Estrogens receptors and oxidative damage in the liver

Molecular and Cellular Endocrinology

Volumn 193, Issue 1-2, 2002, Pages 85-88

  Farinati, Fabio ^a   Cardin, R ^a   Bortolami, M ^a   Grottola, A ^b   Manno, M ^b   Colantoni, A ^b   Villa, E ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

C myc; Chronic liver disease; Estrogens receptor; Hepatitis C virus; Hepatocellular carcinoma; Oxidative DNA damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

CELL PROLIFERATION; CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; CONFERENCE PAPER; DNA ADDUCT; DNA DAMAGE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER INJURY; NONHUMAN; ONCOGENE C MYC; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; ANIMAL; LIVER DISEASE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; REVIEW; VIROLOGY; VIRUS HEPATITIS;

ANIMALS; DNA DAMAGE; HEPATITIS, VIRAL, HUMAN; HUMANS; LIVER DISEASES; OXIDATIVE STRESS; RECEPTORS, ESTROGEN;

EID: 0037205892     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(02)00100-4     Document Type: Conference Paper

References (23)

1. 17β-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells
2. DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study
3. Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment
4. Dysregulation of apoptosis by c-myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens
5. Influence of sex hormonal status on alcohol-induced oxidative injury in male and female rat liver
6. Association between reactive oxygen species and disease activity in chronic hepatitis C
7. Iron storage, lipid peroxidation and glutathione turnover in chronic anti-HCV positive hepatitis
8. Oxidative DNA damage in circulating leukocytes occurs as an early event in chronic HCV infection
9. Imbalance between cytoproliferation and apoptosis in hepatitis C virus related chronic liver disease
10. Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones
11. Differential mechanisms of neuroprotection by 17β-estradiol in apoptotic versus necrotic neurodegeneration
12. Proteins of the Myc network: essential regulators of cell growth and differentiation
13. Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways
14. Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
15. Overexpression and amplification of c-myc in the Syrian Hamster kidney during estrogen carcinogenesis: a probable critical role in neoplastic transformation
16. Transcription activation by the human estrogen receptor subtype β (ERβ) studied with ERβ and ERα receptor chimeras
17. Role of reactive oxygen in synthetic estrogen induction of hepatocellular carcinomas in rats and preventive effects of vitamins
18. Cyclin A2 and c-myc mRNA expression in ethinyl estradiol induced liver proliferation
19. Estrogen, DNA damage and mutations
20. Ethanol-induced increase in cytosolic estrogen receptors in human male liver: a possible explanation for biochemical feminization in chronic liver disease due to alcohol
21. Variant liver estrogen receptor transcripts already occur at an early stage of chronic liver disease
22. Expression of c-Myc, c-Fos, and c-Jun in hepatocellular carcinoma
23. Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone