Liver inflammation during monocrotaline hepatotoxicity

Toxicology

Volumn 190, Issue 3, 2003, Pages 155-169

  Copple, Bryan L ^a   Ganey, Patricia E ^a   Roth, Robert A ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Chemokines; Inflammation; Kupffer cell; Liver; Monocrotaline; Neutrophil

Indexed keywords

CHEMOKINE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; GADOLINIUM CHLORIDE; GRANULOCYTE ANTIBODY; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCROTALINE; MONOCYTE CHEMOTACTIC PROTEIN 1; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; CELL FUNCTION; CHRONOLOGY; CONTROLLED STUDY; DRUG EFFECT; HEPATITIS; INHIBITION KINETICS; KUPFFER CELL; LIVER CELL; LIVER CELL DAMAGE; LIVER PARENCHYMA; LIVER TOXICITY; MALE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; TISSUE INJURY; UPREGULATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0042634149     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(03)00164-1     Document Type: Article

References (49)

1. Adachi Y., Bradford B.U., Gao W., Bojes H.K., Thurman R.G. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology. 20:1994;453-460.
2. Allen J.R., Carstens L.A., Katagiri G.J. Hepatic veins of monkeys with veno-occlusive disease. Sequential ultrastructural changes. Arch. Pathol. 87:1969;279-289.
3. Bajt M.L., Farhood A., Jaeschke H. Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature. Am. J. Physiol. Gastrointest. Liver Physiol. 281:2001;G1188-G1195.
4. Bautista A.P. Chronic alcohol intoxication primes Kupffer cells and endothelial cells for enhanced CC-chemokine production and concomitantly suppresses phagocytosis and chemotaxis. Front Biosci. 7:2002;a117-a125.
5. Brooks S.E., Miller C.G., McKenzie K., Audretsch J.J., Bras G. Acute veno-occlusive disease of the liver. Fine structure in Jamaican children. Arch. Pathol. 89:1970;507-520.
6. Brown A.P., Harkema J.R., Schultze A.E., Roth R.A., Ganey P.E. Gadolinium chloride pretreatment protects against hepatic injury but predisposes the lungs to alveolitis after lipopolysaccharide administration. Shock. 7:1997;186-192.
7. Calkins C.M., Bensard D.D., Shames B.D., Pulido E.J., Abraham E., Fernandez N., Meng X., Dinarello C.A., McIntyre R.C.J. IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia. J. Endotoxin Res. 8:2002;59-67.
8. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
9. Colman R.W., Marder V.J., Salzman E.W., Hirsh J. Overview of hemostasis. Colman R.W., Hirsh J., Marder V.J., Salzman E.W. Hemostasis and Thrombosis. 1994;3 Lippincott, Philadelphia.
10. Copple B.L., Perez Rivera A.A., Ganey P.E., Roth R.A. Neutrophils and monocrotaline-induced liver injury. Toxicologist. 60:2001;351-351. Abstract.
11. Copple B.L., Banes A., Ganey P.E., Roth R.A. Endothelial cell injury and fibrin deposition in rat liver after monocrotaline exposure. Toxicol. Sci. 65:2002;309-318.
12. Copple B.L., Woolley B., Banes A., Ganey P.E., Roth R.A. Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat. Toxicol. Appl. Pharmacol. 180:2002;186-196.
13. Dahm L.J., Schultze A.E., Roth R.A. An antibody to neutrophils attenuates alpha-naphthylisothiocyanate- induced liver injury. J. Pharmacol. Exp. Ther. 256:1991;412-420.
14. Dambach D.M., Watson L.M., Gray K.R., Durham S.K., Laskin D.L. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology. 35:2002;1093-1103.
15. DeLeve L.D., McCuskey R.S., Wang X., Hu L., McCuskey M.K., Epstein R.B., Kanel G.C. Characterization of a reproducible rat model of hepatic veno-occlusive disease. Hepatology. 29:1999;1779-1791.
16. DeLeve L.D., Shulman H.M., McDonald G.B. Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin. Liver Dis. 22:2002;27-42.
17. Ganey P.E., Schultze A.E. Depletion of neutrophils and modulation of Kupffer cell function in allyl alcohol-induced hepatotoxicity. Toxicology. 99:1995;99-106.
18. Hardonk M.J., Dijkhuis F.W., Hulstaert C.E., Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J. Leukoc. Biol. 52:1992;296-302.
19. Harstad E.B., Klaassen C.D. Analysis of strain difference in sensitivity to cadmium-induced hepatotoxicity in Fischer 344 and Sprague-Dawley rats. Toxicol. Sci. 67:2002;329-340.
20. Hewett J.A., Roth R.A. The coagulation system, but not circulating fibrinogen, contributes to liver injury in rats exposed to lipopolysaccharide from gram-negative bacteria. J. Pharmacol. Exp. Ther. 272:1995;53-62.
21. Hewett J.A., Schultze A.E., VanCise S., Roth R.A. Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab. Invest. 66:1992;347-361.
22. Hewett J.A., Jean P.A., Kunkel S.L., Roth R.A. Relationship between tumor necrosis factor-alpha and neutrophils in endotoxin-induced liver injury. Am. J. Physiol. 265:1993;G1011-G1015.
23. Higure A., Okamoto K., Hirata K., Todoroki H., Nagafuchi Y., Takeda S., Katoh H., Itoh H., Ohsato K., Nakamura S. Macrophages and neutrophils infiltrating into the liver are responsible for tissue factor expression in a rabbit model of acute obstructive cholangitis. Thromb. Haemost. 75:1996;791-795.
24. Hisama N., Yamaguchi Y., Okajima K., Uchiba M., Murakami K., Mori K., Yamada S., Ogawa M. Anticoagulant pretreatment attenuates production of cytokine-induced neutrophil chemoattractant following ischemia-reperfusion of rat liver. Dig. Dis. Sci. 41:1996;1481-1486.
25. Huxtable R.J. Human health implications of pyrrolizidine alkaloids and herbs containing them. Cheeke P.R. Toxicants of Plant Origin. 1989;41-86 CRC Press, Boca Raton.
26. Jaeschke H. Cellular adhesion molecules: regulation and functional significance in the pathogenesis of liver diseases. Am. J. Physiol. 273:1997;G602-G611.
27. Jaeschke H., Farhood A., Smith C.W. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB J. 4:1990;3355-3359.
28. Jaeschke H., Smith C.W., Clemens M.G., Ganey P.E., Roth R.A. Mechanisms of inflammatory liver injury: adhesion molecules and cytotoxicity of neutrophils. Toxicol. Appl. Pharmacol. 139:1996;213-226.
29. Laskin D.L., Gardner C.R., Price V.F., Jollow D.J. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology. 21:1995;1045-1050.
30. Lawson J.A., Farhood A., Hopper R.D., Bajt M.L., Jaeschke H. The hepatic inflammatory response after acetaminophen overdose: role of neutrophils. Toxicol. Sci. 54:2000;509-516.
31. Maher J.J. Rat hepatocytes and Kupffer cells interact to produce interleukin-8 (CINC) in the setting of ethanol. Am. J. Physiol. 269:1995;G518-G523.
32. Maher J.J. Interactions between hepatic stellate cells and the immune system. Semin. Liver Dis. 21:2001;417-426.
33. Maher J.J., Scott M.K., Saito J.M., Burton M.C. Adenovirus-mediated expression of cytokine-induced neutrophil chemoattractant in rat liver induces a neutrophilic hepatitis. Hepatology. 25:1997;624-630.
34. McFadden G., Kelvin D. New strategies for chemokine inhibition and modulation: you take the high road and I'll take the low road. Biochem. Pharmacol. 54:1997;1271-1280.
35. Mosher B., Dean R., Harkema J., Remick D., Palma J., Crockett E. Inhibition of Kupffer cells reduced CXC chemokine production and liver injury. J. Surg. Res. 99:2001;201-210.
36. Noel P., Nelson S., Bokulic R., Bagby G., Lippton H., Lipscomb G., Summer W. Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality. Life Sci. 47:1990;1023-1029.
37. Ohkubo K., Masumoto T., Horiike N., Onji M. Induction of CINC (interleukin-8) production in rat liver by non-parenchymal cells. J. Gastroenterol. Hepatol. 13:1998;696-702.
38. Pearson J.M., Schultze A.E., Jean P.A., Roth R.A. Platelet participation in liver injury from gram-negative bacterial lipopolysaccharide in the rat. Shock. 4:1995;178-186.
39. Pearson J.M., Brown A.P., Schultze A.E., Ganey P.E., Roth R.A. Gadolinium chloride treatment attenuates hepatic platelet accumulation after lipopolysaccharide administration. Shock. 5:1996;408-415.
40. Pennington H.L., Wilce P.A., Worrall S. Chemokine and cell adhesion molecule mRNA expression and neutrophil infiltration in lipopolysaccharide-induced hepatitis in ethanol-fed rats. Alcohol Clin. Exp. Res. 22:1998;1713-1718.
41. Ren X., Kennedy A., Colletti L.M. CXC chemokine expression after stimulation with interferon-gamma in primary rat hepatocytes in culture. Shock. 17:2002;513-520.
42. Schoental R., Head M. Pathological changes in rats as a result of treatment with monocrotaline. Br. J. Cancer. 9:1955;229-237.
43. Schultze A.E., Roth R.A. Chronic pulmonary hypertension - the monocrotaline model and involvement of the hemostatic system. J. Toxicol. Environ. Health. 1:1998;271-346.
44. Snipes M.B., Barnett A.L., Harkema J.R., Hotchkiss J.A., Rebar A.H., Reddick L.J. Specific biological effects of an anti-rat PMN antiserum intraperitoneally injected into F344/N rats. Vet. Clin. Pathol. 24:1995;11-17.
45. Thornton A.J., Strieter R.M., Lindley I., Baggiolini M., Kunkel S.L. Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J. Immunol. 144:1990;2609-2613.
46. Yee S.B., Kinser S., Hill D.A., Barton C.C., Hotchkiss J.A., Harkema J.R., Ganey P.E., Roth R.A. Synergistic hepatotoxicity from coexposure to bacterial endotoxin and the pyrrolizidine alkaloid monocrotaline. Toxicol. Appl. Pharmacol. 166:2000;173-185.
47. Yee S.B., Ganey P.E., Roth R.A. The role of Kupffer cells and TNF-α in monocrotaline and bacterial lipopolysaccharide-induced liver injury. Toxicol. Sci. 71:2003;124-132.
48. Yee S.B., Hanumegowda U.M., Hotchkiss J.A., Ganey P.E., Roth R.A. Role of neutrophils in the synergistic liver injury from monocrotaline and bacterial lipopolysaccharide exposure. Toxicol. Sci. 72:2003;43-56.
49. Zhang P., Xie M., Zagorski J., Spitzer J.A. Attenuation of hepatic neutrophil sequestration by anti-CINC antibody in endotoxic rats. Shock. 4:1995;262-268.