Structural elucidation of metabolites of tanshinone I and its analogue dihydrotanshinone I in rats by HPLC-ESI-MSn

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 13-14, 2010, Pages 915-924

  Wang, Mingming ^a   Dai, Haixue ^a   Li, Xiaorong ^a   Li, Yuhang ^a   Wang, Lijuan ^a   Xue, Ming ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Dihydrotanshinone I; LC ESI MSn; Metabolites; Structural elucidation; Tanshinone I

Indexed keywords

ACTIVE COMPONENTS; ANTI-INFLAMMATORIES; ANTICANCER ACTIVITIES; CHROMATOGRAPHIC RETENTION; DIHYDROTANSHINONE I; FURAN RING; HPLC-ESI MS; LC-ESI-MS; NEUTRAL LOSS; PHASE I; PHASE II; PRECURSOR IONS; SALVIA MILTIORRHIZA BUNGE; STRUCTURAL ELUCIDATION; TWO PHASE;

BIOMOLECULES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES;

METABOLISM;

DIHYDROTANSHINONE I; PLANT EXTRACT; TANSHINONE I; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOTRANSFORMATION; DEHYDROGENATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; RAT; SALVIA; SALVIA MILTIORRHIZA; SALVIA PRZEWALSKII;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROXYLATION; MALE; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHENANTHRENES; PHENANTHROLINES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

RATTUS; SALVIA MILTIORRHIZA; SALVIA PRZEWALSKII;

EID: 77950298595     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.02.014     Document Type: Article

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