Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 5, 2010, Pages 687-693

  Chen, Jian Zhong ^a   Chou, Gui Xin ^b,c   Wang, Chang Hong ^b   Yang, Li ^b   Bligh, S W Annie ^d   Wang, Zheng Tao ^a,b,c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Shanghai R and D Center for Standardization of Chinese Medicines   (China)

^d LONDON METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Identification; Ion trap; Metabolite; NMR; Norisoboldine

Indexed keywords

ISOQUINOLINE ALKALOID; NORISOBOLDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BILE; DRUG ISOLATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TRANSFORMATION; ELECTROSPRAY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; SULFATION; ULTRAVIOLET SPECTROSCOPY; URINALYSIS;

ALKALOIDS; ANIMALS; BILE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 77950863483     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.02.008     Document Type: Article

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