Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection

Autophagy

Volumn 5, Issue 7, 2009, Pages 1026-1029

  English, Luc ^a   Chemali, Magali ^a   Desjardins, Michel ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Autophagosome; Autophagy; HSV 1; Infection; MHC class I; T lymphocyte

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS ANTIGEN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIGEN PRESENTATION; AUTOPHAGY; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HYDROLYSIS; INNATE IMMUNITY; MACROPHAGE; NONHUMAN; PHAGOSOME; PROTEIN TARGETING; REVIEW;

HERPES; HUMAN HERPESVIRUS 1;

EID: 70349641036     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.7.9163     Document Type: Review

References (18)

1. Kloetzel PM. Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII. Nat Immunol 2004; 5:661-669
2. Kurts C, Heath WR, Carbone FR, Allison J, Miller JF, Kosaka H. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med 1996; 184:923-930 (Pubitemid 26313550)
3. Garin J, Diez R, Kieffer S, Dermine JF, Duclos S, Gagnon E, et al. The phagosome proteome: insight into phagosome functions. J Cell Biol 2001; 152:165-180
4. Gagnon E, Duclos S, Rondeau C, Chevet E, Cameron PH, Steele-Mortimer O, et al. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell 2002; 110:119-131 (Pubitemid 34874611)
5. Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med 2009; 206:399-410.
6. Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 2003; 425:397-402. (Pubitemid 37187268)
7. Grotzke JE, Harriff MJ, Siler AC, Nolt D, Delepine J, Lewinsohn DA, Lewinsohn DM. The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. PLoS Pathog 2009; 5:1000374.
8. Houde M, Bertholet S, Gagnon E, Brunet S, Goyette G, Laplante A, et al. Phagosomes are competent organelles for antigen cross-presentation. Nature 2003; 425:402-406 (Pubitemid 37187269)
9. Ackerman AL, Kyritsis C, Tampe R, Cresswell P. Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci USA 2003; 100:12889-12894 (Pubitemid 37339995)
10. Burgdorf S, Scholz C, Kautz A, Tampe R, Kurts C. Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation. Nat Immunol 2008; 9:558-566 (Pubitemid 351560525)
11. Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007; 7:767-777 (Pubitemid 47480305)
12. Paludan C, Schmid D, Landthaler M, Vockerodt M, Kube D, Tuschl T, Munz C. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 2005; 307:593-596 (Pubitemid 40165684)
13. English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol 2009.
14. Taylor MP, Kirkegaard K. Modification of cellular autophagy protein LC3 by poliovirus. J Virol 2007; 81:12543-12553 (Pubitemid 350085868)
15. Orvedahl A, Alexander D, Talloczy Z, Sun Q, Wei Y, Zhang W, et al. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 2007; 1:23-35. (Pubitemid 46506007)
16. Alexander DE, Ward SL, Mizushima N, Levine B, Leib DA. Analysis of the role of autophagy in replication of herpes simplex virus in cell culture. J Virol 2007; 81:12128-12134 (Pubitemid 350085828)
17. Simonsen A, Stenmark H. Self-eating from an ER-associated cup. J Cell Biol 2008; 182:621-622
18. Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701.