2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats

Vascular Pharmacology

Volumn 51, Issue 2-3, 2009, Pages 190-197

  Tofovic, Stevan P ^a   Zhang, Xinchen ^a   Jackson, Edwin K ^a   Zhu, Hong ^a   Petrusevska, Gordana ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Estradiol; Estradiol metabolites; Pulmonary fibrosis; Pulmonary hypertension

Indexed keywords

2 METHOXYESTRADIOL; BLEOMYCIN; ESTRADIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; ESTROGEN DEFICIENCY; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYPERTROPHY; LUNG ARTERY; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG INJURY; MORTALITY; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; VASCULAR SMOOTH MUSCLE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMITOTIC AGENTS; ARTERIOLES; BLEOMYCIN; CELL LINE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGENS; FEMALE; FIBROBLASTS; HUMANS; HYPERTENSION, PULMONARY; LUNG; MYOCYTES, SMOOTH MUSCLE; ORGAN SIZE; OVARIECTOMY; PULMONARY ARTERY; PULMONARY FIBROSIS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 68149181704     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2009.06.002     Document Type: Article

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