CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes

Journal of Clinical Investigation

Volumn 116, Issue 9, 2006, Pages 2366-2377

  Andrade, Rosa M ^a   Wessendarp, Matthew ^a   Gubbels, Marc Jan ^b,d   Striepen, Boris ^b   Subauste, Carlos S ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BOSTON COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CD40 LIGAND; GAMMA INTERFERON; LYSOSOME ENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; RAB7 PROTEIN;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; AUTOPHAGY; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL STIMULATION; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; HUMAN; HUMAN CELL; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXOPLASMA GONDII;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD40; AUTOPHAGY; CELL CULTURE TECHNIQUES; CHLORAMPHENICOL O-ACETYLTRANSFERASE; HUMANS; INTERFERON TYPE II; LYSOSOMES; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; T-LYMPHOCYTES; TOXOPLASMA; TOXOPLASMOSIS; VACUOLES;

EID: 33748331335     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI28796     Document Type: Article

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