p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1)

Biochemical Journal

Volumn 380, Issue 1, 2004, Pages 289-295

  Schmid, Tobias ^a   Zhou, Jie ^a   Köhl, Roman ^a   Brüne, Bernhard ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Hypoxia; Hypoxia inducible factor 1 (HIF 1 ); p300; p53; Protein degradation; Transcriptional regulation

Indexed keywords

BIODEGRADATION; METABOLISM; PROTEINS; TUMORS;

TRANSCRIPTIONAL REPRESSIONS; TUMOR SUPPRESSORS;

BIOCHEMISTRY;

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P300; PROTEIN P53; VON HIPPEL LINDAU PROTEIN;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TRANSACTIVATION;

BINDING SITES; BINDING, COMPETITIVE; CARCINOMA; CARCINOMA, RENAL CELL; CELL HYPOXIA; CELL LINE, TUMOR; COLONIC NEOPLASMS; GENES, P53; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY NEOPLASMS; LUCIFERASES; MACROMOLECULAR SUBSTANCES; NUCLEAR PROTEINS; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 2642574174     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031299     Document Type: Article

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