p53 Mutants have selective dominant-negative effects on apoptosis but not growth arrest in human cancer cell lines

Molecular and Cellular Biology

Volumn 20, Issue 3, 2000, Pages 770-778

  Aurelio, Oscar N ^a,b   Kong, Xiao Tang ^a   Gupta, Swati ^a   Stanbridge, Eric J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN BAX; PROTEIN P21; PROTEIN P53; RNA;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOMINANT GENE; EXPRESSION VECTOR; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; LUNG CARCINOMA; MISSENSE MUTATION; NICK END LABELING; OSTEOSARCOMA CELL; PRIORITY JOURNAL; RECESSIVE GENE; TRANSACTIVATION; TRANSCRIPTION REGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BONE NEOPLASMS; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENZYME INHIBITORS; GENES, P53; HUMANS; LUNG NEOPLASMS; OSTEOSARCOMA; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033965487     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.3.770-778.2000     Document Type: Article

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