-
1
-
-
0037390017
-
Molecular therapeutics: Is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs?
-
Arteaga CL (2003) Molecular therapeutics: is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs? Clin Cancer Res 9:1231-1232.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1231-1232
-
-
Arteaga, C.L.1
-
2
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
3
-
-
43849084078
-
Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling
-
Chouinard S, Yueh MF, Tukey RH, Giton F, Fiet J, Pelletier G, Barbier O, and Bélanger A (2008) Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. J Steroid Biochem Mol Biol 109:247-253.
-
(2008)
J Steroid Biochem Mol Biol
, vol.109
, pp. 247-253
-
-
Chouinard, S.1
Yueh, M.F.2
Tukey, R.H.3
Giton, F.4
Fiet, J.5
Pelletier, G.6
Barbier, O.7
Bélanger, A.8
-
4
-
-
22244433169
-
Meditation reduces sympathetic activation and improves the quality of life in elderly patients with optimally treated heart failure: A prospective randomized study
-
Curiati JA, Bocchi E, Freire JO, Arantes AC, Braga M, Garcia Y, Guimarães G, and Fo WJ (2005) Meditation reduces sympathetic activation and improves the quality of life in elderly patients with optimally treated heart failure: a prospective randomized study. J Altern Complement Med 11:465-472.
-
(2005)
J Altern Complement Med
, vol.11
, pp. 465-472
-
-
Curiati, J.A.1
Bocchi, E.2
Freire, J.O.3
Arantes, A.C.4
Braga, M.5
Garcia, Y.6
Guimarães, G.7
Fo, W.J.8
-
5
-
-
36749085081
-
Determination of deoxyschizandrin in rat plasma by LC-MS
-
Deng X, Chen X, Yin R, Shen Z, Qiao L, and Bi K (2008) Determination of deoxyschizandrin in rat plasma by LC-MS. J Pharm Biomed Anal 46:121-126.
-
(2008)
J Pharm Biomed Anal
, vol.46
, pp. 121-126
-
-
Deng, X.1
Chen, X.2
Yin, R.3
Shen, Z.4
Qiao, L.5
Bi, K.6
-
6
-
-
0036491604
-
Development of therapeutics: Opportunities within complementary and alternative medicine
-
Engel LW and Straus SE (2002) Development of therapeutics: opportunities within complementary and alternative medicine. Nat Rev Drug Discov 1:229-237.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 229-237
-
-
Engel, L.W.1
Straus, S.E.2
-
7
-
-
0028596404
-
Gender differences in human pharmacokinetics and pharmacodynamics
-
Fletcher CV, Acosta EP, and Strykowski JM (1994) Gender differences in human pharmacokinetics and pharmacodynamics. J Adolesc Health 15:619-629.
-
(1994)
J Adolesc Health
, vol.15
, pp. 619-629
-
-
Fletcher, C.V.1
Acosta, E.P.2
Strykowski, J.M.3
-
9
-
-
8544273223
-
Complementary and alternative medicine: Assessing the evidence for immunological benefits
-
DOI 10.1038/nri1486
-
Goldrosen MH and Straus SE (2004) Complementary and alternative medicine: assessing the evidence for immunological benefits. Nat Rev Immunol 4:912-921. (Pubitemid 39490766)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.11
, pp. 912-921
-
-
Goldrosen, M.H.1
Straus, S.E.2
-
10
-
-
55549122656
-
Global detection and identification of nontarget components from herbal preparations by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a strategy
-
Hao H, Cui N, Wang G, Xiang B, Liang Y, Xu X, Zhang H, Yang J, Zheng C, Wu L, et al. (2008) Global detection and identification of nontarget components from herbal preparations by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a strategy. Anal Chem 80:8187-8194.
-
(2008)
Anal Chem
, vol.80
, pp. 8187-8194
-
-
Hao, H.1
Cui, N.2
Wang, G.3
Xiang, B.4
Liang, Y.5
Xu, X.6
Zhang, H.7
Yang, J.8
Zheng, C.9
Wu, L.10
-
11
-
-
42649097230
-
Structural characterization and identification of dibenzocyclooctadiene lignans in Fructus Schisandrae using electrospray ionization ion trap multiple-stage tandem mass spectrometry and electrospray ionization Fourier transform ion cyclotron resonance multiple-stage tandem mass spectrometry
-
Huang X, Song F, Liu Z, and Liu S (2008) Structural characterization and identification of dibenzocyclooctadiene lignans in Fructus Schisandrae using electrospray ionization ion trap multiple-stage tandem mass spectrometry and electrospray ionization Fourier transform ion cyclotron resonance multiple-stage tandem mass spectrometry. Analytica chimica acta 615:124-135.
-
(2008)
Analytica Chimica Acta
, vol.615
, pp. 124-135
-
-
Huang, X.1
Song, F.2
Liu, Z.3
Liu, S.4
-
12
-
-
8844227477
-
Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines
-
DOI 10.1016/j.jchromb.2004.06.046, PII S157002320400546X
-
Huang XD, Kong L, Li X, Chen XG, Guo M, and Zou HF (2004) Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines. J Chromatogr B Analyt Technol Biomed Life Sci 812:71-84. (Pubitemid 39535402)
-
(2004)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.812
, Issue.1-2 SPEC. ISS
, pp. 71-84
-
-
Huang, X.1
Kong, L.2
Li, X.3
Chen, X.4
Guo, M.5
Zou, H.6
-
13
-
-
0003633755
-
-
Institute of Laboratory Animal Resources 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC
-
Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
14
-
-
9444257635
-
Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract
-
DOI 10.1124/dmd.104.000646
-
Iwata H, Tezuka Y, Kadota S, Hiratsuka A, and Watabe T (2004) Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract. Drug Metab Dispos 32:1351-1358. (Pubitemid 39564554)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.12
, pp. 1351-1358
-
-
Iwata, H.1
Tezuka, Y.2
Kadota, S.3
Hiratsuka, A.4
Watabe, T.5
-
15
-
-
70549090936
-
Recent analytical approaches in quality control of traditional Chinese medicines - A review
-
Jiang Y, David B, Tu P, and Barbin Y (2010) Recent analytical approaches in quality control of traditional Chinese medicines-a review. Anal Chim Acta 657:9-18.
-
(2010)
Anal Chim Acta
, vol.657
, pp. 9-18
-
-
Jiang, Y.1
David, B.2
Tu, P.3
Barbin, Y.4
-
16
-
-
47649092211
-
How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs
-
Kong DX, Li XJ, Tang GY, and Zhang HY (2008) How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs. Chem Med Chem 3:233-236.
-
(2008)
Chem Med Chem
, vol.3
, pp. 233-236
-
-
Kong, D.X.1
Li, X.J.2
Tang, G.Y.3
Zhang, H.Y.4
-
17
-
-
71049138996
-
Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats
-
Lai L, Hao HP, Wang Q, Zheng CN, Zhou F, Liu YT, Wang YX, Yu G, Kang A, Peng Y, et al. (2009) Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats. Drug Metab Dispos 37:2399-2407.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2399-2407
-
-
Lai, L.1
Hao, H.P.2
Wang, Q.3
Zheng, C.N.4
Zhou, F.5
Liu, Y.T.6
Wang, Y.X.7
Yu, G.8
Kang, A.9
Peng, Y.10
-
18
-
-
45849091861
-
Synergy in natural medicines: Implications for drug discovery
-
Li XJ and Zhang HY (2008) Synergy in natural medicines: implications for drug discovery. Trends Pharmacol Sci 29:331-332.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 331-332
-
-
Li, X.J.1
Zhang, H.Y.2
-
19
-
-
60349120689
-
Analysis of Schisandra chinensis and Schisandra sphenanthera
-
Lu Y and Chen DF (2009) Analysis of Schisandra chinensis and Schisandra sphenanthera. J Chromatogr A 1216:1980-1990.
-
(2009)
J Chromatogr A
, vol.1216
, pp. 1980-1990
-
-
Lu, Y.1
Chen, D.F.2
-
20
-
-
34250705787
-
Intestinal first-pass metabolism via carboxylesterase in rat jejunum and ileum
-
Masaki K, Hashimoto M, and Imai T (2007) Intestinal first-pass metabolism via carboxylesterase in rat jejunum and ileum. Drug Metab Dispos 35:1089-1095.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1089-1095
-
-
Masaki, K.1
Hashimoto, M.2
Imai, T.3
-
21
-
-
0022357580
-
Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16α-hydroxylase cytochrome P-450 apoprotein in the rat
-
Morgan ET, MacGeoch C, and Gustafsson JA (1985) Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16α-hydroxylase cytochrome P-450 apoprotein in the rat. J Biol Chem 260:11895-11898.
-
(1985)
J Biol Chem
, vol.260
, pp. 11895-11898
-
-
Morgan, E.T.1
MacGeoch, C.2
Gustafsson, J.A.3
-
22
-
-
0022965367
-
Mutagenic activation of carcinogenic N-nitrosopropylamines by liver S9 fractions from mice, rats and hamsters: Evidence for a cytochrome P-450-dependent reaction
-
Mori Y, Yamazaki H, Toyoshi K, Denda A, and Konishi Y (1986) Mutagenic activation of carcinogenic N-nitrosopropylamines by liver S9 factions from mice, rats and hamsters: evidence for a cytochrome P450-dependent reaction. Carcinogenesis 7:375-379. (Pubitemid 17130545)
-
(1986)
Carcinogenesis
, vol.7
, Issue.3
, pp. 375-379
-
-
Mori, Y.1
Yamazaki, H.2
Toyoshi, K.3
-
23
-
-
68349137944
-
Sex differences in the subcellular distribution of angiotensin type 1 receptors and NADPH oxidase subunits in the dendrites of C1 neurons in the rat rostral ventrolateral medulla
-
Pierce JP, Kievits J, Graustein B, Speth RC, Iadecola C, and Milner TA (2009) Sex differences in the subcellular distribution of angiotensin type 1 receptors and NADPH oxidase subunits in the dendrites of C1 neurons in the rat rostral ventrolateral medulla. Neuroscience 163:329-338.
-
(2009)
Neuroscience
, vol.163
, pp. 329-338
-
-
Pierce, J.P.1
Kievits, J.2
Graustein, B.3
Speth, R.C.4
Iadecola, C.5
Milner, T.A.6
-
24
-
-
0023912356
-
Electroacupuncture suppression of a nociceptive reflex is potentiated by two repeated electroacupuncture treatments: The first opioid effect potentiates a second non-opioid effect
-
Pomeranz B and Warma N (1988) Electroacupuncture suppression of a nociceptive reflex is potentiated by two repeated electroacupuncture treatments: the first opioid effect potentiates a second non-opioid effect. Brain Res 452:232-236.
-
(1988)
Brain Res
, vol.452
, pp. 232-236
-
-
Pomeranz, B.1
Warma, N.2
-
25
-
-
33646036730
-
Complementary and alternative medicine for advanced prostate cancer
-
viii
-
Rackley JD, Clark PE, and Hall MC (2006) Complementary and alternative medicine for advanced prostate cancer. Urol Clin North Am 33:237-246, viii.
-
(2006)
Urol Clin North Am
, vol.33
, pp. 237-246
-
-
Rackley, J.D.1
Clark, P.E.2
Hall, M.C.3
-
26
-
-
0000391723
-
Effect of starvation on NADPH-dependent enzymes in liver microsomes of male and female rats
-
Ryuichi K and James RG (1965) Effect of starvation on NADPH-dependent enzymes in liver microsomes of male and female rats. J Pharmacol Exp Ther 2:279-284.
-
(1965)
J Pharmacol Exp Ther
, vol.2
, pp. 279-284
-
-
Ryuichi, K.1
James, R.G.2
-
27
-
-
33644557409
-
Inducibility of male-specific isoforms of cytochrome P450 by sex-dependent growth hormone profiles in hepatocyte cultures from male but not female rats
-
DOI 10.1124/dmd.105.007716
-
Thangavel C, Dworakowski W, and Shapiro BH (2006) Inducibility of male-specific isoforms of cytochrome P450 by sex-dependent growth hormone profiles in hepatocyte cultures from male but not female rats. Drug Metab Dispos 34:410-419. (Pubitemid 43292550)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.3
, pp. 410-419
-
-
Thangavel, C.1
Dworakowski, W.2
Shapiro, B.H.3
-
28
-
-
0014867701
-
The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats
-
Theodore EG, Anthony MG, David HS, Donald CD, Reginald LR, and James RG (1970) The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats. J Pharmacol Exp Ther 1:12-21.
-
(1970)
J Pharmacol Exp Ther
, vol.1
, pp. 12-21
-
-
Theodore, E.G.1
Anthony, M.G.2
David, H.S.3
Donald, C.D.4
Reginald, L.R.5
James, R.G.6
-
29
-
-
0031739467
-
Alterations in the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices
-
VandenBranden M, Wrighton SA, Ekins S, Gillespie JS, Binkley SN, Ring BJ, Gadberry MG, Mullins DC, Strom SC, and Jensen CB (1998) Alterations in the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices. Drug Metab Dispos 26:1063-1068.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 1063-1068
-
-
VandenBranden, M.1
Wrighton, S.A.2
Ekins, S.3
Gillespie, J.S.4
Binkley, S.N.5
Ring, B.J.6
Gadberry, M.G.7
Mullins, D.C.8
Strom, S.C.9
Jensen, C.B.10
-
30
-
-
0027168407
-
The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance
-
Vickers AE, Connors S, Zollinger M, Biggi WA, Larrauri A, Vogelaar JP, and Brendel K (1993) The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance. Drug Metab Dispos 21:454-459.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 454-459
-
-
Vickers, A.E.1
Connors, S.2
Zollinger, M.3
Biggi, W.A.4
Larrauri, A.5
Vogelaar, J.P.6
Brendel, K.7
-
31
-
-
70349986461
-
An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis
-
Wang Y, Hao H, Wang G, Tu P, Jiang Y, Liang Y, Dai L, Yang H, Lai L, Zheng C, et al. (2009) An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis. Talanta 80:572-580.
-
(2009)
Talanta
, vol.80
, pp. 572-580
-
-
Wang, Y.1
Hao, H.2
Wang, G.3
Tu, P.4
Jiang, Y.5
Liang, Y.6
Dai, L.7
Yang, H.8
Lai, L.9
Zheng, C.10
-
32
-
-
48249150036
-
Sex-specific early growth hormone response genes in rat liver
-
Wauthier V and Waxman DJ (2008) Sex-specific early growth hormone response genes in rat liver. Mol Endocrinol 22:1962-1974.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1962-1974
-
-
Wauthier, V.1
Waxman, D.J.2
-
33
-
-
67650841094
-
Sex differences in the expression of hepatic drug metabolizing enzymes
-
Waxman DJ and Holloway MG (2009) Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol 76:215-228.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 215-228
-
-
Waxman, D.J.1
Holloway, M.G.2
-
34
-
-
37349022457
-
Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, Fructus Schisandrae aqueous extract and Sheng-Mai-San to rats
-
DOI 10.1016/j.jep.2007.10.016, PII S037887410700548X
-
Xu MJ, Wang GJ, Xie HT, Huang Q, Wang W, and Jia YW (2008) Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, Fructus Schisandrae aqueous extract and Sheng-Mai-San to rats. J Ethnopharmacol 115:483-488. (Pubitemid 350299087)
-
(2007)
Journal of Ethnopharmacology
, vol.115
, Issue.3
, pp. 483-488
-
-
Xu, M.1
Wang, G.2
Xie, H.3
Huang, Q.4
Wang, W.5
Jia, Y.6
-
35
-
-
60349129230
-
Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry
-
Yang M, Sun J, Lu Z, Chen G, Guan S, Liu X, Jiang B, Ye M, and Guo DA (2009) Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J Chromatogr A 1216:2045-2062.
-
(2009)
J Chromatogr A
, vol.1216
, pp. 2045-2062
-
-
Yang, M.1
Sun, J.2
Lu, Z.3
Chen, G.4
Guan, S.5
Liu, X.6
Jiang, B.7
Ye, M.8
Guo, D.A.9
-
36
-
-
33746681910
-
Tissue-specific expression and regulation of sexually dimorphic genes in mice
-
DOI 10.1101/gr.5217506
-
Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, Drake TA, and Lusis AJ (2006) Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res 16:995-1004. (Pubitemid 44162259)
-
(2006)
Genome Research
, vol.16
, Issue.8
, pp. 995-1004
-
-
Yang, X.1
Schadt, E.E.2
Wang, S.3
Wang, H.4
Arnold, A.P.5
Ingram-Drake, L.6
Drake, T.A.7
Lusis, A.J.8
-
37
-
-
0033625056
-
Traditional Chinese medicinean approach to scientific proof and clinical validation
-
DOI 10.1016/S0163-7258(00)00039-5, PII S0163725800000395
-
Yuan R and Lin Y (2000) Traditional Chinese medicine: an approach to scientific proof and clinical validation. Pharmacol Ther 86:191-198. (Pubitemid 30229901)
-
(2000)
Pharmacology and Therapeutics
, vol.86
, Issue.2
, pp. 191-198
-
-
Yuan, R.1
Lin, Y.2
-
38
-
-
59949083512
-
Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI-IT-TOF/MS: Shengmai injection as an example
-
Zheng C, Hao H, Wang X, Wu X, Wang G, Sang G, Liang Y, Xie L, Xia C, and Yao X (2009) Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI-IT-TOF/MS: Shengmai injection as an example. J Mass Spectrom 44:230-244.
-
(2009)
J Mass Spectrom
, vol.44
, pp. 230-244
-
-
Zheng, C.1
Hao, H.2
Wang, X.3
Wu, X.4
Wang, G.5
Sang, G.6
Liang, Y.7
Xie, L.8
Xia, C.9
Yao, X.10
|