메뉴 건너뛰기




Volumn 132, Issue 1, 2007, Pages 301-310

Targeted Disruption of the Hepatic Transferrin Receptor 2 Gene in Mice Leads to Iron Overload

Author keywords

[No Author keywords available]

Indexed keywords

CD71 ANTIGEN; FERRITIN; HEPCIDIN; IRON; MESSENGER RNA; TRANSFERRIN; TRANSFERRIN RECEPTOR 2;

EID: 33846225653     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2006.11.028     Document Type: Article
Times cited : (102)

References (39)
  • 1
    • 0036364659 scopus 로고    scopus 로고
    • Molecular and cellular characterization of transferrin receptor 2
    • Subramaniam V.N., Summerville L., and Wallace D.F. Molecular and cellular characterization of transferrin receptor 2. Cell Biochem Biophys 36 (2002) 235-239
    • (2002) Cell Biochem Biophys , vol.36 , pp. 235-239
    • Subramaniam, V.N.1    Summerville, L.2    Wallace, D.F.3
  • 2
    • 0037343705 scopus 로고    scopus 로고
    • Transferrin receptor 2: a new molecule in iron metabolism
    • Trinder D., and Baker E. Transferrin receptor 2: a new molecule in iron metabolism. Int J Biochem Cell Biol 35 (2003) 292-296
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 292-296
    • Trinder, D.1    Baker, E.2
  • 3
    • 33645888406 scopus 로고    scopus 로고
    • New insights into the regulation of iron homeostasis
    • Deicher R., and Horl W.H. New insights into the regulation of iron homeostasis. Eur J Clin Invest 36 (2006) 301-309
    • (2006) Eur J Clin Invest , vol.36 , pp. 301-309
    • Deicher, R.1    Horl, W.H.2
  • 4
    • 15244339138 scopus 로고    scopus 로고
    • Why do humans need two types of transferrin receptor?. Lessons from a rare genetic disorder
    • Camaschella C. Why do humans need two types of transferrin receptor?. Lessons from a rare genetic disorder. Haematologica 90 (2005) 296
    • (2005) Haematologica , vol.90 , pp. 296
    • Camaschella, C.1
  • 5
    • 0032830130 scopus 로고    scopus 로고
    • The transferrin receptor: role in health and disease
    • Ponka P., and Lok C.N. The transferrin receptor: role in health and disease. Int J Biochem Cell Biol 31 (1999) 1111-1137
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 1111-1137
    • Ponka, P.1    Lok, C.N.2
  • 6
    • 4143051431 scopus 로고    scopus 로고
    • Transferrin receptor 1
    • Aisen P. Transferrin receptor 1. Int J Biochem Cell Biol 36 (2004) 2137-2143
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2137-2143
    • Aisen, P.1
  • 7
    • 0032959574 scopus 로고    scopus 로고
    • Transferrin receptor is necessary for development of erythrocytes and the nervous system
    • Levy J.E., Jin O., Fujiwara Y., Kuo F., and Andrews N.C. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet 21 (1999) 396-399
    • (1999) Nat Genet , vol.21 , pp. 396-399
    • Levy, J.E.1    Jin, O.2    Fujiwara, Y.3    Kuo, F.4    Andrews, N.C.5
  • 10
    • 21044434748 scopus 로고    scopus 로고
    • First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin
    • Wallace D.F., Summerville L., Lusby P.E., and Subramaniam V.N. First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin. Gut 54 (2005) 980-986
    • (2005) Gut , vol.54 , pp. 980-986
    • Wallace, D.F.1    Summerville, L.2    Lusby, P.E.3    Subramaniam, V.N.4
  • 11
    • 0031605219 scopus 로고    scopus 로고
    • Transferrin, the transferrin receptor, and the uptake of iron by cells
    • Aisen P. Transferrin, the transferrin receptor, and the uptake of iron by cells. Met Ions Biol Syst 35 (1998) 585-631
    • (1998) Met Ions Biol Syst , vol.35 , pp. 585-631
    • Aisen, P.1
  • 13
    • 10244265904 scopus 로고    scopus 로고
    • Diferric transferrin regulates transferrin receptor 2 protein stability
    • Johnson M.B., and Enns C.A. Diferric transferrin regulates transferrin receptor 2 protein stability. Blood 104 (2004) 4287-4293
    • (2004) Blood , vol.104 , pp. 4287-4293
    • Johnson, M.B.1    Enns, C.A.2
  • 14
    • 10244255021 scopus 로고    scopus 로고
    • Regulation of transferrin receptor 2 protein levels by transferrin
    • Robb A., and Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood 104 (2004) 4294-4299
    • (2004) Blood , vol.104 , pp. 4294-4299
    • Robb, A.1    Wessling-Resnick, M.2
  • 15
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E., Tuttle M.S., Powelson J., Vaughn M.B., Donovan A., Ward D.M., Ganz T., and Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306 (2004) 2090-2093
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 21
    • 0033597780 scopus 로고    scopus 로고
    • Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
    • Kawabata H., Yang R., Hirama T., Vuong P.T., Kawano S., Gombart A.F., and Koeffler H.P. Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. J Biol Chem 274 (1999) 20826-20832
    • (1999) J Biol Chem , vol.274 , pp. 20826-20832
    • Kawabata, H.1    Yang, R.2    Hirama, T.3    Vuong, P.T.4    Kawano, S.5    Gombart, A.F.6    Koeffler, H.P.7
  • 22
    • 0037406254 scopus 로고    scopus 로고
    • Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells
    • Griffiths W.J., and Cox T.M. Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells. J Histochem Cytochem 51 (2003) 613-624
    • (2003) J Histochem Cytochem , vol.51 , pp. 613-624
    • Griffiths, W.J.1    Cox, T.M.2
  • 23
    • 0037111572 scopus 로고    scopus 로고
    • Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum
    • Deaglio S., Capobianco A., Cali A., Bellora F., Alberti F., Righi L., Sapino A., Camaschella C., and Malavasi F. Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum. Blood 100 (2002) 3782-3789
    • (2002) Blood , vol.100 , pp. 3782-3789
    • Deaglio, S.1    Capobianco, A.2    Cali, A.3    Bellora, F.4    Alberti, F.5    Righi, L.6    Sapino, A.7    Camaschella, C.8    Malavasi, F.9
  • 25
    • 0035525741 scopus 로고    scopus 로고
    • Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells
    • Kawabata H., Nakamaki T., Ikonomi P., Smith R.D., Germain R.S., and Koeffler H.P. Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells. Blood 98 (2001) 2714-2719
    • (2001) Blood , vol.98 , pp. 2714-2719
    • Kawabata, H.1    Nakamaki, T.2    Ikonomi, P.3    Smith, R.D.4    Germain, R.S.5    Koeffler, H.P.6
  • 29
    • 0036195189 scopus 로고    scopus 로고
    • Conditional alleles in mice: practical considerations for tissue-specific knockouts
    • Kwan K.M. Conditional alleles in mice: practical considerations for tissue-specific knockouts. Genesis 32 (2002) 49-62
    • (2002) Genesis , vol.32 , pp. 49-62
    • Kwan, K.M.1
  • 32
    • 2942608896 scopus 로고    scopus 로고
    • Inactivation of the murine Transferrin Receptor 2 gene using the Cre recombinase: loxP system
    • Wallace D.F., Tonks I.D., Zournazi A., Kay G.F., and Subramaniam V.N. Inactivation of the murine Transferrin Receptor 2 gene using the Cre recombinase: loxP system. Genesis 39 (2004) 38-41
    • (2004) Genesis , vol.39 , pp. 38-41
    • Wallace, D.F.1    Tonks, I.D.2    Zournazi, A.3    Kay, G.F.4    Subramaniam, V.N.5
  • 33
    • 21044450599 scopus 로고    scopus 로고
    • Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes
    • Wallace D.F., Summerville L., Lusby P.E., and Subramaniam V.N. Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes. J Hepatol 43 (2005) 720-728
    • (2005) J Hepatol , vol.43 , pp. 720-728
    • Wallace, D.F.1    Summerville, L.2    Lusby, P.E.3    Subramaniam, V.N.4
  • 34
    • 0014267781 scopus 로고
    • A simple technique for measuring storage iron concentrations in formalinised liver samples
    • Torrance J.D., and Bothwell T.H. A simple technique for measuring storage iron concentrations in formalinised liver samples. S Afr J Med Sci 33 (1968) 9-11
    • (1968) S Afr J Med Sci , vol.33 , pp. 9-11
    • Torrance, J.D.1    Bothwell, T.H.2
  • 36
    • 0842263988 scopus 로고    scopus 로고
    • Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
    • Zhang A.S., Xiong S., Tsukamoto H., and Enns C.A. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 103 (2004) 1509-1514
    • (2004) Blood , vol.103 , pp. 1509-1514
    • Zhang, A.S.1    Xiong, S.2    Tsukamoto, H.3    Enns, C.A.4
  • 38
    • 0038025679 scopus 로고    scopus 로고
    • Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload
    • Ilyin G., Courselaud B., Troadec M.B., Pigeon C., Alizadeh M., Leroyer P., Brissot P., and Loreal O. Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload. FEBS Lett 542 (2003) 22-26
    • (2003) FEBS Lett , vol.542 , pp. 22-26
    • Ilyin, G.1    Courselaud, B.2    Troadec, M.B.3    Pigeon, C.4    Alizadeh, M.5    Leroyer, P.6    Brissot, P.7    Loreal, O.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.