A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

Nature

Volumn 430, Issue 6996, 2004, Pages 232-235

  Lee, Seok Yong ^a   MacKinnon, Roderick ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; HYDROPHOBICITY; PROTEINS; SENSORS; TOXIC MATERIALS;

ION CHANNELS; VOLTAGE SENSORS;

BIOLOGICAL MEMBRANES;

ION CHANNEL; POTASSIUM CHANNEL; POTASSIUM ION; SPIDER VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE SENSOR TOXIN 1;

TOXICOLOGY;

ARTICLE; BINDING AFFINITY; HYDROPHOBICITY; LIPID MEMBRANE; MEMBRANE ELECTROPHYSIOLOGY; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SPIDER; TOXIN ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHYSIOLOGY; FLUORESCENCE; ION CHANNEL GATING; MEMBRANE LIPIDS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNELS, VOLTAGE-GATED; SPIDER VENOMS; TRYPTOPHAN;

ANIMALIA; ARANEAE; GRAMMOSTOLA SPATULATA;

EID: 3142580385     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02632     Document Type: Article

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