Characterization of the constituents in rat biological fluids after oral administration of Fufang Danshen tablets by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 1, 2010, Pages 155-159

  Lv, Yonghai ^a   Zhang, Xi ^a   Liang, Xu ^a   Liu, Xinru ^a   Dai, Weixing ^a   Yan, Shikai ^b   Zhang, Weidong ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Active ingredients; Fufang Danshen tablets; Metabolites; Plasma; UPLC Q TOF MS; Urine

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; CORONARY VASODILATING AGENT; DANSHEXINKUN B; DRUG METABOLITE; FUFANG DANSHEN; GINSENOSIDE RC; ISOCRYPTOTANSHINONE; ISOTANSHINONE II; METHYLTANSHINONATE; PLANT MEDICINAL PRODUCT; TANSHINALDEHYDE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BORNEOLUM SYNTHETICUM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SCREENING; DRUG URINE LEVEL; HERB; LIQUID CHROMATOGRAPHY; NONHUMAN; PANAX NOTOGINSENG; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; RAT; SALVIA MILTIORRHIZA; SENSITIVITY AND SPECIFICITY; TIME OF FLIGHT MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL MARKERS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; DRUGS, CHINESE HERBAL; MALE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TABLETS;

EID: 74249094507     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.12.013     Document Type: Article

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