Microsomal metabolism of calycosin, formononetin and drug-drug interactions by dynamic microdialysis sampling and HPLC-DAD-MS analysis

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 1, 2009, Pages 100-105

  Wen, Xiao Dong ^a   Qi, Lian Wen ^a   Li, Bin ^a   Li, Ping ^a   Yi, Ling ^a   Wang, Ya Qiong ^a   Liu, E Hu ^a   Yang, Xiao Lin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Calycosin and formononetin; Drug drug interactions; LC DAD TOF MS; Microdialysis sampling; Microsomal metabolism

Indexed keywords

CALYCOSIN; CYTOCHROME P450; DAIDZEIN; FORMONONETIN; ISOFLAVONE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG HYDROXYLATION; DRUG IDENTIFICATION; DRUG METABOLISM; ENZYME INHIBITION; ENZYME MECHANISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MICRODIALYSIS; MICROSOME; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TIME OF FLIGHT MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; ISOFLAVONES; MASS SPECTROMETRY; MICRODIALYSIS; MICROSOMES; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 67349174983     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.03.038     Document Type: Article

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