메뉴 건너뛰기




Volumn 451, Issue 1, 2005, Pages 143-150

Structure and function of TRPV1

Author keywords

Acid; Capsaicin; Desensitization; Heat; Phosphorylation; Sensitization; TRP channels; TRPV1

Indexed keywords

AMINO ACID; CAPSAICIN; LIPID; MEMBRANE PROTEIN; PROTON; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VANILLOID RECEPTOR;

EID: 26444511606     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-005-1457-8     Document Type: Review
Times cited : (374)

References (82)
  • 1
    • 0042734414 scopus 로고    scopus 로고
    • Activation of TRPV1 by the satiety factor oleoylethanolamide
    • Ahern GP (2003) Activation of TRPV1 by the satiety factor oleoylethanolamide. J Biol Chem 278:30429-30434
    • (2003) J Biol Chem , vol.278 , pp. 30429-30434
    • Ahern, G.P.1
  • 2
    • 0001951152 scopus 로고    scopus 로고
    • Extracellular protons both increase the activity and reduce the conductance of capsaicin-gated channels
    • Baumann TK, Martenson ME (2000) Extracellular protons both increase the activity and reduce the conductance of capsaicin-gated channels. J Neurosci 20:RC80
    • (2000) J Neurosci , vol.20
    • Baumann, T.K.1    Martenson, M.E.2
  • 3
    • 0023228204 scopus 로고
    • Capsaicin in the treatment of dermatologic disease
    • Bernstein JE (1987) Capsaicin in the treatment of dermatologic disease. Cutis 39:352-353
    • (1987) Cutis , vol.39 , pp. 352-353
    • Bernstein, J.E.1
  • 4
    • 0142059776 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
    • USA
    • Bhave G, Hu HJ, Glauner KS, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW 4th (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci USA 100:12480-12485
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 12480-12485
    • Bhave, G.1    Hu, H.J.2    Glauner, K.S.3    Zhu, W.4    Wang, H.5    Brasier, D.J.6    Oxford, G.S.7    Gereau IV, R.W.8
  • 5
    • 0037104657 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
    • Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW 4th (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35:721-731
    • (2002) Neuron , vol.35 , pp. 721-731
    • Bhave, G.1    Zhu, W.2    Wang, H.3    Brasier, D.J.4    Oxford, G.S.5    Gereau IV, R.W.6
  • 6
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: A molecular gateway to the pain pathway
    • Caterina MJ, Julius D (2001) The vanilloid receptor: a molecular gateway to the pain pathway. Annu Rev Neurosci 24:487-517
    • (2001) Annu Rev Neurosci , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 8
    • 0033166535 scopus 로고    scopus 로고
    • Specific involvement of PKC-ε in sensitization of the neuronal response to painful heat
    • Cesare P, Dekker LV, Sardini A, Parker PJ, McNaughton PA (1999) Specific involvement of PKC-ε in sensitization of the neuronal response to painful heat. Neuron 23:617-624
    • (1999) Neuron , vol.23 , pp. 617-624
    • Cesare, P.1    Dekker, L.V.2    Sardini, A.3    Parker, P.J.4    McNaughton, P.A.5
  • 9
    • 0031037164 scopus 로고    scopus 로고
    • Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex
    • Chevesich J, Kreuz AJ, Montell C (1997) Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron 18:95-105
    • (1997) Neuron , vol.18 , pp. 95-105
    • Chevesich, J.1    Kreuz, A.J.2    Montell, C.3
  • 10
    • 1542267774 scopus 로고    scopus 로고
    • Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain
    • Chou MZ, Mtui T, Gao YD, Kohler M, Middleton RE (2004) Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain. Biochemistry 43: 2501-2511
    • (2004) Biochemistry , vol.43 , pp. 2501-2511
    • Chou, M.Z.1    Mtui, T.2    Gao, Y.D.3    Kohler, M.4    Middleton, R.E.5
  • 11
    • 4544368241 scopus 로고    scopus 로고
    • The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
    • Chuang HH, Neuhausser WM, Julius D (2004) The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 43:859-869
    • (2004) Neuron , vol.43 , pp. 859-869
    • Chuang, H.H.1    Neuhausser, W.M.2    Julius, D.3
  • 13
    • 0347504835 scopus 로고    scopus 로고
    • TRP channels as cellular sensors
    • Clapham DE (2003) TRP channels as cellular sensors. Nature 426: 517-524
    • (2003) Nature , vol.426 , pp. 517-524
    • Clapham, D.E.1
  • 14
    • 2442468123 scopus 로고    scopus 로고
    • Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
    • Dai Y, Moriyama T, Higashi T, Togashi K, Kobayashi K, Yamanaka H, Tominaga M, Noguchi K (2004) Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J Neurosci 24:4293-4299
    • (2004) J Neurosci , vol.24 , pp. 4293-4299
    • Dai, Y.1    Moriyama, T.2    Higashi, T.3    Togashi, K.4    Kobayashi, K.5    Yamanaka, H.6    Tominaga, M.7    Noguchi, K.8
  • 16
    • 0029965156 scopus 로고    scopus 로고
    • Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
    • Docherty RJ, Yeats JC, Bevan S, Boddeke HW (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Arch 431:828-837
    • (1996) Pflugers Arch , vol.431 , pp. 828-837
    • Docherty, R.J.1    Yeats, J.C.2    Bevan, S.3    Boddeke, H.W.4
  • 17
    • 0029991047 scopus 로고    scopus 로고
    • Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit
    • Ehlers MD, Zhang S, Bernhadt JP, Huganir RL (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell 84:745-755
    • (1996) Cell , vol.84 , pp. 745-755
    • Ehlers, M.D.1    Zhang, S.2    Bernhadt, J.P.3    Huganir, R.L.4
  • 18
  • 20
    • 0034659519 scopus 로고    scopus 로고
    • Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)
    • Lond
    • Gunthorpe MJ, Harries MH, Prinjha RK, Davis JB, Randall A (2000) Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1). J Physiol (Lond) 525:747-759
    • (2000) J Physiol , vol.525 , pp. 747-759
    • Gunthorpe, M.J.1    Harries, M.H.2    Prinjha, R.K.3    Davis, J.B.4    Randall, A.5
  • 21
    • 0038311985 scopus 로고    scopus 로고
    • Proteins modulating TRP channel function
    • Harteneck C (2003) Proteins modulating TRP channel function. Cell Calcium 33:303-310
    • (2003) Cell Calcium , vol.33 , pp. 303-310
    • Harteneck, C.1
  • 23
    • 0036758636 scopus 로고    scopus 로고
    • Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: Potential mechanism for thermal hyperalgesia
    • Hu HJ, Bhave G, Gereau RW 4th (2002) Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia. J Neurosci 22:7444-7452
    • (2002) J Neurosci , vol.22 , pp. 7444-7452
    • Hu, H.J.1    Bhave, G.2    Gereau IV, R.W.3
  • 24
    • 0032546013 scopus 로고    scopus 로고
    • Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ
    • Huang CL, Feng S, Hilgemann DW (1998) Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ. Nature 391:803-806
    • (1998) Nature , vol.391 , pp. 803-806
    • Huang, C.L.1    Feng, S.2    Hilgemann, D.W.3
  • 28
    • 0036183319 scopus 로고    scopus 로고
    • Molecular basis for species-specific sensitivity to "hot" chili peppers
    • Jordt SE, Julius D (2002) Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108:421-430
    • (2002) Cell , vol.108 , pp. 421-430
    • Jordt, S.E.1    Julius, D.2
  • 29
    • 0041878279 scopus 로고    scopus 로고
    • Lessons from peppers and peppermint: The molecular logic of thermosensation
    • Jordt SE, McKemy DD, Julius D (2003) Lessons from peppers and peppermint: the molecular logic of thermosensation. Curr Opin Neurobiol 13:487-492
    • (2003) Curr Opin Neurobiol , vol.13 , pp. 487-492
    • Jordt, S.E.1    McKemy, D.D.2    Julius, D.3
  • 30
    • 0034608878 scopus 로고    scopus 로고
    • Acid potentiation of the capsaicin receptor determined by a key extracellular site
    • USA
    • Jordt SE, Tominaga M, Julius D (2000) Acid potentiation of the capsaicin receptor determined by a key extracellular site. Proc Natl Acad Sci USA 97:8134-8139
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 8134-8139
    • Jordt, S.E.1    Tominaga, M.2    Julius, D.3
  • 31
  • 34
    • 0036301043 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated ion channels
    • Kaupp UB, Seifert R (2002) Cyclic nucleotide-gated ion channels. Physiol Rev 82:769-824
    • (2002) Physiol Rev , vol.82 , pp. 769-824
    • Kaupp, U.B.1    Seifert, R.2
  • 37
    • 0030956114 scopus 로고    scopus 로고
    • The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons
    • Koplas PA, Rosenberg RL, Oxford GS (1997) The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons. J Neurosci 17:3525-3537
    • (1997) J Neurosci , vol.17 , pp. 3525-3537
    • Koplas, P.A.1    Rosenberg, R.L.2    Oxford, G.S.3
  • 38
    • 0035889970 scopus 로고    scopus 로고
    • Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation
    • Kuzhikandathil EV, Wang H, Szabo T, Morozova N, Blumberg PM, Oxford GS (2001) Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation. J Neurosci 21:8697-8706
    • (2001) J Neurosci , vol.21 , pp. 8697-8706
    • Kuzhikandathil, E.V.1    Wang, H.2    Szabo, T.3    Morozova, N.4    Blumberg, P.M.5    Oxford, G.S.6
  • 39
    • 0029880452 scopus 로고    scopus 로고
    • 2+ dependence in rat trigeminal ganglion cells
    • 2+ dependence in rat trigeminal ganglion cells. J Neurophysiol 75:1503-1514
    • (1996) J Neurophysiol , vol.75 , pp. 1503-1514
    • Liu, L.1    Simon, S.A.2
  • 40
    • 0030070940 scopus 로고    scopus 로고
    • Capsaicin activated currents in rat dorsal root ganglion cells
    • Liu L, Wang Y, Simon SA (1996) Capsaicin activated currents in rat dorsal root ganglion cells. Pain 64:191-195
    • (1996) Pain , vol.64 , pp. 191-195
    • Liu, L.1    Wang, Y.2    Simon, S.A.3
  • 41
    • 0025897177 scopus 로고
    • Capsaicin and primary afferent neurons: From basic science to human therapy?
    • Maggi CA (1991) Capsaicin and primary afferent neurons: from basic science to human therapy? J Auton Nerv Syst 33:1-14
    • (1991) J Auton Nerv Syst , vol.33 , pp. 1-14
    • Maggi, C.A.1
  • 42
    • 1642394771 scopus 로고    scopus 로고
    • Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels
    • Mandadi S, Numazaki M, Tominaga M, Bhat MB, Armati PJ, Roufogalis BD (2004) Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels. Cell Calcium 35:471-478
    • (2004) Cell Calcium , vol.35 , pp. 471-478
    • Mandadi, S.1    Numazaki, M.2    Tominaga, M.3    Bhat, M.B.4    Armati, P.J.5    Roufogalis, B.D.6
  • 43
    • 0346118925 scopus 로고    scopus 로고
    • Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway
    • Mohapatra DP, Nau C (2003) Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. J Biol Chem 278:50080-50090
    • (2003) J Biol Chem , vol.278 , pp. 50080-50090
    • Mohapatra, D.P.1    Nau, C.2
  • 44
    • 0038721194 scopus 로고    scopus 로고
    • A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents
    • Mohapatra DP, Wang SY, Wang GK, Nau C (2003) A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents. Mol Cell Neurosci 23:314-324
    • (2003) Mol Cell Neurosci , vol.23 , pp. 314-324
    • Mohapatra, D.P.1    Wang, S.Y.2    Wang, G.K.3    Nau, C.4
  • 45
    • 0030218118 scopus 로고    scopus 로고
    • Calmodulin regulation of cyclic-nucleotide-gated channels
    • Molday RS (1996) Calmodulin regulation of cyclic-nucleotide-gated channels. Curr Opin Neurobiol 6:445-452
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 445-452
    • Molday, R.S.1
  • 46
    • 33644875032 scopus 로고    scopus 로고
    • The TRP superfamily of cation channels
    • Montell C (2005) The TRP superfamily of cation channels. Sci STKE 2005:re3
    • (2005) Sci STKE , vol.2005
    • Montell, C.1
  • 47
    • 0024642547 scopus 로고
    • Molecular characterization of the Drosophilatrp locus: A putative integral membrane protein required for phototransduction
    • Montell C, Rubin GM (1989) Molecular characterization of the Drosophilatrp locus: a putative integral membrane protein required for phototransduction. Neuron 2:1313-1323
    • (1989) Neuron , vol.2 , pp. 1313-1323
    • Montell, C.1    Rubin, G.M.2
  • 52
    • 0037144453 scopus 로고    scopus 로고
    • Protein kinase Cα is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways
    • Olah Z, Karai L, Iadarola MJ (2002) Protein kinase Cα is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways. J Biol Chem 277:35752-35759
    • (2002) J Biol Chem , vol.277 , pp. 35752-35759
    • Olah, Z.1    Karai, L.2    Iadarola, M.J.3
  • 55
    • 2342439775 scopus 로고    scopus 로고
    • Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1
    • Phillips E, Reeve A, Bevan S, McIntyre P (2004) Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1. J Biol Chem 279:17165-17172
    • (2004) J Biol Chem , vol.279 , pp. 17165-17172
    • Phillips, E.1    Reeve, A.2    Bevan, S.3    McIntyre, P.4
  • 56
    • 0033178406 scopus 로고    scopus 로고
    • A study of the voltage dependence of capsaicin-activated membrane currents in rat sensory neurones before and after acute desensitization
    • Lond
    • Piper AS, Yeats JC, Bevan S, Docherty RJ (1999) A study of the voltage dependence of capsaicin-activated membrane currents in rat sensory neurones before and after acute desensitization. J Physiol (Lond) 518:721-733
    • (1999) J Physiol , vol.518 , pp. 721-733
    • Piper, A.S.1    Yeats, J.C.2    Bevan, S.3    Docherty, R.J.4
  • 57
    • 0037112377 scopus 로고    scopus 로고
    • Single-channel properties of native and cloned rat vanilloid receptors
    • Lond
    • Premkumar LS, Agarwal S, Steffen D (2002) Single-channel properties of native and cloned rat vanilloid receptors. J Physiol (Lond) 545:107-117
    • (2002) J Physiol , vol.545 , pp. 107-117
    • Premkumar, L.S.1    Agarwal, S.2    Steffen, D.3
  • 58
    • 0034700494 scopus 로고    scopus 로고
    • Induction of vanilloid receptor channel activity by protein kinase C
    • Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985-990
    • (2000) Nature , vol.408 , pp. 985-990
    • Premkumar, L.S.1    Ahern, G.P.2
  • 59
    • 1342344077 scopus 로고    scopus 로고
    • Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptor
    • Premkumar LS, Qi ZH, Van Buren J, Raisinghani M (2004) Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptor. J Neurophysiol 91:1442-1449
    • (2004) J Neurophysiol , vol.91 , pp. 1442-1449
    • Premkumar, L.S.1    Qi, Z.H.2    Van Buren, J.3    Raisinghani, M.4
  • 60
    • 0037799198 scopus 로고    scopus 로고
    • A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity
    • Prescott ED, Julius D (2003) A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300:1284-1288
    • (2003) Science , vol.300 , pp. 1284-1288
    • Prescott, E.D.1    Julius, D.2
  • 63
    • 0012457490 scopus 로고    scopus 로고
    • Hyperpolarization-activated cation currents: From molecules to physiological function
    • Robinson RB, Siegelbaum SA (2003) Hyperpolarization-activated cation currents: from molecules to physiological function. Annu Rev Physiol 65:453-480
    • (2003) Annu Rev Physiol , vol.65 , pp. 453-480
    • Robinson, R.B.1    Siegelbaum, S.A.2
  • 65
    • 0036092076 scopus 로고    scopus 로고
    • The TRPM7 channel is inactivated by PIP(2) hydrolysis
    • Runnels LW, Yue L, Clapham DE (2002) The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol 4:329-336
    • (2002) Nat Cell Biol , vol.4 , pp. 329-336
    • Runnels, L.W.1    Yue, L.2    Clapham, D.E.3
  • 67
    • 0030665081 scopus 로고    scopus 로고
    • Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo
    • Scott K, Sun Y, Beckingham K, Zuker CS (1997) Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo. Cell 91:375-383
    • (1997) Cell , vol.91 , pp. 375-383
    • Scott, K.1    Sun, Y.2    Beckingham, K.3    Zuker, C.S.4
  • 68
    • 0032792551 scopus 로고    scopus 로고
    • The ankyrin repeat: A diversity of interactions on a common structural framework
    • Sedgwick SG, Smerdon SJ (1999) The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem Sci 24: 311-316
    • (1999) Trends Biochem Sci , vol.24 , pp. 311-316
    • Sedgwick, S.G.1    Smerdon, S.J.2
  • 70
    • 0036310523 scopus 로고    scopus 로고
    • Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1
    • Sugiura T, Tominaga M, Katsuya H, Mizumura K (2002) Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J Neurophysiol 88:544-548
    • (2002) J Neurophysiol , vol.88 , pp. 544-548
    • Sugiura, T.1    Tominaga, M.2    Katsuya, H.3    Mizumura, K.4
  • 71
    • 0032970173 scopus 로고    scopus 로고
    • Vanilloid (capsaicin) receptors and mechanisms
    • Szallasi A, Blumberg PM (1999) Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-212
    • (1999) Pharmacol Rev , vol.51 , pp. 159-212
    • Szallasi, A.1    Blumberg, P.M.2
  • 74
    • 0035810934 scopus 로고    scopus 로고
    • Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
    • USA
    • Tominaga M, Wada M, Masu M (2001) Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia. Proc Natl Acad Sci USA 98: 6951-6956
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 6951-6956
    • Tominaga, M.1    Wada, M.2    Masu, M.3
  • 76
    • 4043077669 scopus 로고    scopus 로고
    • The principle of temperature-dependent gating in cold- And heat-sensitive TRP channels
    • Voets T, Droogmans G, Wissenbach U, Janssens A, Flockerzi V, Nilius B (2004) The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature 430:748-754
    • (2004) Nature , vol.430 , pp. 748-754
    • Voets, T.1    Droogmans, G.2    Wissenbach, U.3    Janssens, A.4    Flockerzi, V.5    Nilius, B.6
  • 77
    • 0037198410 scopus 로고    scopus 로고
    • Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1
    • Vyklicky L, Lyfenko A, Susankova K, Teisinger J, Vlachova V (2002) Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1. Neuroscience 111:435-441
    • (2002) Neuroscience , vol.111 , pp. 435-441
    • Vyklicky, L.1    Lyfenko, A.2    Susankova, K.3    Teisinger, J.4    Vlachova, V.5
  • 79
    • 0034610391 scopus 로고    scopus 로고
    • The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat
    • USA
    • Welch JM, Simon SA, Reinhart PH (2000) The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat. Proc Natl Acad Sci USA 97:13889-13894
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 13889-13894
    • Welch, J.M.1    Simon, S.A.2    Reinhart, P.H.3
  • 80
    • 0032142987 scopus 로고    scopus 로고
    • Calmodulin mediates calcium-dependent inactivation of N-methyl-D-aspartate receptors
    • Zhang S, Ehlers MD, Bernhardt JP, Su CT, Huganir RL (1998) Calmodulin mediates calcium-dependent inactivation of N-methyl-D-aspartate receptors. Neuron 21:443-453
    • (1998) Neuron , vol.21 , pp. 443-453
    • Zhang, S.1    Ehlers, M.D.2    Bernhardt, J.P.3    Su, C.T.4    Huganir, R.L.5
  • 81
    • 0345465665 scopus 로고    scopus 로고
    • Calmodulin supports both inactivation and facilitation of L-type calcium channels
    • Zuhlke RD, Pitt GS, Deisseroth K, Tsien RW, Reuter H (1999) Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature 399:159-162
    • (1999) Nature , vol.399 , pp. 159-162
    • Zuhlke, R.D.1    Pitt, G.S.2    Deisseroth, K.3    Tsien, R.W.4    Reuter, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.