Effect of sustained hypobaric hypoxia during maturation and aging on rat myocardium. I. Mechanical activity

Journal of Applied Physiology

Volumn 98, Issue 6, 2005, Pages 2363-2369

  La Padula, Pablo ^a   Costa, Lidia E ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Inst de Invest Cardiologicas   (Argentina)

Author keywords

Acclimatization; Heart contractility; High altitude; Hypoxia reoxygenation

Indexed keywords

AGING; ALTITUDE ACCLIMATIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; HEART LEFT VENTRICLE; HEART MUSCLE; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HEART PROTECTION; HEART WEIGHT; HEMATOCRIT; HYPOBARISM; HYPOXIA; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; WEIGHT GAIN;

ACCLIMATIZATION; AGING; ALTITUDE; ANIMALS; CELL HYPOXIA; MALE; MECHANOTRANSDUCTION, CELLULAR; MYOCARDIAL CONTRACTION; ORGAN SIZE; PAPILLARY MUSCLES; PRESSURE; RATS; RATS, WISTAR; STRESS, MECHANICAL; SURVIVAL;

EID: 19444378925     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00988.2004     Document Type: Article

References (48)

1. ATP channel. J Mol Cell Cardiol 31: 1821-1831, 1999.
2. Baker EJ, Boerboom LE, Olinger GN, and Baker JE. Tolerance of the developing heart to ischemia: impact of hypoxemia from birth. Am J Physiol Heart Circ Physiol 268: H1165-H1173, 1995.
3. Baker JE. Oxidative stress and adaptation of the infant heart to hypoxia and ischemia. Antioxid Redox Signal 6: 423-429, 2004.
4. Baker JE, Holman P, Kalyanaraman B, Griffith OW, and Pritchard KA Jr. Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production. Ann NY Acad Sci 874: 236-253, 1999.
5. Bartling B, Hilgefort C, Friedrich I, Silber RE, and Simm A. Cardioprotective determinants are conserved in aged human myocardium after ischemic preconditioning. FEBS Lett 555: 539-544, 2003.
6. Besse S, Assayag P, Delcayre C, Carre F, Cheav SL, Lecarpentier Y, and Swinghedauw B. Normal and hypertrophied senescent rat heart: mechanical and molecular characteristics. Am J Physiol Heart Circ Physiol 265: H183-H190, 1993.
7. Bolli R. The late phase of preconditioning. Circ Res 87: 972-983, 2000.
8. Boveris A, D'Amico G, Lores-Arnaiz S, and Costa LE. Enalapril increases mitochondrial nitric oxide synthase activity in heart and liver. Antioxid Redox Signal 5: 691-697, 2003.
9. Brown GC. NO says yes to mitochondria. Science 299: 838-839, 2003.
10. Bunn HF and Poyton RO. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839-885, 1996.
11. Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, and Semenza GL. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108: 79-85, 2003.
12. Costa LE. Hepatic cytochrome P-450 in rats submitted to chronic hypobaric hypoxia. Am J Physiol Cell Physiol 259: C654-C659, 1990.
13. Costa LE, Boveris A, Koch OR, and Taquini AC. Liver and heart mitochondria in rats submitted to chronic hypobaric hypoxia. Am J Physiol Cell Physiol 255: C123-C129, 1988.
14. Costa LE, La-Padula P, Lores-Arnaiz S, D'Amico G, Boveris A, Kurnjek ML, and Basso N. Long-term angiotensin II inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart. J Hypertens 20: 2487-2494, 2002.
15. Costa LE, Llesuy S, and Boveris A. Active oxygen species in the liver of rats submitted to chronic hypobaric hypoxia. Am J Physiol Cell Physiol 264: C1395-C1400, 1993.
16. Costa LE, Méndez G, and Boveris A. Oxygen dependence of mitochondrial function measured by high-resolution respirometry in long-term hypoxic rats. Am J Physiol Cell Physiol 273: C852-C858, 1997.
17. Costa LE, Martin IM, Macome JC, and Taquini AC. Effect of chronic hypobaric hypoxia on growth and body composition in the rat. Medicina (B Aires) 39: 604-610, 1979.
18. ATP channel activity during chronic myocardial hypoxia. Is cardioprotection mediated by improved bioenergetics? Circ Res 87: 915-921, 2000.
19. Fandrey J. Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression. Am J Physiol Regul Integr Comp Physiol 286: R977-R988, 2004.
20. Fenton RA, Dickson EW, Meyer TE, and Dobson JG Jr. Aging reduces the cardioprotective effect of ischemic preconditioning in the rat heart. J Mol Cell Cardiol 32: 1371-1375, 2000.
21. ATP channel blockade does not abolish increased RV tolerance to ischemia. Am J Physiol Heart Circ Physiol 286: H545-H551, 2004.
22. + channels in cardiac function and cardioprotection. Biochim Biophys Acta 1606: 1-21, 2003.
23. Giulivi C, Poderoso JJ, and Boveris A. Production of nitric oxide by mitochondria. J Biol Chem 273: 11038-11043, 1998.
24. ATP channels and myocardial preconditioning: an update. Am J Physiol Heart Circ Physiol 285: H921-H930, 2003.
25. Hare JM. Nitric oxide and excitation-contraction coupling. J Mol Cell Cardiol 35: 719-729, 2003.
26. Headrick JP. Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation. J Mol Cell Cardiol 30: 1415-1430, 1998.
27. Hrbasová M, Novotny J, Hejnová L, Kolár F, Neckár J, and Svoboda P. Altered myocardial Gs protein and adenyl cyclase signaling in rats exposed to chronic hypoxia and normoxic recovery. J Appl Physiol 94: 2423-2432, 2003.
28. Hurtado A. Some clinical aspects of life at high altitudes. Ann Intern Med 53: 247-258, 1960.
29. Kanai AJ, Pearce LL, Clemens PR, Birder LA, VanBibber MM, Choi SY, de Groat WC, and Peterson J. Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection. Proc Natl Acad Sci USA 98: 14126-14131, 2001.
30. Kolár F and Ostádal B. Molecular mechanisms of cardiac protection by adaptation to chronic hypoxia. Physiol Res 53: S3-S13, 2004.
31. ATP channels mediate cardioprotection in chronically hypoxic hearts. J Mol Cell Cardiol 33: 1041-1045, 2001.
32. Kumar GK and Klein JB. Analysis of expression and posttranslational modification of proteins during hypoxia. J Appl Physiol 96: 1178-1186, 2004.
33. Lacza Z, Puskar M, Figueroa JP, Zhang J, Rajapakse N, and Busija DW. Mitochondrial nitric oxide synthase is constitutively active and is functionally upregulated in hypoxia. Free Radic Biol Med 31: 1609-1615, 2001.
34. ATP channel. Am J Physiol Heart Circ Physiol 284: H299-H308, 2003.
35. ATP modulators on cardioprotection induced by chronic high altitude hypoxia in rats. Cardiovasc Res 55: 567-575, 2002.
36. Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, Bracale R, Valerio A, Francolini M, Moncada S, and Carruba MO. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299: 896-899, 2003.
37. Ostadal B, Ostadalova I, and Dhalla NS. Development of cardiac sensitivity to oxygen deficiency: comparative and ontogenetic aspects. Physiol Rev 79: 635-659, 1999.
38. Oxenham H and Sharpe N. Cardiovascular aging and heart failure. Eur J Heart Fail 5: 427-434, 2003.
39. Poderoso JJ, Peralta JG, Lisdero CL, Carreras MC, Radisic M, Schöpfer F, Cadenas E, and Boveris A. Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart. Am J Physiol Cell Physiol 274: C112-C119, 1998.
40. Schulman D, Latchman DS, and Yellon DM. Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 281: H1630-H1636, 2001.
41. 2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J Appl Physiol 96: 1173-1177, 2004.
42. Semenza GL and Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12: 5447-5454, 1992.
43. Shah AM and MacCarthy PA. Paracrine and autocrine effects of nitric oxide on myocardial function. Pharmacol Ther 86: 49-86, 2000.
44. Shi Y, Baker JE, Zhang C, Tweddell JS, Su J, and Pritchard KA Jr. Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. Circ Res 91: 300-306, 2002.
45. Shi Y, Pritchard K Jr, Holman P, Raflee P, Griffith O, Kalyanaraman B, and Baker JE. Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. Free Radic Biol Med 29: 695-703, 2000.
46. West JB. Acclimatization and adaptation: organ to cell. In: Response and Adaptation to Hypoxia, edited by Lahiri S, Cheraiak NS, and Fitzgerald RS. New York: Oxford University Press, 1991.
47. Xi L, Tekin D, Gursoy E, Salloum F, Levasseur JE, and Kukreja RC. Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia. Am J Physiol Heart Circ Physiol 283: H5-H12, 2002.
48. Zaobornyj T, Valdez LB, La Padula P, Costa LE, and Boveris A. Effect of sustained hypobaric hypoxia during maturation and aging on rat myocardium. II. mtNOS activity. J Appl Physiol 98: 2370-2375, 2005.