Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 1, 2010, Pages

  Casey, David B ^a   Badejo, Adeleke M ^a   Dhaliwal, Jasdeep S ^a   Sikora, James L ^a   Fokin, Alex ^a   Golwala, Neel H ^a   Greco, Anthony J ^a   Murthy, Subramanyam N ^a   Nossaman, Bobby D ^a,b   Hyman, Albert L ^a   Kadowitz, Philip J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OCHSNER CLINIC FOUNDATION   (United States)

Author keywords

BAY 41 8543; Hypoxic pulmonary vasoconstriction; Nitric oxide release; Pulmonary vasodilation; Systemic vasodilation

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL] 5 MORPHOLINO 4,6 PYRIMIDINEDIAMINE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ANGIOTENSIN II; N(G) NITROARGININE METHYL ESTER; RHO KINASE INHIBITOR; SEROTONIN; SODIUM NITRITE;

ARTERIAL PRESSURE; ARTICLE; DRUG EFFECT; ENDOTHELIUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASOCONSTRICTION; VASODILATATION;

AMIDES; ANIMALS; ANOXIA; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME ACTIVATORS; ENZYME INHIBITORS; GUANYLATE CYCLASE; HEMODYNAMICS; HYPERTENSION, PULMONARY; INJECTIONS, INTRAVENOUS; MALE; MONOCROTALINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE INHIBITORS; PULMONARY CIRCULATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RHO-ASSOCIATED KINASES; TIME FACTORS; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 77953786515     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00181.2009     Document Type: Article

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