Receptor-targeting mechanisms of pain-causing toxins: How ow?

Toxicon

Volumn 60, Issue 3, 2012, Pages 254-264

  Bohlen, Christopher J ^a   Julius, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ASIC; Multimeric toxin; Multivalent toxin; Pain; TRPV1; Venom

Indexed keywords

ACID SENSING ION CHANNEL; RECEPTOR PROTEIN; TOXIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOTOXIN;

BIOCHEMICAL COMPOSITION; BURNING SENSATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DISEASE SEVERITY; ENVENOMATION; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NOCICEPTION; NOCICEPTIVE RECEPTOR; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS;

ACUTE PAIN; ANIMALS; BITES AND STINGS; GANGLIA, SENSORY; HUMANS; NERVE TISSUE PROTEINS; NOCICEPTORS; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PROTEINS; SODIUM CHANNELS; SOMATOSENSORY CORTEX; TRPV CATION CHANNELS; VENOMS;

EID: 84861737800     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.04.336     Document Type: Review

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