Euphorbium: Modern research on its active principle, resiniferatoxin, revives an ancient medicine

Life Sciences

Volumn 60, Issue 10, 1997, Pages 681-696

  Appendino, Giovanni ^a   Szallasi, Arpad ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Capsaicin; Euphorbium; Resiniferatoxin; Vanilloid receptors

Indexed keywords

CAPSAICIN; CAPSAICIN DERIVATIVE; EUPHORBIA EXTRACT; LATEX; MEMBRANE RECEPTOR; NEUROPEPTIDE; RESINIFERATOXIN; VANILLOID RECEPTOR;

BINDING SITE; CLINICAL TRIAL; DESENSITIZATION; DIABETIC NEUROPATHY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; HISTORY OF MEDICINE; HUMAN; NEUROGENIC INFLAMMATION; NONHUMAN; PAIN; POSTHERPETIC NEURALGIA; REVIEW; SENSORY NERVE CELL; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION;

EUPHORBIA; EUPHORBIA RESINIFERA; EUPHORBIUM; ROMAN;

EID: 0031025655     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(96)00567-X     Document Type: Short Survey

References (91)

1. A. TSCHIRCH and D. STOCK, Die Harze, 1635-1670, Borntraeger Verlag, Berlin (1935).
2. L. TURNER. Euphorbias, Batsford Ltd, London (1995).
3. A. BENEDICENTI, Malati, Medici e Farmacisti, 185-190, Hoepli, Milano (1947).
4. H. HULLEMAN, De Vita et Scriptis Jubae, Utrecht (1845).
5. A. TSCHIRCH, Handbuch der Pharmacognosie, Vol. III, 1167-1172, Tauchnitz Verlag, Leipzig (1923).
6. A. GOERLITZ, Jubae II Regis Mauritaniae, Vita et Fragmenta, Vol. I, Breslaw (1849); Vol. II, Breslaw (1862).
7. A. GOERLITZ, Jubae II Regis Mauritaniae, Vita et Fragmenta, Vol. I, Breslaw (1849); Vol. II, Breslaw (1862).
8. GAIUS PLINIUS SECUNDUS, Naturalis Historia, V. 16; X, 1; XXV, 38; XXV, 78.
9. GAIUS PLINIUS SECUNDUS, Naturalis Historia, V. 16; X, 1; XXV, 38; XXV, 78.
10. GAIUS PLINIUS SECUNDUS, Naturalis Historia, V. 16; X, 1; XXV, 38; XXV, 78.
11. GAIUS PLINIUS SECUNDUS, Naturalis Historia, V. 16; X, 1; XXV, 38; XXV, 78.
12. P. SANGIORGIO, Istoria delle piante medicate, 588, Milano (1809).
13. SCRIBONIUS LARGUS, Compositions Medicamentorum, circa 1th century A.D.
14. QUINTUS SERENUS (SAMMONICUS), Liber medicinalis, LV, 1000-1001.
15. DIOSCORIDES, De Materia Medica, III, 86.
16. S.B. CHRISTENSEN and K. SCHAUMBURG, J. Org. Chem. 48 396 (1983).
17. Leide Rijksuniversiteitsbibliothek, ar 289, f 132 recto (dated 1083).
18. Bibliotheca Universitaria di Bologna, ar 1954, f 160 recto (dated 1244).
19. P. A. MATTHIOLUS, Pedacio Dioscorides, XC, 538 (1544).
20. Farmacopea Italiana, Vol. II, 1061, Torino.
21. Pharmacopée Universelle, 602, Baillière, Paris (1840).
22. M. GEOFFROY, Traité de Matière Médicale, Vol. IV, 210, Paris (1743).
23. Merck's Index, 3rd Edition, Merck & Co, Rahway, NJ (1920).
24. Mercks 's Index, 4th Edition, Merck & Co, Rahway, NJ (1930).
25. P. MELIUS, Herbarium, Heltai Gáspárnè mühelye (in Hungarian), Kolozsvár (1578).
26. Medicamenta, VI Edizione, Vol. IV, 3447, Cooperativa Farmaceutica, Milano (1965).
27. F.V. MÉRAT and A.J. DE LENS, Dictionnaire Universel de Matière Médicale, 184-186, Ballière, Paris (1834).
28. H. JACKSON, Account of the empire of Morocco and the district of Suse, 81, London (1809).
29. F.A. FLUECKIGER and D. HANBURY, Histoire des drogues d'origine végétale, 304, Odoin, Paris (1878).
30. O.C. BERG and H. SCHMIDT, Offizinelle Gewächse IV 24 (1863).
31. E. HECKER and S. SOSATH, CLB Chem. Lab. Betr. 1 42 (1991).
32. M. HERGENHAHN, W. ADOLPH and E. HECKER, Tetrahedron Lett. 19 1595-1598 (1975).
33. M. HERGENHAHN, PhD Thesis, University of Heidelberg (1974).
34. S. ZAYED, B. SORG and E. HECKER, Planta Med. 65-69 (1984).
35. P.M. BLUMBERG, Cancer Res. 48 1-8 (1988).
36. K.R. GUSTAFSON, J.H. CARDELLINA II, J.B. MCMAHON, R.J. GULAKOWSKI, J. ISHITOYA, Z. SZALLASI, N.B. LEWIN, P.M. BLUMBERG, O.S. WEISLOW, J.A. BEUTLER, R.W. BUCKHIET JR, G.C. CRAGG, P.A. COX, J.P. BADER and M.R. BOYD, J. Med. Chem. 35 1978-1986 (1992).
37. P.M. BLUMBERG, A. SZALLASI and G. ACS, Capsaicin in the Study of Pain, J.N. Wood (ed), 45-60, Academic Press, New York (1993).
38. P.E. DRIEDGER and P.M. BLUMBERG, Cancer Res. 40 1400-1404 (1980).
39. P.E. DRIEDGER and P.M. BLUMBERG, Proc. Natl. Acad. Sci. USA 77 567-571 (1980).
40. H. ZUR HAUSEN, G.W. BORNKAMM, R.J. SCHMIDT and E. HECKER, Proc. Natl. Acad. Sci. USA 76782-785 (1979).
41. A. SZALLASI and P.M. BLUMBERG, Neuroscience 30 515-520 (1989).
42. A. SZALLASI, Gen. Pharmacol. 25 223-243 (1994).
43. A. SZALLASI, Acta Physiol. Scand. 155 (suppl. 629) 1-68 (1995).
44. P. HOLZER, Pharmacol. Rev. 43 144-201 (1991).
45. N. JANCSÓ, Pharmacology of Pain, K. Lin, D. Armstrong and E.G. Pardo (eds), 33-55, Pergamon Press, Oxford (1968).
46. G. JANCSÓ, E. KIRALY and A. JANCSÓ-GÁBOR, Nature 270 741-743 (1978).
47. A. SZALLASI and P.M. BLUMBERG, Life Sci. 47 1399-1408 (1990).
48. C.A. MAGGI, R. PATACCHINI, M. TRAMONTANA, R. AMANN, S. GIULIANI and P. SANTICIOLOI, Neuroscience 37 531-539 (1990).
49. A. SZALLASI, M. JONASSOHN, G. ÁCS, T. BÍRÓ, P. ÁCS, P.M. BLUMBERG and O. STERNER, Br. J. Pharmacol., in press.
50. A. SZALLASI and P.M. BLUMBERG, Brain Res. 524 106-111 (1990).
51. S. BEVAN, S. HOTHI, G. HUGHES, I.F. JAMES, H.P. RANG, K. SHAH, C.S.J. WALPOLE and J.C. YEATS, Br. J. Pharmacol. 107 544-552 (1992).
52. G. ACS, M. PALKOVITS and P.M. BLUMBERG, Life Sci. 55 1017-1026 (1994).
53. A. SZALLASI, S. NILSSON, T. FARKAS-SZALLASI, P.M. BLUMBERG, T. HÖKFELT and J.M. LUNDBERG, Brain Res. 703 175-183 (1995).
54. L. LIU and S.A. SIMON, J. Neurophysiol. 75 1503-1514 (1996).
55. G. ACS, J. LEE, V.E. MARQUEZ and P.M. BLUMBERG, Mol. Brain Res. 35 173-182 (1996).
56. C.D. GRIFFITHS, T.P.D. ELDERSHAW, D.P. GERATHY, J.L. HALL and E.Q. COLQUHOUN, Life Sci. 59 105-117 (1996).
57. A. DICKINSON, C. HUGHES, A. RUEFF and A. DRAY, Pain 43 353-362 (1990).
58. G. APPENDINO, G. CRAVOTTO, G. PALMISANO, R. ANNUNZIATA and A. SZALLASI. J. Med. Chem. 393123-3131 (1996).
59. S. BEVAN and J. SZOLCSANYI, Trends Pharmacol. Sci. 11 330-333 (1990).
60. S.J. BEVAN and R.J. DOCHERTY, Capsaicin in the Study of Pain, J.N. Wood (ed), 27-44, Academic Press, New York (1993).
61. J.C.G. COLERIDGE and H.M. COLERIDGE, Rev. Physiol. Biochem. Pharmacol. 99 1-110 (1984).
62. A. JANCSÓ-GÁBOR, J. SZOLCSÁNYI and N. JANCSÓ, J. Physiol. (London) 206 495-507 (1970).
63. M. SZIKSZAY and E.D. LONDON, Neuroscience 25 917-923 (1988).
64. S. RITTER and T.T. DINH, Capsaicin in the Study of Pain, J.N. Wood (ed), 105-138, Academic Press, New York (1993).
65. A. SZALLASI and P.M. BLUMBERG, Life Sci. 48 1863-1869 (1991).
66. U. OH, S.W. HWANG and D. KIM, J. Neurosci. 16 1659-1667 (1996).
67. K. MADERSPACH and CS. FAJSZI, Biochim. Biophys. Acta 692 469-478 (1982).
68. A. SZALLASI, G. ACS, G. CRAVOTTO, P.M. BLUMBERG, J.M. LUNDBERG and G. APPENDINO, Eur. J. Pharmacol. 299 221-228 (1996).
69. A. SZALLASI, P.M. BLUMBERG and J.M. LUNDBERG, Eur. J. Pharmacol. Mol. Pharmacol. Section 289 181-187 (1995).
70. S. BEVAN and G. GEPPETTI, Trends Neurosci. 17 509-512 (1994).
71. G. ACS, M. PALKOVITS and P.M. BLUMBERG, J. Pharmacol. Exp. Ther. 274 1090-1098 (1995).
72. A. SZALLASI, P.M. BLUMBERG, T. HÖKFELT and J.M. LUNDBERG, Eur. J. Pharmacol. 298 321-327 (1996).
73. R. AMANN and C.A. MAGGI, Life Sci. 49 849-856 (1991).
74. R.J. DOCHERTY, B. ROBERTSON and S. BEVAN, Neuroscience 40 513-521 (1991).
75. J.S. HARVEY, C. DAVIS, I.F. JAMES and G.M. BURGESS, J. Neurochem. 65 1309-1317 (1995).
76. J.C. YEATS, H.W.G.M. BODDEKE and R.J. DOCHERTY, Br. J. Pharmacol. 107 (Suppl) 238P (1992).
77. G. JANCSÓ, E. KIRALY, A. SZEBENI, L. TÓTH, E. BÁCSY, F. JOÓ and Á. PÁRDUCZ, Brain Res. 295211-216 (1984).
78. J. SZOLCSÁNYI, Capsaicin in the Study of Pain, J.N. Wood (ed), 1-26, Academic Press, New York (1993).
79. T.M. JESSELL, L.L. IVERSEN and A.C. CUELLO, Brain Res. 152 183-188 (1978).
80. J.E. KRAUSE, J.M. CHIRGWIN, M.S. CARTER, Z.S. XU and A.D. HERSHEY, Proc. Natl. Acad. Sci. USA 84 881-885 (1987).
81. R.M. LINDSAY and A.J. HARMAR, Nature 337 362-364 (1989).
82. R. LEVI-MONTALCINI and P.U. ANGELETTI, Physiol. Rev. 48 534-569 (1968).
83. M.S. MILLER, S.H. BUCK, I.G. SIPES, H.I. YAMAMURA and T.F. BURKS, Brain Res. 250 193-196 (1982).
84. G.L. LEWIN and L.M. MENDELL, Trends Neurosci. 16 353-359 (1993).
85. R. BARANOWSKI, B. LYNN and A. PINI, Br. J. Pharmacol. 89 267-276 (1986).
86. A. SZALLASI, X.-J. XU, T. FARKAS-SZALLASI, J.M. LUNDBERG, T. HÖKFELT and Z. WIESENFELD-HALLIN, 8th World Congress on Pain, Vancouver, BC, Abstracts, 122, IASP Press, Seattle (1996).
87. A. SZALLASI, J. Peripheral Nerv. Syst. 1 1-13 (1996).
88. T. HÖKFELT, X. ZHANG and Z. WIESENFELD-HALLIN, Trends Neurosci. 17 22-30 (1994).
89. M. YANAGISAWA, N. YAGI, M. OTSUKA, C. YANAIHARA and N. YANAIHARA, Neurosci. Lett. 70278-282 (1986).
90. J. SZOLCSÁNYI, A. SZALLASI, Z. SZALLASI, F. JOÓ and P.M. BLUMBERG, J. Pharmacol. Exp. Ther. 255923-928 (1990).
91. A. SZALLASI, N.E. LEWIN and P.M. BLUMBERG, J. Pharmacol. Exp. Ther. 262 883-888 (1992).