-
1
-
-
0033592653
-
Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction
-
Ahn J, Murphy M, Kratowicz S, Wang A, Levine AJ, George DL (1999) Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction. Oncogene 18: 5954-5958
-
(1999)
Oncogene
, vol.18
, pp. 5954-5958
-
-
Ahn, J.1
Murphy, M.2
Kratowicz, S.3
Wang, A.4
Levine, A.J.5
George, D.L.6
-
2
-
-
0033572417
-
Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation
-
Alarcon R, Koumenis C, Geyer RK, Maki CG, Giaccia AJ (1999) Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation. Cancer Res 59: 6046-6051
-
(1999)
Cancer Res
, vol.59
, pp. 6046-6051
-
-
Alarcon, R.1
Koumenis, C.2
Geyer, R.K.3
Maki, C.G.4
Giaccia, A.J.5
-
3
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxiainducible factor 1alpha
-
An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM (1998) Stabilization of wild-type p53 by hypoxiainducible factor 1alpha. Nature 392: 405-408
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
4
-
-
0033028043
-
The role of p53 in tumour suppression: Lessons from mouse models
-
Attardi LD, Jacks T (1999) The role of p53 in tumour suppression: lessons from mouse models. Cell Mol Life Sci 55: 48-63
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 48-63
-
-
Attardi, L.D.1
Jacks, T.2
-
5
-
-
0034654623
-
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family
-
Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW, Jacks T (2000) PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes Dev 14: 704-718
-
(2000)
Genes Dev
, vol.14
, pp. 704-718
-
-
Attardi, L.D.1
Reczek, E.E.2
Cosmas, C.3
Demicco, E.G.4
McCurrach, M.E.5
Lowe, S.W.6
Jacks, T.7
-
6
-
-
0033965487
-
P53 mutants have selective dominant-negative effects on apoptosis but not growth arrest in human cancer cell lines
-
Aurelio ON, Kong XT, Gupta S, Stanbridge EJ (2000) p53 mutants have selective dominant-negative effects on apoptosis but not growth arrest in human cancer cell lines. Mol Cell Biol 20: 770-778
-
(2000)
Mol Cell Biol
, vol.20
, pp. 770-778
-
-
Aurelio, O.N.1
Kong, X.T.2
Gupta, S.3
Stanbridge, E.J.4
-
7
-
-
66349121718
-
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
-
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssegur J, Mazure NM (2009) Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 29: 2570-2581
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouyssegur, J.6
Mazure, N.M.7
-
8
-
-
19944426854
-
Tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors
-
Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT (2005) tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proc Natl Acad Sci USA 102: 407-412
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 407-412
-
-
Berghmans, S.1
Murphey, R.D.2
Wienholds, E.3
Neuberg, D.4
Kutok, J.L.5
Fletcher, C.D.6
Morris, J.P.7
Liu, T.X.8
Schulte-Merker, S.9
Kanki, J.P.10
Plasterk, R.11
Zon, L.I.12
Look, A.T.13
-
9
-
-
0032524285
-
P53 inhibits hypoxia-inducible factor-stimulated transcription
-
Blagosklonny MV, AnWG, Romanova LY, Trepel J, Fojo T, Neckers L (1998) p53 inhibits hypoxia-inducible factor-stimulated transcription. J Biol Chem 273: 11995-11998
-
(1998)
J Biol Chem
, vol.273
, pp. 11995-11998
-
-
Blagosklonny, M.V.1
Anwg Romanova, L.Y.2
Trepel, J.3
Fojo, T.4
Neckers, L.5
-
10
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
Boyd JM, Malstrom S, Subramanian T, Venkatesh LK, Schaeper U, Elangovan B, DoSa-Eipper C, Chinnadurai G (1994) Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79: 341-351
-
(1994)
Cell
, vol.79
, pp. 341-351
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
Venkatesh, L.K.4
Schaeper, U.5
Elangovan, B.6
Dosa-Eipper Chinnadurai C, G.7
-
11
-
-
78650601580
-
Truncated forms of BNIP3 act as dominant negatives inhibiting hypoxia-induced cell death
-
Bristow N, Burton TR, Henson ES, Ong-Justiniano C, Brown M, Gibson SB (2011) Truncated forms of BNIP3 act as dominant negatives inhibiting hypoxia-induced cell death. Biochim Biophys Acta 1812: 302-311
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 302-311
-
-
Bristow, N.1
Burton, T.R.2
Henson, E.S.3
Ong-Justiniano, C.4
Brown, M.5
Gibson, S.B.6
-
12
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
Bruick RK (2000) Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97: 9082-9087
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
13
-
-
62849105988
-
The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death
-
Burton TR, Gibson SB (2009) The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death. Cell Death Differ 16: 515-523
-
(2009)
Cell Death Differ
, vol.16
, pp. 515-523
-
-
Burton, T.R.1
Gibson, S.B.2
-
14
-
-
0038529602
-
Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function
-
Chen D, Li M, Luo J, Gu W (2003) Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function. J Biol Chem 278: 13595-13598
-
(2003)
J Biol Chem
, vol.278
, pp. 13595-13598
-
-
Chen, D.1
Li, M.2
Luo, J.3
Gu, W.4
-
15
-
-
0032932923
-
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
-
Chen G, Cizeau J, Vande Velde C, Park JH, Bozek G, Bolton J, Shi L, Dubik D, Greenberg A (1999) Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J Biol Chem 274: 7-10
-
(1999)
J Biol Chem
, vol.274
, pp. 7-10
-
-
Chen, G.1
Cizeau, J.2
Vande Velde, C.3
Park, J.H.4
Bozek, G.5
Bolton, J.6
Shi, L.7
Dubik, D.8
Greenberg, A.9
-
16
-
-
0031455410
-
The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis
-
Chen G, Ray R, Dubik D, Shi L, Cizeau J, Bleackley RC, Saxena S, Gietz RD, Greenberg AH (1997) The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis. J Exp Med 186: 1975-1983
-
(1997)
J Exp Med
, vol.186
, pp. 1975-1983
-
-
Chen, G.1
Ray, R.2
Dubik, D.3
Shi, L.4
Cizeau, J.5
Bleackley, R.C.6
Saxena, S.7
Gietz, R.D.8
Greenberg, A.H.9
-
17
-
-
68149147330
-
BNIP3 subfamily BH3-only proteins: Mitochondrial stress sensors in normal and pathological functions
-
Chinnadurai G, Vijayalingam S, Gibson SB (2008) BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions. Oncogene 27(Suppl 1): S114-S127
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Chinnadurai, G.1
Vijayalingam, S.2
Gibson, S.B.3
-
18
-
-
0037047692
-
Hypoxia. BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes
-
Crow MT (2002) Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes. Circ Res 91: 183-185
-
(2002)
Circ Res
, vol.91
, pp. 183-185
-
-
Crow, M.T.1
-
19
-
-
0035808387
-
The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression
-
D'Souza S, Xin H, Walter S, Choubey D (2001) The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression. J Biol Chem 276: 298-305
-
(2001)
J Biol Chem
, vol.276
, pp. 298-305
-
-
D'Souza, S.1
Xin, H.2
Walter, S.3
Choubey, D.4
-
20
-
-
3042562282
-
Pivotal role of the cell death factor BNIP3 in ceramideinduced autophagic cell death in malignant glioma cells
-
Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y, Kondo S (2004) Pivotal role of the cell death factor BNIP3 in ceramideinduced autophagic cell death in malignant glioma cells. Cancer Res 64: 4286-4293
-
(2004)
Cancer Res
, vol.64
, pp. 4286-4293
-
-
Daido, S.1
Kanzawa, T.2
Yamamoto, A.3
Takeuchi, H.4
Kondo, Y.5
Kondo, S.6
-
21
-
-
0029861053
-
P202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition
-
Datta B, Li B, Choubey D, Nallur G, Lengyel P (1996) p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition. J Biol Chem 271: 27544-27555
-
(1996)
J Biol Chem
, vol.271
, pp. 27544-27555
-
-
Datta, B.1
Li, B.2
Choubey, D.3
Nallur, G.4
Lengyel, P.5
-
22
-
-
0034632052
-
P53 checkpointdefective cells are sensitive to X rays, but not hypoxia
-
Denko NC, Green SL, Edwards D, Giaccia AJ (2000) p53 checkpointdefective cells are sensitive to X rays, but not hypoxia. Exp Cell Res 258: 82-91
-
(2000)
Exp Cell Res
, vol.258
, pp. 82-91
-
-
Denko, N.C.1
Green, S.L.2
Edwards, D.3
Giaccia, A.J.4
-
23
-
-
34948816749
-
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice
-
Diwan A, Krenz M, Syed FM, Wansapura J, Ren X, Koesters AG, Li H, Kirshenbaum LA, Hahn HS, Robbins J, Jones WK, Dorn GW (2007) Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice. J Clin Invest 117: 2825-2833
-
(2007)
J Clin Invest
, vol.117
, pp. 2825-2833
-
-
Diwan, A.1
Krenz, M.2
Syed, F.M.3
Wansapura, J.4
Ren, X.5
Koesters, A.G.6
Li, H.7
Kirshenbaum, L.A.8
Hahn, H.S.9
Robbins, J.10
Jones, W.K.11
Dorn, G.W.12
-
24
-
-
68149142474
-
Cardiac reanimation: Targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L
-
Dorn II GW, Kirshenbaum LA (2008) Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L. Oncogene 27(Suppl 1): S158-S167
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Dorn, I.I.G.W.1
Kirshenbaum, L.A.2
-
25
-
-
0037115539
-
Tissue-specific induction of p53 targets in vivo
-
Fei P, Bernhard EJ, El-Deiry WS (2002) Tissue-specific induction of p53 targets in vivo. Cancer Res 62: 7316-7327
-
(2002)
Cancer Res
, vol.62
, pp. 7316-7327
-
-
Fei, P.1
Bernhard, E.J.2
El-Deiry, W.S.3
-
26
-
-
19944371176
-
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth
-
Fei P,WangW, Kim SH,Wang S, Burns TF, Sax JK, Buzzai M, Dicker DT, McKenna WG, Bernhard EJ, El-Deiry WS (2004) Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth. Cancer Cell 6: 597-609
-
(2004)
Cancer Cell
, vol.6
, pp. 597-609
-
-
Fei, P.1
Wang, W.2
Kim, S.H.3
Wang, S.4
Burns, T.F.5
Sax, J.K.6
Buzzai, M.7
Dicker, D.T.8
McKenna, W.G.9
Bernhard, E.J.10
El-Deiry, W.S.11
-
27
-
-
33750913134
-
Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3
-
Frazier DP, Wilson A, Graham RM, Thompson JW, Bishopric NH, Webster KA (2006) Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3. Antioxid Redox Signal 8: 1625-1634
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1625-1634
-
-
Frazier, D.P.1
Wilson, A.2
Graham, R.M.3
Thompson, J.W.4
Bishopric, N.H.5
Webster, K.A.6
-
28
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia AJ, Kastan MB (1998) The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 12: 2973-2983
-
(1998)
Genes Dev
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
29
-
-
68149154728
-
BH3-only proteins and their roles in programmed cell death
-
Giam M, Huang DC, Bouillet P (2008) BH3-only proteins and their roles in programmed cell death. Oncogene 27(Suppl 1): S128-S136
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Giam, M.1
Huang, D.C.2
Bouillet, P.3
-
30
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ (1996) Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379: 88-91
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
31
-
-
4644226319
-
A unique pathway of cardiac myocyte death caused by hypoxia-acidosis
-
Graham RM, Frazier DP, Thompson JW, Haliko S, Li H, Wasserlauf BJ, Spiga MG, Bishopric NH, Webster KA (2004) A unique pathway of cardiac myocyte death caused by hypoxia-acidosis. J Exp Biol 207: 3189-3200
-
(2004)
J Exp Biol
, vol.207
, pp. 3189-3200
-
-
Graham, R.M.1
Frazier, D.P.2
Thompson, J.W.3
Haliko, S.4
Li, H.5
Wasserlauf, B.J.6
Spiga, M.G.7
Bishopric, N.H.8
Webster, K.A.9
-
32
-
-
0035030534
-
Hypoxia induces the expression of the pro-apoptotic gene BNIP3
-
Guo K, Searfoss G, Krolikowski D, Pagnoni M, Franks C, Clark K, Yu KT, Jaye M, Ivashchenko Y (2001) Hypoxia induces the expression of the pro-apoptotic gene BNIP3. Cell Death Differ 8: 367-376
-
(2001)
Cell Death Differ
, vol.8
, pp. 367-376
-
-
Guo, K.1
Searfoss, G.2
Krolikowski, D.3
Pagnoni, M.4
Franks, C.5
Clark, K.6
Yu, K.T.7
Jaye, M.8
Ivashchenko, Y.9
-
33
-
-
79953745832
-
Bnip3 as a dual regulator of mitochondrial turnover and cell death in the myocardium
-
Gustafsson AB (2011) Bnip3 as a dual regulator of mitochondrial turnover and cell death in the myocardium. Pediatr Cardiol 32: 267-274
-
(2011)
Pediatr Cardiol
, vol.32
, pp. 267-274
-
-
Gustafsson, A.B.1
-
34
-
-
33845511362
-
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
-
Hamacher-Brady A, Brady NR, Logue SE, Sayen MR, Jinno M, Kirshenbaum LA, Gottlieb RA, Gustafsson AB (2007) Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ 14: 146-157
-
(2007)
Cell Death Differ
, vol.14
, pp. 146-157
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Logue, S.E.3
Sayen, M.R.4
Jinno, M.5
Kirshenbaum, L.A.6
Gottlieb, R.A.7
Gustafsson, A.B.8
-
36
-
-
33749026096
-
Hypoxia-inducible factor-1 and p53: Friends, acquaintances, or strangers?
-
Hammond EM, Giaccia AJ (2006) Hypoxia-inducible factor-1 and p53: friends, acquaintances, or strangers? Clin Cancer Res 12: 5007-5009
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5007-5009
-
-
Hammond, E.M.1
Giaccia, A.J.2
-
37
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and-independent apoptotic pathways
-
Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J, MacLean KH, Han J, Chittenden T, Ihle JN, McKinnon PJ, Cleveland JL, Zambetti GP (2003) Puma is an essential mediator of p53-dependent and-independent apoptotic pathways. Cancer Cell 4: 321-328
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
Yang, C.4
Wang, J.5
Brennan, J.6
MacLean, K.H.7
Han, J.8
Chittenden, T.9
Ihle, J.N.10
McKinnon, P.J.11
Cleveland, J.L.12
Zambetti, G.P.13
-
38
-
-
0030843575
-
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
-
Kim CN, Wang X, Huang Y, Ibrado AM, Liu L, Fang G, Bhalla K (1997a) Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res 57: 3115-3120
-
(1997)
Cancer Res
, vol.57
, pp. 3115-3120
-
-
Kim, C.N.1
Wang, X.2
Huang, Y.3
Ibrado, A.M.4
Liu, L.5
Fang, G.6
Bhalla, K.7
-
39
-
-
0030864485
-
Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
-
Kim CY, Tsai MH, Osmanian C, Graeber TG, Lee JE, Giffard RG, DiPaolo JA, Peehl DM, Giaccia AJ (1997b) Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. Cancer Res 57: 4200-4204
-
(1997)
Cancer Res
, vol.57
, pp. 4200-4204
-
-
Kim, C.Y.1
Tsai, M.H.2
Osmanian, C.3
Graeber, T.G.4
Lee, J.E.5
Giffard, R.G.6
Dipaolo, J.A.7
Peehl, D.M.8
Giaccia, A.J.9
-
40
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
Kothari S, Cizeau J, McMillan-Ward E, Israels SJ, Bailes M, Ens K, Kirshenbaum LA, Gibson SB (2003) BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22: 4734-4744
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
McMillan-Ward, E.3
Israels, S.J.4
Bailes, M.5
Ens, K.6
Kirshenbaum, L.A.7
Gibson, S.B.8
-
41
-
-
0035140981
-
Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation
-
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M, Derr J, Taya Y, Lowe SW, Kastan M, Giaccia A (2001) Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Mol Cell Biol 21: 1297-1310
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1297-1310
-
-
Koumenis, C.1
Alarcon, R.2
Hammond, E.3
Sutphin, P.4
Hoffman, W.5
Murphy, M.6
Derr, J.7
Taya, Y.8
Lowe, S.W.9
Kastan, M.10
Giaccia, A.11
-
43
-
-
57049172037
-
Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion
-
Kubli DA, Quinsay MN, Huang C, Lee Y, Gustafsson AB (2008) Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 295: H2025-H2031
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Kubli, D.A.1
Quinsay, M.N.2
Huang, C.3
Lee, Y.4
Gustafsson, A.B.5
-
44
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88: 323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
45
-
-
67650273017
-
Zebrafish eaf1 and eaf2/u19 mediate effective convergence and extension movements through the maintenance of wnt11 and wnt5 expression
-
Liu JX, Hu B, Wang Y, Gui JF, Xiao W (2009) Zebrafish eaf1 and eaf2/u19 mediate effective convergence and extension movements through the maintenance of wnt11 and wnt5 expression. J Biol Chem 284: 16679-16692
-
(2009)
J Biol Chem
, vol.284
, pp. 16679-16692
-
-
Liu, J.X.1
Hu, B.2
Wang, Y.3
Gui, J.F.4
Xiao, W.5
-
46
-
-
68249106060
-
BH3-only proteins in apoptosis and beyond: An overview
-
Lomonosova E, Chinnadurai G (2008) BH3-only proteins in apoptosis and beyond: an overview. Oncogene 27(Suppl 1): S2-S19
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Lomonosova, E.1
Chinnadurai, G.2
-
47
-
-
77951243028
-
Autophagy regulation by p53
-
Maiuri MC, Galluzzi L, Morselli E, Kepp O, Malik SA, Kroemer G (2010) Autophagy regulation by p53. Curr Opin Cell Biol 22: 181-185
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
48
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, Hurley PJ, Bunz F, Hwang PM (2006) p53 regulates mitochondrial respiration. Science 312: 1650-1653
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
49
-
-
0031929515
-
Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3
-
Matsushima M, Fujiwara T, Takahashi E, Minaguchi T, Eguchi Y, Tsujimoto Y, Suzumori K, Nakamura Y (1998) Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. Genes Chromosomes Cancer 21: 230-235
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 230-235
-
-
Matsushima, M.1
Fujiwara, T.2
Takahashi, E.3
Minaguchi, T.4
Eguchi, Y.5
Tsujimoto, Y.6
Suzumori, K.7
Nakamura, Y.8
-
50
-
-
36148954660
-
The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer
-
Mellor HR, Harris AL (2007) The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer. Cancer Metastasis Rev 26: 553-566
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 553-566
-
-
Mellor, H.R.1
Harris, A.L.2
-
52
-
-
12444252198
-
Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
-
Mirza A,Wu Q,Wang L, McClanahan T, Bishop WR, Gheyas F, Ding W, Hutchins B, Hockenberry T, Kirschmeier P, Greene JR, Liu S (2003) Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression. Oncogene 22: 3645-3654
-
(2003)
Oncogene
, vol.22
, pp. 3645-3654
-
-
Mirza Awu Qwang, L.1
McClanahan, T.2
Bishop, W.R.3
Gheyas, F.4
Ding, W.5
Hutchins, B.6
Hockenberry, T.7
Kirschmeier, P.8
Greene, J.R.9
Liu, S.10
-
53
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
54
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ, George DL (1999) Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 13: 2490-2501
-
(1999)
Genes Dev
, vol.13
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.K.3
Hoffman, W.H.4
Evans, R.M.5
Levine, A.J.6
George, D.L.7
-
55
-
-
0029803281
-
Wild-type p53 negatively regulates the expression of a microtubule-associated protein
-
Murphy M, Hinman A, Levine AJ (1996) Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev 10: 2971-2980
-
(1996)
Genes Dev
, vol.10
, pp. 2971-2980
-
-
Murphy, M.1
Hinman, A.2
Levine, A.J.3
-
56
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K, Vousden KH (2001) PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 7: 683-694
-
(2001)
Mol Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
57
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N (2000a) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
58
-
-
0034664733
-
P53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y (2000b) p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102: 849-862
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
59
-
-
3042779529
-
P53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment
-
Pan Y, Oprysko PR, Asham AM, Koch CJ, Simon MC (2004) p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene 23: 4975-4983
-
(2004)
Oncogene
, vol.23
, pp. 4975-4983
-
-
Pan, Y.1
Oprysko, P.R.2
Asham, A.M.3
Koch, C.J.4
Simon, M.C.5
-
60
-
-
13444258032
-
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
-
Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI (2005) BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol 15: 249-254
-
(2005)
Curr Biol
, vol.15
, pp. 249-254
-
-
Patton, E.E.1
Widlund, H.R.2
Kutok, J.L.3
Kopani, K.R.4
Amatruda, J.F.5
Murphey, R.D.6
Berghmans, S.7
Mayhall, E.A.8
Traver, D.9
Fletcher, C.D.10
Aster, J.C.11
Granter, S.R.12
Look, A.T.13
Lee, C.14
Fisher, D.E.15
Zon, L.I.16
-
61
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10: 1945-1952
-
(1996)
Genes Dev
, vol.10
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.C.3
Kinzler, K.W.4
Vogelstein, B.5
-
62
-
-
36649000935
-
Upregulation of BNIP3 and translocation to mitochondria mediates cyanide-induced apoptosis in cortical cells
-
Prabhakaran K, Li L, Zhang L, Borowitz JL, Isom GE (2007) Upregulation of BNIP3 and translocation to mitochondria mediates cyanide-induced apoptosis in cortical cells. Neuroscience 150: 159-167
-
(2007)
Neuroscience
, vol.150
, pp. 159-167
-
-
Prabhakaran, K.1
Li, L.2
Zhang, L.3
Borowitz, J.L.4
Isom, G.E.5
-
63
-
-
77954957901
-
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
-
Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y (2010) Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature 466: 503-507
-
(2010)
Nature
, vol.466
, pp. 503-507
-
-
Qi, H.H.1
Sarkissian, M.2
Hu, G.Q.3
Wang, Z.4
Bhattacharjee, A.5
Gordon, D.B.6
Gonzales, M.7
Lan, F.8
Ongusaha, P.P.9
Huarte, M.10
Yaghi, N.K.11
Lim, H.12
Garcia, B.A.13
Brizuela, L.14
Zhao, K.15
Roberts, T.M.16
Shi, Y.17
-
64
-
-
0033984094
-
BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites
-
Ray R, Chen G, Vande Velde C, Cizeau J, Park JH, Reed JC, Gietz RD, Greenberg AH (2000) BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites. J Biol Chem 275: 1439-1448
-
(2000)
J Biol Chem
, vol.275
, pp. 1439-1448
-
-
Ray, R.1
Chen, G.2
Vande Velde, C.3
Cizeau, J.4
Park, J.H.5
Reed, J.C.6
Gietz, R.D.7
Greenberg, A.H.8
-
65
-
-
0037047647
-
Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
-
Regula KM, Ens K, Kirshenbaum LA (2002) Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ Res 91: 226-231
-
(2002)
Circ Res
, vol.91
, pp. 226-231
-
-
Regula, K.M.1
Ens, K.2
Kirshenbaum, L.A.3
-
66
-
-
0031593685
-
Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression
-
Roperch JP, Alvaro V, Prieur S, Tuynder M, Nemani M, Lethrosne F, Piouffre L, Gendron MC, Israeli D, Dausset J, Oren M, Amson R, Telerman A (1998) Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression. Nat Med 4: 835-838
-
(1998)
Nat Med
, vol.4
, pp. 835-838
-
-
Roperch, J.P.1
Alvaro, V.2
Prieur, S.3
Tuynder, M.4
Nemani, M.5
Lethrosne, F.6
Piouffre, L.7
Gendron, M.C.8
Israeli, D.9
Dausset, J.10
Oren, M.11
Amson, R.12
Telerman, A.13
-
67
-
-
68349135032
-
Regulation of autophagy through multiple independent hypoxic signaling pathways
-
Rouschop KM, Wouters BG (2009) Regulation of autophagy through multiple independent hypoxic signaling pathways. Curr Mol Med 9: 417-424
-
(2009)
Curr Mol Med
, vol.9
, pp. 417-424
-
-
Rouschop, K.M.1
Wouters, B.G.2
-
68
-
-
0028847563
-
Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein
-
Sabbatini P, Chiou SK, Rao L, White E (1995) Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein. Mol Cell Biol 15: 1060-1070
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1060-1070
-
-
Sabbatini, P.1
Chiou, S.K.2
Rao, L.3
White, E.4
-
69
-
-
32644451972
-
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor
-
Saramaki A, Banwell CM, Campbell MJ, Carlberg C (2006) Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res 34: 543-554
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 543-554
-
-
Saramaki, A.1
Banwell, C.M.2
Campbell, M.J.3
Carlberg, C.4
-
70
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
Sax JK, Fei P, Murphy ME, Bernhard E, Korsmeyer SJ, El-Deiry WS (2002) BID regulation by p53 contributes to chemosensitivity. Nat Cell Biol 4: 842-849
-
(2002)
Nat Cell Biol
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
71
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM (1993) The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75: 495-505
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
72
-
-
2642574174
-
P300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1)
-
Schmid T, Zhou J, Kohl R, Brune B (2004) p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1). Biochem J 380: 289-295
-
(2004)
Biochem J
, vol.380
, pp. 289-295
-
-
Schmid, T.1
Zhou, J.2
Kohl, R.3
Brune, B.4
-
73
-
-
0036527761
-
Dissecting p53 tumor suppressor functions in vivo
-
Schmitt CA, Fridman JS, Yang M, Baranov E, Hoffman RM, Lowe SW (2002) Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 1: 289-298
-
(2002)
Cancer Cell
, vol.1
, pp. 289-298
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Baranov, E.4
Hoffman, R.M.5
Lowe, S.W.6
-
74
-
-
0141818136
-
Integral role of Noxa in p53-mediated apoptotic response
-
Shibue T, Takeda K, Oda E, Tanaka H, Murasawa H, Takaoka A, Morishita Y, Akira S, Taniguchi T, Tanaka N (2003) Integral role of Noxa in p53-mediated apoptotic response. Genes Dev 17: 2233-2238
-
(2003)
Genes Dev
, vol.17
, pp. 2233-2238
-
-
Shibue, T.1
Takeda, K.2
Oda, E.3
Tanaka, H.4
Murasawa, H.5
Takaoka, A.6
Morishita, Y.7
Akira, S.8
Taniguchi, T.9
Tanaka, N.10
-
75
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Mak TW, Lowe SW (1999) Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284: 156-159
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
76
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Opitz-Araya X, McCombie R, Herman JG, Gerald WL, Lazebnik YA, Cordon-Cardo C, Lowe SW (2001) Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409: 207-211
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
Cordon-Cardo, C.11
Lowe, S.W.12
-
77
-
-
1342333155
-
Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; Correlation of BNip3 levels with necrosis and grade
-
Sowter HM, Ferguson M, Pym C, Watson P, Fox SB, Han C, Harris AL (2003) Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade. J Pathol 201: 573-580
-
(2003)
J Pathol
, vol.201
, pp. 573-580
-
-
Sowter, H.M.1
Ferguson, M.2
Pym, C.3
Watson, P.4
Fox, S.B.5
Han, C.6
Harris, A.L.7
-
78
-
-
0035884701
-
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL (2001) HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 61: 6669-6673
-
(2001)
Cancer Res
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
Ratcliffe, P.J.2
Watson, P.3
Greenberg, A.H.4
Harris, A.L.5
-
79
-
-
0033583229
-
Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis
-
Stempien-Otero A, Karsan A, Cornejo CJ, Xiang H, Eunson T, Morrison RS, Kay M, Winn R, Harlan J (1999) Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis. J Biol Chem 274: 8039-8045
-
(1999)
J Biol Chem
, vol.274
, pp. 8039-8045
-
-
Stempien-Otero, A.1
Karsan, A.2
Cornejo, C.J.3
Xiang, H.4
Eunson, T.5
Morrison, R.S.6
Kay, M.7
Winn, R.8
Harlan, J.9
-
80
-
-
0035855668
-
Dephosphorylated hypoxiainducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
-
Suzuki H, Tomida A, Tsuruo T (2001) Dephosphorylated hypoxiainducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene 20: 5779-5788
-
(2001)
Oncogene
, vol.20
, pp. 5779-5788
-
-
Suzuki, H.1
Tomida, A.2
Tsuruo, T.3
-
81
-
-
0028169994
-
P53-dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T, Van Dyke T (1994) p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
Jacks, T.6
Van Dyke, T.7
-
82
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D0Amelio M, Criollo A, Morselli E, Zhu C, Harper F, Nannmark U, Samara C, Pinton P, Vicencio JM, Carnuccio R, Moll UM, Madeo F, Paterlini-Brechot P, Rizzuto R, Szabadkai G et al (2008a) Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10: 676-687
-
(2008)
Nat Cell Biol
, vol.10
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.D.O.5
Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
more..
-
83
-
-
53649084026
-
P53 represses autophagy in a cell cycledependent fashion
-
Tasdemir E, Maiuri MC, Orhon I, Kepp O, Morselli E, Criollo A, Kroemer G (2008b) p53 represses autophagy in a cell cycledependent fashion. Cell Cycle 7: 3006-3011
-
(2008)
Cell Cycle
, vol.7
, pp. 3006-3011
-
-
Tasdemir, E.1
Maiuri, M.C.2
Orhon, I.3
Kepp, O.4
Morselli, E.5
Criollo, A.6
Kroemer, G.7
-
84
-
-
34548235820
-
BNIP3 is an RB/E2F target gene required for hypoxiainduced autophagy
-
Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF (2007) BNIP3 is an RB/E2F target gene required for hypoxiainduced autophagy. Mol Cell Biol 27: 6229-6242
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6229-6242
-
-
Tracy, K.1
Dibling, B.C.2
Spike, B.T.3
Knabb, J.R.4
Schumacker, P.5
MacLeod, K.F.6
-
85
-
-
0033942613
-
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
-
Vande Velde C, Cizeau J, Dubik D, Alimonti J, Brown T, Israels S, Hakem R, Greenberg AH (2000) BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 20: 5454-5468
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5454-5468
-
-
Vande Velde, C.1
Cizeau, J.2
Dubik, D.3
Alimonti, J.4
Brown, T.5
Israels, S.6
Hakem, R.7
Greenberg, A.H.8
-
86
-
-
0032541325
-
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
-
Venot C, Maratrat M, Dureuil C, Conseiller E, Bracco L, Debussche L (1998) The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J 17: 4668-4679
-
(1998)
EMBO J
, vol.17
, pp. 4668-4679
-
-
Venot, C.1
Maratrat, M.2
Dureuil, C.3
Conseiller, E.4
Bracco, L.5
Debussche, L.6
-
87
-
-
0242410719
-
P53-and druginduced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, Adams JM, Strasser A (2003) p53-and druginduced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302: 1036-1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
89
-
-
0035941214
-
Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches
-
Wang L, Wu Q, Qiu P, Mirza A, McGuirk M, Kirschmeier P, Greene JR, Wang Y, Pickett CB, Liu S (2001) Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches. J Biol Chem 276: 43604-43610
-
(2001)
J Biol Chem
, vol.276
, pp. 43604-43610
-
-
Wang, L.1
Wu, Q.2
Qiu, P.3
Mirza, A.4
McGuirk, M.5
Kirschmeier, P.6
Greene, J.R.7
Wang, Y.8
Pickett, C.B.9
Liu, S.10
-
90
-
-
33746350764
-
Heart-targeted overexpression of Nip3a in zebrafish embryos causes abnormal heart development and cardiac dysfunction
-
Wang WD, Huang CJ, Lu YF, Hsin JP, Prabhakar VR, Cheng CF, Hwang SP (2006) Heart-targeted overexpression of Nip3a in zebrafish embryos causes abnormal heart development and cardiac dysfunction. Biochem Biophys Res Commun 347: 979-987
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 979-987
-
-
Wang, W.D.1
Huang, C.J.2
Lu, Y.F.3
Hsin, J.P.4
Prabhakar, V.R.5
Cheng, C.F.6
Hwang, S.P.7
-
92
-
-
33750901803
-
Redox stress and the contributions of BH3-only proteins to infarction
-
Webster KA, Graham RM, Thompson JW, Spiga MG, Frazier DP, Wilson A, Bishopric NH (2006) Redox stress and the contributions of BH3-only proteins to infarction. Antioxid Redox Signal 8: 1667-1676
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1667-1676
-
-
Webster, K.A.1
Graham, R.M.2
Thompson, J.W.3
Spiga, M.G.4
Frazier, D.P.5
Wilson, A.6
Bishopric, N.H.7
-
93
-
-
50349089411
-
Dissecting apoptosis and intrinsic death pathways in the heart
-
Weidman D, Shaw J, Bednarczyk J, Regula KM, Yurkova N, Zhang T, Aguilar F, Kirshenbaum LA (2008) Dissecting apoptosis and intrinsic death pathways in the heart. Methods Enzymol 446: 277-285
-
(2008)
Methods Enzymol
, vol.446
, pp. 277-285
-
-
Weidman, D.1
Shaw, J.2
Bednarczyk, J.3
Regula, K.M.4
Yurkova, N.5
Zhang, T.6
Aguilar, F.7
Kirshenbaum, L.A.8
-
94
-
-
33745123281
-
Upregulation of BNIP3 promotes apoptosis of lung cancer cells that were induced by p53
-
Yan J, Yun H, Yang Y, Jing B, Feng C, Song-bin F (2006) Upregulation of BNIP3 promotes apoptosis of lung cancer cells that were induced by p53. Biochem Biophys Res Commun 346: 501-507
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 501-507
-
-
Yan, J.1
Yun, H.2
Yang, Y.3
Jing, B.4
Feng, C.5
Song-Bin, F.6
-
95
-
-
0032524656
-
Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence
-
Yasuda M, Theodorakis P, Subramanian T, Chinnadurai G (1998) Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J Biol Chem 273: 12415-12421
-
(1998)
J Biol Chem
, vol.273
, pp. 12415-12421
-
-
Yasuda, M.1
Theodorakis, P.2
Subramanian, T.3
Chinnadurai, G.4
-
96
-
-
0037452759
-
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
-
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L (2003) PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci USA 100: 1931-1936
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1931-1936
-
-
Yu, J.1
Wang, Z.2
Kinzler, K.W.3
Vogelstein, B.4
Zhang, L.5
-
97
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283: 10892-10903
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
98
-
-
67549101188
-
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
-
Zhang J, Ney PA (2009) Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ 16: 939-946
-
(2009)
Cell Death Differ
, vol.16
, pp. 939-946
-
-
Zhang, J.1
Ney, P.A.2
-
99
-
-
0034704151
-
Definition of the p53 functional domains necessary for inducing apoptosis
-
Zhu J, Zhang S, Jiang J, Chen X (2000) Definition of the p53 functional domains necessary for inducing apoptosis. J Biol Chem 275: 39927-39934
-
(2000)
J Biol Chem
, vol.275
, pp. 39927-39934
-
-
Zhu, J.1
Zhang, S.2
Jiang, J.3
Chen, X.4
-
100
-
-
0032557649
-
Identification of a novel p53 functional domain that is necessary for mediating apoptosis
-
Zhu J, Zhou W, Jiang J, Chen X (1998) Identification of a novel p53 functional domain that is necessary for mediating apoptosis. J Biol Chem 273: 13030-13036
-
(1998)
J Biol Chem
, vol.273
, pp. 13030-13036
-
-
Zhu, J.1
Zhou, W.2
Jiang, J.3
Chen, X.4
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