X.Y.2    Xu, L.H.3    Liu, X.W.4    Chao, R.B.5
  • 146
    • 34548134809 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometry analysis of protocatechuic aldehyde and its phase i and II metabolites in rat
    • Xu, M.; Zhang, Z.C.; Fu, G.; Sun, S.F.; Sun, J.H.; Yang, M.; Liu, A.H.; Han, J.; Guo, D.A. Liquid chromatography-tandem mass spectrometry analysis of protocatechuic aldehyde and its phase I and II metabolites in rat. J. Chromatogr. B, 2007, 856(1-2), 100-107.
    • (2007) J. Chromatogr. B , vol.856 , Issue.1-2 , pp. 100-107
    • Xu, M.1    Zhang, Z.C.2    Fu, G.3    Sun, S.F.4    Sun, J.H.5    Yang, M.6    Liu, A.H.7    Han, J.8    Guo, D.A.9
  • 147
    • 33745771523 scopus 로고    scopus 로고
    • Characterization of metabolites of tanshinone IIA in rats by liquid chromatography/tandem mass spectrometry
    • Li, P.; Wang, G.J.; Li, J.; Hao, H.P.; Zheng, C.N. Characterization of metabolites of tanshinone IIA in rats by liquid chromatography/tandem mass spectrometry. J. Mass Spectrom., 2006, 41(5), 670-684.
    • (2006) J. Mass Spectrom. , vol.41 , Issue.5 , pp. 670-684
    • Li, P.1    Wang, G.J.2    Li, J.3    Hao, H.P.4    Zheng, C.N.5
  • 148
    • 30744472611 scopus 로고    scopus 로고
    • Identification of tanshinone IIA metabolites in rat liver microsomes by liquid chromatography- tandem mass spectrometry
    • Li, P.; Wang, G.J.; Li, J.; Hao, H.P.; Zheng, C.N. Identification of tanshinone IIA metabolites in rat liver microsomes by liquid chromatography- tandem mass spectrometry. J. Chromatogr. A, 2006, 1104(1-2), 366-369.
    • (2006) J. Chromatogr. A , vol.1104 , Issue.1-2 , pp. 366-369
    • Li, P.1    Wang, G.J.2    Li, J.3    Hao, H.P.4    Zheng, C.N.5
  • 149
    • 34249941530 scopus 로고    scopus 로고
    • Identification of tanshinones and their metabolites in rat bile after oral administartion of TTE-50, a standardized extract of Salvia miltiorrhiza by HPLC-ESI-DAD-MSn
    • Sun, J.H.; Yang, M.; Wang, X.M.; Xu, M.; Guo, D.A. Identification of tanshinones and their metabolites in rat bile after oral administartion of TTE-50, a standardized extract of Salvia miltiorrhiza by HPLC-ESI-DAD-MSn. J. Pharm. Biomed. Anal., 2007, 44(2), 564-74.
    • (2007) J. Pharm. Biomed. Anal. , vol.44 , Issue.2 , pp. 564-574
    • Sun, J.H.1    Yang, M.2    Wang, X.M.3    Xu, M.4    Guo, D.A.5
  • 150
    • 34547208680 scopus 로고    scopus 로고
    • Profiling the metabolic difference of seven tanshinones using high-performance liquid chromatography/multi-stage mass spectrometry with data-dependent acquisition
    • Sun, J.H.; Yang, M.; Han, J.; Wang, B.R.; Ma, X.C.; Xu, M.; Liu P.; Guo, D.A. Profiling the metabolic difference of seven tanshinones using high-performance liquid chromatography/multi-stage mass spectrometry with data-dependent acquisition. Rapid Commun. Mass Spectrom., 2007, 21(14), 2211-2226.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , Issue.14 , pp. 2211-2226
    • Sun, J.H.1    Yang, M.2    Han, J.3    Wang, B.R.4    Ma, X.C.5    Xu, M.6    Liu, P.7    Guo, D.A.8
  • 151
    • 53049084767 scopus 로고    scopus 로고
    • Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MSn
    • Dai, H.X.; Wang, M.M.; Li, X.R.; Wang, L.J.; Li, Y.H.; Xue, M. Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MSn. J. Pharm. Biomed. Anal., 2008, 48(3), 885-896.
    • (2008) J. Pharm. Biomed. Anal. , vol.48 , Issue.3 , pp. 885-896
    • Dai, H.X.1    Wang, M.M.2    Li, X.R.3    Wang, L.J.4    Li, Y.H.5    Xue, M.6
  • 152
    • 77950298595 scopus 로고    scopus 로고
    • Structural elucidation of metabolites of tanshinone i and its analogue dihydrotanshinone i in rats by HPLC-ESI-MSn
    • Wang, M.M.; Dai, H.X.; Li, X.R.; Li, Y.H.; Wang, L.J.; Xue, M. Structural elucidation of metabolites of tanshinone I and its analogue dihydrotanshinone I in rats by HPLC-ESI-MSn. J. Chromatogr. B, 2010, 878(13-14), 915-924.
    • (2010) J. Chromatogr. B , vol.878 , Issue.13-14 , pp. 915-924
    • Wang, M.M.1    Dai, H.X.2    Li, X.R.3    Li, Y.H.4    Wang, L.J.5    Xue, M.6
  • 153
    • 48349090750 scopus 로고    scopus 로고
    • Comparative analysis on microbial and rat metabolism of ginsenoside Rb1 by highperformance liquid chromatography coupled with tandem mass spectrometry
    • Chen, G.T.; Yang, M.; Song, Y.; Lu, Z.Q.; Zhang, J.Q.; Huang, H.L.; Guan, S.H.; Wu, L.J.; Guo, D.A. Comparative analysis on microbial and rat metabolism of ginsenoside Rb1 by highperformance liquid chromatography coupled with tandem mass spectrometry. Biomed. Chromatogr., 2008, 22(7), 779-785.
    • (2008) Biomed. Chromatogr. , vol.22 , Issue.7 , pp. 779-785
    • Chen, G.T.1    Yang, M.2    Song, Y.3    Lu, Z.Q.4    Zhang, J.Q.5    Huang, H.L.6    Guan, S.H.7    Wu, L.J.8    Guo, D.A.9
  • 154
    • 60349094657 scopus 로고    scopus 로고
    • Bioconversion of red ginseng saponins in the gastro-intestinal tract in vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry
    • Kong, H.W.; Wang, M.; Venema, K.; Maathuis, A.; van der Heijden, B.; van der Greef, J.; Xu, G.W.; Hankemeier. T. Bioconversion of red ginseng saponins in the gastro-intestinal tract in vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry. J. Chromatogr. A, 2009, 1216(11), 2195-2203.
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2195-2203
    • Kong, H.W.1    Wang, M.2    Venema, K.3    Maathuis, A.4    Van Der Heijden, B.5    Van Der Greef, J.6    Xu, G.W.7    Hankemeier, T.8
  • 155
    • 67249119760 scopus 로고    scopus 로고
    • Characterization of pharmacokinetic profiles and metabolic pathways of 20(S)-ginsenoside Rh1 in vivo and in vitro
    • Lai, L.; Hao, H.P.; Liu, Y.T.; Zheng, C.N.; Wang, Q.; Wang, G.J.; Chen, X.J. Characterization of pharmacokinetic profiles and metabolic pathways of 20(S)-ginsenoside Rh1 in vivo and in vitro. Planta Med., 2009, 75(8), 797-802.
    • (2009) Planta Med. , vol.75 , Issue.8 , pp. 797-802
    • Lai, L.1    Hao, H.P.2    Liu, Y.T.3    Zheng, C.N.4    Wang, Q.5    Wang, G.J.6    Chen, X.J.7
  • 156
    • 70350221898 scopus 로고    scopus 로고
    • In vivo metabolism study of ginsenoside Re in rat using high-performance liquid chromatography coupled with tandem mass spectrometry
    • Yang, L.; Xu, S.J.; Liu, C.J.; Su, Z.J. In vivo metabolism study of ginsenoside Re in rat using high-performance liquid chromatography coupled with tandem mass spectrometry. Anal. Bioanal. Chem., 2009, 395(5), 1441-1451.
    • (2009) Anal. Bioanal. Chem. , vol.395 , Issue.5 , pp. 1441-1451
    • Yang, L.1    Xu, S.J.2    Liu, C.J.3    Su, Z.J.4
  • 157
    • 77957236253 scopus 로고    scopus 로고
    • Microsomal cytochrome p450- mediated metabolism of protopanaxatriol ginsenosides: Metabolite profile, reaction phenotyping, and structure- metabolism relationship
    • Hao, H.P.; Lai, L.; Zheng, C.N.; Wang, Q.; Yu, G.; Zhou, X.Y.; Wu, L.; Gong, P.; Wang, G.J. Microsomal Cytochrome P450- Mediated Metabolism of Protopanaxatriol Ginsenosides: Metabolite Profile, Reaction Phenotyping, and Structure- Metabolism Relationship. Drug. Metab. Dispos., 2010, 38(10), 1731-1739;
    • (2010) Drug. Metab. Dispos. , vol.38 , Issue.10 , pp. 1731-1739
    • Hao, H.P.1    Lai, L.2    Zheng, C.N.3    Wang, Q.4    Yu, G.5    Zhou, X.Y.6    Wu, L.7    Gong, P.8    Wang, G.J.9
  • 158
    • 79951933277 scopus 로고    scopus 로고
    • Identification of 20(s)- protopanaxadiol metabolites in human liver microsomes and human heptatocytes
    • Li, L.; Chen, X.Y.; Li, D.; Zhong, D.F. Identification of 20(S)- Protopanaxadiol Metabolites in Human Liver Microsomes and Human Heptatocytes. Drug. Metab. Dispos., 2011, 39(3): 472-483
    • (2011) Drug. Metab. Dispos. , vol.39 , Issue.3 , pp. 472-483
    • Li, L.1    Chen, X.Y.2    Li, D.3    Zhong, D.F.4
  • 159
    • 78751504470 scopus 로고    scopus 로고
    • Pharmacokinetics tissue distribution, metabolism, and excretion of ginsenoside Rg1 in rats
    • Feng, L.; Wang, L.; Hu, C.J.; Jiang, X.H. Pharmacokinetics, tissue distribution, metabolism, and excretion of ginsenoside Rg1 in rats. Arch. Pharm. Res., 2010, 33(12), 1975-1984.
    • (2010) Arch. Pharm. Res. , vol.33 , Issue.12 , pp. 1975-1984
    • Feng, L.1    Wang, L.2    Hu, C.J.3    Jiang, X.H.4
  • 160
    • 79955738030 scopus 로고    scopus 로고
    • Deglycosylated ginsenosides are more potent inducers of CYP1A1, CYP1A2 and CYP3A4 expression in HepG2 cells than glycosylated ginsenosides
    • Hao, M.; Ba, Q.; Yin, J.; Li, J.Q; Zhao, Y.Q.; Wang H. Deglycosylated ginsenosides are more potent inducers of CYP1A1, CYP1A2 and CYP3A4 expression in HepG2 cells than glycosylated ginsenosides. Drug. Metab. Pharmacokinet., 2011, 26(2): 201-205
    • (2011) Drug. Metab. Pharmacokinet. , vol.26 , Issue.2 , pp. 201-205
    • Hao, M.1    Ba, Q.2    Yin, J.3    Li, J.Q.4    Zhao, Y.Q.5    Wang, H.6
  • 162
    • 70349137136 scopus 로고    scopus 로고
    • High-field asymmetric waveform ion mobility spectrometry for determining the location of in-source collisioninduced dissociation in electrospray ionization mass spectrometry
    • Xia, Y.Q.; Jemal, M. High-field asymmetric waveform ion mobility spectrometry for determining the location of in-source collisioninduced dissociation in electrospray ionization mass spectrometry. Anal. Chem., 2009, 81(18), 7839-7843.
    • (2009) Anal. Chem. , vol.81 , Issue.18 , pp. 7839-7843
    • Xia, Y.Q.1    Jemal, M.2
  • 163
    • 78049505292 scopus 로고    scopus 로고
    • Collision cross-section determination and tandem mass spectrometric analysis of isomeric carotenoids using electrospray ion mobility time-of-flight mass spectrometry
    • Dong, L.L.; Shion, H.; Davis, R.G.; Terry-Penak, B.; Castro-Perez, J.; van Breemen, R.B. Collision cross-section determination and tandem mass spectrometric analysis of isomeric carotenoids using electrospray ion mobility time-of-flight mass spectrometry. Anal. Chem., 2010, 82(1), 9014-9021.
    • (2010) Anal. Chem. , vol.82 , Issue.1 , pp. 9014-9021
    • Dong, L.L.1    Shion, H.2    Davis, R.G.3    Terry-Penak, B.4    Castro-Perez, J.5    Van Breemen, R.B.6


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