-
1
-
-
77954243018
-
Formation of plexiform lesions in experimental severe pulmonary arterial hypertension
-
Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, Voelkel NF, Mc Murtry IF, Oka M. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation 121: 2747-2754, 2010.
-
(2010)
Circulation
, vol.121
, pp. 2747-2754
-
-
Abe, K.1
Toba, M.2
Alzoubi, A.3
Ito, M.4
Fagan, K.A.5
Cool, C.D.6
Voelkel, N.F.7
Mc Murtry, I.F.8
Oka, M.9
-
2
-
-
34548049239
-
The Decapentaplegic morphogen gradient: From pattern formation to growth regulation
-
Affolter M, Basler K. The Decapentaplegic morphogen gradient: From pattern formation to growth regulation. Nat Rev Genet 8: 663-674, 2007.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 663-674
-
-
Affolter, M.1
Basler, K.2
-
3
-
-
0345276632
-
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
-
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, Dimmeler S. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9: 1370-1376, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 1370-1376
-
-
Aicher, A.1
Heeschen, C.2
Mildner-Rihm, C.3
Urbich, C.4
Ihling, C.5
Technau-Ihling, K.6
Zeiher, A.M.7
Dimmeler, S.8
-
4
-
-
32544438253
-
BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension
-
Aldred MA, Vijayakrishnan J, James V, Soubrier F, Gomez-Sanchez MA, Martensson G, Galie N, Manes A, Corris P, Simonneau G, Humbert M, Morrell NW, Trembath RC. BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. HumMutat 27: 212-213, 2006.
-
(2006)
HumMutat
, vol.27
, pp. 212-213
-
-
Aldred, M.A.1
Vijayakrishnan, J.2
James, V.3
Soubrier, F.4
Gomez-Sanchez, M.A.5
Martensson, G.6
Galie, N.7
Manes, A.8
Corris, P.9
Simonneau, G.10
Humbert, M.11
Morrell, N.W.12
Trembath, R.C.13
-
5
-
-
0000094743
-
Pulmonary hypertention and right ventricular hypertrophy in cattle at high altitude
-
Alexander AF, Will DH, Grover RF, Reeves JT. Pulmonary hypertention and right ventricular hypertrophy in cattle at high altitude. Am J Vet Res 21: 199-204, 1960.
-
(1960)
Am J Vet Res
, vol.21
, pp. 199-204
-
-
Alexander, A.F.1
Will, D.H.2
Grover, R.F.3
Reeves, J.T.4
-
6
-
-
17944368283
-
The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor
-
Ambartsumian N, Klingelhofer J, Grigorian M, Christensen C, Kriajevska M, Tulchinsky E, Georgiev G, Berezin V, Bock E, Rygaard J, Cao R, Cao Y, Lukanidin E. The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor. Oncogene 20: 4685-4695, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 4685-4695
-
-
Ambartsumian, N.1
Klingelhofer, J.2
Grigorian, M.3
Christensen, C.4
Kriajevska, M.5
Tulchinsky, E.6
Georgiev, G.7
Berezin, V.8
Bock, E.9
Rygaard, J.10
Cao, R.11
Cao, Y.12
Lukanidin, E.13
-
7
-
-
5644247979
-
Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction
-
Amiri F, Virdis A, Neves MF, Iglarz M, Seidah NG, Touyz RM, Reudelhuber TL, Schiffrin EL. Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction. Circulation 110: 2233-2240, 2004.
-
(2004)
Circulation
, vol.110
, pp. 2233-2240
-
-
Amiri, F.1
Virdis, A.2
Neves, M.F.3
Iglarz, M.4
Seidah, N.G.5
Touyz, R.M.6
Reudelhuber, T.L.7
Schiffrin, E.L.8
-
8
-
-
77749328893
-
Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension
-
Anderson L, Lowery JW, Frank DB, Novitskaya T, Jones M, Mortlock DP, Chandler RL, de Caestecker MP. Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol 298(3): R833-842, 2010.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
, Issue.3
-
-
Anderson, L.1
Lowery, J.W.2
Frank, D.B.3
Novitskaya, T.4
Jones, M.5
Mortlock, D.P.6
Chandler, R.L.7
de Caestecker, M.P.8
-
9
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
Kuriyama, H.11
Nishida, M.12
Yamashita, S.13
Okubo, K.14
Matsubara, K.15
Muraguchi, M.16
Ohmoto, Y.17
Funahashi, T.18
Matsuzawa, Y.19
-
10
-
-
48349087208
-
Vasoactive intestinal peptide as a healing mediator in Crohn's disease
-
Arranz A, Abad C, Juarranz Y, Leceta J, Martinez C, Gomariz RP. Vasoactive intestinal peptide as a healing mediator in Crohn's disease. Neuroimmunomodulation 15: 46-53, 2008.
-
(2008)
Neuroimmunomodulation
, vol.15
, pp. 46-53
-
-
Arranz, A.1
Abad, C.2
Juarranz, Y.3
Leceta, J.4
Martinez, C.5
Gomariz, R.P.6
-
11
-
-
70349678823
-
Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis
-
Asano T, Watanabe K, Kubota N, Gunji T, Omata M, Kadowaki T, Ohnishi S. Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis. J Gastroenterol Hepatol 24: 1669-1676, 2009.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 1669-1676
-
-
Asano, T.1
Watanabe, K.2
Kubota, N.3
Gunji, T.4
Omata, M.5
Kadowaki, T.6
Ohnishi, S.7
-
12
-
-
20044362444
-
Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons
-
Aton SJ, Colwell CS, Harmar AJ, Waschek J, Herzog ED. Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat Neurosci 8: 476-483, 2005.
-
(2005)
Nat Neurosci
, vol.8
, pp. 476-483
-
-
Aton, S.J.1
Colwell, C.S.2
Harmar, A.J.3
Waschek, J.4
Herzog, E.D.5
-
14
-
-
0037092565
-
CX(3)C chemokine fractalkine in pulmonary arterial hypertension
-
Balabanian K, Foussat A, Dorfmuller P, Durand-Gasselin I, Capel F, Bouchet-Delbos L, Portier A, Marfaing-Koka A, Krzysiek R, Rimaniol AC, Simonneau G, Emilie D, Humbert M. CX(3)C chemokine fractalkine in pulmonary arterial hypertension. Am J Respir Crit Care Med 165: 1419-1425, 2002.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1419-1425
-
-
Balabanian, K.1
Foussat, A.2
Dorfmuller, P.3
Durand-Gasselin, I.4
Capel, F.5
Bouchet-Delbos, L.6
Portier, A.7
Marfaing-Koka, A.8
Krzysiek, R.9
Rimaniol, A.C.10
Simonneau, G.11
Emilie, D.12
Humbert, M.13
-
15
-
-
0030452395
-
Pulmonary hypertension in schistosomiasis mansoni
-
Barbosa MM, Lamounier JA, Oliveira EC, Souza MV, Marques DS, Silva AA, Lambertucci Jr. Pulmonary hypertension in schistosomiasis mansoni. Trans R Soc Trop Med Hyg 90: 663-665, 1996.
-
(1996)
Trans R Soc Trop Med Hyg
, vol.90
, pp. 663-665
-
-
Barbosa, M.M.1
Lamounier, J.A.2
Oliveira, E.C.3
Souza, M.V.4
Marques, D.S.5
Silva, A.A.6
Lambertucci, Jr.7
-
16
-
-
8644256840
-
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
-
Beppu H, Ichinose F, Kawai N, Jones RC, Yu PB, Zapol WM, Miyazono K, Li E, Bloch KD. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol 287: L1241-1247, 2004.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Beppu, H.1
Ichinose, F.2
Kawai, N.3
Jones, R.C.4
Yu, P.B.5
Zapol, W.M.6
Miyazono, K.7
Li, E.8
Bloch, K.D.9
-
17
-
-
0034193390
-
BMP type II receptor is required for gastrulation and early development of mouse embryos
-
Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K. BMP type II receptor is required for gastrulation and early development of mouse embryos. Dev Biol 221: 249-258, 2000.
-
(2000)
Dev Biol
, vol.221
, pp. 249-258
-
-
Beppu, H.1
Kawabata, M.2
Hamamoto, T.3
Chytil, A.4
Minowa, O.5
Noda, T.6
Miyazono, K.7
-
18
-
-
0031724886
-
Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary hypertension
-
Black SM, Fineman JR, Steinhorn RH, Bristow J, Soifer SJ. Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol 275: H1643-H1651, 1998.
-
(1998)
Am J Physiol
, vol.275
-
-
Black, S.M.1
Fineman, J.R.2
Steinhorn, R.H.3
Bristow, J.4
Soifer, S.J.5
-
19
-
-
54049115421
-
The heterozygous Sod2(+/-) mouse: Modeling the mitochondrial role in drug toxicity
-
Boelsterli UA, Hsiao CJ. The heterozygous Sod2(+/-) mouse: Modeling the mitochondrial role in drug toxicity. Drug Discov Today 13: 982-988, 2008.
-
(2008)
Drug Discov Today
, vol.13
, pp. 982-988
-
-
Boelsterli, U.A.1
Hsiao, C.J.2
-
20
-
-
0034234368
-
Systemic lobar shunting induces advanced pulmonary vasculopathy
-
Bousamra M II, Rossi R, Jacobs E, Parviz M, Busch C, Nelin LD, Haworth S, Dawson CA. Systemic lobar shunting induces advanced pulmonary vasculopathy. J Thorac Cardiovasc Surg 120: 88-98, 2000.
-
(2000)
J Thorac Cardiovasc Surg
, vol.120
, pp. 88-98
-
-
Bousamra II, M.1
Rossi, R.2
Jacobs, E.3
Parviz, M.4
Busch, C.5
Nelin, L.D..6
Haworth, S.7
Dawson, C.A.8
-
21
-
-
76149146685
-
S100A4 and metastasis: A small actor playing many roles
-
Boye K, Maelandsmo GM. S100A4 and metastasis: A small actor playing many roles. Am J Pathol 176(2): 528-35, 2010.
-
(2010)
Am J Pathol
, vol.176
, Issue.2
, pp. 528-535
-
-
Boye, K.1
Maelandsmo, G.M.2
-
22
-
-
62549162561
-
Longterm exposure to hypobaric hypoxia in rat affects femur cross-sectional geometry and bone tissue material properties
-
Bozzini C, Olivera MI, Huygens P, Alippi RM, Bozzini CE. Longterm exposure to hypobaric hypoxia in rat affects femur cross-sectional geometry and bone tissue material properties. Ann Anat 191: 212-217, 2009.
-
(2009)
Ann Anat
, vol.191
, pp. 212-217
-
-
Bozzini, C.1
Olivera, M.I.2
Huygens, P.3
Alippi, R.M.4
Bozzini, C.E.5
-
23
-
-
67651238345
-
Sustained hypoxia promotes the development of a pulmonary artery specific chronic inflammatory microenvironment
-
Burke DL, Frid MG, Kunrath CL, Karoor V, Anwar A, Wagner BD, Strassheim D, Stenmark KR. Sustained hypoxia promotes the development of a pulmonary artery specific chronic inflammatory microenvironment. Am J Physiol Lung Cell Mol Physiol 297(2): L238-250, 2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, Issue.2
-
-
Burke, D.L.1
Frid, M.G.2
Kunrath, C.L.3
Karoor, V.4
Anwar, A.5
Wagner, B.D.6
Strassheim, D.7
Stenmark, K.R.8
-
24
-
-
77953786515
-
Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat
-
Casey DB, Badejo AM, Dhaliwal JS, Sikora JL, Fokin A, Golwala NH, Greco AJ, Murthy SN, Nossaman BD, Hyman AL, Kadowitz PJ. Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat. Am J Physiol Heart Circ Physiol 299: H184-H192, 2010.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
-
-
Casey, D.B.1
Badejo, A.M.2
Dhaliwal, J.S.3
Sikora, J.L.4
Fokin, A.5
Golwala, N.H.6
Greco, A.J.7
Murthy, S.N.8
Nossaman, B.D.9
Hyman, A.L.10
Kadowitz, P.J.11
-
25
-
-
23144451546
-
Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity
-
Chaiswing L, Cole MP, Ittarat W, Szweda LI, St Clair DK, Oberley TD. Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity. Mol Cancer Ther 4: 1056-1064, 2005.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1056-1064
-
-
Chaiswing, L.1
Cole, M.P.2
Ittarat, W.3
Szweda, L.I.4
St Clair, D.K.5
Oberley, T.D.6
-
26
-
-
70049098149
-
Role for interleukin-6 in COPD-related pulmonary hypertension
-
Chaouat A, Savale L, Chouaid C, Tu L, Sztrymf B, Canuet M, Maitre B, Housset B, Brandt C, Le Corvoisier P, Weitzenblum E, Eddahibi S, Adnot S. Role for interleukin-6 in COPD-related pulmonary hypertension. Chest 136: 678-687, 2009.
-
(2009)
Chest
, vol.136
, pp. 678-687
-
-
Chaouat, A.1
Savale, L.2
Chouaid, C.3
Tu, L.4
Sztrymf, B.5
Canuet, M.6
Maitre, B.7
Housset, B.8
Brandt, C.9
Le Corvoisier, P.10
Weitzenblum, E.11
Eddahibi, S.12
Adnot, S.13
-
27
-
-
0031916129
-
Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice
-
Clouthier DE, Hosoda K, Richardson JA, Williams SC, Yanagisawa H, Kuwaki T, Kumada M, Hammer RE, Yanagisawa M. Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development 125: 813-824, 1998.
-
(1998)
Development
, vol.125
, pp. 813-824
-
-
Clouthier, D.E.1
Hosoda, K.2
Richardson, J.A.3
Williams, S.C.4
Yanagisawa, H.5
Kuwaki, T.6
Kumada, M.7
Hammer, R.E.8
Yanagisawa, M.9
-
28
-
-
0042634149
-
Liver inflammation during monocrotaline hepatotoxicity
-
Copple BL, Ganey PE, Roth RA. Liver inflammation during monocrotaline hepatotoxicity. Toxicology 190: 155-169, 2003.
-
(2003)
Toxicology
, vol.190
, pp. 155-169
-
-
Copple, B.L.1
Ganey, P.E.2
Roth, R.A.3
-
29
-
-
66749129603
-
Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene
-
Crona D, Harral J, Adnot S, Eddahibi S, West J. Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene. BMC Pulm Med 9: 19, 2009.
-
(2009)
BMC Pulm Med
, vol.9
, pp. 19
-
-
Crona, D.1
Harral, J.2
Adnot, S.3
Eddahibi, S.4
West, J.5
-
30
-
-
76749098219
-
Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis
-
Crosby A, Jones FM, Southwood M, Stewart S, Schermuly R, Butrous G, Dunne DW, Morrell NW. Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis. Am J Respir Crit Care Med 181(3): 279-288, 2010.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.3
, pp. 279-288
-
-
Crosby, A.1
Jones, F.M.2
Southwood, M.3
Stewart, S.4
Schermuly, R.5
Butrous, G.6
Dunne, D.W.7
Morrell, N.W.8
-
31
-
-
42649085057
-
Changes and distributions of peptides derived from proadrenomedullin in left-toright shunt pulmonary hypertension of rats
-
Cuifen Z, Lijuan W, Li G, Wei X, Zhiyu W, Fuhai L. Changes and distributions of peptides derived from proadrenomedullin in left-toright shunt pulmonary hypertension of rats. Circ J 72: 476-481, 2008.
-
(2008)
Circ J
, vol.72
, pp. 476-481
-
-
Cuifen, Z.1
Lijuan, W.2
Li, G.3
Wei, X.4
Zhiyu, W.5
Fuhai, L.6
-
32
-
-
39549087002
-
Pulmonary arterial remodeling induced by a Th2 immune response
-
Daley E, Emson C, Guignabert C, deWaal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G. Pulmonary arterial remodeling induced by a Th2 immune response. J ExpMed 205: 361-372, 2008.
-
(2008)
J ExpMed
, vol.205
, pp. 361-372
-
-
Daley, E.1
Emson, C.2
Guignabert, C.3
deWaal Malefyt, R.4
Louten, J.5
Kurup, V.P.6
Hogaboam, C.7
Taraseviciene-Stewart, L.8
Voelkel, N.F.9
Rabinovitch, M.10
Grunig, E.11
Grunig, G.12
-
33
-
-
0014831437
-
Fasting glucose homeostasis in rats after chronic exposure to hypoxia
-
Davidson MB, Aoki VS. Fasting glucose homeostasis in rats after chronic exposure to hypoxia. Am J Physiol 219: 378-383, 1970.
-
(1970)
Am J Physiol
, vol.219
, pp. 378-383
-
-
Davidson, M.B.1
Aoki, V.S.2
-
34
-
-
0029860590
-
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours
-
Davies MP, Rudland PS, Robertson L, Parry EW, Jolicoeur P, Barraclough R. Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. Oncogene 13: 1631-1637, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 1631-1637
-
-
Davies, M.P.1
Rudland, P.S.2
Robertson, L.3
Parry, E.W.4
Jolicoeur, P.5
Barraclough, R.6
-
35
-
-
0028131895
-
Effects of a chronic aortopulmonary shunt on pulmonary hemodynamics in piglets
-
De Canniere D, Stefanidis C, Brimioulle S, Naeije R. Effects of a chronic aortopulmonary shunt on pulmonary hemodynamics in piglets. J Appl Physiol 77: 1591-1596, 1994.
-
(1994)
J Appl Physiol
, vol.77
, pp. 1591-1596
-
-
De Canniere, D.1
Stefanidis, C.2
Brimioulle, S.3
Naeije, R.4
-
36
-
-
77950191501
-
Hypoxia and dehydroepiandrosterone in old age: A mouse survival study
-
Debonneuil EH, Quillard J, Baulieu EE. Hypoxia and dehydroepiandrosterone in old age: A mouse survival study. Respir Res 7: 144, 2006.
-
(2006)
Respir Res
, vol.7
, pp. 144
-
-
Debonneuil, E.H.1
Quillard, J.2
Baulieu, E.E.3
-
37
-
-
73649092112
-
-
Degano B, Guillaume M, Savale L, Montani D, Jais X, Yaici A, Le Pavec J, Humbert M, Simonneau G, Sitbon O. HIV-associated pulmonary arterial hypertension: Survival and prognostic factors in the modern therapeutic era. AIDS 24: 67-75.
-
-
-
-
38
-
-
52949150059
-
Anti-inflammatory neuropeptides:Anewclass of endogenous immunoregulatory agents
-
Delgado M, Ganea D. Anti-inflammatory neuropeptides:Anewclass of endogenous immunoregulatory agents. Brain Behav Immun 22: 1146-1151, 2008.
-
(2008)
Brain Behav Immun
, vol.22
, pp. 1146-1151
-
-
Delgado, M.1
Ganea, D.2
-
39
-
-
0037235556
-
BMP signaling is required for septation of the outflow tract of the mammalian heart
-
Delot EC, Bahamonde ME, Zhao M, Lyons KM. BMP signaling is required for septation of the outflow tract of the mammalian heart. Development 130: 209-220, 2003.
-
(2003)
Development
, vol.130
, pp. 209-220
-
-
Delot, E.C.1
Bahamonde, M.E.2
Zhao, M.3
Lyons, K.M.4
-
40
-
-
44649106435
-
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice
-
Dempsie Y, Morecroft I, Welsh DJ, Mac Ritchie NA, Herold N, Loughlin L, Nilsen M, Peacock AJ, Harmar A, Bader M, Mac Lean MR. Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation 117: 2928-2937, 2008.
-
(2008)
Circulation
, vol.117
, pp. 2928-2937
-
-
Dempsie, Y.1
Morecroft, I.2
Welsh, D.J.3
Mac Ritchie, N.A.4
Herold, N.5
Loughlin, L.6
Nilsen, M.7
Peacock, A.J.8
Harmar, A.9
Bader, M.10
Mac Lean, M.R.11
-
41
-
-
44649134618
-
Pulmonary hypertension caused by sarcoidosis
-
Diaz-Guzman E, Farver C, Parambil J, Culver DA. Pulmonary hypertension caused by sarcoidosis. Clin Chest Med 29: 549-563, 2008.
-
(2008)
Clin Chest Med
, vol.29
, pp. 549-563
-
-
Diaz-Guzman, E.1
Farver, C.2
Parambil, J.3
Culver, D.A.4
-
42
-
-
33846837071
-
Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene. BMPRII
-
Donn R, Berry A, Stevens A, Farrow S, Betts J, Stevens R, Clayton C, Wang J, Warnock L, Worthington J, Scott L, Graham S, Ray D. Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII. FASEB J 21: 402-414, 2007.
-
(2007)
FASEB J
, vol.21
, pp. 402-414
-
-
Donn, R.1
Berry, A.2
Stevens, A.3
Farrow, S.4
Betts, J.5
Stevens, R.6
Clayton, C.7
Wang, J.8
Warnock, L.9
Worthington, J.10
Scott, L.11
Graham, S.12
Ray, D.13
-
43
-
-
0035964954
-
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
-
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293: 2449-2452, 2001.
-
(2001)
Science
, vol.293
, pp. 2449-2452
-
-
Drab, M.1
Verkade, P.2
Elger, M.3
Kasper, M.4
Lohn, M.5
Lauterbach, B.6
Menne, J.7
Lindschau, C.8
Mende, F.9
Luft, F.C.10
Schedl, A.11
Haller, H.12
Kurzchalia, T.V.13
-
44
-
-
63349108329
-
Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury
-
Dumitrascu R, Koebrich S, Dony E, Weissmann N, Savai R, Pullamsetti SS, Ghofrani HA, Samidurai A, Traupe H, Seeger W, Grimminger F, Schermuly RT. Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury. BMC Pulm Med 8: 25, 2008.
-
(2008)
BMC Pulm Med
, vol.8
, pp. 25
-
-
Dumitrascu, R.1
Koebrich, S.2
Dony, E.3
Weissmann, N.4
Savai, R.5
Pullamsetti, S.S.6
Ghofrani, H.A.7
Samidurai, A.8
Traupe, H.9
Seeger, W.10
Grimminger, F.11
Schermuly, R.T.12
-
45
-
-
0031571651
-
Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4
-
Dunn NR, Winnier GE, Hargett LK, Schrick JJ, Fogo AB, Hogan BL. Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. Dev Biol 188: 235-247, 1997.
-
(1997)
Dev Biol
, vol.188
, pp. 235-247
-
-
Dunn, N.R.1
Winnier, G.E.2
Hargett, L.K.3
Schrick, J.J.4
Fogo, A.B.5
Hogan, B.L.6
-
46
-
-
67651216391
-
Adipokines as regulators of muscle metabolism and insulin sensitivity
-
Dyck DJ. Adipokines as regulators of muscle metabolism and insulin sensitivity. Appl Physiol Nutr Metab 34: 396-402, 2009.
-
(2009)
Appl Physiol Nutr Metab
, vol.34
, pp. 396-402
-
-
Dyck, D.J.1
-
47
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
-
Eddahibi S, Hanoun N, Lanfumey L, Lesch KP, Raffestin B, Hamon M, Adnot S. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest 105: 1555-1562, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
Lesch, K.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
48
-
-
0036875182
-
Pulmonary hypertension associated with connective tissue disease
-
Fagan KA, Badesch DB. Pulmonary hypertension associated with connective tissue disease. Prog Cardiovasc Dis 45: 225-234, 2002.
-
(2002)
Prog Cardiovasc Dis
, vol.45
, pp. 225-234
-
-
Fagan, K.A.1
Badesch, D.B.2
-
49
-
-
0033694694
-
Nitric oxide synthase in pulmonary hypertension: Lessons from knockout mice
-
Fagan KA, Mc Murtry I, Rodman DM. Nitric oxide synthase in pulmonary hypertension: Lessons from knockout mice. Physiol Res 49: 539-548, 2000.
-
(2000)
Physiol Res
, vol.49
, pp. 539-548
-
-
Fagan, K.A.1
Mc Murtry, I.2
Rodman, D.M.3
-
50
-
-
0032887861
-
Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation
-
Fagan KA, Tyler RC, Sato K, Fouty BW, Morris KG, Jr., Huang PL, Mc Murtry IF, Rodman DM. Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation. Am J Physiol 277: L472-L478, 1999.
-
(1999)
Am J Physiol
, vol.277
-
-
Fagan, K.A.1
Tyler, R.C.2
Sato, K.3
Fouty, B.W.4
Morris Jr., K.G.5
Huang, P.L.6
McMurtry, I.F.7
Rodman, D.M.8
-
51
-
-
0028111604
-
Pulmonary hypertension and arterial changes in calves with a systemic-to-left pulmonary artery connection
-
Fasules JW, Tryka F, Chipman CW, Van Devanter SH. Pulmonary hypertension and arterial changes in calves with a systemic-to-left pulmonary artery connection. J Appl Physiol 77: 867-875, 1994.
-
(1994)
J Appl Physiol
, vol.77
, pp. 867-875
-
-
Fasules, J.W.1
Tryka, F.2
Chipman, C.W.3
Van Devanter, S.H.4
-
52
-
-
57149113351
-
Bringing down the ROS: A new therapeutic approach for PPHN
-
Firth AL, Yuan JX. Bringing down the ROS: A new therapeutic approach for PPHN. AmJ Physiol Lung Cell Mol Physiol 295: L976-L978, 2008.
-
(2008)
AmJ Physiol Lung Cell Mol Physiol
, vol.295
-
-
Firth, A.L.1
Yuan, J.X.2
-
53
-
-
24744471858
-
Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension
-
Frank DB, Abtahi A, Yamaguchi DJ, Manning S, Shyr Y, Pozzi A, Baldwin HS, Johnson JE, de Caestecker MP. Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension. Circ Res 97: 496-504, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 496-504
-
-
Frank, D.B.1
Abtahi, A.2
Yamaguchi, D.J.3
Manning, S.4
Shyr, Y.5
Pozzi, A.6
Baldwin, H.S.7
Johnson, J.E.8
de Caestecker, M.P.9
-
54
-
-
40749102181
-
Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature
-
Frank DB, Lowery J, Anderson L, Brink M, Reese J, de Caestecker M. Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature. Am J Physiol Lung Cell Mol Physiol 294: L98-L109, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Frank, D.B.1
Lowery, J.2
Anderson, L.3
Brink, M.4
Reese, J.5
de Caestecker, M.6
-
55
-
-
0034655765
-
The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice
-
Fujimura M, Morita-Fujimura Y, Noshita N, Sugawara T, Kawase M, Chan PH. The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J Neurosci 20: 2817-2824, 2000.
-
(2000)
J Neurosci
, vol.20
, pp. 2817-2824
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Noshita, N.3
Sugawara, T.4
Kawase, M.5
Chan, P.H.6
-
56
-
-
0036893519
-
Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression
-
Fujita M, Mason RJ, Cool C, Shannon JM, Hara N, Fagan KA. Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression. J Appl Physiol 93: 2162-2170, 2002.
-
(2002)
J Appl Physiol
, vol.93
, pp. 2162-2170
-
-
Fujita, M.1
Mason, R.J.2
Cool, C.3
Shannon, J.M.4
Hara, N.5
Fagan, K.A.6
-
57
-
-
30144444546
-
Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice
-
Golembeski SM, West J, Tada Y, Fagan KA. Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice. Chest 128: 572S-573S, 2005.
-
(2005)
Chest
, vol.128
-
-
Golembeski, S.M.1
West, J.2
Tada, Y.3
Fagan, K.A.4
-
58
-
-
37549066364
-
Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice
-
Goto H, Nishikawa T, Sonoda K, Kondo T, Kukidome D, Fujisawa K, Yamashiro T, Motoshima H, Matsumura T, Tsuruzoe K, Araki E. Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice. Biochem Biophys Res Commun 366: 814-820, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 814-820
-
-
Goto, H.1
Nishikawa, T.2
Sonoda, K.3
Kondo, T.4
Kukidome, D.5
Fujisawa, K.6
Yamashiro, T.7
Motoshima, H.8
Matsumura, T.9
Tsuruzoe, K.10
Araki, E.11
-
59
-
-
58149092723
-
VIP, from gene to behavior and back: Summarizing my 25 years of research
-
Gozes I. VIP, from gene to behavior and back: Summarizing my 25 years of research. J Mol Neurosci 36: 115-124, 2008.
-
(2008)
J Mol Neurosci
, vol.36
, pp. 115-124
-
-
Gozes, I.1
-
60
-
-
1542784420
-
S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy
-
Greenway S, van Suylen RJ, Du Marchie Sarvaas G, Kwan E, Ambartsumian N, Lukanidin E, Rabinovitch M. S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy. Am J Pathol 164: 253-262, 2004.
-
(2004)
Am J Pathol
, vol.164
, pp. 253-262
-
-
Greenway, S.1
van Suylen, R.J.2
Du Marchie Sarvaas, G.3
Kwan, E.4
Ambartsumian, N.5
Lukanidin, E.6
Rabinovitch, M.7
-
61
-
-
33744970745
-
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
-
Guignabert C, Izikki M, Tu LI, Li Z, Zadigue P, Barlier-Mur AM, Hanoun N, Rodman D, Hamon M, Adnot S, Eddahibi S. Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res 98: 1323-1330, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 1323-1330
-
-
Guignabert, C.1
Izikki, M.2
Tu, L.I.3
Li, Z.4
Zadigue, P.5
Barlier-Mur, A.M.6
Hanoun, N.7
Rodman, D.8
Hamon, M.9
Adnot, S.10
Eddahibi, S.11
-
62
-
-
34447534205
-
Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle
-
Hagen M, Fagan K, Steudel W, Carr M, Lane K, Rodman DM, West J. Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle. Am J Physiol Lung Cell Mol Physiol 292: L1473-1479, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Hagen, M.1
Fagan, K.2
Steudel, W.3
Carr, M.4
Lane, K.5
Rodman, D.M.6
West, J.7
-
63
-
-
0033779692
-
Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension
-
Hampl V, Herget J. Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension. Physiol Rev 80: 1337-1372, 2000.
-
(2000)
Physiol Rev
, vol.80
, pp. 1337-1372
-
-
Hampl, V.1
Herget, J.2
-
64
-
-
2342613573
-
Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: A model of alveolar capillary dysplasia?
-
Han RN, Babaei S, Robb M, Lee T, Ridsdale R, Ackerley C, Post M, Stewart DJ. Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: A model of alveolar capillary dysplasia? Circ Res 94: 1115-1123, 2004.
-
(2004)
Circ Res
, vol.94
, pp. 1115-1123
-
-
Han, R.N.1
Babaei, S.2
Robb, M.3
Lee, T.4
Ridsdale, R.5
Ackerley, C.6
Post, M.7
Stewart, D.J.8
-
65
-
-
68049102318
-
Pulmonary arterial hypertension complicating connective tissue diseases
-
Hassoun PM. Pulmonary arterial hypertension complicating connective tissue diseases. Semin Respir Crit Care Med 30: 429-439, 2009.
-
(2009)
Semin Respir Crit Care Med
, vol.30
, pp. 429-439
-
-
Hassoun, P.M.1
-
66
-
-
40749090043
-
PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation
-
Hemnes AR, Zaiman A, Champion HC. PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation. Am J Physiol Lung Cell Mol Physiol 294: L24-L33, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Hemnes, A.R.1
Zaiman, A.2
Champion, H.C.3
-
67
-
-
50349096148
-
Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension
-
Hong KH, Lee YJ, Lee E, Park SO, Han C, Beppu H, Li E, Raizada MK, Bloch KD, Oh SP. Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation 118: 722-730, 2008.
-
(2008)
Circulation
, vol.118
, pp. 722-730
-
-
Hong, K.H.1
Lee, Y.J.2
Lee, E.3
Park, S.O.4
Han, C.5
Beppu, H.6
Li, E.7
Raizada, M.K.8
Bloch, K.D.9
Oh, S.P.10
-
68
-
-
0034925219
-
Chronic airway infection leads to angiogenesis in the pulmonary circulation
-
Hopkins N, Cadogan E, Giles S, Mc Loughlin P. Chronic airway infection leads to angiogenesis in the pulmonary circulation. J Appl Physiol 91: 919-928, 2001.
-
(2001)
J Appl Physiol
, vol.91
, pp. 919-928
-
-
Hopkins, N.1
Cadogan, E.2
Giles, S.3
Mc Loughlin, P.4
-
69
-
-
0141705757
-
Hypoxia induces different genes in the lungs of rats compared with mice
-
Hoshikawa Y, Nana-Sinkam P, Moore MD, Sotto-Santiago S, Phang T, Keith RL, Morris KG, Kondo T, Tuder RM, Voelkel NF, Geraci MW. Hypoxia induces different genes in the lungs of rats compared with mice. Physiol Genomics 12: 209-219, 2003.
-
(2003)
Physiol Genomics
, vol.12
, pp. 209-219
-
-
Hoshikawa, Y.1
Nana-Sinkam, P.2
Moore, M.D.3
Sotto-Santiago, S.4
Phang, T.5
Keith, R.L.6
Morris, K.G.7
Kondo, T.8
Tuder, R.M.9
Voelkel, N.F.10
Geraci, M.W.11
-
70
-
-
0028639196
-
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
-
Hosoda K, Hammer RE, Richardson JA, Baynash AG, Cheung JC, Giaid A, Yanagisawa M. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice. Cell 79: 1267-1276, 1994.
-
(1994)
Cell
, vol.79
, pp. 1267-1276
-
-
Hosoda, K.1
Hammer, R.E.2
Richardson, J.A.3
Baynash, A.G.4
Cheung, J.C.5
Giaid, A.6
Yanagisawa, M.7
-
71
-
-
0029021148
-
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
-
Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377: 239-242, 1995.
-
(1995)
Nature
, vol.377
, pp. 239-242
-
-
Huang, P.L.1
Huang, Z.2
Mashimo, H.3
Bloch, K.D.4
Moskowitz, M.A.5
Bevan, J.A.6
Fishman, M.C.7
-
72
-
-
0036839051
-
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats
-
Ikeda Y, Yonemitsu Y, Kataoka C, Kitamoto S, Yamaoka T, Nishida K, Takeshita A, Egashira K, Sueishi K. Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats. Am J Physiol Heart Circ Physiol 283: H2021-2028, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Ikeda, Y.1
Yonemitsu, Y.2
Kataoka, C.3
Kitamoto, S.4
Yamaoka, T.5
Nishida, K.6
Takeshita, A.7
Egashira, K.8
Sueishi, K.9
-
73
-
-
35348842184
-
Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: Effects on hypoxic pulmonary hypertension in mice
-
Izikki M, Hanoun N, Marcos E, Savale L, Barlier-Mur AM, Saurini F, Eddahibi S, Hamon M, Adnot S. Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: Effects on hypoxic pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol 293: L1045-1052, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Izikki, M.1
Hanoun, N.2
Marcos, E.3
Savale, L.4
Barlier-Mur, A.M.5
Saurini, F.6
Eddahibi, S.7
Hamon, M.8
Adnot, S.9
-
75
-
-
0037235033
-
Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion
-
Jones SP, Hoffmeyer MR, Sharp BR, Ho YS, Lefer DJ. Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 284: H277-282, 2003.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Jones, S.P.1
Hoffmeyer, M.R.2
Sharp, B.R.3
Ho, Y.S.4
Lefer, D.J.5
-
76
-
-
0041508798
-
Systemic arteriovenous fistula leads to pulmonary artery remodeling and abnormal vasoreactivity in the fetal lamb
-
Jouannic JM, Roussin R, Hislop AA, Lanone S, Martinovic J, Boczkowski J, Dumez Y, Dinh-Xuan AT. Systemic arteriovenous fistula leads to pulmonary artery remodeling and abnormal vasoreactivity in the fetal lamb. Am J Physiol Lung Cell Mol Physiol 285: L701-L709, 2003.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Jouannic, J.M.1
Roussin, R.2
Hislop, A.A.3
Lanone, S.4
Martinovic, J.5
Boczkowski, J.6
Dumez, Y.7
Dinh-Xuan, A.T.8
-
77
-
-
0014061764
-
Pulmonary hypertension produced in rats by ingestion of Crotalaria spectabilis seeds
-
Kay JM, Harris P, Heath D. Pulmonary hypertension produced in rats by ingestion of Crotalaria spectabilis seeds. Thorax 22: 176-179, 1967.
-
(1967)
Thorax
, vol.22
, pp. 176-179
-
-
Kay, J.M.1
Harris, P.2
Heath, D.3
-
78
-
-
0035824915
-
Contribution of the 5-HT(1B) receptor to hypoxia-induced pulmonary hypertension: Converging evidence using 5-HT(1B)-receptor knockout mice and the 5-HT(1B/1D)-receptor antagonist GR127935
-
Keegan A, Morecroft I, Smillie D, Hicks MN, Mac Lean MR. Contribution of the 5-HT(1B) receptor to hypoxia-induced pulmonary hypertension: Converging evidence using 5-HT(1B)-receptor knockout mice and the 5-HT(1B/1D)-receptor antagonist GR127935. Circ Res 89: 1231-1239, 2001.
-
(2001)
Circ Res
, vol.89
, pp. 1231-1239
-
-
Keegan, A.1
Morecroft, I.2
Smillie, D.3
Hicks, M.N.4
Mac Lean, M.R.5
-
79
-
-
1842831283
-
Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers
-
Kho AT, Zhao Q, Cai Z, Butte AJ, Kim JY, Pomeroy SL, Rowitch DH, Kohane IS. Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes Dev 18: 629-640, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 629-640
-
-
Kho, A.T.1
Zhao, Q.2
Cai, Z.3
Butte, A.J.4
Kim, J.Y.5
Pomeroy, S.L.6
Rowitch, D.H.7
Kohane, I.S.8
-
80
-
-
17744386526
-
Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension
-
Khoo JP, Zhao L, Alp NJ, Bendall JK, Nicoli T, Rockett K, Wilkins MR, Channon KM. Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension. Circulation 111: 2126-2133, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2126-2133
-
-
Khoo, J.P.1
Zhao, L.2
Alp, N.J.3
Bendall, J.K.4
Nicoli, T.5
Rockett, K.6
Wilkins, M.R.7
Channon, K.M.8
-
81
-
-
33644683065
-
Adiponectin inhibits endothelial synthesis of interleukin-8
-
Kobashi C, Urakaze M, Kishida M, Kibayashi E, Kobayashi H, Kihara S, Funahashi T, Takata M, Temaru R, Sato A, Yamazaki K, Nakamura N, Kobayashi M. Adiponectin inhibits endothelial synthesis of interleukin-8. Circ Res 97: 1245-1252, 2005.
-
(2005)
Circ Res
, vol.97
, pp. 1245-1252
-
-
Kobashi, C.1
Urakaze, M.2
Kishida, M.3
Kibayashi, E.4
Kobayashi, H.5
Kihara, S.6
Funahashi, T.7
Takata, M.8
Temaru, R.9
Sato, A.10
Yamazaki, K.11
Nakamura, N.12
Kobayashi, M.13
-
82
-
-
0028360062
-
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin
-
Kurihara Y, Kurihara H, Suzuki H, Kodama T, Maemura K, Nagai R, Oda H, Kuwaki T, Cao WH, Kamada N, and et al. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin- Nature 368: 703-710, 1994.
-
(1994)
Nature
, vol.368
, pp. 703-710
-
-
Kurihara, Y.1
Kurihara, H.2
Suzuki, H.3
Kodama, T.4
Maemura, K.5
Nagai, R.6
Oda, H.7
Kuwaki, T.8
Cao, W.H.9
Kamada, N.10
-
83
-
-
19444378925
-
Effect of sustained hypobaric hypoxia during maturation and aging on rat myocardium. I. Mechanical activity
-
La Padula P, Costa LE. Effect of sustained hypobaric hypoxia during maturation and aging on rat myocardium. I. Mechanical activity. J Appl Physiol 98: 2363-2369, 2005.
-
(2005)
J Appl Physiol
, vol.98
, pp. 2363-2369
-
-
La Padula, P.1
Costa, L.E.2
-
84
-
-
0344666398
-
Monocrotaline-induced pulmonary arteritis in rats
-
Lalich JJ, Ehrhart LA. Monocrotaline-induced pulmonary arteritis in rats. J Atheroscler Res 2: 482-492, 1962.
-
(1962)
J Atheroscler Res
, vol.2
, pp. 482-492
-
-
Lalich, J.J.1
Ehrhart, L.A.2
-
85
-
-
66149164443
-
Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo
-
Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE. Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo. Clin Cancer Res 15: 3265-3276, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3265-3276
-
-
Landskroner-Eiger, S.1
Qian, B.2
Muise, E.S.3
Nawrocki, A.R.4
Berger, J.P.5
Fine, E.J.6
Koba, W.7
Deng, Y.8
Pollard, J.W.9
Scherer, P.E.10
-
86
-
-
0033817459
-
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
-
Lane KB, Machado RD, Pauciulo MW, Thomson JR, Phillips JA III, Loyd JE, Nichols WC, Trembath RC. Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. Nat Genet 26: 81-84, 2000.
-
(2000)
Nat Genet
, vol.26
, pp. 81-84
-
-
Lane, K.B.1
Machado, R.D.2
Pauciulo, M.W.3
Thomson, J.R.4
Phillips III, J.A.5
Loyd, J.E.6
Nichols, W.C.7
Trembath, R.C.8
-
87
-
-
58849114113
-
Inhalation of vasoactive intestinal peptide in pulmonary hypertension
-
Leuchte HH, Baezner C, Baumgartner RA, Bevec D, Bacher G, Neurohr C, Behr J. Inhalation of vasoactive intestinal peptide in pulmonary hypertension. Eur Respir J 32: 1289-1294, 2008.
-
(2008)
Eur Respir J
, vol.32
, pp. 1289-1294
-
-
Leuchte, H.H.1
Baezner, C.2
Baumgartner, R.A.3
Bevec, D.4
Bacher, G.5
Neurohr, C.6
Behr, J.7
-
88
-
-
33846304703
-
Inhibition of Rho kinase attenuates high flow induced pulmonary hypertension in rats
-
Li FH, Xia W, Li AW, Zhao CF, Sun RP. Inhibition of Rho kinase attenuates high flow induced pulmonary hypertension in rats. Chin Med J (Engl) 120: 22-29, 2007.
-
(2007)
Chin Med J (Engl)
, vol.120
, pp. 22-29
-
-
Li, F.H.1
Xia, W.2
Li, A.W.3
Zhao, C.F.4
Sun, R.P.5
-
89
-
-
33744931917
-
The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA
-
Li ZH, Bresnick AR. The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA. Cancer Res 66: 5173-5180, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 5173-5180
-
-
Li, Z.H.1
Bresnick, A.R.2
-
90
-
-
34548853386
-
Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity
-
Liu D, Wang J, Kinzel B, Mueller M, Mao X, Valdez R, Liu Y, Li E. Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity. Blood 110: 1502-1510, 2007.
-
(2007)
Blood
, vol.110
, pp. 1502-1510
-
-
Liu, D.1
Wang, J.2
Kinzel, B.3
Mueller, M.4
Mao, X.5
Valdez, R.6
Liu, Y.7
Li, E.8
-
91
-
-
33645751955
-
Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice
-
Long L, Mac Lean MR, Jeffery TK, Morecroft I, Yang X, Rudarakanchana N, Southwood M, James V, Trembath RC, Morrell NW. Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice. Circ Res 98: 818-827, 2006.
-
(2006)
Circ Res
, vol.98
, pp. 818-827
-
-
Long, L.1
Mac Lean, M.R.2
Jeffery, T.K.3
Morecroft, I.4
Yang, X.5
Rudarakanchana, N.6
Southwood, M.7
James, V.8
Trembath, R.C.9
Morrell, N.W.10
-
92
-
-
34547472539
-
Pulmonary hypertension and the serotonin hypothesis: Where are we now?
-
Mac Lean MR. Pulmonary hypertension and the serotonin hypothesis: Where are we now? Int J Clin Pract Suppl 156: 27-31, 2007.
-
(2007)
Int J Clin Pract Suppl
, vol.156
, pp. 27-31
-
-
Mac Lean, M.R.1
-
93
-
-
2442519344
-
Overexpression of the 5-hydroxytryptamine transporter gene: Effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension
-
Mac Lean MR, Deuchar GA, Hicks MN, Morecroft I, Shen S, Sheward J, Colston J, Loughlin L, Nilsen M, Dempsie Y, Harmar A. Overexpression of the 5-hydroxytryptamine transporter gene: Effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension. Circulation 109: 2150-2155, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2150-2155
-
-
Mac Lean, M.R.1
Deuchar, G.A.2
Hicks, M.N.3
Morecroft, I.4
Shen, S.5
Sheward, J.6
Colston, J.7
Loughlin, L.8
Nilsen, M.9
Dempsie, Y.10
Harmar, A.11
-
94
-
-
77951239891
-
Rho kinase-mediated vasoconstriction in pulmonary hypertension
-
Mc Murtry IF, Abe K, Ota H, Fagan KA, Oka M. Rho kinase-mediated vasoconstriction in pulmonary hypertension. Adv Exp Med Biol 661: 299-308, 2010.
-
(2010)
Adv Exp Med Biol
, vol.661
, pp. 299-308
-
-
Mc Murtry, I.F.1
Abe, K.2
Ota, H.3
Fagan, K.A.4
Oka, M.5
-
95
-
-
39149145493
-
Acute vasodilator effects of Rhokinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide
-
Mc Namara PJ, Murthy P, Kantores C, Teixeira L, Engelberts D, van Vliet T, Kavanagh BP, Jankov RP. Acute vasodilator effects of Rhokinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol 294: L205-213, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Mc Namara, P.J.1
Murthy, P.2
Kantores, C.3
Teixeira, L.4
Engelberts, D.5
van Vliet, T.6
Kavanagh, B.P.7
Jankov, R.P.8
-
96
-
-
70349160768
-
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling
-
Medoff BD, Okamoto Y, Leyton P, Weng M, Sandall BP, Raher MJ, Kihara S, Bloch KD, Libby P, Luster AD. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol 41: 397-406, 2009.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 397-406
-
-
Medoff, B.D.1
Okamoto, Y.2
Leyton, P.3
Weng, M.4
Sandall, B.P.5
Raher, M.J.6
Kihara, S.7
Bloch, K.D.8
Libby, P.9
Luster, A.D.10
-
97
-
-
35348969860
-
Serotonin modulates the cytokine network in the lung: Involvement of prostaglandin E2
-
Menard G, Turmel V, Bissonnette EY. Serotonin modulates the cytokine network in the lung: Involvement of prostaglandin E2. Clin Exp Immunol 150: 340-348, 2007.
-
(2007)
Clin Exp Immunol
, vol.150
, pp. 340-348
-
-
Menard, G.1
Turmel, V.2
Bissonnette, E.Y.3
-
98
-
-
0019082316
-
Development of Crotalaria pulmonary hypertension: Hemodynamic and structural study
-
Meyrick B, Gamble W, Reid L. Development of Crotalaria pulmonary hypertension: Hemodynamic and structural study. Am J Physiol 239: H692-702, 1980.
-
(1980)
Am J Physiol
, vol.239
-
-
Meyrick, B.1
Gamble, W.2
Reid, L.3
-
99
-
-
0018824798
-
Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression
-
Meyrick B, Reid L. Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression. Am J Pathol 100: 151-178, 1980.
-
(1980)
Am J Pathol
, vol.100
, pp. 151-178
-
-
Meyrick, B.1
Reid, L.2
-
100
-
-
0024434805
-
The sequence of cellular and hemodynamic changes of chronic pulmonary hypertension induced by hypoxia and other stimuli
-
Meyrick BO, Perkett EA. The sequence of cellular and hemodynamic changes of chronic pulmonary hypertension induced by hypoxia and other stimuli. Am Rev Respir Dis 140: 1486-1489, 1989.
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 1486-1489
-
-
Meyrick, B.O.1
Perkett, E.A.2
-
101
-
-
0034018782
-
Athymic nude rats develop severe pulmonary hypertension following monocrotaline administration
-
Miyata M, Sakuma F, Ito M, Ohira H, Sato Y, Kasukawa R. Athymic nude rats develop severe pulmonary hypertension following monocrotaline administration. Int Arch Allergy Immunol 121: 246-252, 2000.
-
(2000)
Int Arch Allergy Immunol
, vol.121
, pp. 246-252
-
-
Miyata, M.1
Sakuma, F.2
Ito, M.3
Ohira, H.4
Sato, Y.5
Kasukawa, R.6
-
102
-
-
0028861014
-
Pulmonary hypertension in rats. 2. Role of interleukin-6
-
Miyata M, Sakuma F, Yoshimura A, Ishikawa H, Nishimaki T, Kasukawa R. Pulmonary hypertension in rats. 2. Role of interleukin-6. Int Arch Allergy Immunol 108: 287-291, 1995.
-
(1995)
Int Arch Allergy Immunol
, vol.108
, pp. 287-291
-
-
Miyata, M.1
Sakuma, F.2
Yoshimura, A.3
Ishikawa, H.4
Nishimaki, T.5
Kasukawa, R.6
-
104
-
-
0032762332
-
Disruption of ET-1 gene enhances pulmonary responses to methacholine via functional mechanism in knockout mice
-
Nagase T, Kurihara H, Kurihara Y, Aoki-Nagase T, Nagai R, Ouchi Y. Disruption of ET-1 gene enhances pulmonary responses to methacholine via functional mechanism in knockout mice. J Appl Physiol 87: 2020-2024, 1999.
-
(1999)
J Appl Physiol
, vol.87
, pp. 2020-2024
-
-
Nagase, T.1
Kurihara, H.2
Kurihara, Y.3
Aoki-Nagase, T.4
Nagai, R.5
Ouchi, Y.6
-
105
-
-
63149113296
-
Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling
-
Nakagawa Y, Kishida K, Kihara S, Funahashi T, Shimomura I. Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling. Biochem Biophys Res Commun 382: 183-188, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 183-188
-
-
Nakagawa, Y.1
Kishida, K.2
Kihara, S.3
Funahashi, T.4
Shimomura, I.5
-
106
-
-
17744381754
-
Pulmonary hypertension in aGTP-cyclohydrolase 1-deficient mouse
-
Nandi M, Miller A, Stidwill R, Jacques TS, Lam AA, Haworth S, Heales S, Vallance P. Pulmonary hypertension in aGTP-cyclohydrolase 1-deficient mouse. Circulation 111: 2086-2090, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2086-2090
-
-
Nandi, M.1
Miller, A.2
Stidwill, R.3
Jacques, T.S.4
Lam, A.A.5
Haworth, S.6
Heales, S.7
Vallance, P.8
-
107
-
-
32444445247
-
Pleiotropic contributions of nitric oxide to aggressive behavior
-
Nelson RJ, Trainor BC, Chiavegatto S, Demas GE. Pleiotropic contributions of nitric oxide to aggressive behavior. Neurosci Biobehav Rev 30: 346-355, 2006.
-
(2006)
Neurosci Biobehav Rev
, vol.30
, pp. 346-355
-
-
Nelson, R.J.1
Trainor, B.C.2
Chiavegatto, S.3
Demas, G.E.4
-
108
-
-
3042511852
-
Pulmonary arterial hypertension: Future directions. Report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop
-
Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, Mc Goon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, Tuder RM, Voelkel NF, Gail DB. Pulmonary arterial hypertension: Future directions. Report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation 109: 2947-2952, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2947-2952
-
-
Newman, J.H.1
Fanburg, B.L.2
Archer, S.L.3
Badesch, D.B.4
Barst, R.J.5
Garcia, J.G.6
Kao, P.N.7
Knowles, J.A.8
Loyd, J.E.9
Mc Goon, M.D.10
Morse, J.H.11
Nichols, W.C.12
Rabinovitch, M.13
Rodman, D.M.14
Stevens, T.15
Tuder, R.M.16
Voelkel, N.F.17
Gail, D.B.18
-
109
-
-
52649119390
-
Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling
-
Nozik-Grayck E, Suliman HB, Majka S, Albietz J, Van Rheen Z, Roush K, Stenmark KR. Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol 295: L422-L430, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Nozik-Grayck, E.1
Suliman, H.B.2
Majka, S.3
Albietz, J.4
Van Rheen, Z.5
Roush, K.6
Stenmark, K.R.7
-
110
-
-
43349100844
-
Inhalation of stachybotrys chartarum causes pulmonary arterial hypertension in mice
-
Ochiai E, Kamei K, Watanabe A, Nagayoshi M, Tada Y, Nagaoka T, Sato K, Sato A, Shibuya K. Inhalation of stachybotrys chartarum causes pulmonary arterial hypertension in mice. Int J Exp Pathol 89: 201-208, 2008.
-
(2008)
Int J Exp Pathol
, vol.89
, pp. 201-208
-
-
Ochiai, E.1
Kamei, K.2
Watanabe, A.3
Nagayoshi, M.4
Tada, Y.5
Nagaoka, T.6
Sato, K.7
Sato, A.8
Shibuya, K.9
-
111
-
-
33744979305
-
Adiponectin replenishment ameliorates obesity-related hypertension
-
Ohashi K, Kihara S, Ouchi N, Kumada M, Fujita K, Hiuge A, Hibuse T, Ryo M, Nishizawa H, Maeda N, Maeda K, Shibata R, Walsh K, Funahashi T, Shimomura I. Adiponectin replenishment ameliorates obesity-related hypertension. Hypertension 47: 1108-1116, 2006.
-
(2006)
Hypertension
, vol.47
, pp. 1108-1116
-
-
Ohashi, K.1
Kihara, S.2
Ouchi, N.3
Kumada, M.4
Fujita, K.5
Hiuge, A.6
Hibuse, T.7
Ryo, M.8
Nishizawa, H.9
Maeda, N.10
Maeda, K.11
Shibata, R.12
Walsh, K.13
Funahashi, T.14
Shimomura, I.15
-
112
-
-
77949881805
-
Adiponectin promotes macrophage polarization towards an antiinflammatory phenotype
-
Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Amstrup Pedersen A, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization towards an antiinflammatory phenotype. J Biol Chem 285(9): 6153-6160, 2009.
-
(2009)
J Biol Chem
, vol.285
, Issue.9
, pp. 6153-6160
-
-
Ohashi, K.1
Parker, J.L.2
Ouchi, N.3
Higuchi, A.4
Vita, J.A.5
Gokce, N.6
Amstrup Pedersen, A.7
Kalthoff, C.8
Tullin, S.9
Sams, A.10
Summer, R.11
Walsh, K.12
-
113
-
-
0032535435
-
Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
-
Ohashi Y, Kawashima S, Hirata K, Yamashita T, Ishida T, Inoue N, Sakoda T, Kurihara H, Yazaki Y, Yokoyama M. Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. JClin Invest 102: 2061-2071, 1998.
-
(1998)
JClin Invest
, vol.102
, pp. 2061-2071
-
-
Ohashi, Y.1
Kawashima, S.2
Hirata, K.3
Yamashita, T.4
Ishida, T.5
Inoue, N.6
Sakoda, T.7
Kurihara, H.8
Yazaki, Y.9
Yokoyama, M.10
-
114
-
-
53849089211
-
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
-
Oka M, Fagan KA, Jones PL, Mc Murtry IF. Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension. Br J Pharmacol 155: 444-454, 2008.
-
(2008)
Br J Pharmacol
, vol.155
, pp. 444-454
-
-
Oka, M.1
Fagan, K.A.2
Jones, P.L.3
Mc Murtry, I.F.4
-
115
-
-
34147189502
-
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, Mc Murtry IF. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res 100: 923-929, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
Voelkel, N.F.7
Mc Murtry, I.F.8
-
116
-
-
0030828893
-
Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension
-
Okada K, Tanaka Y, Bernstein M, Zhang W, Patterson GA, Botney MD. Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension. Am J Pathol 151: 1019-1025, 1997.
-
(1997)
Am J Pathol
, vol.151
, pp. 1019-1025
-
-
Okada, K.1
Tanaka, Y.2
Bernstein, M.3
Zhang, W.4
Patterson, G.A.5
Botney, M.D.6
-
117
-
-
0347334429
-
Obesity, adiponectin and vascular inflammatory disease
-
Ouchi N, Kihara S, Funahashi T, Matsuzawa Y, Walsh K. Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol 14: 561-566, 2003.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 561-566
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
Matsuzawa, Y.4
Walsh, K.5
-
118
-
-
0034533016
-
Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats
-
Partovian C, Adnot S, Raffestin B, Louzier V, Levame M, Mavier IM, Lemarchand P, Eddahibi S. Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats. Am J Respir Cell Mol Biol 23: 762-771, 2000.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 762-771
-
-
Partovian, C.1
Adnot, S.2
Raffestin, B.3
Louzier, V.4
Levame, M.5
Mavier, I.M.6
Lemarchand, P.7
Eddahibi, S.8
-
119
-
-
44449120433
-
Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension
-
Phillips JA III, Poling JS, Phillips CA, Stanton KC, Austin ED, Cogan JD, Wheeler L, Yu C, Newman JH, Dietz HC, Loyd JE. Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension. Genet Med 10: 359-365, 2008.
-
(2008)
Genet Med
, vol.10
, pp. 359-365
-
-
Phillips III, J.A.1
Poling, J.S.2
Phillips, C.A.3
Stanton, K.C.4
Austin, E.D.5
Cogan, J.D.6
Wheeler, L.7
Yu, C.8
Newman, J.H.9
Dietz, H.C.10
Loyd, J.E.11
-
120
-
-
67650786508
-
Association of the metabolic syndrome with pulmonary venous hypertension
-
Robbins IM, Newman JH, Johnson RF, Hemnes AR, Fremont RD, Piana RN, Zhao DX, Byrne DW. Association of the metabolic syndrome with pulmonary venous hypertension. Chest 136: 31-36, 2009.
-
(2009)
Chest
, vol.136
, pp. 31-36
-
-
Robbins, I.M.1
Newman, J.H.2
Johnson, R.F.3
Hemnes, A.R.4
Fremont, R.D.5
Piana, R.N.6
Zhao, D.X.7
Byrne, D.W.8
-
121
-
-
74849100584
-
Novel Loci interacting epistatically with bone morphogenetic protein receptor 2 cause familial pulmonary arterial hypertension
-
Rodriguez-Murillo L, Subaran R, Stewart WC, Pramanik S, Marathe S, Barst RJ, Chung WK, Greenberg DA. Novel Loci interacting epistatically with bone morphogenetic protein receptor 2 cause familial pulmonary arterial hypertension. J Heart Lung Transplant 29(2): 174-180, 2010.
-
(2010)
J Heart Lung Transplant
, vol.29
, Issue.2
, pp. 174-180
-
-
Rodriguez-Murillo, L.1
Subaran, R.2
Stewart, W.C.3
Pramanik, S.4
Marathe, S.5
Barst, R.J.6
Chung, W.K.7
Greenberg, D.A.8
-
122
-
-
33644596212
-
A bonederived mixture of TGF beta-superfamily members forms a more mature vascular network than bFGF or TGF-beta 2 in vivo
-
Roedersheimer M, West J, Huffer W, Harral J, Benedict J. A bonederived mixture of TGF beta-superfamily members forms a more mature vascular network than bFGF or TGF-beta 2 in vivo. Angiogenesis 8: 327-338, 2005.
-
(2005)
Angiogenesis
, vol.8
, pp. 327-338
-
-
Roedersheimer, M.1
West, J.2
Huffer, W.3
Harral, J.4
Benedict, J.5
-
123
-
-
56649122070
-
The vasoactive intestinal peptide gene is a key modulator of pulmonary vascular remodeling and inflammation
-
Said SI. The vasoactive intestinal peptide gene is a key modulator of pulmonary vascular remodeling and inflammation. Ann N Y Acad Sci 1144: 148-153, 2008.
-
(2008)
Ann N Y Acad Sci
, vol.1144
, pp. 148-153
-
-
Said, S.I.1
-
124
-
-
33947721196
-
Moderate pulmonary arterial hypertension in male mice lacking the vasoactive intestinal peptide gene
-
Said SI, Hamidi SA, Dickman KG, Szema AM, Lyubsky S, Lin RZ, Jiang YP, Chen JJ, Waschek JA, Kort S. Moderate pulmonary arterial hypertension in male mice lacking the vasoactive intestinal peptide gene. Circulation 115: 1260-1268, 2007.
-
(2007)
Circulation
, vol.115
, pp. 1260-1268
-
-
Said, S.I.1
Hamidi, S.A.2
Dickman, K.G.3
Szema, A.M.4
Lyubsky, S.5
Lin, R.Z.6
Jiang, Y.P.7
Chen, J.J.8
Waschek, J.A.9
Kort, S.10
-
125
-
-
0042561843
-
Toxic oil syndrome: Survival in thewhole cohort between 1981 and 1995
-
Sanchez-Porro Valades P, Posada de la Paz M, de Andres Copa P, Gimenez Ribota O, Abaitua Borda I. Toxic oil syndrome: Survival in thewhole cohort between 1981 and 1995. JClin Epidemiol 56: 701-708, 2003.
-
(2003)
JClin Epidemiol
, vol.56
, pp. 701-708
-
-
Sanchez-Porro Valades, P.1
Posada de la Paz, M.2
de Andres Copa, P.3
Gimenez Ribota, O.4
Abaitua Borda, I.5
-
126
-
-
61549104663
-
Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
-
Savale L, Tu L, Rideau D, Izziki M, Maitre B, Adnot S, Eddahibi S. Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice. Respir Res 10: 6, 2009.
-
(2009)
Respir Res
, vol.10
, pp. 6
-
-
Savale, L.1
Tu, L.2
Rideau, D.3
Izziki, M.4
Maitre, B.5
Adnot, S.6
Eddahibi, S.7
-
127
-
-
0037870539
-
Normo- and hypobaric hypoxia: Are there any physiological differences?
-
Savourey G, Launay JC, Besnard Y, Guinet A, Travers S. Normo- and hypobaric hypoxia: Are there any physiological differences? Eur J Appl Physiol 89: 122-126, 2003.
-
(2003)
Eur J Appl Physiol
, vol.89
, pp. 122-126
-
-
Savourey, G.1
Launay, J.C.2
Besnard, Y.3
Guinet, A.4
Travers, S.5
-
128
-
-
34447536457
-
Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease
-
Schmidt TS, Alp NJ. Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease. Clin Sci (Lond) 113: 47-63, 2007.
-
(2007)
Clin Sci (Lond)
, vol.113
, pp. 47-63
-
-
Schmidt, T.S.1
Alp, N.J.2
-
129
-
-
74449089564
-
Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan
-
Schroll S, Arzt M, Sebah D, Nuchterlein M, Blumberg F, Pfeifer M. Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan. Respir Physiol Neurobiol 170(1): 32-36, 2010.
-
(2010)
Respir Physiol Neurobiol
, vol.170
, Issue.1
, pp. 32-36
-
-
Schroll, S.1
Arzt, M.2
Sebah, D.3
Nuchterlein, M.4
Blumberg, F.5
Pfeifer, M.6
-
130
-
-
0025782765
-
Early indications of monocrotaline pyrrole-induced lung injury in rats
-
Schultze AE, Wagner JG, White SM, Roth RA. Early indications of monocrotaline pyrrole-induced lung injury in rats. Toxicol Appl Pharmacol 109: 41-50, 1991.
-
(1991)
Toxicol Appl Pharmacol
, vol.109
, pp. 41-50
-
-
Schultze, A.E.1
Wagner, J.G.2
White, S.M.3
Roth, R.A.4
-
131
-
-
20144363889
-
Metastasis-associated protein S100A4 induces angiogenesis through interactionwith Annexin II and accelerated plasmin formation
-
Semov A, Moreno MJ, Onichtchenko A, Abulrob A, Ball M, Ekiel I, Pietrzynski G, Stanimirovic D, Alakhov V. Metastasis-associated protein S100A4 induces angiogenesis through interactionwith Annexin II and accelerated plasmin formation. J Biol Chem 280: 20833-20841, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 20833-20841
-
-
Semov, A.1
Moreno, M.J.2
Onichtchenko, A.3
Abulrob, A.4
Ball, M.5
Ekiel, I.6
Pietrzynski, G.7
Stanimirovic, D.8
Alakhov, V.9
-
132
-
-
33646344248
-
Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase
-
Sentman ML, Granstrom M, Jakobson H, Reaume A, Basu S, Marklund SL. Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase. J Biol Chem 281: 6904-6909, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 6904-6909
-
-
Sentman, M.L.1
Granstrom, M.2
Jakobson, H.3
Reaume, A.4
Basu, S.5
Marklund, S.L.6
-
133
-
-
0029995775
-
A comparison of pathophysiological changes during hypobaric and normobaric hypoxia in rats
-
Sheedy W, Thompson JS, Morice AH. A comparison of pathophysiological changes during hypobaric and normobaric hypoxia in rats. Respiration 63: 217-222, 1996.
-
(1996)
Respiration
, vol.63
, pp. 217-222
-
-
Sheedy, W.1
Thompson, J.S.2
Morice, A.H.3
-
134
-
-
69349105535
-
Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice
-
Shu RZ, Zhang F, Wang F, Feng DC, Li XH, Ren WH, Wu XL, Yang X, Liao XD, Huang L, Wang ZG. Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice. Lab Invest 89: 1043-1052, 2009.
-
(2009)
Lab Invest
, vol.89
, pp. 1043-1052
-
-
Shu, R.Z.1
Zhang, F.2
Wang, F.3
Feng, D.C.4
Li, X.H.5
Ren, W.H.6
Wu, X.L.7
Yang, X.8
Liao, X.D.9
Huang, L.10
Wang, Z.G.11
-
135
-
-
23044504042
-
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
-
Song Y, Jones JE, Beppu H, Keaney JF, Jr., Loscalzo J, Zhang YY. Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation 112: 553-562, 2005.
-
(2005)
Circulation
, vol.112
, pp. 553-562
-
-
Song, Y.1
Jones, J.E.2
Beppu, H.3
Keaney Jr., J.F.4
Loscalzo, J.5
Zhang, Y.Y.6
-
136
-
-
0345707647
-
Regulatory effects of iNOS on acute lung inflammatory responses in mice
-
Speyer CL, Neff TA, Warner RL, Guo RF, Sarma JV, Riedemann NC, Murphy ME, Murphy HS, Ward PA. Regulatory effects of iNOS on acute lung inflammatory responses in mice. Am J Pathol 163: 2319-2328, 2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 2319-2328
-
-
Speyer, C.L.1
Neff, T.A.2
Warner, R.L.3
Guo, R.F.4
Sarma, J.V.5
Riedemann, N.C.6
Murphy, M.E.7
Murphy, H.S.8
Ward, P.A.9
-
137
-
-
70349659680
-
S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4
-
13 p following 647
-
Spiekerkoetter E, Guignabert C, de Jesus Perez V, Alastalo TP, Powers JM, Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. Circ Res 105: 639-647, 13 p following 647, 2009.
-
(2009)
Circ Res
, vol.105
, pp. 639-647
-
-
Spiekerkoetter, E.1
Guignabert, C.2
de Jesus Perez, V.3
Alastalo, T.P.4
Powers, J.M.5
Wang, L.6
Lawrie, A.7
Ambartsumian, N.8
Schmidt, A.M.9
Berryman, M.10
Ashley, R.H.11
Rabinovitch, M.12
-
138
-
-
0023203985
-
Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4. 300 m
-
Stenmark KR, Fasules J, Hyde DM, Voelkel NF, Henson J, Tucker A, Wilson H, Reeves JT. Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m. J Appl Physiol 62: 821-830, 1987.
-
(1987)
J Appl Physiol
, vol.62
, pp. 821-830
-
-
Stenmark, K.R.1
Fasules, J.2
Hyde, D.M.3
Voelkel, N.F.4
Henson, J.5
Tucker, A.6
Wilson, H.7
Reeves, J.T.8
-
139
-
-
71949129187
-
Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
-
Stenmark KR, Meyrick B, Galie N, Mooi WJ, Mc Murtry IF. Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol 297: L1013-1032, 2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Stenmark, K.R.1
Meyrick, B.2
Galie, N.3
Mooi, W.J.4
Mc Murtry, I.F.5
-
140
-
-
68949149049
-
Adiponectin deficiency: A model of pulmonary hypertension associated with pulmonary vascular disease
-
Summer R, Fiack CA, Ikeda Y, Sato K, Dwyer D, Ouchi N, Fine A, Farber HW, Walsh K. Adiponectin deficiency: A model of pulmonary hypertension associated with pulmonary vascular disease. Am J Physiol Lung Cell Mol Physiol 297: L432-438, 2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Summer, R.1
Fiack, C.A.2
Ikeda, Y.3
Sato, K.4
Dwyer, D.5
Ouchi, N.6
Fine, A.7
Farber, H.W.8
Walsh, K.9
-
141
-
-
48949119345
-
Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice
-
Summer R, Little FF, Ouchi N, Takemura Y, Aprahamian T, Dwyer D, Fitzsimmons K, Suki B, Parameswaran H, Fine A, Walsh K. Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice. Am J Physiol Lung Cell Mol Physiol 294: L1035-L1042, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Summer, R.1
Little, F.F.2
Ouchi, N.3
Takemura, Y.4
Aprahamian, T.5
Dwyer, D.6
Fitzsimmons, K.7
Suki, B.8
Parameswaran, H.9
Fine, A.10
Walsh, K.11
-
142
-
-
33751101864
-
Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP
-
Szema AM, Hamidi SA, Lyubsky S, Dickman KG, Mathew S, Abdel-Razek T, Chen JJ, Waschek JA, Said SI. Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP. Am J Physiol Lung Cell Mol Physiol 291: L880-L886, 2006.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Szema, A.M.1
Hamidi, S.A.2
Lyubsky, S.3
Dickman, K.G.4
Mathew, S.5
Abdel-Razek, T.6
Chen, J.J.7
Waschek, J.A.8
Said, S.I.9
-
143
-
-
46749104461
-
Murine pulmonary response to chronic hypoxia is strain specific
-
Tada Y, Laudi S, Harral J, Carr M, Ivester C, Tanabe N, Takiguchi Y, Tatsumi K, Kuriyama T, Nichols WC, West J. Murine pulmonary response to chronic hypoxia is strain specific. Exp Lung Res 34: 313-323, 2008.
-
(2008)
Exp Lung Res
, vol.34
, pp. 313-323
-
-
Tada, Y.1
Laudi, S.2
Harral, J.3
Carr, M.4
Ivester, C.5
Tanabe, N.6
Takiguchi, Y.7
Tatsumi, K.8
Kuriyama, T.9
Nichols, W.C.10
West, J.11
-
144
-
-
34447542025
-
Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH
-
Tada Y, Majka S, Carr M, Harral J, Crona D, Kuriyama T, West J. Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH. Am J Physiol Lung Cell Mol Physiol 292: L1556-L1563, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Tada, Y.1
Majka, S.2
Carr, M.3
Harral, J.4
Crona, D.5
Kuriyama, T.6
West, J.7
-
145
-
-
0033623296
-
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family
-
Thomson JR, Machado RD, Pauciulo MW, Morgan NV, Humbert M, Elliott GC, Ward K, Yacoub M, Mikhail G, Rogers P, Newman J, Wheeler L, Higenbottam T, Gibbs JS, Egan J, Crozier A, Peacock A, Allcock R, Corris P, Loyd JE, Trembath RC, Nichols WC. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. J Med Genet 37: 741-745, 2000.
-
(2000)
J Med Genet
, vol.37
, pp. 741-745
-
-
Thomson, J.R.1
Machado, R.D.2
Pauciulo, M.W.3
Morgan, N.V.4
Humbert, M.5
Elliott, G.C.6
Ward, K.7
Yacoub, M.8
Mikhail, G.9
Rogers, P.10
Newman, J.11
Wheeler, L.12
Higenbottam, T.13
Gibbs, J.S.14
Egan, J.15
Crozier, A.16
Peacock, A.17
Allcock, R.18
Corris, P.19
Loyd, J.E.20
Trembath, R.C.21
Nichols, W.C.22
more..
-
146
-
-
68149181704
-
2-Methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats
-
Tofovic SP, Zhang X, Jackson EK, Zhu H, Petrusevska G. 2-Methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats. Vascul Pharmacol 51: 190-197, 2009.
-
(2009)
Vascul Pharmacol
, vol.51
, pp. 190-197
-
-
Tofovic, S.P.1
Zhang, X.2
Jackson, E.K.3
Zhu, H.4
Petrusevska, G.5
-
147
-
-
71949130151
-
Inhaled nitric oxide improves lung structure and pulmonary hypertension in amodel of bleomycin-induced bronchopulmonary dysplasia in neonatal rats
-
Tourneux P, Markham N, Seedorf G, Balasubramaniam V, Abman SH. Inhaled nitric oxide improves lung structure and pulmonary hypertension in amodel of bleomycin-induced bronchopulmonary dysplasia in neonatal rats. Am J Physiol Lung Cell Mol Physiol 297: L1103-L1111, 2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Tourneux, P.1
Markham, N.2
Seedorf, G.3
Balasubramaniam, V.4
Abman, S.H.5
-
148
-
-
0015363070
-
Studies on the mechanism of antitumor effect of bleomycin of squamous cell carcinoma
-
Umezawa H, Takeuchi T, Hori S, Sawa T, Ishizuka M. Studies on the mechanism of antitumor effect of bleomycin of squamous cell carcinoma. J Antibiot (Tokyo) 25: 409-420, 1972.
-
(1972)
J Antibiot (Tokyo)
, vol.25
, pp. 409-420
-
-
Umezawa, H.1
Takeuchi, T.2
Hori, S.3
Sawa, T.4
Ishizuka, M.5
-
149
-
-
3142722666
-
Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats
-
Vaszar LT, Nishimura T, Storey JD, Zhao G, Qiu D, Faul JL, Pearl RG, Kao PN. Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats. Physiol Genomics 17: 150-156, 2004.
-
(2004)
Physiol Genomics
, vol.17
, pp. 150-156
-
-
Vaszar, L.T.1
Nishimura, T.2
Storey, J.D.3
Zhao, G.4
Qiu, D.5
Faul, J.L.6
Pearl, R.G.7
Kao, P.N.8
-
150
-
-
55249096739
-
From viral infection to pulmonary arterial hypertension: A role for viral proteins?
-
Voelkel NF, Cool CD, Flores S. From viral infection to pulmonary arterial hypertension: A role for viral proteins? AIDS 22 Suppl 3: S49-S53, 2008.
-
(2008)
AIDS
, vol.22
, Issue.SUPPL. 3
-
-
Voelkel, N.F.1
Cool, C.D.2
Flores, S.3
-
151
-
-
0001710811
-
Vasoconstriction and medial hypertrophy in pulmonary hypertension
-
Wagenvoort CA. Vasoconstriction and medial hypertrophy in pulmonary hypertension. Circulation 22: 535-546, 1960.
-
(1960)
Circulation
, vol.22
, pp. 535-546
-
-
Wagenvoort, C.A.1
-
152
-
-
2342486700
-
Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle
-
West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R, Rodman DM. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res 94: 1109-1114, 2004.
-
(2004)
Circ Res
, vol.94
, pp. 1109-1114
-
-
West, J.1
Fagan, K.2
Steudel, W.3
Fouty, B.4
Lane, K.5
Harral, J.6
Hoedt-Miller, M.7
Tada, Y.8
Ozimek, J.9
Tuder, R.10
Rodman, D.M.11
-
153
-
-
57049159708
-
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions
-
West J, Harral J, Lane K, Deng Y, Ickes B, Crona D, Albu S, Stewart D, Fagan K. Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. Am J Physiol Lung Cell Mol Physiol 295: L744-L755, 2008.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
West, J.1
Harral, J.2
Lane, K.3
Deng, Y.4
Ickes, B.5
Crona, D.6
Albu, S.7
Stewart, D.8
Fagan, K.9
-
154
-
-
0027062783
-
Mechanisms and pathology of monocrotaline pulmonary toxicity
-
Wilson DW, Segall HJ, Pan LC, Lame MW, Estep JE, Morin D. Mechanisms and pathology of monocrotaline pulmonary toxicity. Crit Rev Toxicol 22: 307-325, 1992.
-
(1992)
Crit Rev Toxicol
, vol.22
, pp. 307-325
-
-
Wilson, D.W.1
Segall, H.J.2
Pan, L.C.3
Lame, M.W.4
Estep, J.E.5
Morin, D.6
-
155
-
-
43049126174
-
Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice
-
Wunderlich C, Schmeisser A, Heerwagen C, Ebner B, Schober K, Braun-Dullaeus RC, Schwencke C, Kasper M, Morawietz H, Strasser RH. Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice. Pulm Pharmacol Ther 21: 507-515, 2008.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 507-515
-
-
Wunderlich, C.1
Schmeisser, A.2
Heerwagen, C.3
Ebner, B.4
Schober, K.5
Braun-Dullaeus, R.C.6
Schwencke, C.7
Kasper, M.8
Morawietz, H.9
Strasser, R.H.10
-
156
-
-
33846614655
-
Alterations of cellular bioenergetics in pulmonary artery endothelial cells
-
Xu W, Koeck T, Lara AR, Neumann D, Di Filippo FP, Koo M, Janocha AJ, Masri FA, Arroliga AC, Jennings C, Dweik RA, Tuder RM, Stuehr DJ, Erzurum SC. Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A 104: 1342-1347, 2007.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1342-1347
-
-
Xu, W.1
Koeck, T.2
Lara, A.R.3
Neumann, D.4
Di Filippo, F.P.5
Koo, M.6
Janocha, A.J.7
Masri, F.A.8
Arroliga, A.C.9
Jennings, C.10
Dweik, R.A.11
Tuder, R.M.12
Stuehr, D.J.13
Erzurum, S.C.14
-
157
-
-
33749331604
-
Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products
-
Yammani RR, Carlson CS, Bresnick AR, Loeser RF. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis Rheum 54: 2901-2911, 2006.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2901-2911
-
-
Yammani, R.R.1
Carlson, C.S.2
Bresnick, A.R.3
Loeser, R.F.4
-
158
-
-
0031940499
-
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene
-
Yanagisawa H, Yanagisawa M, Kapur RP, Richardson JA, Williams SC, Clouthier DE, deWit D, Emoto N, Hammer RE. Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development 125: 825-836, 1998.
-
(1998)
Development
, vol.125
, pp. 825-836
-
-
Yanagisawa, H.1
Yanagisawa, M.2
Kapur, R.P.3
Richardson, J.A.4
Williams, S.C.5
Clouthier, D.E.6
deWit, D.7
Emoto, N.8
Hammer, R.E.9
-
159
-
-
63549125875
-
The antioxidative effect of bone morphogenetic protein-7 against high glucose-induced oxidative stress in mesangial cells
-
Yeh CH, Chang CK, Cheng MF, Lin HJ, Cheng JT. The antioxidative effect of bone morphogenetic protein-7 against high glucose-induced oxidative stress in mesangial cells. Biochem Biophys Res Commun 382: 292-297, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 292-297
-
-
Yeh, C.H.1
Chang, C.K.2
Cheng, M.F.3
Lin, H.J.4
Cheng, J.T.5
-
160
-
-
33646593842
-
BMP signaling controls PASMC KV channel expression in vitro and in vivo
-
Young KA, Ivester C, West J, Carr M, Rodman DM. BMP signaling controls PASMC KV channel expression in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol 290: L841-L848, 2006.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Young, K.A.1
Ivester, C.2
West, J.3
Carr, M.4
Rodman, D.M.5
-
161
-
-
21644447416
-
Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells
-
Yu PB, Beppu H, Kawai N, Li E, Bloch KD. Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells. J Biol Chem 280: 24443-24450, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 24443-24450
-
-
Yu, P.B.1
Beppu, H.2
Kawai, N.3
Li, E.4
Bloch, K.D.5
-
162
-
-
66349095797
-
A functional singlenucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension
-
Yu Y, Keller SH, Remillard CV, Safrina O, Nicholson A, Zhang SL, Jiang W, Vangala N, Landsberg JW, Wang JY, Thistlethwaite PA, Channick RN, Robbins IM, Loyd JE, Ghofrani HA, Grimminger F, Schermuly RT, Cahalan MD, Rubin LJ, Yuan JX. A functional singlenucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation 119: 2313-2322, 2009.
-
(2009)
Circulation
, vol.119
, pp. 2313-2322
-
-
Yu, Y.1
Keller, S.H.2
Remillard, C.V.3
Safrina, O.4
Nicholson, A.5
Zhang, S.L.6
Jiang, W.7
Vangala, N.8
Landsberg, J.W.9
Wang, J.Y.10
Thistlethwaite, P.A.11
Channick, R.N.12
Robbins, I.M.13
Loyd, J.E.14
Ghofrani, H.A.15
Grimminger, F.16
Schermuly, R.T.17
Cahalan, M.D.18
Rubin, L.J.19
Yuan, J.X.20
more..
-
163
-
-
59649112895
-
Insulin resistance in pulmonary arterial hypertension
-
Zamanian RT, Hansmann G, Snook S, Lilienfeld D, Rappaport KM, Reaven GM, Rabinovitch M, Doyle RL. Insulin resistance in pulmonary arterial hypertension. Eur Respir J 33: 318-324, 2009.
-
(2009)
Eur Respir J
, vol.33
, pp. 318-324
-
-
Zamanian, R.T.1
Hansmann, G.2
Snook, S.3
Lilienfeld, D.4
Rappaport, K.M.5
Reaven, G.M.6
Rabinovitch, M.7
Doyle, R.L.8
-
164
-
-
0030990991
-
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
-
Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 94: 3789-3794, 1997.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3789-3794
-
-
Zambrowicz, B.P.1
Imamoto, A.2
Fiering, S.3
Herzenberg, L.A.4
Kerr, W.G.5
Soriano, P.6
-
165
-
-
14844360656
-
Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: Efficacy of combined cell and eNOS gene therapy in established disease
-
Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: Efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 96: 442-450, 2005.
-
(2005)
Circ Res
, vol.96
, pp. 442-450
-
-
Zhao, Y.D.1
Courtman, D.W.2
Deng, Y.3
Kugathasan, L.4
Zhang, Q.5
Stewart, D.J.6
-
166
-
-
33746838551
-
Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer
-
Zhao YD, Courtman DW, Ng DS, Robb MJ, Deng YP, Trogadis J, Han RN, Stewart DJ. Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer. Am J Respir Cell Mol Biol 35: 182-189, 2006.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 182-189
-
-
Zhao, Y.D.1
Courtman, D.W.2
Ng, D.S.3
Robb, M.J.4
Deng, Y.P.5
Trogadis, J.6
Han, R.N.7
Stewart, D.J.8
-
167
-
-
68849084669
-
Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration
-
Zhao YY, Zhao YD, Mirza MK, Huang JH, Potula HH, Vogel SM, Brovkovych V, Yuan JX, Wharton J, Malik AB. Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration. J Clin Invest 119(7): 2009-2018, 2009.
-
(2009)
J Clin Invest
, vol.119
, Issue.7
, pp. 2009-2018
-
-
Zhao, Y.Y.1
Zhao, Y.D.2
Mirza, M.K.3
Huang, J.H.4
Potula, H.H.5
Vogel, S.M.6
Brovkovych, V.7
Yuan, J.X.8
Wharton, J.9
Malik, A.B.10
-
168
-
-
0026647803
-
Pulmonary vascular impedance and wave reflections in the hypoxic calf
-
Zuckerman BD, Orton EC, Latham LP, Barbiere CC, Stenmark KR, Reeves JT. Pulmonary vascular impedance and wave reflections in the hypoxic calf. J Appl Physiol 72: 2118-2127, 1992.
-
(1992)
J Appl Physiol
, vol.72
, pp. 2118-2127
-
-
Zuckerman, B.D.1
Orton, E.C.2
Latham, L.P.3
Barbiere, C.C.4
Stenmark, K.R.5
Reeves, J.T.6
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