메뉴 건너뛰기




Volumn 117, Issue 10, 2007, Pages 2825-2833

Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BNIP3;

EID: 34948816749     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI32490     Document Type: Article
Times cited : (264)

References (78)
  • 1
    • 0035975980 scopus 로고    scopus 로고
    • Sudden cardiac death in the United States, 1989 to 1998
    • Zheng, Z.J., Croft, J.B., Giles, W.H., and Mensah, G.A. 2001. Sudden cardiac death in the United States, 1989 to 1998. Circulation. 104:2158-2163.
    • (2001) Circulation , vol.104 , pp. 2158-2163
    • Zheng, Z.J.1    Croft, J.B.2    Giles, W.H.3    Mensah, G.A.4
  • 2
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Thom, T., et al. 2006. Heart disease and stroke statistics - 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 113:e85-e151.
    • (2006) Circulation , vol.113
    • Thom, T.1
  • 3
    • 7044220933 scopus 로고    scopus 로고
    • NRMI and current treatment patterns for ST-elevation myocardial infarction
    • Gibson, C.M. 2004. NRMI and current treatment patterns for ST-elevation myocardial infarction. Am. Heart J. 148:S29-S33.
    • (2004) Am. Heart J , vol.148
    • Gibson, C.M.1
  • 4
    • 9044239676 scopus 로고
    • A clinical trial of the angiotensin-converting- enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group
    • Kober, L., et al. 1995. A clinical trial of the angiotensin-converting- enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group. N. Engl. J. Med. 333:1670-1676.
    • (1995) N. Engl. J. Med , vol.333 , pp. 1670-1676
    • Kober, L.1
  • 5
    • 3843091541 scopus 로고    scopus 로고
    • ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction - executive summary: A report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)
    • Antman, E.M., et al. 2004. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction - executive summary: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction). Circulation. 110:588-636.
    • (2004) Circulation , vol.110 , pp. 588-636
    • Antman, E.M.1
  • 6
    • 0025266820 scopus 로고
    • Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications
    • Pfeffer, M.A., and Braunwald, E. 1990. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation. 81:1161-1172.
    • (1990) Circulation , vol.81 , pp. 1161-1172
    • Pfeffer, M.A.1    Braunwald, E.2
  • 7
    • 0037130780 scopus 로고    scopus 로고
    • Non-ischemic infarct extension: A new type of infarct enlargement and a potential therapeutic target
    • Ratcliffe, M.B. 2002. Non-ischemic infarct extension: A new type of infarct enlargement and a potential therapeutic target. J. Am. Coll. Cardiol. 40:1168-1171.
    • (2002) J. Am. Coll. Cardiol , vol.40 , pp. 1168-1171
    • Ratcliffe, M.B.1
  • 8
    • 0035980171 scopus 로고    scopus 로고
    • Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes
    • Pimentel, D.R., et al. 2001. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ. Res. 89:453-460.
    • (2001) Circ. Res , vol.89 , pp. 453-460
    • Pimentel, D.R.1
  • 9
    • 0037130746 scopus 로고    scopus 로고
    • Extension of borderzone myocardium in postinfarction dilated cardiomyopathy
    • Jackson, B.M., et al. 2002. Extension of borderzone myocardium in postinfarction dilated cardiomyopathy. J. Am. Coll. Cardiol. 40:1160-1167.
    • (2002) J. Am. Coll. Cardiol , vol.40 , pp. 1160-1167
    • Jackson, B.M.1
  • 10
    • 0033547781 scopus 로고    scopus 로고
    • Restraining infarct expansion preserves left ventricular geometry and function after acute anteroapical infarction
    • Kelley, S.T., et al. 1999. Restraining infarct expansion preserves left ventricular geometry and function after acute anteroapical infarction. Circulation. 99:135-142.
    • (1999) Circulation , vol.99 , pp. 135-142
    • Kelley, S.T.1
  • 11
    • 24644459317 scopus 로고    scopus 로고
    • Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction
    • Blom, A.S., et al. 2005. Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction. Circulation. 112:1274-1283.
    • (2005) Circulation , vol.112 , pp. 1274-1283
    • Blom, A.S.1
  • 12
    • 0030766192 scopus 로고    scopus 로고
    • Apoptosis in the failing human heart
    • Olivetti, G., et al. 1997. Apoptosis in the failing human heart. N. Engl. J. Med. 336:1131-1141.
    • (1997) N. Engl. J. Med , vol.336 , pp. 1131-1141
    • Olivetti, G.1
  • 13
    • 0031023852 scopus 로고    scopus 로고
    • Apoptosis in human acute myocardial infarction
    • Saraste, A., et al. 1997. Apoptosis in human acute myocardial infarction. Circulation. 95:320-323.
    • (1997) Circulation , vol.95 , pp. 320-323
    • Saraste, A.1
  • 14
    • 0038796894 scopus 로고    scopus 로고
    • Region- and type-specific induction of matrix metalloproteinases in postmyocardial infarction remodeling
    • Wilson, E.M., et al. 2003. Region- and type-specific induction of matrix metalloproteinases in postmyocardial infarction remodeling. Circulation. 107:2857-2863.
    • (2003) Circulation , vol.107 , pp. 2857-2863
    • Wilson, E.M.1
  • 15
    • 0027521065 scopus 로고
    • Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine/paracrine mechanism
    • Sadoshima, J., and Izumo, S. 1993. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J. 12:1681-1692.
    • (1993) EMBO J , vol.12 , pp. 1681-1692
    • Sadoshima, J.1    Izumo, S.2
  • 16
    • 24744436182 scopus 로고    scopus 로고
    • Physiologic growth and pathologic genes in cardiac development and cardiomyopathy
    • Dorn, G.W. 2005. Physiologic growth and pathologic genes in cardiac development and cardiomyopathy. Trends Cardiovasc. Med. 15:185-189.
    • (2005) Trends Cardiovasc. Med , vol.15 , pp. 185-189
    • Dorn, G.W.1
  • 17
    • 14644414790 scopus 로고    scopus 로고
    • Protein kinase cascades in the regulation of cardiac hypertrophy
    • doi:10.1172/JCI200524178
    • Dorn, G.W., and Force, T. 2005. Protein kinase cascades in the regulation of cardiac hypertrophy. J. Clin. Invest. 115:527-537. doi:10.1172/JCI200524178.
    • (2005) J. Clin. Invest , vol.115 , pp. 527-537
    • Dorn, G.W.1    Force, T.2
  • 18
    • 0032570292 scopus 로고    scopus 로고
    • Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor
    • Yaoita, H., Ogawa, K., Maehara, K., and Maruyama, Y. 1998. Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor. Circulation. 97:276-281.
    • (1998) Circulation , vol.97 , pp. 276-281
    • Yaoita, H.1    Ogawa, K.2    Maehara, K.3    Maruyama, Y.4
  • 19
    • 1042299088 scopus 로고    scopus 로고
    • Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction
    • Chandrashekhar, Y., Sen, S., Anway, R., Shuros, A., and Anand, I. 2004. Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction. J. Am. Coll. Cardiol. 43:295-301.
    • (2004) J. Am. Coll. Cardiol , vol.43 , pp. 295-301
    • Chandrashekhar, Y.1    Sen, S.2    Anway, R.3    Shuros, A.4    Anand, I.5
  • 20
    • 0028113218 scopus 로고
    • Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
    • Boyd, J.M., et al. 1994. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell. 79:341-351.
    • (1994) Cell , vol.79 , pp. 341-351
    • Boyd, J.M.1
  • 21
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
    • Bruick, R.K. 2000. Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc. Natl. Acad. Sci. U. S. A. 97:9082-9087.
    • (2000) Proc. Natl. Acad. Sci. U. S. A , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 22
    • 33644973657 scopus 로고    scopus 로고
    • Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress
    • Galvez, A.S., et al. 2006. Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress. J. Biol. Chem. 281:1442-1448.
    • (2006) J. Biol. Chem , vol.281 , pp. 1442-1448
    • Galvez, A.S.1
  • 23
    • 0037047647 scopus 로고    scopus 로고
    • Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes
    • Regula, K.M., Ens, K., and Kirshenbaum, L.A. 2002. Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes. Circ. Res. 91:226-231.
    • (2002) Circ. Res , vol.91 , pp. 226-231
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 24
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter, H.M., Ratcliffe, P.J., Watson, P., Greenberg, A.H., and Harris, A.L. 2001. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 61:6669-6673.
    • (2001) Cancer Res , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 25
    • 33845511362 scopus 로고    scopus 로고
    • Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
    • Hamacher-Brady, A., et al. 2007. Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ. 14:146-157.
    • (2007) Cell Death Differ , vol.14 , pp. 146-157
    • Hamacher-Brady, A.1
  • 26
    • 0036789917 scopus 로고    scopus 로고
    • Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
    • Kubasiak, L.A., Hernandez, O.M., Bishopric, N.H., and Webster, K.A. 2002. Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc. Natl. Acad. Sci. U. S. A. 99:12825-12830.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 12825-12830
    • Kubasiak, L.A.1    Hernandez, O.M.2    Bishopric, N.H.3    Webster, K.A.4
  • 27
    • 0032524656 scopus 로고    scopus 로고
    • Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence
    • Yasuda, M., Theodorakis, P., Subramanian, T., and Chinnadurai, G. 1998. Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J. Biol. Chem. 273:12415-12421.
    • (1998) J. Biol. Chem , vol.273 , pp. 12415-12421
    • Yasuda, M.1    Theodorakis, P.2    Subramanian, T.3    Chinnadurai, G.4
  • 28
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet, P., et al. 1999. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 286:1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1
  • 29
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
    • Bouillet, P., et al. 2002. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature. 415:922-926.
    • (2002) Nature , vol.415 , pp. 922-926
    • Bouillet, P.1
  • 30
    • 0042424706 scopus 로고    scopus 로고
    • Bad-deficient mice develop diffuse large B cell lymphoma
    • Ranger, A.M., et al. 2003. Bad-deficient mice develop diffuse large B cell lymphoma. Proc. Natl. Acad. Sci. U. S. A. 100:9324-9329.
    • (2003) Proc. Natl. Acad. Sci. U. S. A , vol.100 , pp. 9324-9329
    • Ranger, A.M.1
  • 31
    • 34249852766 scopus 로고    scopus 로고
    • -/- mice reveals a mechanism for apoptotic modulation of erythropoiesis
    • -/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc. Natl. Acad. Sci. U. S. A. 104:6794-6799.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.104 , pp. 6794-6799
    • Diwan, A.1
  • 32
    • 0024573890 scopus 로고
    • Limitation of myocardial reperfusion injury by intravenous perfluorochemicals. Role of neutrophil activation
    • Bajaj, A.K., et al. 1989. Limitation of myocardial reperfusion injury by intravenous perfluorochemicals. Role of neutrophil activation. Circulation. 79:645-656.
    • (1989) Circulation , vol.79 , pp. 645-656
    • Bajaj, A.K.1
  • 33
    • 0025944661 scopus 로고
    • Inflammation in the course of early myocardial ischemia
    • Entman, M.L., et al. 1991. Inflammation in the course of early myocardial ischemia. FASEB J. 5:2529-2537.
    • (1991) FASEB J , vol.5 , pp. 2529-2537
    • Entman, M.L.1
  • 34
    • 34948825993 scopus 로고    scopus 로고
    • A murine model for studying hematopoiesis and immunity in heart failure
    • Iversen, P.O., and Sorensen, D.R. 2007. A murine model for studying hematopoiesis and immunity in heart failure. Methods Mol. Biol. 360:269-275.
    • (2007) Methods Mol. Biol , vol.360 , pp. 269-275
    • Iversen, P.O.1    Sorensen, D.R.2
  • 35
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • van Amerongen, M.J., Harmsen, M.C., van Rooijen, N., Petersen, A.H., and van Luyn, M.J. 2007. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am. J. Pathol. 170:818-829.
    • (2007) Am. J. Pathol , vol.170 , pp. 818-829
    • van Amerongen, M.J.1    Harmsen, M.C.2    van Rooijen, N.3    Petersen, A.H.4    van Luyn, M.J.5
  • 36
    • 0027458580 scopus 로고
    • Histology after stenting of human saphenous vein bypass grafts: Observations from surgically excised grafts 3 to 320 days after stent implantation
    • van Beusekom, H.M., et al. 1993. Histology after stenting of human saphenous vein bypass grafts: observations from surgically excised grafts 3 to 320 days after stent implantation. J. Am. Coll. Cardiol. 21:45-54.
    • (1993) J. Am. Coll. Cardiol , vol.21 , pp. 45-54
    • van Beusekom, H.M.1
  • 37
    • 2542498813 scopus 로고    scopus 로고
    • Infarct resorption, compensatory hypertrophy, and differing patterns of ventricular remodeling following myocardial infarctions of varying size
    • Fieno, D.S., et al. 2004. Infarct resorption, compensatory hypertrophy, and differing patterns of ventricular remodeling following myocardial infarctions of varying size. J. Am. Coll. Cardiol. 43:2124-2131.
    • (2004) J. Am. Coll. Cardiol , vol.43 , pp. 2124-2131
    • Fieno, D.S.1
  • 38
    • 33747183723 scopus 로고    scopus 로고
    • Passive ventricular constraint prevents transmural shear strain progression in left ventricle remodeling
    • Cheng, A., et al. 2006. Passive ventricular constraint prevents transmural shear strain progression in left ventricle remodeling. Circulation. 114:I79-I86.
    • (2006) Circulation , vol.114
    • Cheng, A.1
  • 39
    • 0033862037 scopus 로고    scopus 로고
    • Progressive left ventricular remodeling and apoptosis late after myocardial infarction in mouse heart
    • Sam, F., et al. 2000. Progressive left ventricular remodeling and apoptosis late after myocardial infarction in mouse heart. Am. J. Physiol. Heart Circ. Physiol 279:H422-H428.
    • (2000) Am. J. Physiol. Heart Circ. Physiol , vol.279
    • Sam, F.1
  • 40
    • 0034979621 scopus 로고    scopus 로고
    • Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats
    • Palojoki, E., et al. 2001. Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats. Am. J. Physiol. Heart Circ. Physiol. 280:H2726-H2731.
    • (2001) Am. J. Physiol. Heart Circ. Physiol , vol.280
    • Palojoki, E.1
  • 41
    • 0035030534 scopus 로고    scopus 로고
    • Hypoxia induces the expression of the pro-apoptotic gene BNIP3
    • Guo, K., et al. 2001. Hypoxia induces the expression of the pro-apoptotic gene BNIP3. Cell Death Differ. 8:367-376.
    • (2001) Cell Death Differ , vol.8 , pp. 367-376
    • Guo, K.1
  • 42
    • 33847217304 scopus 로고    scopus 로고
    • Evidence of oxidative stress-induced BNIP3 expression in amyloid beta neurotoxicity
    • Zhang, S., et al. 2007. Evidence of oxidative stress-induced BNIP3 expression in amyloid beta neurotoxicity. Brain Res. 1138:221-230.
    • (2007) Brain Res , vol.1138 , pp. 221-230
    • Zhang, S.1
  • 43
    • 33745102696 scopus 로고    scopus 로고
    • Hypoxia and expression of the proapoptotic regulator BNIP3 in cervical cancer
    • Leo, C., Horn, L.C., and Hockel, M. 2006. Hypoxia and expression of the proapoptotic regulator BNIP3 in cervical cancer. Int. J. Gynecol.Cancer. 16:1314-1320.
    • (2006) Int. J. Gynecol.Cancer , vol.16 , pp. 1314-1320
    • Leo, C.1    Horn, L.C.2    Hockel, M.3
  • 44
    • 20344388514 scopus 로고    scopus 로고
    • Proapoptotic effects of caspase-1/interleukin- converting enzyme dominate in myocardial ischemia
    • Syed, F.M., et al. 2005. Proapoptotic effects of caspase-1/interleukin- converting enzyme dominate in myocardial ischemia. Circ. Res. 96:1103-1109.
    • (2005) Circ. Res , vol.96 , pp. 1103-1109
    • Syed, F.M.1
  • 45
    • 0036061644 scopus 로고    scopus 로고
    • Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy
    • Yussman, M.G., et al. 2002. Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy. Nat. Med. 8:725-730.
    • (2002) Nat. Med , vol.8 , pp. 725-730
    • Yussman, M.G.1
  • 46
    • 34247121951 scopus 로고    scopus 로고
    • Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis
    • Galvez, A.S., et al. 2007. Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis. Circ. Res. 100:1071-1078.
    • (2007) Circ. Res , vol.100 , pp. 1071-1078
    • Galvez, A.S.1
  • 47
    • 85047694494 scopus 로고    scopus 로고
    • A mechanistic role for cardiac myocyte apoptosis in heart failure
    • doi:10.1172/JCI200317664
    • Wencker, D., et al. 2003. A mechanistic role for cardiac myocyte apoptosis in heart failure. J. Clin. Invest. 111:1497-1504. doi:10.1172/JCI200317664.
    • (2003) J. Clin. Invest , vol.111 , pp. 1497-1504
    • Wencker, D.1
  • 48
    • 23844468503 scopus 로고    scopus 로고
    • Role of apoptosis in ventricular remodeling
    • Chandrashekhar, Y. 2005. Role of apoptosis in ventricular remodeling. Curr. Heart Fail. Rep. 2:18-22.
    • (2005) Curr. Heart Fail. Rep , vol.2 , pp. 18-22
    • Chandrashekhar, Y.1
  • 49
    • 0037089068 scopus 로고    scopus 로고
    • BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
    • Bouillet, P., and Strasser, A. 2002. BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J. Cell Sci. 115:1567-1574.
    • (2002) J. Cell Sci , vol.115 , pp. 1567-1574
    • Bouillet, P.1    Strasser, A.2
  • 50
    • 34547471625 scopus 로고    scopus 로고
    • Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak
    • Kubli, D.A., Ycaza, J.E., and Gustafsson, A.B. 2007. Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak. Biochem. J. 405:407-415.
    • (2007) Biochem. J , vol.405 , pp. 407-415
    • Kubli, D.A.1    Ycaza, J.E.2    Gustafsson, A.B.3
  • 51
    • 0031455410 scopus 로고    scopus 로고
    • The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis
    • Chen, G., et al. 1997. The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis. J. Exp. Med. 186:1975-1983.
    • (1997) J. Exp. Med , vol.186 , pp. 1975-1983
    • Chen, G.1
  • 52
    • 0032932923 scopus 로고    scopus 로고
    • Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
    • Chen, G., et al. 1999. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J. Biol. Chem. 274:7-10.
    • (1999) J. Biol. Chem , vol.274 , pp. 7-10
    • Chen, G.1
  • 53
    • 4644226319 scopus 로고    scopus 로고
    • A unique pathway of cardiac myocyte death caused by hypoxia-acidosis
    • Graham, R.M., et al. 2004. A unique pathway of cardiac myocyte death caused by hypoxia-acidosis. J. Exp. Biol. 207:3189-3200.
    • (2004) J. Exp. Biol , vol.207 , pp. 3189-3200
    • Graham, R.M.1
  • 54
    • 0033942613 scopus 로고    scopus 로고
    • BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
    • Vande, V.C., et al. 2000. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol. Cell. Biol. 20:5454-5468.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 5454-5468
    • Vande, V.C.1
  • 56
    • 0029956792 scopus 로고    scopus 로고
    • Apoptosis in ischemic and reperfused rat myocardium
    • Fliss, H., and Gattinger, D. 1996. Apoptosis in ischemic and reperfused rat myocardium. Circ. Res. 79:949-956.
    • (1996) Circ. Res , vol.79 , pp. 949-956
    • Fliss, H.1    Gattinger, D.2
  • 58
    • 0034702911 scopus 로고    scopus 로고
    • Involvement of CD95/ Apo1/Fas in cell death after myocardial ischemia
    • Jeremias, I., et al. 2000. Involvement of CD95/ Apo1/Fas in cell death after myocardial ischemia. Circulation. 102:915-920.
    • (2000) Circulation , vol.102 , pp. 915-920
    • Jeremias, I.1
  • 59
    • 0037304773 scopus 로고    scopus 로고
    • Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
    • Lee, P., et al. 2003. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. Am. J. Physiol. Heart Circ. Physiol. 284:H456-H463.
    • (2003) Am. J. Physiol. Heart Circ. Physiol , vol.284
    • Lee, P.1
  • 60
    • 0034280579 scopus 로고    scopus 로고
    • Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways
    • Yin, X.M. 2000. Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways. Cell Res. 10:161-167.
    • (2000) Cell Res , vol.10 , pp. 161-167
    • Yin, X.M.1
  • 61
    • 14644413468 scopus 로고    scopus 로고
    • Death begets failure in the heart
    • doi:10.1172/JCI200524569
    • Foo, R.S.-Y, Mani, K., and Kitsis, R.N. 2005. Death begets failure in the heart. J. Clin. Invest. 115:565-571. doi:10.1172/JCI200524569.
    • (2005) J. Clin. Invest , vol.115 , pp. 565-571
    • Foo, R.S.-Y.1    Mani, K.2    Kitsis, R.N.3
  • 62
    • 33644874937 scopus 로고    scopus 로고
    • Nuclear factor-kappaB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes
    • Baetz, D., et al. 2005. Nuclear factor-kappaB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes. Circulation. 112:3777-3785.
    • (2005) Circulation , vol.112 , pp. 3777-3785
    • Baetz, D.1
  • 63
    • 0010034895 scopus 로고    scopus 로고
    • Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury
    • Brocheriou, V., et al. 2000. Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury. J. Gene Med. 2:326-333.
    • (2000) J. Gene Med , vol.2 , pp. 326-333
    • Brocheriou, V.1
  • 64
    • 0008996894 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice
    • Chen, Z., Chua, C.C., Ho, Y.S., Hamdy, R.C., and Chua, B.H. 2001. Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice. Am. J. Physiol. Heart Circ. Physiol. 280:H2313-H2320.
    • (2001) Am. J. Physiol. Heart Circ. Physiol , vol.280
    • Chen, Z.1    Chua, C.C.2    Ho, Y.S.3    Hamdy, R.C.4    Chua, B.H.5
  • 65
    • 0034162004 scopus 로고    scopus 로고
    • Cardiac remodeling - concepts and clinical implications: A consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling
    • Cohn, J.N., Ferrari, R., and Sharpe, N. 2000. Cardiac remodeling - concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J. Am. Coll. Cardiol. 35:569-582.
    • (2000) J. Am. Coll. Cardiol , vol.35 , pp. 569-582
    • Cohn, J.N.1    Ferrari, R.2    Sharpe, N.3
  • 66
    • 24944494805 scopus 로고    scopus 로고
    • Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy
    • Yu, C.M., et al. 2005. Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy. Circulation. 112:1580-1586.
    • (2005) Circulation , vol.112 , pp. 1580-1586
    • Yu, C.M.1
  • 67
    • 0037046189 scopus 로고    scopus 로고
    • Rebuilding a damaged heart: Long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function
    • Muller-Ehmsen, J., et al. 2002. Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function. Circulation. 105:1720-1726.
    • (2002) Circulation , vol.105 , pp. 1720-1726
    • Muller-Ehmsen, J.1
  • 68
    • 33847609314 scopus 로고    scopus 로고
    • Concise review: Stem cells, myocardial regeneration, and methodological artifacts
    • Anversa, P., et al. 2007. Concise review: stem cells, myocardial regeneration, and methodological artifacts. Stem Cells. 25:589-601.
    • (2007) Stem Cells , vol.25 , pp. 589-601
    • Anversa, P.1
  • 69
    • 24344463873 scopus 로고    scopus 로고
    • Murine echocardiography: A practical approach for phenotyping genetically manipulated and surgically modeled mice
    • Syed, F., Diwan, A., and Hahn, H.S. 2005. Murine echocardiography: a practical approach for phenotyping genetically manipulated and surgically modeled mice. J. Am. Soc. Echocardiogr. 18:982-990.
    • (2005) J. Am. Soc. Echocardiogr , vol.18 , pp. 982-990
    • Syed, F.1    Diwan, A.2    Hahn, H.S.3
  • 70
    • 10644269378 scopus 로고    scopus 로고
    • Physiological growth synergizes with pathological genes in experimental cardiomyopathy
    • Syed, F., et al. 2004. Physiological growth synergizes with pathological genes in experimental cardiomyopathy. Circ. Res. 95:1200-1206.
    • (2004) Circ. Res , vol.95 , pp. 1200-1206
    • Syed, F.1
  • 71
    • 0031782261 scopus 로고    scopus 로고
    • Demonstration of an early and a late phase of ischemic preconditioning in mice
    • Guo, Y., et al. 1998. Demonstration of an early and a late phase of ischemic preconditioning in mice. Am. J. Physiol. 275:H1375-H1387.
    • (1998) Am. J. Physiol , vol.275
    • Guo, Y.1
  • 72
    • 4143085297 scopus 로고    scopus 로고
    • TNF-alpha is required for late ischemic preconditioning but not for remote preconditioning of trauma
    • Ren, X., Wang, Y., and Jones, W.K. 2004. TNF-alpha is required for late ischemic preconditioning but not for remote preconditioning of trauma. J. Surg. Res. 121:120-129.
    • (2004) J. Surg. Res , vol.121 , pp. 120-129
    • Ren, X.1    Wang, Y.2    Jones, W.K.3
  • 73
    • 1542514708 scopus 로고    scopus 로고
    • Simultaneous evaluation of infarct size and cardiac function in intact mice by contrast-enhanced cardiac magnetic resonance imaging reveals contractile dysfunction in noninfarcted regions early after myocardial infarction
    • Yang, Z., Berr, S.S., Gilson, W.D., Toufektsian, M.C., and French, B.A. 2004. Simultaneous evaluation of infarct size and cardiac function in intact mice by contrast-enhanced cardiac magnetic resonance imaging reveals contractile dysfunction in noninfarcted regions early after myocardial infarction. Circulation. 109:1161-1167.
    • (2004) Circulation , vol.109 , pp. 1161-1167
    • Yang, Z.1    Berr, S.S.2    Gilson, W.D.3    Toufektsian, M.C.4    French, B.A.5
  • 74
    • 0037372879 scopus 로고    scopus 로고
    • Stunned, infarcted, and normal myocardium in dogs: Simultaneous differentiation by using gadolinium-enhanced cine MR imaging with magnetization transfer contrast
    • Weiss, C.R., et al. 2003. Stunned, infarcted, and normal myocardium in dogs: simultaneous differentiation by using gadolinium-enhanced cine MR imaging with magnetization transfer contrast. Radiology. 226:723-730.
    • (2003) Radiology , vol.226 , pp. 723-730
    • Weiss, C.R.1
  • 75
    • 0037373406 scopus 로고    scopus 로고
    • MR imaging of reperfused myocardial infarction: Comparison of necrosis-specific and intravascular contrast agents in a cat model
    • Lee, S.S., et al. 2003. MR imaging of reperfused myocardial infarction: comparison of necrosis-specific and intravascular contrast agents in a cat model. Radiology. 226:739-747.
    • (2003) Radiology , vol.226 , pp. 739-747
    • Lee, S.S.1
  • 76
    • 0037123140 scopus 로고    scopus 로고
    • Imaging of myocardial infarction: Comparison of magnevist and gadophrin-3 in rabbits
    • Barkhausen, J., Ebert, W., Debatin, J.F., and Weinmann, H.J. 2002. Imaging of myocardial infarction: comparison of magnevist and gadophrin-3 in rabbits. J. Am. Coll. Cardiol. 39:1392-1398.
    • (2002) J. Am. Coll. Cardiol , vol.39 , pp. 1392-1398
    • Barkhausen, J.1    Ebert, W.2    Debatin, J.F.3    Weinmann, H.J.4
  • 77
    • 0022512665 scopus 로고
    • Early myocardial infarction. A feasible histologic diagnostic procedure
    • Milei, J., and Storino, R. 1986. Early myocardial infarction. A feasible histologic diagnostic procedure. Jpn. Heart J. 27:307-319.
    • (1986) Jpn. Heart J , vol.27 , pp. 307-319
    • Milei, J.1    Storino, R.2
  • 78
    • 0037418939 scopus 로고    scopus 로고
    • Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter
    • Sanbe, A., et al. 2003. Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter. Circ. Res. 92:609-616.
    • (2003) Circ. Res , vol.92 , pp. 609-616
    • Sanbe, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.