-
1
-
-
0033071540
-
Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity
-
Funahashi T, Nakamura T, Shimomura I, et al. Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity. Intern Med 1999; 38:202-206.
-
(1999)
Intern Med
, vol.38
, pp. 202-206
-
-
Funahashi, T.1
Nakamura, T.2
Shimomura, I.3
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
-
3
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993; 259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
4
-
-
15844381594
-
Enhanced expression of PAM in visceral fat: Possible contributor to vascular disease in obesity
-
Shimomura I, Funahashi T, Takahashi M, et al. Enhanced expression of PAM in visceral fat: possible contributor to vascular disease in obesity. Nat Med 1996; 2:800-803.
-
(1996)
Nat Med
, vol.2
, pp. 800-803
-
-
Shimomura, I.1
Funahashi, T.2
Takahashi, M.3
-
5
-
-
0029980285
-
CDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant Gene transcript 1)
-
Maeda K, Okubo K, Shimomura I, et al. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996; 221:286-289.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 286-289
-
-
Maeda, K.1
Okubo, K.2
Shimomura, I.3
-
6
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257:79-83.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
-
7
-
-
0028787490
-
A novel serum protein similar to C1q, produced exclusively in adipocytes
-
Scherer PE Williams S, Fogliano M, et al. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270:26746-26749.
-
(1995)
J Biol Chem
, vol.270
, pp. 26746-26749
-
-
Scherer, P.E.1
Williams, S.2
Fogliano, M.3
-
8
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271:10697-10703.
-
(1996)
J Biol Chem
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
9
-
-
0029836585
-
Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
-
Nakano Y, Tobe T, Choi-Miura NH, et al. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 1996; 20:803-812.
-
(1996)
J Biochem (Tokyo)
, vol.20
, pp. 803-812
-
-
Nakano, Y.1
Tobe, T.2
Choi-Miura, N.H.3
-
10
-
-
0032510463
-
The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
-
Shapiro L, Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 1998; 8:335-338.
-
(1998)
Curr Biol
, vol.8
, pp. 335-338
-
-
Shapiro, L.1
Scherer, P.E.2
-
11
-
-
0035039227
-
Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
-
Hotta K, Funahashi T, Bodkin NL, et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001; 50:1126-1133.
-
(2001)
Diabetes
, vol.50
, pp. 1126-1133
-
-
Hotta, K.1
Funahashi, T.2
Bodkin, N.L.3
-
12
-
-
0037984387
-
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin: Implications for metabolic regulation and bioactivity
-
Pajvani UB, Du X, Combs TP, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin: implications for metabolic regulation and bioactivity. J Biol Chem 2003; 278:9073-9085.
-
(2003)
J Biol Chem
, vol.278
, pp. 9073-9085
-
-
Pajvani, U.B.1
Du, X.2
Combs, T.P.3
-
13
-
-
0038054254
-
Disturbed secretion of mutant adiponectin associated with the metabolic syndrome
-
Kishida K, Nagaretani H, Kondo H, et al. Disturbed secretion of mutant adiponectin associated with the metabolic syndrome. Biochem Biophys Res Commun 2003; 306:286-292.
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 286-292
-
-
Kishida, K.1
Nagaretani, H.2
Kondo, H.3
-
14
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, Tsao TS, Javorschi S, et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A 2001; 98:2005-2010.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
-
15
-
-
0038293399
-
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: Evidence for independent roles of age and sex
-
Cnop M, Havel PJ, Utzschneider KM, et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 2003; 46:459-469.
-
(2003)
Diabetologia
, vol.46
, pp. 459-469
-
-
Cnop, M.1
Havel, P.J.2
Utzschneider, K.M.3
-
16
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86:1930-1935.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
-
17
-
-
0034096988
-
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
-
Hotta K, Funahashi T, Arita Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000; 20:1595-1599.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1595-1599
-
-
Hotta, K.1
Funahashi, T.2
Arita, Y.3
-
18
-
-
0034891684
-
Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
-
Yang WS, Lee WJ, Funahashi T, et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Metab 2001; 86:3815-3819.
-
(2001)
J Clin Metab
, vol.86
, pp. 3815-3819
-
-
Yang, W.S.1
Lee, W.J.2
Funahashi, T.3
-
19
-
-
0037540732
-
Resistin and adiponectin expression in visceral fat of obese rats: Effect of weight loss
-
Milan G, Granzotto M, Scarda A, et al. Resistin and adiponectin expression in visceral fat of obese rats: effect of weight loss. Obes Res 2002; 10:1095-1103.
-
(2002)
Obes Res
, vol.10
, pp. 1095-1103
-
-
Milan, G.1
Granzotto, M.2
Scarda, A.3
-
20
-
-
0037031088
-
Adiponectin and development of type 2 diabetes in the Pima Indian population
-
Lindsay RS, Funahashi T, Hanson RL, et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 2002; 360:57-58. This was an excellent clinical study that clearly showed the relationship between adiponectin and development of type 2 diabetes.
-
(2002)
Lancet
, vol.360
, pp. 57-58
-
-
Lindsay, R.S.1
Funahashi, T.2
Hanson, R.L.3
-
21
-
-
0037452139
-
Adiponectin and protection against type 2 diabetes mellitus
-
Spranger J, Kroke A, Mohlig M, et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 2003; 361:226-228.
-
(2003)
Lancet
, vol.361
, pp. 226-228
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
-
22
-
-
0033613545
-
Novel modulator for endothelial adhesion molecules; Adipocyte-derived plasma protein, adiponectin
-
Ouchi N, Kihara S, Arita Y, et al. Novel modulator for endothelial adhesion molecules; Adipocyte-derived plasma protein, adiponectin. Circulation 1999; 100:2473-2476.
-
(1999)
Circulation
, vol.100
, pp. 2473-2476
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
23
-
-
0037231459
-
Association of hypoadiponectinemia with coronary artery disease in men
-
Kumada M, Kihara S, Sumitsuji S, et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003; 23:85-89.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 85-89
-
-
Kumada, M.1
Kihara, S.2
Sumitsuji, S.3
-
24
-
-
0036139677
-
Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease
-
Zoccali C, Mallamaci F, Tripepi G, et al. Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol 2002; 13:134-141.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 134-141
-
-
Zoccali, C.1
Mallamaci, F.2
Tripepi, G.3
-
25
-
-
17744420209
-
Adiponectin is markedly increased in patients with nephrotic syndrome and is related to metabolic risk factors
-
Zoccali C, Mallamaci F, Panuccio V, et al. Adiponectin is markedly increased in patients with nephrotic syndrome and is related to metabolic risk factors. Kidney Int (Suppl) 2003; 84:398-3102.
-
(2003)
Kidney Int (Suppl)
, vol.84
, pp. 398-3102
-
-
Zoccali, C.1
Mallamaci, F.2
Panuccio, V.3
-
26
-
-
0038824160
-
The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction
-
Kojima S, Funahashi T, Sakamoto T, et al. The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction. (Letter) Heart 2003; 89:667.
-
(2003)
(Letter) Heart
, vol.89
, pp. 667
-
-
Kojima, S.1
Funahashi, T.2
Sakamoto, T.3
-
27
-
-
0035955760
-
Novel clinical markers of vascular wall inflammation
-
Blake GJ, Ridker PM. Novel clinical markers of vascular wall inflammation. Circ Res 2001; 89:763-771.
-
(2001)
Circ Res
, vol.89
, pp. 763-771
-
-
Blake, G.J.1
Ridker, P.M.2
-
28
-
-
0037022237
-
Weight loss reduces C-reactive protein levels in obese postmenopausal women
-
Tchernof A, Nolan A, Sites CK, et al. Weight loss reduces C-reactive protein levels in obese postmenopausal women. Circulation 2002; 105:564-569.
-
(2002)
Circulation
, vol.105
, pp. 564-569
-
-
Tchernof, A.1
Nolan, A.2
Sites, C.K.3
-
29
-
-
0037432152
-
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue
-
Ouchi N, Kihara S, Funahashi T, et al. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 2003; 107:671-674. This is an interesting report of C-reactive protein expression in human adipose tissue and the inverse correlation between C-reactive protein and adiponectin in both plasma and adipose tissue.
-
(2003)
Circulation
, vol.107
, pp. 671-674
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
-
30
-
-
0037380664
-
Association between adiponectin and mediators of inflammation in obese women
-
Engeli S, Feldpausch M, Gorzelniak K, et al. Association between adiponectin and mediators of inflammation in obese women. Diabetes 2003; 52:942-947.
-
(2003)
Diabetes
, vol.52
, pp. 942-947
-
-
Engeli, S.1
Feldpausch, M.2
Gorzelniak, K.3
-
31
-
-
10744231067
-
Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
-
Krakoff J, Funahashi T, Stehouwer CD, et al. Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. Diabetes Care 2003; 26:1745-1751.
-
(2003)
Diabetes Care
, vol.26
, pp. 1745-1751
-
-
Krakoff, J.1
Funahashi, T.2
Stehouwer, C.D.3
-
32
-
-
0037530638
-
Decreased plasma adiponectin concentrations in women with low-grade C-reactive protein elevation
-
Matsubara M, Namioka K, Katayose S. Decreased plasma adiponectin concentrations in women with low-grade C-reactive protein elevation. Eur J Endocrinol 2003; 148:657-662.
-
(2003)
Eur J Endocrinol
, vol.148
, pp. 657-662
-
-
Matsubara, M.1
Namioka, K.2
Katayose, S.3
-
33
-
-
0037840403
-
Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
-
Esposito K, Pontillo A, Di Palo C, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA 2003; 289:1799-1804.
-
(2003)
JAMA
, vol.289
, pp. 1799-1804
-
-
Esposito, K.1
Pontillo, A.2
Di Palo, C.3
-
34
-
-
0037459090
-
Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes
-
Fasshauer M, Kralisch S, Klier M, et al. Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2003; 301:1045-1050.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 1045-1050
-
-
Fasshauer, M.1
Kralisch, S.2
Klier, M.3
-
35
-
-
0034284038
-
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
-
Yokota T, Oritani K, Takahashi I, et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000; 96:1723-1732.
-
(2000)
Blood
, vol.96
, pp. 1723-1732
-
-
Yokota, T.1
Oritani, K.2
Takahashi, I.3
-
36
-
-
0036063777
-
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
-
Maeda N, Shimomura I, Kishida K, et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 2002; 8:731-737. This outstanding study described the association of adiponectin deficiency with insulin resistance in vivo.
-
(2002)
Nat Med
, vol.8
, pp. 731-737
-
-
Maeda, N.1
Shimomura, I.2
Kishida, K.3
-
37
-
-
0037020170
-
Role of adiponectin in preventing vascular stenosis: The missing link of adipo-vascular axis
-
Matsuda M, Shimomura I, Sata M, et al. Role of adiponectin in preventing vascular stenosis: the missing link of adipo-vascular axis. J Biol Chem 2002; 277:37487-37491. This report demonstrates for the first time that adiponectin deficiency directly causes excess vascular remodeling response to injury.
-
(2002)
J Biol Chem
, vol.277
, pp. 37487-37491
-
-
Matsuda, M.1
Shimomura, I.2
Sata, M.3
-
38
-
-
10744223954
-
Association of hypoadiponectinemia with impaired vasoreactivity
-
Jul 14 [Epub ahead of print]
-
Ouchi N, Ohishi M, Kihara S, et al. Association of hypoadiponectinemia with impaired vasoreactivity. Hypertension 2003 Jul 14 [Epub ahead of print].
-
(2003)
Hypertension
-
-
Ouchi, N.1
Ohishi, M.2
Kihara, S.3
-
39
-
-
0034881391
-
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
-
Berg AH, Combs TP, Du X, et al. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001; 7:947-953.
-
(2001)
Nat Med
, vol.7
, pp. 947-953
-
-
Berg, A.H.1
Combs, T.P.2
Du, X.3
-
40
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8:1288-1295.
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
-
41
-
-
0037059013
-
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
-
Tomas E, Tsao TS, Saha AK, et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002; 99:16309-16313.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16309-16313
-
-
Tomas, E.1
Tsao, T.S.2
Saha, A.K.3
-
42
-
-
0037135523
-
Disruption of adiponectin causes insulin resistance and neointimal formation
-
Kubota N, Terauchi Y, Yamauchi T, et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002; 277:25863-25866.
-
(2002)
J Biol Chem
, vol.277
, pp. 25863-25866
-
-
Kubota, N.1
Terauchi, Y.2
Yamauchi, T.3
-
43
-
-
0037144394
-
Increased beta-oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin
-
Ma K, Cabrero A, Saha PK, et al. Increased beta-oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin. J Biol Chem 2002; 277:34658-34661.
-
(2002)
J Biol Chem
, vol.277
, pp. 34658-34661
-
-
Ma, K.1
Cabrero, A.2
Saha, P.K.3
-
44
-
-
0034641647
-
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
-
Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000; 102:1296-1301.
-
(2000)
Circulation
, vol.102
, pp. 1296-1301
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
45
-
-
0035957040
-
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class a scavenger receptor expression in human monocyte-derived macrophages
-
Ouchi N, Kihara S, Arita Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001; 103:1057-1063.
-
(2001)
Circulation
, vol.103
, pp. 1057-1063
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
46
-
-
0037129861
-
Adipocyte-derived plasma protein, adiponectin, acts as a platelet-derived growth factor-BB binding protein, and regulates growth factor-induced common post-receptor signal in vascular smooth muscle cell
-
Arita Y, Kihara S, Ouchi N, et al. Adipocyte-derived plasma protein, adiponectin, acts as a platelet-derived growth factor-BB binding protein, and regulates growth factor-induced common post-receptor signal in vascular smooth muscle cell. Circulation 2002; 105:2893-2898.
-
(2002)
Circulation
, vol.105
, pp. 2893-2898
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
-
47
-
-
0034014647
-
An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular wall
-
Okamoto Y, Arita Y, Nishida M, et al. An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular wall. Horm Metab Res 2000; 32:47-50.
-
(2000)
Horm Metab Res
, vol.32
, pp. 47-50
-
-
Okamoto, Y.1
Arita, Y.2
Nishida, M.3
-
48
-
-
0037180472
-
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
-
Okamoto Y, Kihara S, Ouchi N, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 2002; 106:2767-2770.
-
(2002)
Circulation
, vol.106
, pp. 2767-2770
-
-
Okamoto, Y.1
Kihara, S.2
Ouchi, N.3
-
49
-
-
0037462684
-
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
-
Yamauchi T, Kamon J, Waki H, et al. Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem 2003; 278:2461-2468.
-
(2003)
J Biol Chem
, vol.278
, pp. 2461-2468
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
|