메뉴 건너뛰기




Volumn 49, Issue 1-3, 2011, Pages 70-86

Apoptosis and autophagy in the regulation of T lymphocyte function

Author keywords

Apoptosis; Autophagy; Bcl 2; c FLIP; Mcl 1; T lymphocytes

Indexed keywords

APOPTOSIS INDUCING FACTOR; BIM PROTEIN; CD28 ANTIGEN; CYTOCHROME C; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; FLICE INHIBITORY PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 15; INTERLEUKIN 7; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL X; PROTEIN BCL XL; PROTEIN BID; PROTEIN KINASE LCK; PROTEIN MCL 1; PROTEIN NOXA; PUMA PROTEIN; T LYMPHOCYTE RECEPTOR; TAMOXIFEN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; UNINDEXED DRUG;

EID: 79952696967     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-010-8195-5     Document Type: Review
Times cited : (25)

References (121)
  • 1
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • Jameson SC. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol. 2002;2:547-56. (Pubitemid 37328730)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.8 , pp. 547-556
    • Jameson, S.C.1
  • 3
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
    • DOI 10.1016/S1074-7613(00)80470-7
    • Murali-Krishna K, Altman JD, Suresh M, Sourdive DJ, Zajac AJ, Miller JD, Slansky J, Ahmed R. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity. 1998;8:177-87. (Pubitemid 28123745)
    • (1998) Immunity , vol.8 , Issue.2 , pp. 177-187
    • Murali-Krishna, K.1    Altman, J.D.2    Suresh, M.3    Sourdive, D.J.D.4    Zajac, A.J.5    Miller, J.D.6    Slansky, J.7    Ahmed, R.8
  • 5
    • 0842281645 scopus 로고    scopus 로고
    • Cell Death: Critical Control Points
    • DOI 10.1016/S0092-8674(04)00046-7
    • Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell. 2004;116:205-19. (Pubitemid 38167313)
    • (2004) Cell , vol.116 , Issue.2 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 6
    • 0038393112 scopus 로고    scopus 로고
    • Apoptosis in the development and maintenance of the immune system
    • DOI 10.1038/ni0503-410
    • Opferman JT, Korsmeyer SJ. Apoptosis in the development and maintenance of the immune system. Nat Immunol. 2003;4:410-5. (Pubitemid 36592430)
    • (2003) Nature Immunology , vol.4 , Issue.5 , pp. 410-415
    • Opferman, J.T.1    Korsmeyer, S.J.2
  • 7
    • 27844539406 scopus 로고    scopus 로고
    • The role of apoptosis in the development and function of T lymphocytes
    • DOI 10.1038/sj.cr.7290345
    • Zhang N, Hartig H, Dzhagalov I, Draper D, He YW. The role of apoptosis in the development and function of T lymphocytes. Cell Res. 2005;15:749-69. (Pubitemid 41653913)
    • (2005) Cell Research , vol.15 , Issue.10 , pp. 749-769
    • Zhang, N.1    Hartig, H.2    Dzhagalov, I.3    Draper, D.4    He, Y.W.5
  • 8
    • 77957054466 scopus 로고    scopus 로고
    • The mammalian target of rapamycin: Linking T Cell differentiation, function, and metabolism
    • Powell JD, Delgoffe GM. The mammalian target of rapamycin: linking T Cell differentiation, function, and metabolism. Immunity. 33:301-311.
    • Immunity , vol.33 , pp. 301-311
    • Powell, J.D.1    Delgoffe, G.M.2
  • 9
    • 0036078369 scopus 로고    scopus 로고
    • Homeostatic control of lymphocyte survival: Potential origins and implications
    • DOI 10.1038/ni0602-515
    • Plas DR, Rathmell JC, Thompson CB. Homeostatic control of lymphocyte survival: potential origins and implications. Nat Immunol. 2002;3:515-21. (Pubitemid 34662302)
    • (2002) Nature Immunology , vol.3 , Issue.6 , pp. 515-521
    • Plas, D.R.1    Rathmell, J.C.2    Thompson, C.B.3
  • 11
    • 34447629523 scopus 로고    scopus 로고
    • Innate and Adaptive Immunity through Autophagy
    • DOI 10.1016/j.immuni.2007.07.004, PII S1074761307003408
    • Schmid D, Munz C. Innate and adaptive immunity through autophagy. Immunity. 2007;27:11-21. (Pubitemid 47089030)
    • (2007) Immunity , vol.27 , Issue.1 , pp. 11-21
    • Schmid, D.1    Munz, C.2
  • 12
    • 75649112322 scopus 로고    scopus 로고
    • Autophagy and lymphocyte homeostasis
    • Pua HH, He YW. Autophagy and lymphocyte homeostasis. Curr Top Microbiol Immunol. 2009;335:85-105.
    • (2009) Curr Top Microbiol Immunol , vol.335 , pp. 85-105
    • Pua, H.H.1    He, Y.W.2
  • 13
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev. 2005;6:505-10.
    • (2005) Nat Rev , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 14
    • 13944273009 scopus 로고    scopus 로고
    • Autophagy and caspases: A new cell death program
    • Georgetown, Tex
    • Yu L, Lenardo MJ, Baehrecke EH. Autophagy and caspases: a new cell death program. Cell Cycle. 2004;3:1124-6. (Georgetown, Tex).
    • (2004) Cell Cycle , vol.3 , pp. 1124-1126
    • Yu, L.1    Lenardo, M.J.2    Baehrecke, E.H.3
  • 17
    • 0036850312 scopus 로고    scopus 로고
    • Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
    • DOI 10.1016/S0092-8674(02)01036-X
    • Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R, Green DR, Newmeyer DD. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell. 2002;111:331-42. (Pubitemid 35341388)
    • (2002) Cell , vol.111 , Issue.3 , pp. 331-342
    • Kuwana, T.1    Mackey, M.R.2    Perkins, G.3    Ellisman, M.H.4    Latterich, M.5    Schneiter, R.6    Green, D.R.7    Newmeyer, D.D.8
  • 20
    • 0036794390 scopus 로고    scopus 로고
    • Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis
    • DOI 10.1038/ni834
    • Rathmell JC, Lindsten T, Zong WX, Cinalli RM, Thompson CB. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nat Immunol. 2002;3:932-9. (Pubitemid 35154006)
    • (2002) Nature Immunology , vol.3 , Issue.10 , pp. 932-939
    • Rathmell, J.C.1    Lindsten, T.2    Zong, W.-X.3    Cinalli, R.M.4    Thompson, C.B.5
  • 23
    • 0034786019 scopus 로고    scopus 로고
    • BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
    • Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell. 2001;8:705-11.
    • (2001) Mol Cell , vol.8 , pp. 705-711
    • Cheng, E.H.1    Wei, M.C.2    Weiler, S.3    Flavell, R.A.4    Mak, T.W.5    Lindsten, T.6    Korsmeyer, S.J.7
  • 24
    • 13944277343 scopus 로고    scopus 로고
    • BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
    • DOI 10.1016/j.molcel.2005.02.003
    • Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell. 2005;17:525-35. (Pubitemid 40269117)
    • (2005) Molecular Cell , vol.17 , Issue.4 , pp. 525-535
    • Kuwana, T.1    Bouchier-Hayes, L.2    Chipuk, J.E.3    Bonzon, C.4    Sullivan, B.A.5    Green, D.R.6    Newmeyer, D.D.7
  • 25
    • 0036728834 scopus 로고    scopus 로고
    • Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
    • DOI 10.1016/S1535-6108(02)00127-7
    • Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell. 2002;2:183-92. (Pubitemid 41043974)
    • (2002) Cancer Cell , vol.2 , Issue.3 , pp. 183-192
    • Letai, A.1    Bassik, M.C.2    Walensky, L.D.3    Sorcinelli, M.D.4    Weiler, S.5    Korsmeyer, S.J.6
  • 26
    • 19944432123 scopus 로고    scopus 로고
    • Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
    • DOI 10.1016/j.molcel.2004.12.030, PII S1097276505010403
    • Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell. 2005;17:393-403. (Pubitemid 40193310)
    • (2005) Molecular Cell , vol.17 , Issue.3 , pp. 393-403
    • Chen, L.1    Willis, S.N.2    Wei, A.3    Smith, B.J.4    Fletcher, J.I.5    Hinds, M.G.6    Colman, P.M.7    Day, C.L.8    Adams, J.M.9    Huang, D.C.S.10
  • 29
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • DOI 10.1016/0092-8674(93)80065-M
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypo pigmented hair. Cell. 1993;75:229-40. (Pubitemid 23320287)
    • (1993) Cell , vol.75 , Issue.2 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 30
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2 alpha beta in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama K, Nakayama K, Negishi I, Kuida K, Sawa H, Loh DY. Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci USA. 1994;91:3700-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Nakayama, K.2    Negishi, I.3    Kuida, K.4    Sawa, H.5    Loh, D.Y.6
  • 33
    • 13844319184 scopus 로고    scopus 로고
    • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
    • DOI 10.1126/science.1106114
    • Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ. Obligate role of antiapoptotic MCL-1 in the survival of hematopoietic stem cells. Science. 2005;307:1101-4. (Pubitemid 40262114)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1101-1104
    • Opferman, J.T.1    Iwasaki, H.2    Ong, C.C.3    Suh, H.4    Mizuno, S.-I.5    Akashi, K.6    Korsmeyer, S.J.7
  • 34
    • 0348148880 scopus 로고    scopus 로고
    • Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
    • DOI 10.1038/nature02067
    • Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature. 2003;426:671-6. (Pubitemid 38009376)
    • (2003) Nature , vol.426 , Issue.6967 , pp. 671-676
    • Opferman, J.T.1    Letai, A.2    Beard, C.3    Sorcinelli, M.D.4    Ong, C.C.5    Korsmeyer, S.J.6
  • 35
    • 47949126029 scopus 로고    scopus 로고
    • The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages
    • Dzhagalov I, Dunkle A, He YW. The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages. J Immunol. 2008;181:521-8.
    • (2008) J Immunol , vol.181 , pp. 521-528
    • Dzhagalov, I.1    Dunkle, A.2    He, Y.W.3
  • 36
    • 33846914830 scopus 로고    scopus 로고
    • The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages
    • DOI 10.1182/blood-2006-03-013771
    • Dzhagalov I, St John A, He Y-W. The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages. Blood. 2007;109:1620-6. (Pubitemid 46239596)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1620-1626
    • Dzhagalov, I.1    St, J.A.2    He, Y.-W.3
  • 37
    • 14944348965 scopus 로고    scopus 로고
    • The role of BH3-only proteins in the immune system
    • DOI 10.1038/nri1568
    • Strasser A. The role of BH3-only proteins in the immune system. Nat Rev Immunol. 2005;5:189-200. (Pubitemid 40364821)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.3 , pp. 189-200
    • Strasser, A.1
  • 38
    • 0027199233 scopus 로고
    • Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes
    • Veis DJ, Sentman CL, Bach EA, Korsmeyer SJ. Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J Immunol. 1993;151:2546-54. (Pubitemid 23264507)
    • (1993) Journal of Immunology , vol.151 , Issue.5 , pp. 2546-2554
    • Veis, D.J.1    Sentman, C.L.2    Bach, E.A.3    Korsmeyer, S.J.4
  • 39
    • 0027248447 scopus 로고
    • Bcl-2 Proto-oncogene expression during human T cell development: Evidence for biphasic regulation
    • Gratiot-Deans J, Ding L, Turka LA, Nunez G. Bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation. J Immunol. 1993;151:83-91. (Pubitemid 23206973)
    • (1993) Journal of Immunology , vol.151 , Issue.1 , pp. 83-91
    • Gratiot-Deans, J.1    Ding, L.2    Turka, L.A.3    Nunez, G.4
  • 41
    • 0028970662 scopus 로고
    • Bcl-xl displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice
    • Grillot DA, Merino R, Nunez G. Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice. J Exp Med. 1995;182:1973-83. (Pubitemid 3007453)
    • (1995) Journal of Experimental Medicine , vol.182 , Issue.6 , pp. 1973-1983
    • Grillot, D.A.1    Merino, R.2    Nunez, G.3
  • 46
    • 0030893390 scopus 로고    scopus 로고
    • Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell
    • Matsuzaki Y, Nakayama K, Nakayama K, Tomita T, Isoda M, Loh DY, Nakauchi H. Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. Blood. 1997;89:853-62. (Pubitemid 27121278)
    • (1997) Blood , vol.89 , Issue.3 , pp. 853-862
    • Matsuzaki, Y.1    Nakayama, K.-I.2    Nakayama, K.3    Tomita, T.4    Isoda, M.5    Loh, D.Y.6    Nakauchi, H.7
  • 48
    • 18944372860 scopus 로고    scopus 로고
    • L is dispensable for the development of effector and memory T lymphocytes
    • Zhang N, He YW. The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. J Immunol. 2005;174:6967-73. (Pubitemid 40705661)
    • (2005) Journal of Immunology , vol.174 , Issue.11 , pp. 6967-6973
    • Zhang, N.1    He, Y.-W.2
  • 53
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F, Adams JM, Strasser A. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 1999;286:1735-8. (Pubitemid 129515880)
    • (1999) Science , vol.286 , Issue.5445 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.S.3    Tarlinton, D.M.4    Kay, T.W.H.5    Kontgen, F.6    Adams, J.M.7    Strasser, A.8
  • 56
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim
    • DOI 10.1016/S1074-7613(02)00322-9
    • Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 2002;16:759-67. (Pubitemid 34786475)
    • (2002) Immunity , vol.16 , Issue.6 , pp. 759-767
    • Hildeman, D.A.1    Zhu, Y.2    Mitchell, T.C.3    Bouillet, P.4    Strasser, A.5    Kappler, J.6    Marrack, P.7
  • 58
    • 0035514046 scopus 로고    scopus 로고
    • Degenerative Disorders Caused by Bcl-2 Deficiency Prevented by Loss of Its BH3-Only Antagonist Bim
    • DOI 10.1016/S1534-5807(01)00083-1, PII S1534580701000831
    • Bouillet P, Cory S, Zhang LC, Strasser A, Adams JM. Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev Cell. 2001;1:645-53. (Pubitemid 33586117)
    • (2001) Developmental Cell , vol.1 , Issue.5 , pp. 645-653
    • Bouillet, P.1    Cory, S.2    Zhang, L.-C.3    Strasser, A.4    Adams, J.M.5
  • 60
    • 0032055166 scopus 로고    scopus 로고
    • Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation
    • Domen J, Gandy KL, Weissman IL. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood. 1998;91:2272-82. (Pubitemid 28155500)
    • (1998) Blood , vol.91 , Issue.7 , pp. 2272-2282
    • Domen, J.1    Gandy, K.L.2    Weissman, I.L.3
  • 61
    • 77952242695 scopus 로고    scopus 로고
    • Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2
    • Dunkle A, Dzhagalov I, He YW. Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2. Cell Death Differ. 2010;17:994-1002.
    • (2010) Cell Death Differ , vol.17 , pp. 994-1002
    • Dunkle, A.1    Dzhagalov, I.2    He, Y.W.3
  • 66
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- And CD- 95-induced apoptosis
    • DOI 10.1074/jbc.272.28.17255
    • Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem. 1997;272:17255-7. (Pubitemid 27311147)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.28 , pp. 17255-17257
    • Hu, S.1    Vincenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 69
    • 0030746740 scopus 로고    scopus 로고
    • Casper is a FADD- And caspase-related inducer of apoptosis
    • DOI 10.1016/S1074-7613(00)80450-1
    • Shu HB, Halpin DR, Goeddel DV. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 1997;6:751-63. (Pubitemid 27305737)
    • (1997) Immunity , vol.6 , Issue.6 , pp. 751-763
    • Shu, H.-B.1    Halpin, D.R.2    Goeddel, D.V.3
  • 72
    • 40949149811 scopus 로고    scopus 로고
    • R, the only murine short FLIP isoform, reveal requirements for DISC recruitment
    • DOI 10.1038/sj.cdd.4402314, PII 4402314, The biology of Hypoxia-inducible factors
    • Ueffing N, Keil E, Freund C, Kuhne R, Schulze-Osthoff K, Schmitz I. Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment. Cell Death Differ. 2008;15:773-82. (Pubitemid 351405082)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 773-782
    • Ueffing, N.1    Keil, E.2    Freund, C.3    Kuhne, R.4    Schulze-Osthoff, K.5    Schmitz, I.6
  • 73
    • 0035496099 scopus 로고    scopus 로고
    • Regulation of lymphocyte proliferation and death by flip
    • Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol. 2001;1:50-8. (Pubitemid 33741975)
    • (2001) Nature Reviews Immunology , vol.1 , Issue.1 , pp. 50-58
    • Thome, M.1    Tschopp, J.2
  • 74
    • 33344476184 scopus 로고    scopus 로고
    • CFLIP regulation of lymphocyte activation and development
    • DOI 10.1038/nri1787
    • Budd RC, Yeh WC, Tschopp J. cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol. 2006;6:196-204. (Pubitemid 43290989)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 196-204
    • Budd, R.C.1    Yeh, W.-C.2    Tschopp, J.3
  • 78
    • 17844361968 scopus 로고    scopus 로고
    • + T cell activation through caspase-8-dependent NF-kappaB activation
    • Dohrman A, Kataoka T, Cuenin S, Russell JQ, Tschopp J, Budd RC. Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation. J Immunol. 2005;174:5270-8. (Pubitemid 40593165)
    • (2005) Journal of Immunology , vol.174 , Issue.9 , pp. 5270-5278
    • Dohrman, A.1    Kataoka, T.2    Cuenin, S.3    Russell, J.Q.4    Tschopp, J.5    Budd, R.C.6
  • 79
    • 21244449877 scopus 로고    scopus 로고
    • Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8
    • Dohrman A, Russell JQ, Cuenin S, Fortner K, Tschopp J, Budd RC. Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8. J Immunol. 2005;175:311-8. (Pubitemid 40884333)
    • (2005) Journal of Immunology , vol.175 , Issue.1 , pp. 311-318
    • Dohrman, A.1    Russell, J.Q.2    Cuenin, S.3    Fortner, K.4    Tschopp, J.5    Budd, R.C.6
  • 80
    • 0028980902 scopus 로고
    • Fas and Fas ligand. lpr and gld mutations
    • Nagata S, Suda T. Fas and Fas ligand. lpr and gld mutations. Immunol Today. 1995;16:39-43.
    • (1995) Immunol Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 81
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature. 1992;356:314-7.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 82
    • 0037833695 scopus 로고    scopus 로고
    • The role of CD95 in the regulation of peripheral T-cell apoptosis
    • DOI 10.1034/j.1600-065X.2003.00047.x
    • Krueger A, Fas SC, Baumann S, Krammer PH. The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol Rev. 2003;193:58-69. (Pubitemid 36688040)
    • (2003) Immunological Reviews , vol.193 , pp. 58-69
    • Krueger, A.1    Fas, S.C.2    Baumann, S.3    Krammer, P.H.4
  • 83
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • DOI 10.1034/j.1600-065X.2003.00051.x
    • Green DR, Droin N, Pinkoski M. Activation-induced cell death in T cells. Immunol Rev. 2003;193:70-81. (Pubitemid 36688041)
    • (2003) Immunological Reviews , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 84
    • 0342470585 scopus 로고    scopus 로고
    • Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1)
    • DOI 10.1002/1521-4141(200002)30:2<678::AID-IMMU678>3.0.CO;2-Q
    • Reich A, Korner H, Sedgwick JD, Pircher H. Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1). Eur J Immunol. 2000;30:678-82. (Pubitemid 30098863)
    • (2000) European Journal of Immunology , vol.30 , Issue.2 , pp. 678-682
    • Reich, A.1    Korner, H.2    Sedgwick, J.D.3    Pircher, H.4
  • 85
    • 0033956309 scopus 로고    scopus 로고
    • TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions
    • DOI 10.1002/1521-4141(200002)30:2<683::AID-IMMU683>3.0.CO;2-5
    • Nguyen LT, McKall-Faienza K, Zakarian A, Speiser DE, Mak TW, Ohashi PS. TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide-induced deletion under limited conditions. Eur J Immunol. 2000;30:683-8. (Pubitemid 30098864)
    • (2000) European Journal of Immunology , vol.30 , Issue.2 , pp. 683-688
    • Nguyen, L.T.1    McKall-Faienza, K.2    Zakarian, A.3    Speiser, D.E.4    Mak, T.W.5    Ohashi, P.S.6
  • 86
    • 38949119408 scopus 로고    scopus 로고
    • Apoptosis Regulators Fas and Bim Cooperate in Shutdown of Chronic Immune Responses and Prevention of Autoimmunity
    • DOI 10.1016/j.immuni.2007.12.017, PII S107476130800037X
    • Hughes PD, Belz GT, Fortner KA, Budd RC, Strasser A, Bouillet P. Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity. 2008;28:197-205. (Pubitemid 351215234)
    • (2008) Immunity , vol.28 , Issue.2 , pp. 197-205
    • Hughes, P.D.1    Belz, G.T.2    Fortner, K.A.3    Budd, R.C.4    Strasser, A.5    Bouillet, P.6
  • 87
    • 38949210228 scopus 로고    scopus 로고
    • + T Cell Contraction
    • DOI 10.1016/j.immuni.2007.12.014, PII S1074761308000344
    • Weant AE, Michalek RD, Khan IU, Holbrook BC, Willingham MC, Grayson JM. Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction. Immunity. 2008;28:218-30. (Pubitemid 351215232)
    • (2008) Immunity , vol.28 , Issue.2 , pp. 218-230
    • Weant, A.E.1    Michalek, R.D.2    Khan, I.U.3    Holbrook, B.C.4    Willingham, M.C.5    Grayson, J.M.6
  • 89
    • 23744456144 scopus 로고    scopus 로고
    • An essential role for c-FLIP in the efficient development of mature T lymphocytes
    • DOI 10.1084/jem.20050117
    • Zhang N, He Y-W. An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med. 2005;202:395-404. (Pubitemid 41126957)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.3 , pp. 395-404
    • Zhang, N.1    He, Y.-W.2
  • 91
    • 54049130409 scopus 로고    scopus 로고
    • c-FLIP protects mature T lymphocytes from TCR-mediated killing
    • Zhang N, Hopkins K, He Y-W. c-FLIP protects mature T lymphocytes from TCR-mediated killing. J Immunol. 2008;181:5368-73.
    • (2008) J Immunol , vol.181 , pp. 5368-5373
    • Zhang, N.1    Hopkins, K.2    He, Y.-W.3
  • 92
    • 45949102790 scopus 로고    scopus 로고
    • The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-{kappa}B-independent pathway
    • Zhang N, Hopkins K, He Y-W. The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-{kappa}B-independent pathway. J Immunol. 2008;180:5506-11.
    • (2008) J Immunol , vol.180 , pp. 5506-5511
    • Zhang, N.1    Hopkins, K.2    He, Y.-W.3
  • 93
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • DOI 10.1126/science.290.5497.1717
    • Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science. 2000;290:1717-21. (Pubitemid 32004796)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 94
  • 95
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • DOI 10.1016/0014-5793(93)80398-E
    • Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993;333:169-74. (Pubitemid 23306962)
    • (1993) FEBS Letters , vol.333 , Issue.1-2 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 96
    • 0027936092 scopus 로고
    • Isolation of autophagocytosis mutants of Saccharomyces cerevisiae
    • DOI 10.1016/0014-5793(94)00672-5
    • Thumm M, Egner R, Koch B, Schlumpberger M, Straub M, Veenhuis M, Wolf DH. Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. FEBS Lett. 1994;349:275-80. (Pubitemid 24263277)
    • (1994) FEBS Letters , vol.349 , Issue.2 , pp. 275-280
    • Thumm, M.1
  • 100
    • 0042707790 scopus 로고    scopus 로고
    • Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis
    • DOI 10.1016/S0531-5565(03)00114-1
    • Terman A, Dalen H, Eaton JW, Neuzil J, Brunk UT. Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis. Exp Gerontol. 2003;38:863-76. (Pubitemid 36952668)
    • (2003) Experimental Gerontology , vol.38 , Issue.8 , pp. 863-876
    • Terman, A.1    Dalen, H.2    Eaton, J.W.3    Neuzil, J.4    Brunk, U.T.5
  • 102
    • 34250796793 scopus 로고    scopus 로고
    • Selective and non-selective autophagic degradation of mitochondria in yeast
    • Kissova I, Salin B, Schaeffer J, Bhatia S, Manon S, Camougrand N. Selective and non-selective autophagic degradation of mitochondria in yeast. Autophagy. 2007;3:329-36. (Pubitemid 46986337)
    • (2007) Autophagy , vol.3 , Issue.4 , pp. 329-336
    • Kissova, I.1    Salin, B.2    Schaeffer, J.3    Bhatia, S.4    Manon, S.5    Camougrand, N.6
  • 104
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • DOI 10.1038/nature07006, PII NATURE07006
    • Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, Wang J. Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008;454:232-5. (Pubitemid 351969889)
    • (2008) Nature , vol.454 , Issue.7201 , pp. 232-235
    • Sandoval, H.1    Thiagarajan, P.2    Dasgupta, S.K.3    Schumacher, A.4    Prchal, J.T.5    Chen, M.6    Wang, J.7
  • 105
    • 0035487007 scopus 로고    scopus 로고
    • The mitochondrial permeability transition initiates autophagy in rat hepatocytes
    • Elmore SP, Qian T, Grissom SF, Lemasters JJ. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. Faseb J. 2001;15:2286-7.
    • (2001) Faseb J , vol.15 , pp. 2286-2287
    • Elmore, S.P.1    Qian, T.2    Grissom, S.F.3    Lemasters, J.J.4
  • 107
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
    • DOI 10.1126/science.1096645
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, Baehrecke EH, Lenardo MJ. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science. 2004;304:1500-2. (Pubitemid 38720930)
    • (2004) Science , vol.304 , Issue.5676 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6    Baehrecke, E.H.7    Lenardo, M.J.8
  • 113
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell. 2004;119:753-66. (Pubitemid 40017683)
    • (2004) Cell , vol.119 , Issue.6 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 117
    • 33846461678 scopus 로고    scopus 로고
    • A critical role for the autophagy gene Atg5 in T cell survival and proliferation
    • DOI 10.1084/jem.20061303
    • Pua HH, Dzhagalov I, Chuck M, Mizushima N, He YW. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med. 2007;204:25-31. (Pubitemid 46148752)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.1 , pp. 25-31
    • Pua, H.H.1    Dzhagalov, I.2    Chuck, M.3    Mizushima, N.4    He, Y.-W.5
  • 118
    • 64249123646 scopus 로고    scopus 로고
    • Autophagy is essential for mitochondrial clearance in mature T lymphocytes
    • Pua HH, Guo J, Komatsu M, He Y-W. Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol. 2009;182:4046-55.
    • (2009) J Immunol , vol.182 , pp. 4046-4055
    • Pua, H.H.1    Guo, J.2    Komatsu, M.3    He, Y.-W.4
  • 119
  • 120
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 1998;94:491-501. (Pubitemid 28391865)
    • (1998) Cell , vol.94 , Issue.4 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.-J.3    Yuan, J.4
  • 121
    • 0037833701 scopus 로고    scopus 로고
    • Death and Baxes: Mechanisms of lymphotrophic cytokines
    • DOI 10.1034/j.1600-065X.2003.00050.x
    • Khaled AR, Durum SK. Death and baxes: mechanisms of lymphotrophic cytokines. Immunol Rev. 2003;193:48-57. (Pubitemid 36688039)
    • (2003) Immunological Reviews , vol.193 , pp. 48-57
    • Khaled, A.R.1    Durum, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.