p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment

Oncogene

Volumn 23, Issue 29, 2004, Pages 4975-4983

  Pan, Yi ^a,b   Oprysko, Patricia R ^c   Asham, Andrew M ^a,b   Koch, Cameron J ^c   Simon, Marie Celeste ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anoxia; HIF; Hypoxia; p53; Tumor cells

Indexed keywords

COBALT CHLORIDE; DEFEROXAMINE MESYLATE; PROTEIN DERIVATIVE; PROTEIN P53; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; TRANSCRIPTION FACTOR;

ACIDOSIS; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; GENE TRANSLOCATION; HYPOXIA; MICROENVIRONMENT; MOUSE; NONHUMAN; NUTRIENT AVAILABILITY; OXYGEN CONCENTRATION; PASTEURIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN STABILITY; APOPTOSIS; CELL CULTURE; CELL HYPOXIA; CELL NUCLEUS; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

ANIMALIA;

APOPTOSIS; CELL HYPOXIA; CELL NUCLEUS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OXYGEN; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 3042779529     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207657     Document Type: Article

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