메뉴 건너뛰기




Volumn 2, Issue 8, 2010, Pages 302-310

Gender-related variations in iron metabolism and liver diseases

Author keywords

Alcohol; Hemochromatosis; Hepatitis C; Hepcidin; Non alcoholic steatohepatitis

Indexed keywords


EID: 79954597361     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v2.i8.302     Document Type: Article
Times cited : (69)

References (149)
  • 1
    • 47649126246 scopus 로고    scopus 로고
    • Forging a field: the golden age of iron biology
    • Andrews NC. Forging a field: the golden age of iron biology. Blood 2008; 112: 219-230
    • (2008) Blood , vol.112 , pp. 219-230
    • Andrews, N.C.1
  • 2
    • 33750133047 scopus 로고    scopus 로고
    • Regulation of iron metabolism by hepcidin
    • Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annu Rev Nutr 2006; 26: 323-342
    • (2006) Annu Rev Nutr , vol.26 , pp. 323-342
    • Nemeth, E.1    Ganz, T.2
  • 4
    • 34548115287 scopus 로고    scopus 로고
    • Minerals. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ
    • editors, 10 ed: Lippincott Williams & Wilkins
    • Wood R, Ronnenberg A. Minerals. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, editors. Modern nutrition in health and disease. 10 ed: Lippincott Williams & Wilkins, 2006: 248-271
    • (2006) Modern nutrition in health and disease , pp. 248-271
    • Wood, R.1    Ronnenberg, A.2
  • 6
    • 0033044583 scopus 로고    scopus 로고
    • Iron transport across biologic membranes
    • Andrews NC, Fleming MD, Gunshin H. Iron transport across biologic membranes. Nutr Rev 1999; 57: 114-123
    • (1999) Nutr Rev , vol.57 , pp. 114-123
    • Andrews, N.C.1    Fleming, M.D.2    Gunshin, H.3
  • 7
    • 0033957329 scopus 로고    scopus 로고
    • Iron requirements in adolescent females
    • Beard JL. Iron requirements in adolescent females. J Nutr 2000; 130: 440S-442S
    • (2000) J Nutr , vol.130
    • Beard, J.L.1
  • 8
    • 0034056566 scopus 로고    scopus 로고
    • Effectiveness and strategies of iron supplementation during pregnancy
    • Beard JL. Effectiveness and strategies of iron supplementation during pregnancy. Am J Clin Nutr 2000; 71: 1288S-1294S
    • (2000) Am J Clin Nutr , vol.71
    • Beard, J.L.1
  • 9
    • 33846650973 scopus 로고    scopus 로고
    • Molecular control of iron transport
    • Ganz T. Molecular control of iron transport. J Am Soc Nephrol 2007; 18: 394-400
    • (2007) J Am Soc Nephrol , vol.18 , pp. 394-400
    • Ganz, T.1
  • 10
    • 0036142230 scopus 로고    scopus 로고
    • Iron as a comorbid factor in chronic viral hepatitis
    • Bonkovsky HL. Iron as a comorbid factor in chronic viral hepatitis. Am J Gastroenterol 2002; 97: 1-4
    • (2002) Am J Gastroenterol , vol.97 , pp. 1-4
    • Bonkovsky, H.L.1
  • 11
    • 0037382796 scopus 로고    scopus 로고
    • Racial differences in the relationship between hepatitis C infection and iron stores
    • Ioannou GN, Dominitz JA, Weiss NS, Heagerty PJ, Kowdley KV. Racial differences in the relationship between hepatitis C infection and iron stores. Hepatology 2003; 37: 795-801
    • (2003) Hepatology , vol.37 , pp. 795-801
    • Ioannou, G.N.1    Dominitz, J.A.2    Weiss, N.S.3    Heagerty, P.J.4    Kowdley, K.V.5
  • 12
    • 2142809627 scopus 로고    scopus 로고
    • The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia
    • Ioannou GN, Dominitz JA, Weiss NS, Heagerty PJ, Kowdley KV. The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia. Gastroenterology 2004; 126: 1293-1301
    • (2004) Gastroenterology , vol.126 , pp. 1293-1301
    • Ioannou, G.N.1    Dominitz, J.A.2    Weiss, N.S.3    Heagerty, P.J.4    Kowdley, K.V.5
  • 14
    • 36349028180 scopus 로고    scopus 로고
    • Hemochromatosis: an endocrine liver disease
    • Pietrangelo A. Hemochromatosis: an endocrine liver disease. Hepatology 2007; 46: 1291-1301
    • (2007) Hepatology , vol.46 , pp. 1291-1301
    • Pietrangelo, A.1
  • 15
    • 69249233513 scopus 로고    scopus 로고
    • Role of hepatic iron in non-alcoholic steatohepatitis
    • Sumida Y, Yoshikawa T, Okanoue T. Role of hepatic iron in non-alcoholic steatohepatitis. Hepatol Res 2009; 39: 213-222
    • (2009) Hepatol Res , vol.39 , pp. 213-222
    • Sumida, Y.1    Yoshikawa, T.2    Okanoue, T.3
  • 16
    • 70350633968 scopus 로고    scopus 로고
    • Glucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overload
    • Lecube A, Hernández C, Simó R. Glucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overload. Diabetes Metab Res Rev 2009; 25: 403-410
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 403-410
    • Lecube, A.1    Hernández, C.2    Simó, R.3
  • 18
    • 0033730996 scopus 로고    scopus 로고
    • Inherited iron overload disorders
    • Andrews NC. Inherited iron overload disorders. Curr Opin Pediatr 2000; 12: 596-602
    • (2000) Curr Opin Pediatr , vol.12 , pp. 596-602
    • Andrews, N.C.1
  • 19
    • 0023194463 scopus 로고
    • Hypogonadotropic hypogonadism in hemochromatosis: recovery of reproductive function after iron depletion
    • Siemons LJ, Mahler CH. Hypogonadotropic hypogonadism in hemochromatosis: recovery of reproductive function after iron depletion. J Clin Endocrinol Metab 1987; 65: 585-587
    • (1987) J Clin Endocrinol Metab , vol.65 , pp. 585-587
    • Siemons, L.J.1    Mahler, C.H.2
  • 21
    • 16444363495 scopus 로고    scopus 로고
    • HFE gene mutations in susceptibility to childhood leukemia: HuGE review
    • Dorak MT, Burnett AK, Worwood M. HFE gene mutations in susceptibility to childhood leukemia: HuGE review. Genet Med 2005; 7: 159-168
    • (2005) Genet Med , vol.7 , pp. 159-168
    • Dorak, M.T.1    Burnett, A.K.2    Worwood, M.3
  • 24
    • 0023914804 scopus 로고
    • The common anemias
    • Beutler E. The common anemias. JAMA 1988; 259: 2433-2437
    • (1988) JAMA , vol.259 , pp. 2433-2437
    • Beutler, E.1
  • 26
    • 0033846355 scopus 로고    scopus 로고
    • Reversible hypogonadotrophic hypogonadism in sexually infantile male thalassaemic patients with transfusional iron overload
    • Chatterjee R, Katz M. Reversible hypogonadotrophic hypogonadism in sexually infantile male thalassaemic patients with transfusional iron overload. Clin Endocrinol (Oxf) 2000; 53: 33-42
    • (2000) Clin Endocrinol (Oxf) , vol.53 , pp. 33-42
    • Chatterjee, R.1    Katz, M.2
  • 27
    • 0027162099 scopus 로고
    • Prospective study of the hypothalamic-pituitary axis in thalassaemic patients who developed secondary amenorrhoea
    • Chatterjee R, Katz M, Cox TF, Porter JB. Prospective study of the hypothalamic-pituitary axis in thalassaemic patients who developed secondary amenorrhoea. Clin Endocrinol (Oxf) 1993; 39: 287-296
    • (1993) Clin Endocrinol (Oxf) , vol.39 , pp. 287-296
    • Chatterjee, R.1    Katz, M.2    Cox, T.F.3    Porter, J.B.4
  • 33
    • 0019985082 scopus 로고
    • Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic hemochromatosis
    • Chapman RW, Morgan MY, Laulicht M, Hoffbrand AV, Sherlock S. Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic hemochromatosis. Dig Dis Sci 1982; 27: 909-916
    • (1982) Dig Dis Sci , vol.27 , pp. 909-916
    • Chapman, R.W.1    Morgan, M.Y.2    Laulicht, M.3    Hoffbrand, A.V.4    Sherlock, S.5
  • 35
    • 34848886872 scopus 로고    scopus 로고
    • Role of alcohol in the regulation of iron metabolism
    • Harrison-Findik DD. Role of alcohol in the regulation of iron metabolism. World J Gastroenterol 2007; 13: 4925-4930
    • (2007) World J Gastroenterol , vol.13 , pp. 4925-4930
    • Harrison-Findik, D.D.1
  • 37
    • 58149302689 scopus 로고    scopus 로고
    • Iron in NASH, chronic liver diseases and HCC: how much iron is too much?
    • Pietrangelo A. Iron in NASH, chronic liver diseases and HCC: how much iron is too much? J Hepatol 2009; 50: 249-251
    • (2009) J Hepatol , vol.50 , pp. 249-251
    • Pietrangelo, A.1
  • 44
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C. The obsvirc, metavir, clinivir, and dosvirc groups
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The obsvirc, metavir, clinivir, and dosvirc groups. Lancet 1997; 349: 825-832
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 45
    • 0035009810 scopus 로고    scopus 로고
    • Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis c
    • Poynard T, Ratziu V, Charlotte F, Goodman Z, McHutchison J, Albrecht J. Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis c. J Hepatol 2001; 34: 730-739
    • (2001) J Hepatol , vol.34 , pp. 730-739
    • Poynard, T.1    Ratziu, V.2    Charlotte, F.3    Goodman, Z.4    McHutchison, J.5    Albrecht, J.6
  • 46
  • 49
    • 0030858597 scopus 로고    scopus 로고
    • Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophages
    • Lin M, Rippe RA, Niemelä O, Brittenham G, Tsukamoto H. Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophages. Am J Physiol 1997; 272: G1355-G1364
    • (1997) Am J Physiol , vol.272
    • Lin, M.1    Rippe, R.A.2    Niemelä, O.3    Brittenham, G.4    Tsukamoto, H.5
  • 50
    • 0024807066 scopus 로고
    • More rapid elimination of alcohol in women as compared to their male siblings
    • Mishra L, Sharma S, Potter JJ, Mezey E. More rapid elimination of alcohol in women as compared to their male siblings. Alcohol Clin Exp Res 1989; 13: 752-754
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 752-754
    • Mishra, L.1    Sharma, S.2    Potter, J.J.3    Mezey, E.4
  • 52
    • 0034054937 scopus 로고    scopus 로고
    • Influence of sex hormones on alcohol metabolism
    • Mezey E. Influence of sex hormones on alcohol metabolism. Alcohol Clin Exp Res 2000; 24: 421
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 421
    • Mezey, E.1
  • 53
    • 0023749353 scopus 로고
    • Influence of male hormones on rates of ethanol elimination in man
    • Mezey E, Oesterling JE, Potter JJ. Influence of male hormones on rates of ethanol elimination in man. Hepatology 1988; 8: 742-744
    • (1988) Hepatology , vol.8 , pp. 742-744
    • Mezey, E.1    Oesterling, J.E.2    Potter, J.J.3
  • 58
    • 65649112386 scopus 로고    scopus 로고
    • Is the iron regulatory hormone hepcidin a risk factor for alcoholic liver disease?
    • Harrison-Findik DD. Is the iron regulatory hormone hepcidin a risk factor for alcoholic liver disease? World J Gastroenterol 2009; 15: 1186-1193
    • (2009) World J Gastroenterol , vol.15 , pp. 1186-1193
    • Harrison-Findik, D.D.1
  • 59
    • 11244349748 scopus 로고    scopus 로고
    • Progress in understanding the pathogenesis of nonalcoholic fatty liver disease
    • Moseley RH. Progress in understanding the pathogenesis of nonalcoholic fatty liver disease. Hepatology 2005; 41: 204-206
    • (2005) Hepatology , vol.41 , pp. 204-206
    • Moseley, R.H.1
  • 60
    • 28844459409 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: from cell biology to clinical practice
    • Cortez-Pinto H, de Moura MC, Day CP. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol 2006; 44: 197-208
    • (2006) J Hepatol , vol.44 , pp. 197-208
    • Cortez-Pinto, H.1    de Moura, M.C.2    Day, C.P.3
  • 61
    • 0032771475 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Diehl AM. Nonalcoholic steatohepatitis. Semin Liver Dis 1999; 19: 221-229
    • (1999) Semin Liver Dis , vol.19 , pp. 221-229
    • Diehl, A.M.1
  • 62
    • 36249009634 scopus 로고    scopus 로고
    • Pathology of nonalcoholic fatty liver disease
    • Yeh MM, Brunt EM. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007; 128: 837-847
    • (2007) Am J Clin Pathol , vol.128 , pp. 837-847
    • Yeh, M.M.1    Brunt, E.M.2
  • 63
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43: S99-S112
    • (2006) Hepatology , vol.43
    • Farrell, G.C.1    Larter, C.Z.2
  • 64
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 2010; 51: 1820-1832
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 70
    • 0035003922 scopus 로고    scopus 로고
    • Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men--the Third National Health and Nutrition Examination Survey
    • Gillum RF. Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men--the Third National Health and Nutrition Examination Survey. Int J Obes Relat Metab Disord 2001; 25: 639-645
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 639-645
    • Gillum, R.F.1
  • 71
    • 23444453550 scopus 로고    scopus 로고
    • Iron stores, blood donation, and insulin sensitivity and secretion
    • Fernández-Real JM, López-Bermejo A, Ricart W. Iron stores, blood donation, and insulin sensitivity and secretion. Clin Chem 2005; 51: 1201-1205
    • (2005) Clin Chem , vol.51 , pp. 1201-1205
    • Fernández-Real, J.M.1    López-Bermejo, A.2    Ricart, W.3
  • 72
    • 33947159986 scopus 로고    scopus 로고
    • NAFLD and hyperinsulinemia are major determinants of serum ferritin levels
    • Zelber-Sagi S, Nitzan-Kaluski D, Halpern Z, Oren R. NAFLD and hyperinsulinemia are major determinants of serum ferritin levels. J Hepatol 2007; 46: 700-707
    • (2007) J Hepatol , vol.46 , pp. 700-707
    • Zelber-Sagi, S.1    Nitzan-Kaluski, D.2    Halpern, Z.3    Oren, R.4
  • 74
    • 0033562693 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: another disease of affluence
    • James O, Day C. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 1999; 353: 1634-1636
    • (1999) Lancet , vol.353 , pp. 1634-1636
    • James, O.1    Day, C.2
  • 75
    • 16444367799 scopus 로고    scopus 로고
    • Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents
    • Schwimmer JB, McGreal N, Deutsch R, Finegold MJ, Lavine JE. Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents. Pediatrics 2005; 115: e561-e565
    • (2005) Pediatrics , vol.115
    • Schwimmer, J.B.1    McGreal, N.2    Deutsch, R.3    Finegold, M.J.4    Lavine, J.E.5
  • 77
    • 0025178612 scopus 로고
    • The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years
    • Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 1990; 11: 74-80
    • (1990) Hepatology , vol.11 , pp. 74-80
    • Powell, E.E.1    Cooksley, W.G.2    Hanson, R.3    Searle, J.4    Halliday, J.W.5    Powell, L.W.6
  • 78
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003; 98: 960-967
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 84
    • 18244399587 scopus 로고    scopus 로고
    • Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
    • Gunshin H, Fujiwara Y, Custodio AO, Direnzo C, Robine S, Andrews NC. Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J Clin Invest 2005; 115: 1258-1266
    • (2005) J Clin Invest , vol.115 , pp. 1258-1266
    • Gunshin, H.1    Fujiwara, Y.2    Custodio, A.O.3    Direnzo, C.4    Robine, S.5    Andrews, N.C.6
  • 88
    • 0037962795 scopus 로고    scopus 로고
    • The orchestration of body iron intake: how and where do enterocytes receive their cues?
    • Frazer DM, Anderson GJ. The orchestration of body iron intake: how and where do enterocytes receive their cues? Blood Cells Mol Dis 2003; 30: 288-297
    • (2003) Blood Cells Mol Dis , vol.30 , pp. 288-297
    • Frazer, D.M.1    Anderson, G.J.2
  • 90
    • 0014192989 scopus 로고
    • Hereditary defect in iron absorption in mice
    • Pinkerton PH, Bannerman RM. Hereditary defect in iron absorption in mice. Nature 1967; 216: 482-483
    • (1967) Nature , vol.216 , pp. 482-483
    • Pinkerton, P.H.1    Bannerman, R.M.2
  • 92
    • 0032510424 scopus 로고    scopus 로고
    • Identification of carbohydrate deficient transferrin forms by MALDI-TOF mass spectrometry and lectin ELISA
    • Peter J, Unverzagt C, Engel WD, Renauer D, Seidel C, Hösel W. Identification of carbohydrate deficient transferrin forms by MALDI-TOF mass spectrometry and lectin ELISA. Biochim Biophys Acta 1998; 1380: 93-101
    • (1998) Biochim Biophys Acta , vol.1380 , pp. 93-101
    • Peter, J.1    Unverzagt, C.2    Engel, W.D.3    Renauer, D.4    Seidel, C.5    Hösel, W.6
  • 93
    • 0020318359 scopus 로고
    • The structural heterogeneity of the carbohydrate moiety of desialylated human transferrin
    • März L, Hatton MW, Berry LR, Regoeczi E. The structural heterogeneity of the carbohydrate moiety of desialylated human transferrin. Can J Biochem 1982; 60: 624-630
    • (1982) Can J Biochem , vol.60 , pp. 624-630
    • März, L.1    Hatton, M.W.2    Berry, L.R.3    Regoeczi, E.4
  • 95
    • 0025975369 scopus 로고
    • Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls
    • Stibler H, Borg S. Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls. Scand J Clin Lab Invest 1991; 51: 43-51
    • (1991) Scand J Clin Lab Invest , vol.51 , pp. 43-51
    • Stibler, H.1    Borg, S.2
  • 96
    • 47049116623 scopus 로고    scopus 로고
    • Clinical characteristics of carbohydrate- deficient transferrin (%disialotransferrin) measured by HPLC: sensitivity, specificity, gender effects, and relationship with other alcohol biomarkers
    • Bergström JP, Helander A. Clinical characteristics of carbohydrate- deficient transferrin (%disialotransferrin) measured by HPLC: sensitivity, specificity, gender effects, and relationship with other alcohol biomarkers. Alcohol Alcohol 2008; 43: 436-441
    • (2008) Alcohol Alcohol , vol.43 , pp. 436-441
    • Bergström, J.P.1    Helander, A.2
  • 97
    • 0032830130 scopus 로고    scopus 로고
    • The transferrin receptor: role in health and disease
    • Ponka P, Lok CN. The transferrin receptor: role in health and disease. Int J Biochem Cell Biol 1999; 31: 1111-1137
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 1111-1137
    • Ponka, P.1    Lok, C.N.2
  • 98
    • 0033597780 scopus 로고    scopus 로고
    • Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
    • Kawabata H, Yang R, Hirama T, Vuong PT, Kawano S, Gombart AF, Koeffler HP. Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. J Biol Chem 1999; 274: 20826-20832
    • (1999) J Biol Chem , vol.274 , pp. 20826-20832
    • Kawabata, H.1    Yang, R.2    Hirama, T.3    Vuong, P.T.4    Kawano, S.5    Gombart, A.F.6    Koeffler, H.P.7
  • 100
    • 0037020241 scopus 로고    scopus 로고
    • The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
    • Hunter HN, Fulton DB, Ganz T, Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem 2002; 277: 37597-37603
    • (2002) J Biol Chem , vol.277 , pp. 37597-37603
    • Hunter, H.N.1    Fulton, D.B.2    Ganz, T.3    Vogel, H.J.4
  • 101
    • 0035896581 scopus 로고    scopus 로고
    • A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
    • Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, Loréal O. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001; 276: 7811-7819
    • (2001) J Biol Chem , vol.276 , pp. 7811-7819
    • Pigeon, C.1    Ilyin, G.2    Courselaud, B.3    Leroyer, P.4    Turlin, B.5    Brissot, P.6    Loréal, O.7
  • 102
    • 36549034762 scopus 로고    scopus 로고
    • Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin
    • Valore EV, Ganz T. Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin. Blood Cells Mol Dis 2008; 40: 132-138
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 132-138
    • Valore, E.V.1    Ganz, T.2
  • 103
    • 36549006459 scopus 로고    scopus 로고
    • Commentary to: "Post-translational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin," by Erika Valore and Tomas Ganz
    • Lee P. Commentary to: "Post-translational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin," by Erika Valore and Tomas Ganz. Blood Cells Mol Dis 2008; 40: 139-140
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 139-140
    • Lee, P.1
  • 104
  • 105
    • 4344600507 scopus 로고    scopus 로고
    • Hepcidin in iron metabolism
    • Ganz T. Hepcidin in iron metabolism. Curr Opin Hematol 2004; 11: 251-254
    • (2004) Curr Opin Hematol , vol.11 , pp. 251-254
    • Ganz, T.1
  • 106
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98: 8780-8785
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8780-8785
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3    Beaumont, C.4    Grandchamp, B.5    Kahn, A.6    Vaulont, S.7
  • 109
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-1276
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3    Keller, C.4    Taudorf, S.5    Pedersen, B.K.6    Ganz, T.7
  • 110
    • 13844307889 scopus 로고    scopus 로고
    • Regulation of hepcidin transcription by interleukin-1 and interleukin-6
    • Lee P, Peng H, Gelbart T, Wang L, Beutler E. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci USA 2005; 102: 1906-1910
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1906-1910
    • Lee, P.1    Peng, H.2    Gelbart, T.3    Wang, L.4    Beutler, E.5
  • 113
    • 33846225653 scopus 로고    scopus 로고
    • Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload
    • Wallace DF, Summerville L, Subramaniam VN. Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload. Gastroenterology 2007; 132: 301-310
    • (2007) Gastroenterology , vol.132 , pp. 301-310
    • Wallace, D.F.1    Summerville, L.2    Subramaniam, V.N.3
  • 123
    • 2442681406 scopus 로고    scopus 로고
    • Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice
    • Krijt J, Cmejla R, Sýkora V, Vokurka M, Vyoral D, Necas E. Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice. J Hepatol 2004; 40: 891-896
    • (2004) J Hepatol , vol.40 , pp. 891-896
    • Krijt, J.1    Cmejla, R.2    Sýkora, V.3    Vokurka, M.4    Vyoral, D.5    Necas, E.6
  • 127
    • 0344514886 scopus 로고    scopus 로고
    • Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload
    • Biasiotto G, Belloli S, Ruggeri G, Zanella I, Gerardi G, Corrado M, Gobbi E, Albertini A, Arosio P. Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem 2003; 49: 1981-1988
    • (2003) Clin Chem , vol.49 , pp. 1981-1988
    • Biasiotto, G.1    Belloli, S.2    Ruggeri, G.3    Zanella, I.4    Gerardi, G.5    Corrado, M.6    Gobbi, E.7    Albertini, A.8    Arosio, P.9
  • 129
    • 1642367900 scopus 로고    scopus 로고
    • HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype
    • Jacolot S, Le Gac G, Scotet V, Quere I, Mura C, Ferec C. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. Blood 2004; 103: 2835-2840
    • (2004) Blood , vol.103 , pp. 2835-2840
    • Jacolot, S.1    Le Gac, G.2    Scotet, V.3    Quere, I.4    Mura, C.5    Ferec, C.6
  • 134
    • 10244225221 scopus 로고    scopus 로고
    • Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin
    • Krijt J, Vokurka M, Chang KT, Necas E. Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin. Blood 2004; 104: 4308-4310
    • (2004) Blood , vol.104 , pp. 4308-4310
    • Krijt, J.1    Vokurka, M.2    Chang, K.T.3    Necas, E.4
  • 138
    • 6944235898 scopus 로고    scopus 로고
    • The role of leptin in NAFLD: contender or pretender?
    • Poordad FF. The role of leptin in NAFLD: contender or pretender? J Clin Gastroenterol 2004; 38: 841-843
    • (2004) J Clin Gastroenterol , vol.38 , pp. 841-843
    • Poordad, F.F.1
  • 140
    • 0036204924 scopus 로고    scopus 로고
    • Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
    • Saxena NK, Ikeda K, Rockey DC, Friedman SL, Anania FA. Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 2002; 35: 762-771
    • (2002) Hepatology , vol.35 , pp. 762-771
    • Saxena, N.K.1    Ikeda, K.2    Rockey, D.C.3    Friedman, S.L.4    Anania, F.A.5
  • 141
    • 35848934560 scopus 로고    scopus 로고
    • Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells
    • Chung B, Matak P, McKie AT, Sharp P. Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells. J Nutr 2007; 137: 2366-2370
    • (2007) J Nutr , vol.137 , pp. 2366-2370
    • Chung, B.1    Matak, P.2    McKie, A.T.3    Sharp, P.4
  • 142
    • 0023189354 scopus 로고
    • Sex hormone changes in chronic liver disease: a matched study of alcoholic versus non-alcoholic liver disease
    • Bannister P, Oakes J, Sheridan P, Losowsky MS. Sex hormone changes in chronic liver disease: a matched study of alcoholic versus non-alcoholic liver disease. Q J Med 1987; 63: 305-313
    • (1987) Q J Med , vol.63 , pp. 305-313
    • Bannister, P.1    Oakes, J.2    Sheridan, P.3    Losowsky, M.S.4
  • 147
    • 0033563246 scopus 로고    scopus 로고
    • Overexpression and amplification of c-myc in the Syrian hamster kidney during estrogen carcinogenesis: a probable critical role in neoplastic transformation
    • Li JJ, Hou X, Banerjee SK, Liao DZ, Maggouta F, Norris JS, Li SA. Overexpression and amplification of c-myc in the Syrian hamster kidney during estrogen carcinogenesis: a probable critical role in neoplastic transformation. Cancer Res 1999; 59: 2340-2346
    • (1999) Cancer Res , vol.59 , pp. 2340-2346
    • Li, J.J.1    Hou, X.2    Banerjee, S.K.3    Liao, D.Z.4    Maggouta, F.5    Norris, J.S.6    Li, S.A.7
  • 148
    • 0033551393 scopus 로고    scopus 로고
    • The basic region/helix-loop-helix/ leucine zipper domain of Myc proto-oncoproteins: function and regulation
    • Lüscher B, Larsson LG. The basic region/helix-loop-helix/ leucine zipper domain of Myc proto-oncoproteins: function and regulation. Oncogene 1999; 18: 2955-2966
    • (1999) Oncogene , vol.18 , pp. 2955-2966
    • Lüscher, B.1    Larsson, L.G.2
  • 149
    • 33845477874 scopus 로고    scopus 로고
    • Cis and trans regulation of hepcidin expression by upstream stimulatory factor
    • Bayele HK, McArdle H, Srai SK. Cis and trans regulation of hepcidin expression by upstream stimulatory factor. Blood 2006; 108: 4237-4245
    • (2006) Blood , vol.108 , pp. 4237-4245
    • Bayele, H.K.1    McArdle, H.2    Srai, S.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.