Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MSn

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 3, 2008, Pages 885-896

  Dai, Haixue ^a   Wang, Mingming ^a   Li, Xiaorong ^a   Wang, Lijuan ^a   Li, Yuhang ^a   Xue, Ming ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cryptotanshinone; LC DAD ESI MSn; Metabolites; Structural elucidation

Indexed keywords

CRYPTOTANSHINONE; DRUG METABOLITE; FURAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DEHYDROGENATION; DRUG HYDROXYLATION; DRUG STRUCTURE; DRUG TRANSFORMATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SALVIA MILTIORRHIZA; STRUCTURE ANALYSIS;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; HYDROXYLATION; MALE; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PHENANTHRENES; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; SALVIA MILTIORRHIZA; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 53049084767     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.07.011     Document Type: Article

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