Contribution of the 5-HT1B receptor to hypoxia-induced pulmonary hypertension: Converging evidence using 5-HT1B-receptor knockout mice and the 5-HT1B/1D-receptor antagonist GR127935

Circulation Research

Volumn 89, Issue 12, 2001, Pages 1231-1239

  Keegan, Alan ^a   Morecroft, Ian ^a   Smillie, Diane ^b   Hicks, Martin N ^b   MacLean, Margaret R ^a,b  

^a Institute of Biomedical and Life Sciences   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

5 HT1B receptor antagonist; 5 HT1B receptor knockout mice; Pulmonary hypertension

Indexed keywords

5 CARBAMOYLTRYPTAMINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; SEROTONIN 1 AGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HYPOXIA; KNOCKOUT MOUSE; LUNG CIRCULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; RECEPTOR BINDING; REGULATORY MECHANISM; THICKNESS; WILD TYPE;

EID: 0035824915     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh2401.100426     Document Type: Article

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