Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2

Cell Death and Differentiation

Volumn 17, Issue 6, 2010, Pages 994-1002

  Dunkle, A ^a   Dzhagalov, I ^a   He, Y W ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bak; Bcl 2; Mcl 1; Thymocyte survival

Indexed keywords

BIM PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; GENE DELETION; GENE OVEREXPRESSION; GENETIC MODEL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CELL SURVIVAL; GENE DELETION; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MODELS, GENETIC; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; T-LYMPHOCYTES; THYMUS GLAND;

EID: 77952242695     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.201     Document Type: Article

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