Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes

Diabetologia

Volumn 54, Issue 8, 2011, Pages 1946-1956

  Bento, C F ^a   Pereira, P ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Carboxy terminus of HSP70 interacting protein; Diabetes; Hyperglycaemia; Hypoxia; Hypoxia inducible factor 1; Methylglyoxal; Neovascularisation; Review; VEGF; von Hippel Lindau protein

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CHEMOKINE RECEPTOR CXCR4; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; GLUTATHIONE SYNTHASE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HISTONE ACETYLTRANSFERASE PCAF; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN TYROSINE KINASE; RECEPTOR FOR ACTIVATED C KINASE 1; STROMAL CELL DERIVED FACTOR 1; SUMO PROTEIN; TRICARBOXYLIC ACID; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VON HIPPEL LINDAU PROTEIN;

DIABETES MELLITUS; DIABETIC NEUROPATHY; DOWN REGULATION; GLYCOLYSIS; HUMAN; HYDROXYLATION; HYPERGLYCEMIA; HYPOXIA; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REVIEW; SUMOYLATION; UBIQUITINATION; WOUND HEALING;

ANIMALS; ANOXIA; DIABETES MELLITUS; HUMANS; HYPERGLYCEMIA; HYPOXIA-INDUCIBLE FACTOR 1; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PATHOLOGIC;

EID: 79960904880     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2191-8     Document Type: Review

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