Serotonin modulates the cytokine network in the lung: Involvement of prostaglandin E2

Clinical and Experimental Immunology

Volumn 150, Issue 2, 2007, Pages 340-348

  Menard G ^a   Turmel, V ^a   Bissonnette, E Y ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Alveolar macrophages; Human; IL 10; IL 12; NO; PGE2; Serotonin; TNF

Indexed keywords

ANTIBODY; CYTOKINE; INDOMETACIN; INTERLEUKIN 10; INTERLEUKIN 12; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 2 ANTAGONIST; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; ASTHMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; TH1 CELL; TH2 CELL;

ANIMALS; ASTHMA; CELL LINE; CYTOKINES; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; INTERLEUKIN-10; MACROPHAGES, ALVEOLAR; NITRIC OXIDE; RATS; RECEPTORS, SEROTONIN, 5-HT1; RECEPTORS, SEROTONIN, 5-HT2; SEROTONIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 35348969860     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03492.x     Document Type: Article

References (51)

1. Kraal G, Broug E, Thepen T, Van Iwaarden JF, Persoons JHA. The role of alveolar macrophages in pulmonary immune function. In : Lipscomb MF, Russell SW, eds. Lung macrophages and dendritic cells in health and disease. New York : Marcel Dekker Inc., 1997 203 20.
2. Burastero SE, Magnani Z, Confetti C et al. Increased expression of the CD80 accessory molecule by alveolar macrophages in asthmatic subjects and its functional involvement in allergen presentation to autologous TH2 lymphocytes. J Allergy Clin Immunol 1999 103 : 1136 42.
3. Alexis NE, Soukup J, Nierkens S, Becker S. Association between airway hyperreactivity and bronchial macrophage dysfunction in individuals with mild asthma. Am J Physiol Lung Cell Mol Physiol 2001 280 : L369 75.
4. Rankin JA. The contribution of alveolar macrophages to hyperreactive airway disease. J Allergy Clin Immunol 1989 83 : 722 9.
5. Cluzel M, Damon M, Chanez P et al. Enhanced alveolar cell luminol-dependent chemiluminescence in asthma. J Allergy Clin Immunol 1987 80 : 195 201.
6. Vignola AM, Chanez P, Campbell AM et al. Airway inflammation in mild intermittent and in persistent asthma. Am J Respir Crit Care Med 1998 157 : 403 9.
7. Tang C, Rolland JM, Li X, Ward C, Bish R, Walters EH. Alveolar macrophages from atopic asthmatics, but not atopic nonasthmatics, enhance interleukin-5 production by CD4+ T cells. Am J Respir Crit Care Med 1998 157 : 1120 6.
8. Kushnir-Sukhov NM, Brown JM, Wu Y, Kirshenbaum A, Metcalfe DD. Human mast cells are capable of serotonin synthesis and release. J Allergy Clin Immunol 2007 119 : 498 9.
9. Matsuda H, Ushio H, Geba GP, Askenase PW. Human platelets can initiate T cell-dependent contact sensitivity through local serotonin release mediated by IgE antibodies. J Immunol 1997 158 : 2891 7.
10. Deakin JF. The role of serotonin in panic, anxiety and depression. Int Clin Psychopharmacol 1998 13 (Suppl. 4 S1 5.
11. Young MR, Kut JL, Coogan MP, Wright MA, Young ME, Matthews J. Stimulation of splenic T-lymphocyte function by endogenous serotonin and by low-dose exogenous serotonin. Immunology 1993 80 : 395 400.
12. Slauson DO, Walker C, Kristensen F, Wang Y, de Weck AL. Mechanisms of serotonin-induced lymphocyte proliferation inhibition. Cell Immunol 1984 84 : 240 52.
13. Sternberg EM, Wedner HJ, Leung MK, Parker CW. Effect of serotonin (5-HT) and other monoamines on murine macrophages: modulation of interferon-gamma induced phagocytosis. J Immunol 1987 138 : 4360 5.
14. Arzt E, Costas M, Finkielman S, Nahmod VE. Serotonin inhibition of tumor necrosis factor-alpha synthesis by human monocytes. Life Sci 1991 48 : 2557 62.
15. Kubera M, Kenis G, Bosmans E, Scharpe S, Maes M. Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-gamma and interleukin-10. Neuropsychopharmacology 2000 23 : 89 98.
16. Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM. Differential effect of serotonin on cytokine production in lipopolysaccharide- stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors. Int Immunol 2003 15 : 233 40.
17. Lechin F, van der Dijs B, Orozco B et al. Neuropharmacologic treatment of bronchial asthma with the antidepressant tianeptine: a double-blind, crossover placebo-controlled study. Clin Pharmacol Ther 1998 64 : 223 32.
18. Pretorius E. Corticosteroids, depression and the role of serotonin. Rev Neurosci 2004 15 : 109 16.
19. Janson C, Bjornsson E, Hetta J, Boman G. Anxiety and depression in relation to respiratory symptoms and asthma. Am J Respir Crit Care Med 1994 149 : 930 4.
20. Lechin F, van der Dijs B, Orozco B, Lechin M, Lechin AE. Increased levels of free serotonin in plasma of symptomatic asthmatic patients. Ann Allergy Asthma Immunol 1996 77 : 245 53.
21. Sirois J, Menard G, Moses AS, Bissonnette EY. Importance of histamine in the cytokine network in the lung through H2 and H3 receptors: stimulation of IL-10 production. J Immunol 2000 164 : 2964 70.
22. Scales WE, Chensue SW, Otterness I, Kunkel SL. Regulation of monokine gene expression. prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity. J Leukoc Biol 1989 45 : 416 21.
23. Aune TM, Golden HW, McGrath KM. Inhibitors of serotonin synthesis and antagonists of serotonin 1A receptors inhibit T lymphocyte function in vitro and cell-mediated immunity in vivo. J Immunol 1994 153 : 489 98.
24. Idzko M, Panther E, Stratz C et al. The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine release. J Immunol 2004 172 : 6011 19.
25. Kubera M, Maes M, Kenis G, Kim YK, Lason W. Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6. Psychiatry Res 2005 134 : 251 8.
26. Durk T, Panther E, Muller T et al. 5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes. Int Immunol 2005 17 : 599 606.
27. Stefulj J, Jernej B, Cicin-Sain L, Rinner I, Schauenstein K. mRNA expression of serotonin receptors in cells of the immune tissues of the rat. Brain Behav Immun 2000 14 : 219 24.
28. Profita M, Sala A, Bonanno A et al. Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia. J Allergy Clin Immunol 2003 112 : 709 16.
29. Stroebel M, Goppelt-Struebe M. Signal transduction pathways responsible for serotonin-mediated prostaglandin G/H synthase expression in rat mesangial cells. J Biol Chem 1994 269 : 22952 7.
30. Shibata Y, Henriksen RA, Honda I, Nakamura RM, Myrvik QN. Splenic PGE2-releasing macrophages regulate Th1 and Th2 immune responses in mice treated with heat-killed BCG. J Leukoc Biol 2005 78 : 1281 90.
31. Betz M, Fox BS. Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol 1991 146 : 108 13.
32. Snijdewint FG, Kalinski P, Wierenga EA, Bos JD, Kapsenberg ML. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993 150 : 5321 9.
33. Cheon H, Rho YH, Choi SJ et al. Prostaglandin E2 augments IL-10 signaling and function. J Immunol 2006 177 : 1092 100.
34. Jin M, Opalek JM, Marsh CB, Wu HM. Proteome comparison of alveolar macrophages with monocytes reveals distinct protein characteristics. Am J Respir Cell Mol Biol 2004 31 : 322 9.
35. Strassmann G, Patil-Koota V, Finkelman F, Fong M, Kambayashi T. Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J Exp Med 1994 180 : 2365 70.
36. Vivancos M, Moreno JJ. Role of Ca(2+)-independent phospholipase A(2) and cyclooxygenase/lipoxygenase pathways in the nitric oxide production by murine macrophages stimulated by lipopolysaccharides. Nitric Oxide 2002 6 : 255 62.
37. Hrabak A, Vercruysse V, Kahan IL, Vray B. Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production. Life Sci 2001 68 : 1923 30.
38. Pacifici R, Zuccaro P, Hernandez Lopez C et al. Acute effects of 3,4-methylenedioxymethamphetamine alone and in combination with ethanol on the immune system in humans. J Pharmacol Exp Ther 2001 296 : 207 15.
39. Connor TJ, Connelly DB, Kelly JP. Methylenedioxymethamphetamine (MDMA; 'Ecstasy') suppresses antigen specific IgG2a and IFN-gamma production. Immunol Lett 2001 78 : 67 73.
40. Connor TJ. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system. Immunology 2004 111 : 357 67.
41. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996 17 : 138 46.
42. Hawrylowicz CM. Regulatory T cells and IL-10 in allergic inflammation. J Exp Med 2005 202 : 1459 63.
43. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989 170 : 2081 95.
44. Borish L, Aarons A, Rumbyrt J, Cvietusa P, Negri J, Wenzel S. Interleukin-10 regulation in normal subjects and patients with asthma. J Allergy Clin Immunol 1996 97 : 1288 96.
45. Lin TJ, Befus AD. Differential regulation of mast cell function by IL-10 and stem cell factor. J Immunol 1997 159 : 4015 23.
46. Buelens C, Verhasselt V, De Groote D, Thielemans K, Goldman M, Willems F. Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage- colony-stimulating factor. Eur J Immunol 1997 27 : 756 62.
47. Grissell TV, Powell H, Shafren DR et al. Interleukin-10 gene expression in acute virus-induced asthma. Am J Respir Crit Care Med 2005 172 : 433 9.
48. Matsumoto K, Inoue H, Tsuda M et al. Different roles of interleukin-10 in onset and resolution of asthmatic responses in allergen-challenged mice. Respirology 2005 10 : 18 26.
49. Long JA, Fogel-Petrovic M, Knight DA, Thompson PJ, Upham JW. Higher prostaglandin E2 production by dendritic cells from subjects with asthma compared with normal subjects. Am J Respir Crit Care Med 2004 170 : 485 91.
50. Frazer A. Serotonergic and noradrenergic reuptake inhibitors: prediction of clinical effects from in vitro potencies. J Clin Psychiatry 2001 62 (Suppl. 12 16 23.
51. Wagstaff AJ, Ormrod D, Spencer CM. Tianeptine: a review of its use in depressive disorders. CNS Drugs 2001 15 : 231 59.